Abstract: The present disclosure relates to a drug combination for treating non-small cell lung cancer, in particular to uses of ergosterol combined with gefitinib, and belongs to the technical field of biomedicine. In the present disclosure, the mechanism of action that ergosterol (ERG) combined with gefitinib (GEF) induces apoptosis of non-small cell lung cancer (NSCLC) cells is firstly studied; then an RGG cyclic peptide/R8 peptide modified ERG combined with GEF active drug-loaded targeted liposome delivery system (RGD/R8-ERG/GEF-LIP) is constructed; and the RGD/R8-ERG/GEF-LIP is prepared into a freeze-dried powder to improve stability, quality evaluation and preliminary evaluation of in vitro anti-lung cancer effects are conducted, and a nude mouse lung cancer xenograft model is established for conducting preliminary pharmacodynamic research and in vivo targeting research.

Abstract: To provide a volume-type optical element in which a self-cloning photonic crystal is used. An optical element is provided with half-wave plates of photonic crystals formed on the xy plane and laminated in the z-axis direction in a three-dimensional space x, y, z. The groove direction of the photonic crystals is a curved line, and the angle in relation to the y-axis direction changes continuously in the range of 0°-180°. Light entering the optical element in the axial direction is emitted from the optical element upon being divided and converted into clockwise circularly polarized light in the direction facing the x-axis by a given angle from the z-axis and anticlockwise circularly polarized light in the direction facing the ?x-axis by a given angle from the z-axis. Laminating or placing a quarter-wave plate comprising a photonic crystal on one or both surfaces makes it possible to divide light entering from the z-axis direction of the optical element into two orthogonal linearly polarized lights.

Abstract: Disclosed is a molecular imaging method for evaluating liver regeneration ability after ALPPS. The method includes steps of: 1) preparing a VX2 rabbit liver cancer model; 2) performing ALPPS for the VX2 rabbit liver cancer model; 3) synthesizing 18F-Fluoromethylcholine (18F-Methylcholine, 18F-FCH); 4) PET/CT imaging and data processing for 18F-FCH. The disclosure is the first to propose the use of 18F-FCH PET/CT to monitor the proliferative capacity of residual liver, and further indirectly reflect the increased ability of cell membrane synthesis on the basis that 18F-FCH has higher choline metabolism in residual liver tissue, so that the liver regeneration ability after ALPPS is evaluated by the molecular imaging method, thereby providing important new ideas for the clinical selection of ALPPS to choose the best time for second-stage surgery.

Abstract: An adjustable and self-locking fixation device for fixedly securing two structures wherein the device comprises two spans and a receiving aperture configured to receive the spans and form a closed loop around a first structure. The two spans are further configured to secure and lock onto each other so as to form a second closed loop around the two structures and secure the two structures in a tensioned state.

Abstract: The present invention relates to a carbon nanotube-transition metal oxide composite and a method for making the composite. The composite comprises at least one carbon nanotube and a plurality of transition metal oxide nanoparticles. The plurality of transition metal oxide nanoparticles are chemically bonded to the at least one carbon nanotube through carbon-oxygen-metal (C—O-M) linkages, wherein the metal is a transition metal element. The method for making the composite comprising the following steps: step 1, providing at least one carbon nanotube obtained from a super-aligned carbon nanotube array; step 2, pre-oxidizing the at least one carbon nanotube; step 3, dispersing the at least one carbon nanotube in a solvent to form a first suspension; step 4, dispersing a material containing transition metal oxyacid radicals in the first suspension to form a second suspension; and step 5, removing the solvent from the second suspension and drying the second suspension.

Abstract: The invention relates to a drug delivery device adapted for carrying and delivering both hydrophilic and lipophilic drug molecules. The drug delivery device includes a porous body for adsorption of drug molecules, the body including a plurality of microspheres, and a hydrogel forming cross-links connecting the plurality of microspheres.

Abstract: Disclosed is a method of carbon-coating a secondary battery active material and a second battery active material produced by the method. The method of producing a carbon-coated battery active material involves mixing a carbon precursor with liquid carbon dioxide to produce a coating solution comprising a carbon material, coating a battery active material with the carbon material by applying the coating solution to the battery active material, and sintering the coated battery active material to obtain the carbon-coated battery active material.

Abstract: Catalyst compositions for the conversion of aldehyde compounds and primary alcohol compounds to olefins are disclosed herein. Reactions include oxidative dehydroxymethylation processes and oxidative dehydroformylation methods, which are beneficially conducted in the presence of a sacrificial acceptor of H2 gas, such as N,N-dimethylacrylamide.

Abstract: Provided herein are methods of detecting target analytes, such as nucleic acids, for example microRNAs using an enhanced Tyramide Signal Amplification (TSA) method that employs probes tagged with tyramide-binding groups to amplify the effects of the TSA. The accessibility of the tyramide-binding groups, such as hydroxyphenyl groups, provides for large improvements in signal due to faster reaction with the radicals. The present invention further includes the application of the assay for detecting specific microRNAs.

Abstract: Embodiments of the present invention provide a motion compensating prediction method and a motion compensating prediction apparatus. The motion compensating prediction method includes: determining a location of an initial reference pixel of a current pixel in a reference image, where the current pixel is located in a first sub-image of a current image; when the initial reference pixel is located outside a second sub-image that is in the reference image and that is at a location corresponding to the first sub-image, determining a location of a target reference pixel of the current pixel in the reference image based on the location of the initial reference pixel; and determining a predicted value of a pixel value of the current pixel based on a pixel value of the target reference pixel and/or a pixel value of a pixel near the target reference pixel.

Abstract: Methods for simultaneously forming two or more different colored material layers on a substrate. include performing surface energy patterning (SEP) to define a first, hydrophobic region and a second, hydrophilic region on the substrate, applying first and second materials on the second region, wherein the first material comprises a material having a first color, and wherein the second material comprises a material having a second color, and doctor blade coating the first and second materials simultaneously to form first and second material layers on the substrate. The methods are particularly useful for making multi-color light emitting and detecting components such as LEDs and OPDs.

Abstract: In various embodiments, methods are provided for applying transcutaneous and/or epidural spinal cord stimulation with and without selective pharmaceuticals to restore voluntary control of hand function in tetraplegic subjects.

Abstract: The disclosure is directed to nucleic acid, host cell, and polypeptide compositions encoded by the unicellular green alga Chromochloris zofingiensis, methods of making such compositions, and method of using the compositions to produce astaxanthin.

Abstract: A self-capacitance based remote power delivery device includes a modulating power source electrically coupled to a grounded substrate, an energy harvesting device coupled to the grounded substrate, and the substrate. The modulating power source is configured to be capacitively coupled to a self-capacitive body. The energy harvesting device configured to be capacitively coupled to the self-capacitive body, and the substrate is configured to be capacitively coupled to a portion of the self-capacitive body in direct contact with the substrate.

Abstract: The present invention relates to compositions and methods for modulating coagulation through modulating the level or activity of ENPP4.

Abstract: Various embodiments for system and method of adaptive lighting for data-driven non-line-of-sight imaging are disclosed.

Abstract: A method is disclosed for phase contrast magnetic resonance imaging (MRI) comprising: acquiring phase contrast 3D spatiotemporal MRI image data; inputing the 3D spatiotemporal MRI image data to a three-dimensional spatiotemporal convolutional neural network to produce a phase unwrapping estimate; generating from the phase unwrapping estimate an integer number of wraps per pixel; and combining the integer number of wraps per pixel with the phase contrast 3D spatiotemporal MRI image data to produce final output.

Abstract: Embodiments of a system and methods for detecting social media designed to spread malicious information to “viral” proportions are disclosed. Historical cascade event data from preselected social media accounts as well as information from related accounts is applied to one or more causality metrics to generate a set of causality values. Causality values are further refined and analyzed to determine how casual a user is with respect to a cascade as opposed to other similar users.

Abstract: Provided is an electronic signature technique depending on a diametrically different algorithm from the existing asymmetric key infrastructure electronic signature technique which generates predetermined syndrome data based on a message to be transmitted a data receiving device and then detects an error vector for an electronic signature from the syndrome data by using a parity check matrix and then generates an electronic signature value based on an error vector for the electronic signature and transmits the generated electronic signature value to the data receiving device.

Abstract: Bacterial strains are provided that can be isolated from the microflora of lowbush blueberry (Vaccinium angustifolium), and that are capable of increasing the antioxidant content of their growth medium. The bacteria can be used, for example, to increase the antioxidant content of various foodstuffs, as probiotics or as additives to animal feed. Antioxidant-enriched compositions produced by fermentation processes utilising the bacteria are also provided. The antioxidant-enriched compositions can be used in the preparation of cosmetics and nutritional supplements. The antioxidant-enriched compositions also have therapeutic applications.