Abstract: Embodiments of the present disclosure provide for nanozymes that can include a therapeutic agent, methods of making nanozymes, methods of using nanozymes, and the like. In some embodiments, the nanozymes can include a shell that can surround a hollow core that can be configured to receive a compound and the shell can include a recognition moiety and an enzyme.

Abstract: The present invention relates to vaccine compositions comprising attenuated strain of Tilapia Lake Virus (TiLV) for protecting tilapia fish against infection by (TiLV). The invention also relates to methods for using the vaccines to protect tilapines from TiLV-induced disease.

Abstract: Nucleic acids encoding mutant elongation factor proteins (EF-Sep), phosphoseryl-tRNA synthetase (SepRS), and phosphoseryl-tRNA (tRNASep) and methods of use in site specific incorporation of phosphoserine into a protein or polypeptide are described. Mutant EF-Sep proteins are disclosed that bind Sep-tRNASep and protect Sep-tRNASep from deacylation. In a preferred embodiment the nucleic acids are on vectors and are expressed in cells such as bacterial cells, archeaebacterial cells, and eukaryotic cells. Proteins or polypeptides containing phosphoserine produced by the methods described herein can be used for a variety of applications such as research, antibody production, protein array manufacture and development of cell-based screens for new drug discovery.

Abstract: A multimodal endoscope apparatus includes optical components (couplers, collimators, mirrors, beam splitters, filters and the like) structured to work together to interact with a multimodal endoscope probe to provide at least two imaging modalities selected from fluorescence imaging, optical coherence tomography, and photoacoustic imaging. The multimodal endoscope probe includes a fiber optic imaging bundle including a multitude of optical fibers. In embodiments employing photoacoustic imaging, the multimodal endoscope probe further includes a polymer-Fabry-Perot interferometer. In some embodiments, a galvo scanner and fiber collimator are included and are together capable of directing light to a single optical fiber of the multitude optical fibers. The system is modular in some embodiments, allowing for switching of some components.

Abstract: Described is a novel method for feature extraction for automatic gait recognition. This method uses Multi-kernel Fuzzy-based Local Gabor Binary Pattern. From a captured gait video sequence, the gait period is determined then a gait energy image is constructed to represent the spatial-temporal variations during one motion cycle of the gait sequence. Then, each gait sequence is represented with a feature vector. The computation of this vector is conducted by first applying the 2D Gabor filter bank then encoding the variations in the Gabor magnitude using a multi-kernel fuzzy local binary pattern operator. Finally, gait classification is performed using a support vector machine.

Abstract: A display method of a transparent display apparatus is provided. The display method includes sensing illumination around the transparent display apparatus; determining threshold lightness using the sensed illumination; correcting image data by changing lightness and chroma of colors which are brighter than the determined threshold lightness by a first method and changing at least one of lightness and chroma of colors which are the determined threshold lightness or less by a second method; and displaying the corrected image data on the transparent display apparatus.

Abstract: According to some aspects, a method is provided of operating a circuit quantum electrodynamics system that includes a physical qubit dispersively coupled to a quantum mechanical oscillator, the method comprising applying a first electromagnetic pulse to the physical qubit based on a number state of the quantum mechanical oscillator, wherein the first electromagnetic pulse causes a change in state of the quantum mechanical oscillator, and applying, subsequent to application of the first electromagnetic pulse, a second electromagnetic pulse to the quantum mechanical oscillator that coherently adds or removes energy from the quantum mechanical oscillator.

Abstract: A method of generating an image of a scanned subject includes: emitting, by multiple ultrasonic elements of an array, multiple respective ultrasonic signals into a subject, the multiple respective ultrasonic signals defining at least two beam portions traveling in different directions; receiving, by the multiple ultrasonic elements, multiple respective ultrasonic echo signals; and generating at least one image of a portion of the subject from the received multiple ultrasonic echo signals. A negatively focused wavefront including the at least two beam portions traveling in the different directions may be emitted. Multiple negatively focused wavefronts may be generated and emitted.

Abstract: Processing an image includes acquiring, by the image processing apparatus, a target image, extracting a shape of a target object included in the target image, determining a category including the target object based on the extracted shape, and storing the target image by mapping the target image with additional information including at least one keyword related to the category.

Abstract: The present invention provides an antibody to a fibrosis-related molecule and medical application thereof. The antibody of the present invention is an antibody that binds to CHL1 protein and an antibody that neutralizes the binding of the CHL1 protein to a fibroblast.

Abstract: Embodiments for systems and methods of sequential event prediction with noise-contrastive estimation for marked temporal point process are disclosed.

Abstract: The disclosed embodiments relate to a system that uses a video game to improve spatial and/or temporal information-processing capabilities of a user. During operation, the system enables the user to play the video game. During execution of the video game, the system first measures spatial and/or temporal information-processing capabilities of the user during the course of playing the video game. Next, the system uses the measured spatial and/or temporal information-processing capabilities to control a spatial placement and/or a temporal presentation rate of target items that the user is required to respond to during subsequent game play to stimulate enhancement of the user's spatial and/or temporal information-processing capabilities.

Abstract: A nanoporous metal can be formed by projecting laser patterns using a spatial light modulator (SLM) onto a gold/silver alloy film immersed in diluted nitric acid solutions. Heat accumulation induced by the photothermal effect enables localized dealloying in dilute nitric acid. NPG micropatterns can be formed at the irradiated spots while the surrounding alloy remains intact.

Abstract: Provided herein are methods and compositions for enhancing an immune response and/or for the treatment of an immune-related condition in an individual, e.g., cancer, comprising killing, disabling, or depleting non-stimulatory myeloid cells using an antigen binding protein such as an antibody or antigen binding fragment thereof.

Abstract: A chlorine neutralizer which can be used and manufactured in a simplified manner, a throw-in type chlorine neutralizer containing the same, a chlorine neutralizing apparatus, and a chlorine neutralizing method are provided. A chlorine neutralizer which neutralizes a chlorine-based component contains at least one selected from a vinyl alcohol based polymer and a polyamide resin, and the vinyl alcohol based polymer contains at least vinyl alcohol in a repeating structural unit.

Abstract: Provided are a method for promoting the proliferation of pluripotent stem cells and a proliferation promoting composition used in the method. In one aspect, a composition for promoting the proliferation of pluripotent stem cells includes hemagglutinin or modified hemagglutinin. In another aspect, a method for promoting the proliferation of pluripotent stem cells includes culturing pluripotent stem cells in a culture medium to which the proliferation promoting composition of the present disclosure has been added.

Abstract: A building quality inspection system includes a controller, a drone, and a robot that are communicably connected to one another. The controller includes circuitry configured to, when exterior of a building is inspected, sends an inspection objective to the drone to instruct the drone to carry out a visual inspection of the exterior of the building, receives inspection data collected by the drone during the visual inspection of the exterior of the building, extracts a location where damage is suspected from the inspection data collected by the drone, sends the location where damage is suspected to the robot to carry out an exterior inspection at the location where damage is suspected, receives inspection data collected by the robot during the exterior inspection, and determines current quality of the exterior of the building based on the inspection data collected by the drone and the robot.

Abstract: The present invention discloses a device and methods for the analysis of secreted molecules from a single cell. As described herein, the invention incorporates individual microwells with a bottom surface capable of capturing a cell and allows the release of secreted molecules to be printed onto a capture surface. The device provides accurate identification of the cell source of the printed molecules by mapping the printed molecules to the cell source. The invention further employs spectrometry, immunoassay or label free Surface Plasmon Resonance imaging for detection of the secreted molecules in combination with a microwell array, where single cells are seeded in individual microwells and the secreted molecules are captured by the capture surface in an array print while the cell remains in the microwell for additional interrogation. The present invention has applications in medical research and diagnosis where individual target cells in a fluid sample are interrogated for the secreted products.

Abstract: The present invention includes compositions and methods for identifying cancer driver mutations through use of an AAV-CRISPR library and molecular inversion sequencing probes (MIPs).

Abstract: A driving assistance system includes a driving readiness degree estimation unit configured to estimate a driving readiness degree relating to a driving consciousness of the driver based on the travel state of the vehicle or the driving operation of the vehicle by the driver and the traveling environment of the vehicle, a proportional gain calculation unit configured to calculate a proportional gain based on the driving readiness degree and the speed of the vehicle, and an assistance torque calculation unit configured to calculate the assistance torque according to a value obtained by multiplying a difference between the target steering angle and the actual steering angle by the proportional gain. If the speed is constant, the proportional gain calculation unit is configured to calculate the proportional gain as a smaller value as the driving readiness degree becomes lower.