Abstract: A pharmaceutical composition and method for treating brain cancer are provided. The method includes administering to a patient in need thereof an effective amount of one or more compounds that include moclobemide, clorgyline, clorgyline's Near-infra-red dye Monoamine Oxidase Inhibitor (NMI), and MHI 148-clorgyline, and their salt thereof. The composition and method are particularly effective in reducing the size of glioblastomas that are temozolomide (TMZ) resistant.
Type:
Grant
Filed:
August 22, 2018
Date of Patent:
February 18, 2020
Assignee:
University of Southern California
Inventors:
Jean C. Shih, Florence M. Hofman, Thomas C. Chen
Abstract: An embodiment includes a system comprising: a substrate of a medical device; an un-foamed polyurethane coating directly contacting the substrate and fixedly attached to the substrate; a thermoset polyurethane shape memory polymer (SMP) foam, having first and second states, which directly contacts the polyurethane coating and fixedly attaches to the polyurethane coating; wherein the polyurethane coating fixedly attaches the SMP foam to the substrate. Other embodiments are described herein.
Type:
Grant
Filed:
July 22, 2016
Date of Patent:
February 18, 2020
Assignee:
The Texas A&M University System
Inventors:
Rachael Muschalek, Keith Hearon, Landon D. Nash, Duncan J. Maitland
Abstract: Various methods for detecting moisture in briefs compatible with high volume manufacturing are disclosed. The embodiments herein facilitate protection of the method of adding moisture sensing to a diaper, but could also be used to add sensing to pads and bandages. The primary design intent is optimal moisture detection and low per unit cost. Electrodes within a garment measure electrical properties of the electrodes to determine if the item has contacted moisture. The target moisture is urine, however, other sources and types of moisture can also be sensed. Additional analysis capabilities can be added by selecting particular electrodes or add materials that may react with chemical components of the moisture. Applications of the research Include monitor of incontinence using smart brief (e.g. diaper); monitor perspiration, bleeding, or failure of the protective garment; and monitoring exposure of an item to moisture, including but not limited to inanimate items.
Type:
Grant
Filed:
September 11, 2018
Date of Patent:
February 18, 2020
Assignees:
BioLink Systems, LLC, University of Louisville Research Foundation, Inc
Inventors:
Ken Heyl, Doug Jackson, John Naber, Roger King
Abstract: Certain embodiments according to the present invention provide sleeve devices suitable for a wide range of therapeutic uses. In accordance with certain embodiments, the therapeutic sleeve device includes a nanofiber fabric assembly, which defines a plurality of pores, and at least one layer of cells embedded in the nanofiber fabric assembly.
Type:
Grant
Filed:
October 7, 2014
Date of Patent:
February 18, 2020
Assignee:
The Johns Hopkins University
Inventors:
Chao-Wei Hwang, Zhiyong Xia, Virginia E. Bogdan, Jeffrey A. Brinker, Gary Gerstenblith, Peter V. Johnston, Steven P. Schulman, Gordon Tomaselli, Robert G. Weiss
Abstract: An aerial vehicle includes a body having a longitudinal axis, a plurality of movable members emanating connected to the body, at least one motor, and at least three aerodynamic propulsors driven by the at least one motor. The movable members are connected to the body and extend away from the body.
Type:
Grant
Filed:
July 27, 2015
Date of Patent:
February 18, 2020
Assignee:
University of Kansas
Inventors:
Ronald M. Barrett, Richard B. Bramlette, Robert B. Honea
Abstract: The present invention provides methods for mineral precipitation and/or cementation of permeable or fractured non-porous materials using isolated urease.
Type:
Grant
Filed:
November 3, 2017
Date of Patent:
February 18, 2020
Assignee:
Arizona Board of Regents on behalf of Arizona State University
Abstract: A method of forming a sintered nickel-titanium-rare earth (Ni—Ti-RE) alloy includes adding one or more powders comprising Ni, Ti, and a rare earth constituent to a powder consolidation unit comprising an electrically conductive die and punch connectable to a power supply. The one or more powders are heated at a ramp rate of about 35° C./min or less to a sintering temperature, and pressure is applied to the powders at the sintering temperature, thereby forming a sintered Ni—Ti-RE alloy.
Abstract: The present invention provides a noise suppression device and equivalent circuit thereof. The noise suppression device comprises a metal plate and at least one first resonance unit. The first resonance unit comprises a plurality of first resonators. Each of the first resonators comprises a first metal segment and at least one first conductive connection segment, the first metal segment is connected to the first conductive connection segment. When the first resonance unit is configured on the metal plate, each of the first metal segments is electrically connected to the metal plate by the corresponding first conductive connection segment. When the resonance of the first resonator occurs, a noise transmitted on the metal plate can be conducted to the first resonator and suppressed by the first resonator.
Abstract: The present invention provides methods and compositions for producing ?-phellandrene hydrocarbons from a photosynthetic microorganism such as cyanobacteria.
Type:
Grant
Filed:
February 5, 2018
Date of Patent:
February 18, 2020
Assignee:
The Regents of the University of California
Inventors:
Anastasios Melis, Fiona K. Davies, Hsu-Ching Chen Wintz, Andreas Zurbriggen
Abstract: A multi-port hybrid-based cancellation network may include a first and second hybrid coupler, and a first and second two-port network. The second hybrid coupler may be distinct from the first hybrid coupler. The first two-port network may include a first filter connected between the first and the second hybrid couplers. The second two-port network may include a second filter that is distinct from but essentially the same as the first filter connected between the first and the second hybrid couplers. Other circuitry components may be connected to one of the ports of multi-port hybrid-based cancellation network. These other circuitry components may have a configuration that increases or maximizes signal isolation between at least two of the ports of the multi-port hybrid-based cancellation network.
Abstract: A compound represented by Chemical Formula 1 according to the present invention can coordinate with metal ions to form a bidirectional or multidirectional metal-organic hybrid structure. Thus, the present invention can synthesize various ligands using amine-aldehyde condensation, and synthesize metal-organic materials using the same.
Type:
Grant
Filed:
July 28, 2017
Date of Patent:
February 18, 2020
Assignees:
LG CHEM, LTD., Seoul National University R&DB Foundation
Inventors:
Dongwhan Lee, Jung Hwan Kim, Won Jong Kwon, Yong Jin Bae
Abstract: Aspects of the present disclosure include fatty acid ?-hydroxyester compounds (e.g., fatty acid esters of ?-hydroxybutyrate), fatty acid esters of butanediol, and pharmaceutically acceptable salts thereof. Also provided are pharmaceutical compositions having one or more fatty acid ?-hydroxyester compounds and/or one or more fatty acid esters of butanediol. Methods for treating a subject by administering one or more esters to the subject are also provided. Kits containing one or more of the subject esters are also described.
Type:
Grant
Filed:
July 29, 2019
Date of Patent:
February 18, 2020
Assignees:
The J. David Gladstone Institutes, The Regents of The University Of California, Ithaca College
Inventors:
Eric Verdin, Scott Michael Ulrich, John C. Newman
Abstract: Provided herein are polymer and metal organic frameworks (MOFs) composites, and methods of use and preparation thereof. In particular, Poly(polyethyleneglycol citrate-co-N-isopropylacrylamide) (PPCN) and copper MOF composites are provided.
Abstract: Provided are a solar cell that can be manufactured by non-vacuum process and can have more excellent photoelectric conversion efficiency and a manufacturing method therefor as well as such a semiconductor device and a manufacturing method therefor. A solar cell, includes at least a first semiconductor layer and a second semiconductor layer. The first semiconductor layer includes metal oxide particles of 1 nm or more and 500 nm or less in average particle size and a compound having relative permittivity of 2 or more and 1,000 or less. For instance, the content of the organic compound in the first semiconductor layer is 10 mass % or more and 90 mass % or less.
Type:
Grant
Filed:
September 4, 2018
Date of Patent:
February 18, 2020
Assignees:
Asahi Kasei Kabushiki Kaisha, Tohoku University
Abstract: The present disclosure provides genetically modified host cells that produce a cannabinoid, a cannabinoid derivative, a cannabinoid precursor, or a cannabinoid precursor derivative. The present disclosure provides methods of synthesizing a cannabinoid, a cannabinoid derivative, a cannabinoid precursor, or a cannabinoid precursor derivative.
Type:
Grant
Filed:
May 10, 2019
Date of Patent:
February 18, 2020
Assignee:
The Regents of the University of California
Inventors:
Jay D. Keasling, Leo D'Espaux, Jeff Wong, Xiaozhou Luo, Michael Reiter, Charles Denby, Anna Lechner
Abstract: Provided is a game information analysis system which is operable to determine whether or not each game played on a gaming machine is a bonus game in order to evaluate a psychological state of a player. An analysis server 2012 of the game information analysis system 2001 receives game information from each slot machine 2014 and previously calculates a normal-time PO from transition of IN/OUT included in the game information in a predetermined period. Thereafter, from the transition of IN/OUT included in game information targeted for an analysis, a game whose PO has a large discrepancy with respect to the normal-time PO is extracted, and it is determined whether or not said game is a bonus game.
Abstract: A wireless local area network (WLAN) communication method and apparatus using multiple transmission speed partitioning and cooperative transmission are disclosed. The WLAN communication method includes transmitting, by access point to the nodes, transmission time slots, partitions and internal transmission priorities using transmission time slot information, partition information and internal transmission priority information, receiving uplink packet from one node, determining whether downlink data to be transmitted to the high speed or the low speed node is present, or not in the download queue, transmitting, if present, the downlink packet to the nodes, removing downlink data from the download queue for ACK, and transmitting, if not present, transmitting ACK to the nodes.
Type:
Grant
Filed:
December 4, 2017
Date of Patent:
February 18, 2020
Assignee:
Research & Business Foundation Sungkyunkwan University
Inventors:
Dong Hyeok An, Yu Sung Kim, Ik Jun Yeom
Abstract: Photoelectrochemical cells including a cathode including alpha-hematite and a metal dichalcogenide, an anode including a conducting polymer, and an electrolyte.
Abstract: An apparatus includes a wireless communication system capable of receiving position information for a plurality of workers in a work zone and a position system capable of providing position information for a piece of movable equipment in the work zone. A processor is capable of receiving the position information for the plurality of workers and the position information for the movable equipment and is capable of determining the position of the workers relative to the position of the movable equipment.
Type:
Grant
Filed:
November 1, 2016
Date of Patent:
February 18, 2020
Assignee:
Regents of the University of Minnesota
Inventors:
M. Imran Hayee, Nazanin Abbaszadeh Banaeiyan, Attiq Uz Zaman