Abstract: A fan-shaped air suction spray nozzle automatically adjusting an air suction speed is provided in the present invention, which includes a spray nozzle body and a liquid channel, the spray nozzle body being provided with a liquid channel in communication with a nozzle hole, and further includes a pressure groove and an air intake channel, wherein an inlet section of the liquid channel is in communication with the pressure groove, and the air intake channel is in communication with the liquid channel after penetrating through the pressure groove; an air intake orifice plate is installed in the pressure groove through an elastic damping apparatus, and a change of the pressure at an inlet of the liquid channel causes the air intake orifice plate to move between the pressure groove and the air intake channel; the air intake orifice plate is provided with several through holes of the same or different sizes, which are configured to change the air intake volume in the liquid channel as the air intake orifice plate m

Abstract: The present disclosure provides methods of treating cancer in a patient determined to have a p53 mutation by administering an inhibitor of nonsense mediated decay. The patient may be further administered an inhibitor of mRNA splicing and/or an inhibitor of MDM.

Abstract: The present invention is directed to a transgenic soybean plant having increased oleic acid content comprising a polynucleotide comprising a fatty acid thioesterase (FAT) related promoter that functions in the soybean plant operably linked to a polynucleotide encoding a polypeptide having FAT activity. The invention is further directed to a method of increasing oleic acid content of a soybean plant comprising transforming a soybean plant with a polynucleotide comprising a fatty acid thioesterase (FAT) related promoter that functions in the soybean plant operably linked to a polynucleotide encoding a polypeptide having FAT activity.

Abstract: Systems and methods for passive radiative cooling via structures attached to vertical (e.g. walls of buildings) or horizontal surfaces (e.g. roofs) with limited view of the sky by specifically radiating heat in the long-wavelength infrared window of the atmosphere, and designs for doing so are provided.

Abstract: Wirelessly powered implantable pulse generators (IPG) are described. In an embodiment, a wirelessly powered stimulator, includes an implantable pulse generator (IPG), including: an Rx antenna that receives a radio frequency (RF) signal from an external Tx antenna; a rectifier; an energy storage capacitor CSTOR, where the RF signal coupled to the Rx antenna is rectified by the rectifier to generate VDD and charges the CSTOR; a demodulator; an output voltage regulator that generates a stable voltage to activate the demodulator; and where the demodulator outputs a stimulation that releases the energy stored in the CSTOR on an electrode based on detecting amplitude modulation in the received RF signal; and a Tx antenna that generates the RF signal that wirelessly powers the IPG and that controls timing of output stimulations of the IPG, where amplitude modulation is applied to the RF signal to control the timing of the output stimulations.

Abstract: The present invention belongs to the field of microbiology, and particularly relates to membrane vesicles (MVs) isolated from bacteria, and an isolation and preparation system and method for the membrane vesicles, and applications of the membrane vesicles. The bacteria of the present invention comprise Gram-positive bacteria and Gram-negative bacteria. The invention uses ionizing irradiation to irradiate bacteria, and isolates and purifies the produced membrane vesicles. The membrane vesicles prepared can be used as a vaccine, a vaccine adjuvant and/or a pharmaceutical carrier. In addition, the present invention provides a biological composition comprising the membrane vesicles and inactivated bacteria. In addition, the present invention also provides a preparation system, and isolation and purification system for bacterial membrane vesicles and the corresponding method. The membrane vesicles obtained by using the system and method have high yield, high purity and easy to be industrialized.

Abstract: Disclosed in the present invention are a low energy consumption anhydrous CO2 phase change absorption agent, and a regeneration method and an application thereof, the absorption agent using a unitary diamine with a primary amine (NH2—) and a tertiary amine (—N—), and not containing any other organic solvent, water, and ionic liquid; two alkyl branches are linked to a nitrogen atom of the tertiary amine, forming a certain hydrophobicity; after absorbing the CO2, the diamine changes from a liquid phase to a solid phase, undergoing liquid-solid phase change to form white amino formate crystals.

Abstract: The invention relates to a Novosphingobium sp. SJB007 and an application thereof in removal of phosphorus from wastewater, belonging to the technical field of environmental microorganisms. One aspect of the invention provides a Novosphingobium sp. SJB007 with an access number of CGMCC (China General Microbiological Culture Collection Center) No. 21177. Another aspect of the invention provides an application of the Novosphingobium sp. SJB007 in removal of phosphorus from wastewater. The efficient phosphorus-accumulating strain Novosphingobium sp. SJB007 provided by the invention has a high removal rate of more than 97% when the concentration of phosphorus in the wastewater is 10-30 mg/L under an appropriate condition.

Abstract: This disclosure provides a fetal-blood-oxygen-saturation estimation technique using a deep neural network without performing explicit fetal signal extraction from mixed maternal-fetal photoplethysmogram (PPG) signals. In one aspect, the disclosed fetal-blood-oxygen-saturation estimation technique receives multiple channels of PPG signals from two or more photodetectors detecting transabdominal diffused light from two or more light sources emitting two or more distinct wavelengths, wherein the photodetectors and light sources are positioned on a maternal abdomen. Note that each channel of the multiple channels of PPG signals includes mixed maternal-fetal PPG signals.

Abstract: In certain embodiments a lentiviral vector for the treatment of X-linked chronic granulomatous disease (X-CGD) is provided. In certain embodiments the vector comprises an expression cassette comprising a nucleic acid construct comprising a CYBB promoter or effective fragment thereof; and a nucleic acid that encodes gp91phox operably linked to the CYBB promoter or promoter fragment.

Abstract: A twistable electronic device module including a twistable substrate, an electrode pattern layer, an insulating layer, a circuit layer, a plurality of circuit boards and a plurality of electronic devices is provided. The electrode pattern layer is disposed on the twistable substrate. The insulating layer is disposed on the electrode pattern layer. The edge of the insulating layer has an opening located at the edge of the twistable substrate and exposing a part of the electrode pattern layer. The circuit layer is disposed on the insulating layer and on the sidewall of the opening, and is connected with the electrode pattern layer. The plurality of circuit boards are disposed on the circuit layer, and each is electrically connected to the circuit layer.

Abstract: A cabazitaxel weakly-alkaline derivative, preparation, and synthesis thereof, a liposome preparation containing the cabazitaxel weakly-alkaline derivative and application of the cabazitaxel weakly-alkaline derivative in a drug delivery system are provided. Cabazitaxel is connected with a weakly-alkaline intermediate through an ester bond, the ester bond can be broken under the action of esterase in vivo, and an active drug is released. A connecting group is C1-C4 alkyl, C3-C6 naphthenic base or phenyl; [N] is an N-methyl piperazinyl group, a piperidinyl group, a 4-(1-piperidinyl) piperidinyl group, a morpholinyl group, a pyrrolidine group or other tertiary amine structures. The cabazitaxel weakly-alkaline derivative can be prepared into the liposome preparation having high drug loading capacity, high encapsulation efficiency, and good stability.

Abstract: A pharmaceutical composition containing a tyrosine kinase activity inhibitor as an active ingredient may increase the expression of sodium iodide symporter in thyroid cancer cells, thereby promoting iodine uptake and killing thyroid cancer cells. Thus, the composition may he useful for the treatment of thyroid cancer.

Abstract: A compound comprising a first ligand LA, where LA comprises a structure of Formula I, is provided. In Formula I, each of X1, X2, X3, and X4 represents CR, CRR?, NR, or N; Y is selected from a linking group; each of R, R?, R?, R1, R1?, R2, R2?, R3, R3?, R4, and R4? is hydrogen or a substituent; each represents a single bond or a double bond; any two adjacent substituents may be joined or fused to form a ring; two adjacent ones of R1, R2, R3, and R4 are joined together to form a fused 5-membered heterocyclic ring, Ring A, while the remaining two of R1, R2, R3, and R4 cannot be joined to form an aromatic ring; and Ring A is joined to a metal M by a direct bond. Formulations, OLEDs, and consumer products comprising the compound are also provided.

Abstract: A system and a method for Alzheimer's disease prediction using a neural network, a computer-readable recording medium with a stored program, and a computer program product are provided. The processor obtains a first brain MRI data, a second brain MRI data, a first neuropsychological assessment score, and a second neuropsychological assessment score. The processor obtains a plurality of image feature data according to the first brain MRI data and the second brain MRI data. Each image feature data is selected from a group consisting of a plurality of hippocampal subfield geometric change data. The processor obtains a neuropsychological change data according to the first neuropsychological assessment score and the second neuropsychological assessment score. The processor obtains an Alzheimer's disease prediction result according to the neural network module, the image feature data, and the neuropsychological change data.

Abstract: Provided are peptides that based on the amino acid sequences LDPAKDCGDQKYAY (SEQ ID NO: 1) and LDPSKDCGDPKYAY (SEQ ID NO: 2), optionally wherein the peptide includes an N-terminal stearate modification. Also provided are method for using the disclosed peptides for inhibiting neointima formation in mammals, methods for inhibiting division and/or proliferation of vascular smooth muscle cells, and uses of the disclosed peptides for treating cardiovascular diseases and/or disorder associated with undesirable vascular SMC proliferation, which in some embodiments can re-late to inhibiting neointima formation in a mammal.

Abstract: A method for super-resolution photoacoustic microscopy of an object. The method includes optically exciting the object according to a plurality of excitation patterns utilizing a digital micromirror device (DMD), receiving a plurality of acoustic waves propagated from the object due to optically exciting the object, reconstructing each of a plurality of photoacoustic (PA) images from a respective acoustic wave of the plurality of acoustic waves, and obtaining a super-resolution PA image of the object from the plurality of PA images by applying a frequency domain reconstruction method to the plurality of PA images. Each of the plurality of acoustic waves are associated with a respective excitation pattern of the plurality of excitation patterns.

Abstract: Systems and methods to selectively protect therapeutic cells by reducing CD33 expression in the therapeutic cells using base editors and targeting non-therapeutic cells with an anti-CD33 therapy are described. The selective protection results in the enrichment of the therapeutic cells while simultaneously targeting any diseased, malignant and/or non-therapeutic CD33 expressing cells within a subject.

Abstract: Compositions, systems and methods for delivering CRISPR/Cas9-based genome editing system to a cell.

Abstract: According to various embodiments, a machine learning based method, system, and non-transitory computer-readable medium for identifying content on social media related to one or more coordinated influence efforts are disclosed. The method includes generating one or more datasets of post-uniform resource locator (URL) pairs produced from one or more known coordinated influence efforts on one or more social media platforms. The method further includes generating one or more datasets of post-URL pairs produced from one or more random users on one or more social media platforms. The method additionally includes extracting a plurality of content-based features from the post-URL pairs from known coordinated influence efforts and random users.