Abstract: A flexible wire comprises a conductive core surrounded by one or more radial p-n diodes and alternating conductive and non-conductive bands along an outermost surface. Methods for producing the wire are also disclosed, as are textiles and other flexible materials comprising or consisting of such flexible wires.

Abstract: Described herein is a genetic modifier of cystic fibrosis (CF), which may serve as a predictor of the efficacy of a CFTR-directed therapy. SNPs rs7512462 or rs2869027 in non-coding regions of SLC26A9 are shown to correlate with CF lung disease severity in patients having CFTR mutations that leave protein at the cell surface, e.g. gating mutations such as G551D. It is also shown that patient response to Ivacaftor correlates with SLC26A9 genotype. Given the biology of SLC26A9, risk alleles of SLC26A9 should correlate with reduced SLC26A9. SLC26A9 activity (marked by e.g. genotype or expression level) is therefore a predictor of treatment efficacy for any CFTR-directed therapeutic, such as Ivacaftor or Lumacaftor. Associated methods of selecting and treating patients are described, along with related kits, uses, and drug discovery platforms.

Abstract: The present disclosure discloses an antimicrobial peptide Scyreprocin of Scylla paramamosain and a method thereof, wherein an amino acid sequence of the antimicrobial peptide Scyreprocin comprises a sequence shown in SEQ ID NO 01, and the antimicrobial peptide is expressed and purified by using genetic engineering technology. The recombinant antimicrobial peptide Scyreprocin has advantages of wide antimicrobial spectrum, good antimicrobial effect, and rapid germicidal rate, shows great application significance, and has good application in preparation of antimicrobial agents. The recombinant antimicrobial peptide Scyreprocin has no cytotoxicity to mouse hepatocytes AML12, human liver cells L02, and can be safely used for medical treatment or can be used as a feed composition.

Abstract: An improved method of performing object segmentation and classification that reduces the memory required to perform these tasks, while increasing predictive accuracy. The improved method utilizes a capsule network with dynamic routing. Capsule networks allow for the preservation of information about the input by replacing max-pooling layers with convolutional strides and dynamic routing, allowing for the reconstruction of an input image from output capsule vectors. The present invention expands the use of capsule networks to the task of object segmentation and medical image-based cancer diagnosis for the first time in the literature; extends the idea of convolutional capsules with locally-connected routing and propose the concept of deconvolutional capsules; extends the masked reconstruction to reconstruct the positive input class; and proposes a capsule-based pooling operation for diagnosis.

Abstract: An automatic feeding device and method for a seedling bed of a transplanter, comprising: a bracket installed on the transplanter; several trays, obliquely arranged on the bracket downwards, and the bottom of the trays being provided with release mechanisms for releasing the rice seedling bed; a conveyor belt, arranged on the bracket; a photoelectric sensor, arranged on the transplanting platform; and a controller, in communication connection with the photoelectric sensor, when the photoelectric sensor detects that the height of the remaining rice seedling bed on the transplanting platform is lower than the height of the photoelectric sensor. Only one driver is needed to operate, so that the labor input is greatly reduced, and the labor intensity is reduced; meanwhile, the space is saved by the reduction of the number of workers, enabling more seedling raw materials to be stored.

Abstract: Many mobile devices are used for documenting different scenarios that are encountered by the users as they go about their daily lives. In many situations, a mobile device may be used to document the scenario. This data may be of significant forensic interest to an investigator. In many situations, the owner of the phone may be willing to provide the investigator access to this data (through a documented consent agreement). Such consent is usually contingent upon the fact that not all the data available on the phone may be extracted for analysis, either due to privacy concerns or due to personal reasons. Courts have also opined in several cases that investigators must limit data extracted, so as to focus on only “relevant information” for the investigation at hand. Thus, only selective (or filtered) data should be extracted as per the consent available from the witness/victim (user). Described herein is the design and implementation of such a targeted data extraction system (TDES) for mobile devices.

Abstract: The present disclosure is a method for managing capabilities of network security functions (NSF) by a security controller in a security management system.

Abstract: A system useful for performing ultrasound elastography of organs such as the liver allows efficient and robust data acquisition. The system may be applied to perform real-time, noninvasive ultrasound imaging of the liver in humans. Steady-state, shear wave absolute elastography is used to measure the Young's modulus of the liver tissue. This method involves the use of an external exciter or vibrator to shake the tissue and generate a shear wave. Accurate placement of an ultrasound transducer facilitates measurement of the tissue motion due to the shear wave. The stiffness of tissues in the region being imaged may be computed from the measured tissue motions. The following innovations address both vibrator and transducer placement, as well as some specific methods to ensure adequate wave propagation, in order to obtain accurate and consistent measurements.

Abstract: The projection image compensating method according to an embodiment of the present disclosure includes acquiring mesh data, at least one representative image, at least one supplementary image, and position information which is information about an obtaining pose of each image for an indoor space; adding an index of each of the plurality of faces to a matrix corresponding to a size of the at least one representative image in accordance with a result of projecting the plurality of faces which configures the mesh data to the at least one representative image; detecting at least one occluded face among the plurality of faces, using an index added to the matrix; and extracting pixel information which is information of a pixel value corresponding to the at least one occluded face from the at least one supplementary image.

Abstract: Provided herein are nanoparticle-lipid composite carriers as theranostic agents, particularly for diagnosis and/or treatment of cancers and related diseases and conditions. In particular embodiments, the carrier composites comprise a lipid core and an outer shell of functionalized nanoparticles (fNPs).

Abstract: A compound of Formula I: wherein Y is O, S, or Se; wherein each X1-X14 is independently C or N; wherein two consecutive X1-X14 in the same ring are not N; wherein any of X1-X14 is C when it forms a direct bond to RA, RB, RC, or RD; wherein RA, RB, RC, and RD each independently represent mono to the maximum allowable substitution, or no substitution; wherein each RA, RB, RC, and RD is independently a hydrogen or a substituent selected from the group consisting of deuterium, halogen, alkyl, cycloalkyl, heteroalkyl, heterocycloalkyl, arylalkyl, alkoxy, aryloxy, amino, silyl, alkenyl, cycloalkenyl, heteroalkenyl, alkynyl, aryl, heteroaryl, acyl, carboxylic acid, ether, ester, nitrile, isonitrile, sulfanyl, sulfinyl, sulfonyl, phosphino, and combinations thereof; wherein RD represents mono to the maximum allowable substitution at least one RD is not hydrogen; and wherein any two substituents are optionally joined or fused together to form a ring.

Abstract: There are provided a reactivity-introduced compound that imparts reactivity capable of bonding of a solid to another material, can perform imparting to a solid with high efficiency, and has high adhesion of bonding, a manufacturing method thereof, a surface-reactive solid using the same, and a manufacturing method of a surface-reactive solid. There are provided a reactivity-introduced compound provided on a surface of the solid for bonding the solid to another material, the reactivity-introduced compound including a triazine ring, an alkoxysilyl group (including a case where an alkoxy group in the alkoxysilyl group is OH), and a diazomethyl group in one molecule, a manufacturing method thereof, a surface-reactive solid using the same, and a manufacturing method of a surface-reactive solid.

Abstract: Compositions and methods disclosed herein can help provide improved delivery of non-natural therapeutic nucleotides for the treatment of diseases such as cancer. An example composition includes an assembly of amphiphilic polynucleotides, where each amphiphilic polynucleotide includes an aptamer portion, a first nucleotide portion, and a second nucleotide portion.

Abstract: Temporal variations in one or more characteristics measured from a cell-free DNA sample are used to estimate a gestational age of a fetus. Example characteristics include the methylation level measured from the cell-free DNA sample, size of DNA fragments measured from the cell-free DNA sample (e.g., proportion of fetal-derived DNA fragments longer than a specified size), and ending patterns of the DNA fragments align to a reference genome.

Abstract: In an embodiment, the invention provides a method and reagents for detection of ?-herpesvirus circRNA. In another embodiment, the invention provides a method and reagents for detection of EBV circRNA. In still another embodiment, the invention provides a method and reagents for detection of KSHV circRNA. The method can be expanded to other herpesviruses and even non-herpesviruses that generate circRNA upon cellular infection.

Abstract: The subject invention pertains to compositions and methods for preparing and using recombinant proteins based on the fungal Coprinus comatus Y3 protein to control plant and animal viruses and microbes, and diagnose, prevent and treat cancers. Methods are disclosed using compositions comprising recombinant Y3 proteins to diagnose, prevent and/or treat cancer diseases based on recombinant Y3 protein interaction with glycans expressed on cancer cells.

Abstract: Disclosed is a preparation method of an all-weather self-healing stretchable conductive material, which uses acrylic acid and modified polyglutamic acid as a substrate, adds Fe3+ to form coordination, adjusts the volume ratio of water and glycerin, and heats to generate radical polymerization, so as to obtain a uniform double-layer three-dimensional network structure. The obtained polyacrylic acid and polyglutamic acid composite hydrogel has good mechanical properties and characteristics of rapid self-healing. A composite carbon film is prepared by depositing a metal layer of 20 nm to 80 nm thick on a single-layer aligned carbon film by magnetron sputtering, and then the composite hydrogel is adhered to each of the upper and lower sides of the composite carbon film respectively to form an all-weather self-healing stretchable conductive material of a sandwich structure.

Abstract: A query suggestion to expand an initial query is calculated whereby the cost of the expanded initial query is bounded in both time and quality. The user validates a subset of the top-n answers Q(G) to a query Q and provides adjusted configuration parameters. The top-n diversified ?-expansion terms Q? are calculated from the validated subset of answers Q(G) to the query Q and are provided to an interactive user interface for selection. Answers Q?(G) for the top-n diversified ?-expansion terms Q? are cost bounded by cost threshold ? and exploration range r specified by the user. The user selects a new term of terms Q? and an incremental query evaluation of the new term is invoked to compute expanded query answers Q?(G) by incrementally updating the validated subset of answers Q(G), without re-evaluating an expanded query Q? including the new term from scratch.

Abstract: Improved manufacturing processes and resulting anisotropic permanent magnets, such as for example alnico permanent magnets, having highly controlled and aligned microstructure in the solid state are provided. A certain process embodiment involves applying a particular orientation and strength of magnetic field to loose, binder-coated magnet alloy powder particles in a compact-forming device as they are being formed into a compact in order to preferentially align the magnet alloy powder particles in the compact. The preferential alignment of the magnet alloy powder particle is locked in place in the compact by the binder after compact forming is complete. After removal from the device, the compact can be subjected to a subsequent sintering or other heat treating operation.

Abstract: Carbon fiber composites containing lignin carbon fibers are described. The lignin carbon fibers can be derived from organosolv lignin obtained from single source lignocellulosic feedstocks or combinations of such feedstocks or lignin obtained via other pulping or extraction methods. Also described are methods of preparing the carbon fiber composites.