Abstract: The present invention includes composition and methods for composition for the oral delivery of a therapeutic agent that reduces, desensitizes, or prevents food, respiratory and other allergies. First pollen is cleaned to remove naturally-occurring allergic plant proteins to form a cleaned pollen and a therapeutically effective amount of an allergen is introduced into the cleaned pollen. The allergen-loaded cleaned pollen is delivered to a subject in need of therapy.

Abstract: A fruit wine aroma enhancement brewing technology using cutinase belongs to the technical field of fruit wine brewing. According to the present disclosure, in order to solve the problem that fruit wine prepared through an existing fruit wine fermentation technology is poor in quality such as aroma and taste, Muscat grapes or apples are adopted as raw materials, and after crushing, separating peel residue, performing peel residue heat treatment and enzyme treatment, mixing the treated peel residue and clear juice, adding auxiliary materials (potassium metabisulfite, pectinase and ?-glucosidase), adjusting a sugar degree, inoculating a high-glycerol-field yeast and fermenting with temperature controlled, inoculating an active dry yeast and fermenting with the temperature controlled until fermentation is finished, separating and removing the peel residue, fining, filtering to remove residue, performing stabilizing treatment and performing filtration sterilization, dry grape wine or cider is obtained.

Abstract: The present invention addresses the problem of providing an endocytosis enhancer comprising associates formed from a fluorescent protein. The fluorescent protein is preferably any one selected from the group consisting of a white fluorescent protein, a red fluorescent protein, a yellow fluorescent protein, a blue fluorescent protein and a green fluorescent protein. The endocytosis enhancer according to the present invention can enhance the cellular uptake of a drug, which is encapsulated in micelles each formed from a fluorescent-protein-supported carbosilane dendrimer, through endocytosis.

Abstract: The techniques described herein may provide an efficient and secure two-party distributed signing protocol for the identity-based signature scheme described in the IEEE P1363 standard. For example, in an embodiment, a method may comprise generating a distributed cryptographic key at a key generation center and a first other device and a second other device and generating a distributed cryptographic signature at the first other device using the second other device.

Abstract: Described herein are compounds of the formula (I), as well as pharmaceutical compositions comprising such compounds, and methods for using such compounds/pharmaceutical compositions for treating neurodegenerative diseases including Alzheimer's disease, Parkinson's disease, Huntington's disease, and multiple sclerosis (MS).

Abstract: A flexible wire comprises a conductive core surrounded by one or more radial p-n diodes and alternating conductive and non-conductive bands along an outermost surface. Methods for producing the wire are also disclosed, as are textiles and other flexible materials comprising or consisting of such flexible wires.

Abstract: A device for measuring strain on the exterior of a pipe includes a body comprising a top portion and a bottom portion; one or more elastically deformable members coupled between the top portion and the bottom portion, wherein each of the one or more elastically deformable members have an outer contact surface and an inner non-contact surface. One or more sensors are disposed on the inner non-contact surface of one or more of the elastically deformable members. The sensors, during use, provide data that can be used to determine changes in strain on the exterior of the pipe. In another embodiment, one or more sensors are embedded in, or attached to, a casing disposed in a wellbore. In an embodiment, a method includes pressurizing or depressurizing the wellbore with a fluid and measuring the strain induced in the casing (or in an open wellbore) in response to this change in wellbore pressure.

Abstract: Improved manufacturing processes and resulting anisotropic permanent magnets, such as for example alnico permanent magnets, having highly controlled and aligned microstructure in the solid state are provided. A certain process embodiment involves applying a particular orientation and strength of magnetic field to loose, binder-coated magnet alloy powder particles in a compact-forming device as they are being formed into a compact in order to preferentially align the magnet alloy powder particles in the compact. The preferential alignment of the magnet alloy powder particle is locked in place in the compact by the binder after compact forming is complete. After removal from the device, the compact can be subjected to a subsequent sintering or other heat treating operation.

Abstract: The present disclosure provides azetidine compounds of Formula I and their pharmaceutically acceptable salts, their compositions, and methods for their use in determining azetidine compound binding to proteins. The azetidine compounds are useful as probes, for monitoring diacylglycerol kinase activity, and for identifying druggable targets.

Abstract: Carbon fiber composites containing lignin carbon fibers are described. The lignin carbon fibers can be derived from organosolv lignin obtained from single source lignocellulosic feedstocks or combinations of such feedstocks or lignin obtained via other pulping or extraction methods. Also described are methods of preparing the carbon fiber composites.

Abstract: The present disclosure relates generally to antioxidants. More particularly, the present disclosure relates to lubricating compositions comprising an antioxidant.

Abstract: Embodiments of the present invention provide a method and apparatus for accelerating distributed training of a deep neural network. The method comprises: based on parallel training, the training of deep neural network is designed as a distributed training mode. A deep neural network to be trained is divided into multiple sub-networks. A set of training samples is divided into multiple subsets of samples. The training of the deep neural network to be trained is performed with the multiple subsets of samples based on a distributed cluster architecture and a preset scheduling method. The multiple sub-networks are simultaneously trained so as to fulfill the distributed training of the deep neural network. The utilization of the distributed cluster architecture and the preset scheduling method may reduce, through data localization, the effect of network delay on the sub-networks under distributed training; adapt the training strategy in real time; and synchronize the sub-networks trained in parallel.

Abstract: The present invention discloses a shaft-tube joint structure of a carbon fiber reinforced plastic (CFRP) drive shaft. The shaft-tube joint structure includes a hollow shaft tube, a plurality of first rectangular teeth being uniformly and circumferentially arranged at both ends of the hollow shaft tube; two shaft-tube joints which are respectively fixed at two ends of the hollow shaft tube, the thickness of the shaft-tube joint being smaller than that of the hollow shaft tube, and an inner wall of the shaft-tube joint being smoothly connected to an inner wall of the hollow shaft tube; and a universal joint, an end thereof being tubular, a plurality of second rectangular teeth being uniformly and circumferentially arranged, the universal joint being matched with and sleeving the outer wall of the shaft-tube joint, and the second rectangular teeth being meshed with the first rectangular teeth.

Abstract: A biofilm disrupting composition for use on chronic wounds comprising (i) at least one biologically acceptable thiol based antioxidant (ii) at least one biofilm disruptor and (iii) at least one biocide. Also disclosed is a process of preparing the composition. Also disclosed is the use of the composition for the manufacture of a medicament for the treatment of a chronic wound, and a method of treating a chronic wound in a patient comprising administering the biofilm disrupting composition.

Abstract: Methods and compositions that provide an environment that promotes enhanced protein expression and/or folding are provided. More particularly, engineered thermostable ferritin assemblies capable of encapsulating polypeptides, nucleic acids or small molecules, which includes a modified ferritin subunit which lacks an unstructured carboxy-terminal sequence are provided. Methods and compositions for delivery of protein therapeutics are also provided.

Abstract: The present disclosure provides a tidal simulation test device and a method of use thereof. The tidal simulation test device includes a water supply pool, a water level adjustment pool, a subtidal zone simulation pool, an intertidal zone simulation pool, a supratidal zone simulation pool and a two-way water flow adjustment control box. The two-way water flow adjustment control box is provided therein with an electromagnetic flow control meter, a forward frequency conversion self-priming pump, a reverse frequency conversion self-priming pump and an intelligent time-controlled three-way controller. In the method, the start and stop of the forward frequency conversion self-priming pump and the reverse frequency conversion self-priming pump are controlled through an intelligent switch, and a water flow is adjusted through the electromagnetic flow control meter, thereby realizing periodic changes in a water level to simulate different types of tides and coastal wetlands.

Abstract: An improved method of performing object segmentation and classification that reduces the memory required to perform these tasks, while increasing predictive accuracy. The improved method utilizes a capsule network with dynamic routing. Capsule networks allow for the preservation of information about the input by replacing max-pooling layers with convolutional strides and dynamic routing, allowing for the reconstruction of an input image from output capsule vectors. The present invention expands the use of capsule networks to the task of object segmentation and medical image-based cancer diagnosis for the first time in the literature; extends the idea of convolutional capsules with locally-connected routing and propose the concept of deconvolutional capsules; extends the masked reconstruction to reconstruct the positive input class; and proposes a capsule-based pooling operation for diagnosis.

Abstract: An automatic feeding device and method for a seedling bed of a transplanter, comprising: a bracket installed on the transplanter; several trays, obliquely arranged on the bracket downwards, and the bottom of the trays being provided with release mechanisms for releasing the rice seedling bed; a conveyor belt, arranged on the bracket; a photoelectric sensor, arranged on the transplanting platform; and a controller, in communication connection with the photoelectric sensor, when the photoelectric sensor detects that the height of the remaining rice seedling bed on the transplanting platform is lower than the height of the photoelectric sensor. Only one driver is needed to operate, so that the labor input is greatly reduced, and the labor intensity is reduced; meanwhile, the space is saved by the reduction of the number of workers, enabling more seedling raw materials to be stored.

Abstract: Doped nitride-based semiconductor materials and methods of producing these materials are described herein.

Abstract: The description provides a molecular switch comprising at least two nanoparticles, wherein a first nanoparticle comprises DNA and/or RNA oligonucleotides, and a second nanoparticle which is complementary to the first nanoparticle comprises reverse complementary DNA and/or RNA oligonucleotides of the first nanoparticle; wherein the complementary nanoparticles interact under physiological conditions leading to thermodynamically driven conformational changes in the first and second nanoparticles leading to their re-association to release one or more duplexes comprising said DNA and/or RNA oligonucleotides and the reverse complementary DNA and/or RNA oligonucleotides, and wherein the nanoparticles are not rings and have no single stranded toeholds.