Abstract: The invention is directed to a composition that safely removes a cured dental cement or resin from metal brackets, metal braces, and enamel surfaces of teeth. It contains eugenol, isoeugenol, methyl-eugenol or an isomer thereof. A method for removing orthodontic fixtures adhered with a dental cement or resin to the enamel surfaces of teeth from these surfaces by contacting the dental cement or resin with a composition containing eugenol.
Type:
Grant
Filed:
April 15, 2021
Date of Patent:
October 12, 2021
Assignee:
King Abdulaziz University
Inventors:
Ahmed Samir Ibrahim Bakry, Mona Aly Abbassy, Amal Linjawi, Ali Habib Hassan, Ahmed Fathy Hanafy, Gihan Salah Labib, Amal Mohammed S Abushal
Abstract: Compositions and methods for reducing the level of nornicotine and N?-nitrosonornicotine (NNN) in Nicotiana plants and plant parts thereof are provided. The compositions comprise isolated polynucleotides and polypeptides for cytochrome P450s that are involved in the metabolic conversion of nicotine to nornicotine in these plants. Expression cassettes, vectors, plants, and plant parts thereof comprising inhibitory sequences that target expression or function of the disclosed cytochrome P450 polypeptides are also provided. Methods for the use of these novel sequences to inhibit expression or function of cytochrome P450 polypeptides involved in this metabolic conversion are also provided. The methods find use in the production of tobacco products that have reduced levels of nornicotine and its carcinogenic metabolite, NNN, and thus reduced carcinogenic potential for individuals consuming these tobacco products or exposed to secondary smoke derived from these products.
Type:
Grant
Filed:
July 15, 2019
Date of Patent:
October 12, 2021
Assignees:
North Carolina State University, University of Kentucky Research Foundation
Inventors:
Ralph E. Dewey, Balazs Siminszky, Steven W. Bowen, Lily Gavilano
Abstract: Disclosed is a texture presentation apparatus driven by a high-density flexible electromagnetic coil array, including a surface layer and a driving layer. The surface layer is in direct contact with the fingertip of a finger to ensure interaction safety of a user, is capable of adjusting the friction force when the finger touches and slides on the surface layer, and has a shielding and protection effect on the driving layer; the driving layer includes a stretchable soft substrate and a plurality of micro driving units, each micro driving unit is independently controllable, the driving layer adjusts the microscopic geometric morphology of a texture surface; the texture presentation apparatus is capable of implementing multi-scale fine texture presentation; when the fingertip comes into contact with the surface layer, the texture presentation apparatus controls, based on different surface textures of an object to be simulated in a virtual environment.
Abstract: Disclosed are substituted heterocycle compounds including substituted pyrazoles, substituted pyrimidines, and substitute triazoles. The substituted heterocycles disclosed herein are shown to be useful in inhibiting c-MYC and may be utilized as therapeutics for treating cancer and cell proliferative disorders.
Type:
Grant
Filed:
August 31, 2018
Date of Patent:
October 12, 2021
Assignee:
Northwestern University
Inventors:
Gary E. Schiltz, Rama K. Mishra, Huiying Han, Sarki A. Abdulkadir, Javier Izquierdo-Ferrer, Atul D. Jain
Abstract: The present disclosure belongs to the technical field of sensors, relates to a graphene resonant gas sensor, and in particular, to a graphene resonant gas sensor based on doped metal atoms and a preparation process therefor. In the present disclosure, the metal atoms are embedded in a graphene resonant beam, and a transition metal layer may use the doped metal atoms as anchor points to be tightly adsorbed to the surface of the graphene resonant beam, so that the quality of surface contact between the transition metal layer and the graphene resonant beam is improved, and the problems such as low quality and low sensitivity of conventional resonant gas sensors are effectively solved.
Abstract: A method and circuit for operating a liquid crystal device, LCD, based polarisation rotator. The method comprises the steps of tracking a capacitance value of the LCD rotator; and controlling a driver setting to the LCD rotator based on the tracked capacitance value to achieve temperature independent operation.
Type:
Grant
Filed:
April 10, 2018
Date of Patent:
October 12, 2021
Assignee:
National University of Singapore
Inventors:
Euk Jin Alexander Ling, Rakhitha Chandrasekara, Kadir Durak
Abstract: A method for spectrum sensing for cognitive radio includes performing a process of local spectrum sensing using receive beamforming and energy detection at each of a plurality of secondary users included in a cognitive radio network, wherein the process of local spectrum sensing decides between two hypotheses corresponding to absence and presence of a primary user, the two hypotheses being formulated using a primary user signal, a plurality of co-channel interferences, and sensing noise, the primary user signal, the plurality of co-channel interferences, and the sensing noise being received at each of the plurality of secondary users, and a set of beamforming weights of the receive beamforming is determined by optimizing a probability of detection and constraining a probability of false alarm.
Type:
Grant
Filed:
April 21, 2021
Date of Patent:
October 12, 2021
Assignee:
King Abdulaziz University
Inventors:
Muhammed Moinuddin, Ubaid M. Al-Saggaf, Mohammed A. Alrefaei, Jawwad Ahmad
Abstract: The invention provides a method of regulating U1 activity associated with its splicing role as well as its role in protecting pre-mRNAs from premature termination by cleavage and polyadenylation, thereby modulating expression of a gene or genes. In one embodiment, the invention includes compositions and methods for regulating gene expression and treating diseases associated with dysregulated gene expression.
Type:
Grant
Filed:
July 5, 2013
Date of Patent:
October 12, 2021
Assignee:
The Trustees of the University of Pennsylvania
Inventors:
Gideon Dreyfuss, Lili Wan, Jung Min Oh, Anna Maria Pinto, Ihab Younis, Michael George Berg, Daisuke Kaida
Abstract: A plant propagation system is described that can be utilized for micropropagation through early stages of plant development. A system can include multiple plant support matrices, containers for the matrices, and optionally a tool for separating sections of a plant support matrix from the remainder of the matrix. During use developing plant tissue can be transferred between matrices and growth media can be varied with little or no damage to developing plant tissue and lower chances for contamination of the developing plant tissues.
Type:
Grant
Filed:
June 2, 2016
Date of Patent:
October 12, 2021
Assignees:
Pioneer Hi-Bred International, Inc., Clemson University Research Foundation
Inventors:
Jeffrey Adelberg, Amber E. Heck, David Dallinger Kurth, Justine M. Olszewski
Abstract: Embodiments include a fiber optic probe comprising an optical fiber, and a sensor component attached to the optical fiber, the sensor component including an asymmetric microlens array imprinted on a stimuli-responsive hydrogel. Embodiments further include a method of fabricating a fiber optic probe comprising depositing a stimuli-responsive hydrogel precursor solution on a substrate mold, the substrate mold including a concave asymmetric microlens array; contacting an end of an optical fiber with the stimuli-responsive hydrogel precursor solution deposited on the substrate mold; and exposing the end of the optical fiber and the stimuli-responsive hydrogel precursor solution to light to form a stimuli-responsive hydrogel sensor imprinted with a convex asymmetric microlens array and attached to the end of the optical fiber. Embodiments further include systems comprising the fiber optic probes.
Type:
Grant
Filed:
April 14, 2020
Date of Patent:
October 12, 2021
Assignees:
Khalifa University of Science and Technology, The University of Birmingham
Abstract: A method for predicting formation permeability by measuring diffusional tortuosity in several directions by pulse gradient NMR. The method comprises evaluating an anisotropic diffusion coefficient by pulsed gradient NMR, determining diffusional tortuosity from the restricted diffusion data, supplementing the NMR results with resistivity and sonic logging data, measuring anisotropic tortuosity and porosity by resistivity and sonic data and combining all components in a single fitting model. The 11-coefficient model is trained to recognize the true values of permeability by comparing the real oil permeabilities measured in a library of oil-carrying rock cores with the NMR, resistivity and sonic correlates. The fitting coefficients are extracted by minimizing the discrepancy between the laboratory measured permeabilities and the predicted values combining all rapid logging information components with the agreement-maximizing weights.
Type:
Grant
Filed:
March 13, 2020
Date of Patent:
October 12, 2021
Assignee:
King Fahd University of Petroleum and Minerals
Abstract: The disclosure herein relates to a method for producing high-quality maltodextrin, and belongs to the technical field of maltodextrin. On the basis of a traditional enzymatic production process of maltodextrin, starch branching enzyme derived from Rhodothermus obamensis is introduced, an ?-1,4-glycosidic bond is cleaved, the cleaved short chain is ligated to a receptor chain to form an ?-1,6-branch point, so the degree of branching is increased and the maltodextrin has more cluster structures. Thereby, the aims that the stability of the maltodextrin is enhanced and the maltodextrin is not easy to retrograde are achieved, and the freeze-thaw stability of the maltodextrin is also improved. The method specifically comprises the steps of slurry preparation, spray liquefaction, starch branching enzyme action, filtration, decolorization, ion exchange, concentration, spray drying, and the like.
Type:
Grant
Filed:
January 20, 2020
Date of Patent:
October 12, 2021
Assignee:
Jiangnan University
Inventors:
Zhaofeng Li, Zhengbiao Gu, Zhe Wang, Caiming Li, Sijia Xu, Li Cheng, Yan Hong
Abstract: A system and methods for the delivery of oxygen through a body cavity of a subject using oxygen microbubbles. Through circulation of oxygen microbubbles through the body cavity, oxygen and carbon dioxide exchange may occur. Overall improvement in extending survival rate time during emergency situations caused by pulmonary or similar oxygen-intake restricting injury and/or failure may be achieved through use of the invented system and methods.
Type:
Grant
Filed:
November 2, 2018
Date of Patent:
October 12, 2021
Assignees:
The Regents of the University of Colorado, a Body Corporate, Board of Regents of the University of Nebraska
Abstract: Power distribution network early failure detection method comprising: a waveform is decomposed into an approximation part and detail parts by wavelet transform, wherein the approximation part is referred to as an approximate shape primitive, and the detail parts are referred to as distortion primitives; the distortion primitives are divided into three primitives including harmonics, pulses and other distortions based on extreme points; characteristics of the primitives and time relationships between the primitives are extracted; probability distribution of the waveform is constructed according to the characteristics of the primitives and the time relationships between the primitives; and a judgment result of the waveform is obtained according to probability distribution of waveforms of different types.
Abstract: The present disclosure provides a method for fabricating a heterogeneous nickel-based catalyst on an aluminum oxide support. The method includes a solution preparation step, a drop-cast step, a first calcining step, and a second calcining step. The solution preparation step is provided for preparing a precursor solution. The drop-cast step is provided for dropping the precursor on the support. The first calcining step is provided for obtaining an oxidation state catalyst. The second calcining step is provided for obtaining the heterogeneous nickel-based catalysts on aluminum oxide support.
Type:
Grant
Filed:
May 9, 2019
Date of Patent:
October 12, 2021
Assignees:
National Tsing Hua University, Chang Chun Plastics Co., Ltd., Chang Chun Petrochemical Co., Ltd., Darien Chemical Corp.
Abstract: An atmosphere-breathing pulsed plasma thruster includes an inlet, a discharge section with an anode in fluid communication with the inlet, and a nozzle in fluid communication with the discharge section. Electrode assemblies extend radially through the discharge section and include a second electrode in the discharge section and an elongate portion extending outwardly. An electrode control mechanism moves the plurality of electrode assemblies between an inner position nearer to the anode and an outer position farther from the anode. At least one igniter extends between the anode and a cathode. An ignition circuit connects the anode and the cathodes to a first source of electric energy, and connects the igniter to a second source of electric energy through a controllable switch. A processor controls the position of the second electrodes, for example, in response to changes in atmospheric pressure.
Type:
Grant
Filed:
July 9, 2019
Date of Patent:
October 12, 2021
Assignee:
University of Washington
Inventors:
Robert M. Winglee, Manuel Azuara Rosales, Corwin Hansen
Abstract: Wnt signaling agonist compositions and methods for their use are provided. Wnt signaling agonists of the invention comprise a frizzled binding moiety, which is fused or conjugated to an LRP5 or LRP6 binding moiety.
Type:
Grant
Filed:
September 11, 2015
Date of Patent:
October 12, 2021
Assignees:
The Board of Trustees of the Leland Stanford Junior University, University of Washington
Inventors:
Kenan Christopher Garcia, David Baker, Claudia Yvonne Janda, Luke Dang, James Daniel Moody
Abstract: The present disclosure is generally related to separators for use in lithium metal batteries, and associated systems and products. Certain embodiments are related to separators that form or are repaired when an electrode is held at a voltage. In some embodiments, an electrochemical cell may comprise an electrolyte that comprises a precursor for the separator.
Type:
Grant
Filed:
April 5, 2017
Date of Patent:
October 12, 2021
Assignees:
Massachusetts Institute of Technology, Carnegie Mellon University, 24M Technologies, Inc.
Inventors:
Yet-Ming Chiang, Venkatasubramanian Viswanathan, Linsen Li, Vikram Pande, Dilip Krishnamurthy, Zeeshan Ahmad, William Henry Woodford
Abstract: A multi-angle spinneret for forming hollow fibers is provided. The multi-angle spinneret includes a body defining a dope chamber, a bore needle channel, and multiple dope channels being oriented at a minimum of two distinct dope channel angles relative to the dope chamber. The body includes a bore needle disposed in the bore needle channel and oriented substantially perpendicular relative to the dope chamber. The bore needle extends though the dope chamber, such that a bore fluid flow through the bore needle is kept separate from a dope flow through the dope channels. A bore fluid outlet is positioned within a dope outlet of the dope chamber, such that a bore fluid flow out of the bore fluid outlet is substantially coaxial with and substantially centered within a dope flow out of the dope outlet.
Type:
Grant
Filed:
March 11, 2021
Date of Patent:
October 12, 2021
Assignee:
King Abdulaziz University
Inventors:
Iqbal Ahmed Moujdin, Rosli Bin Mohd Yunus