Abstract: The present invention provides a compound having the structure: wherein R1, R2, R3, R4, and R5 are each independently H, halogen, CF3 or C1-C4 alkyl, wherein two or more of R1, R2, R3, R4, or R5 are other than H; R6 is H, OH, or halogen; and B is a substituted or unsubstituted heterobicycle, wherein when R1 is CF3, R2 is H, R3 is F, R4 is H, and R5 is H, or R1 is H, R2 is CF3, R3 is H, R4 is CF3, and R5 is H, or R1 is Cl, R2 is H, R3 is H, R4 is F, and R5 is H, or R1 is CF3, R2 is H, R3 is F, R4 is H, and R5 is H, or R1 is CF3, R2 is F, R3 is H, R4 is H, and R5 is H, or R1 is Cl, R2 is F, R3 is H, R4 is H, and R5 is H, then B is other than or a pharmaceutically acceptable salt thereof.

Abstract: The present disclosure relates to compositions and methods for modulating T-cell mediated immune response in a subject in need thereof. The method includes administering to the subject an effective amount of a CD112R protein, a fusion polypeptide, a complex including CD112R and a second protein, or an anti-CD112R antibody of the present disclosure.

Abstract: A sensor comprising a semiconductor layer having a two dimensional electron gas (2DEG) and an oxide layer in electronic contact with the semiconductor layer is provided. A method of detecting an analyte molecule using such sensor is also provided.

Abstract: A method and system for die compensation and restoration uses high-velocity oxy-fuel (HVOF) thermal spray coating and plasma ion nitriding to compensate for a particular part (damaged part) of a press die that causes formation of fine curves at a door of a vehicle to restore it to its original state. A coating thickness quantification technique may precisely compensate for the damaged part of the die that causes formation of the fine curves at the door of the vehicle in a circular form using HVOF thermal spray coating. A surface of the die may be nitrided using plasma ion nitriding after HVOF thermal spray coating is performed, so as to harden the surface of the die so that wear resistance and fatigue resistance of the die can be greatly improved and the hardfacing or overlay welding efficiency of the die can be increased.

Abstract: Provided are processes for isolating hemicellulose-based sugar from a biomass. The process includes providing a biomass hydrolyzate including a C5 sugar, forming a boronic ester or diester of the C5 sugar, extracting the boronic ester of diester of the C5 sugar, precipitating the C5 sugar using a boron capture agent, and isolating the C5 sugar from the precipitate. The isolated C5 sugar is provided in dry form.

Abstract: Red mud-based geopolymer compositions and methods of their preparation are described. The red mud-based geopolymer compositions can be cured at ambient temperatures using alkaline solutions of relatively low alkaline compound concentration compared to other geopolymer compositions. In particular, the use of a red mud previously utilized in a flue gas desulfurization process can provide high strength geopolymer compositions.

Abstract: An amusement park attraction includes an attraction feature. The attraction feature includes a fluid actuator having an inflatable mass, the inflatable mass being fluidly connected to a source of pressurized fluid to enable inflation of the inflatable mass. Fluid control devices are configured to adjust inflation of the inflatable mass, and sensors are configured to monitor state properties of the fluid actuator. A controller is communicatively coupled to the fluid control devices and the sensors. The controller is configured to controllably inflate the inflatable mass based at least on feedback from the sensors to cause the fluid actuator to impact an object. The controller is configured to control the inflation of the inflatable mass to adjust parameters of the fluid actuator to maintain a force exerted by the fluid actuator on the object to within a predetermined range.

Abstract: A method of forming a chalcogenophene compound of formula (I) includes reacting a compound of formula (II) with a chalcogenide salt in presence of a proton source. Y is O, S, Se, Te or Po. R1 is hydrogen, deuterium, an aliphatic, heteroaromatic, or aromatic group, or a precursor of a leaving group Z whose conjugate acid (HZ) has pKa less than 30. R2 is hydrogen, deuterium, or an aliphatic, heteroaromatic, or aromatic group. R1 and R2 may be the same or different, and may joint together to form a saturated or unsaturated, heteroalicyclic or alicyclic ring. R3 is, for example, alkyl, aryl, heteroaryl, organosilyl, organotin, or organogermyl. R3? is the same as R3 or is hydrogen. X is a precursor of a leaving group X whose conjugate acid (HX) has a pKa of less than 30.

Abstract: A static memory cell capable of balancing bit line leakage currents is characterized by including a 1st PMOS transistor, a 2nd PMOS transistor, a 1st NMOS transistor, a 2nd NMOS transistor, a 3rd NMOS transistor, a 4th NMOS transistor, a 5th NMOS transistor, a 6th NMOS transistor, a 7th NMOS transistor, an 8th NMOS transistor, a write word line, a read word line, a read bit line, an inverted read bit line, a write bit line and an inverted write bit line. The 1st NMOS transistor, the 2nd NMOS transistor, the 3rd NMOS transistor and the 4th NMOS transistor are all normal threshold NMOS transistors. The 1st PMOS transistor and the 2nd PMOS transistor are both low threshold PMOS transistors. The 5th NMOS transistor, the 6th NMOS transistor, the 7th NMOS transistor and the 8th NMOS transistor are all low threshold NMOS transistors. The static memory cell has the advantages of high read operation speed, low power consumption and high stability under low operating voltage conditions.

Abstract: A plasmonic sensor includes at least a substrate and a thin film metallic glass formed on the substrate. The dielectric constant (?r) of the thin film metallic glass is negative. Since the thin film metallic glass with negative ?r is used in the plasmonic sensor, the material cost can be significantly reduced, the mechanical property can be improved, and the optoelectronic property can be increased. Since the thin film metallic glass is a kind of supercooled alloy with amorphous structure, it can be applied for imprinting deformation and amorphous without grain boundary scattering.

Abstract: The present invention relates to an apparatus for tracking a device comprising a magnet as the device is inserted through a subject. The apparatus is wearable by the subject and comprises a unit configured to conform to the subject. The apparatus further comprises magnetic sensors arranged with the unit. In use, the magnetic sensors detect magnetic fields of the magnet and the detected magnetic fields are processed to determine a position of the magnet. This allows tracking of the device as the device is inserted through the subject.

Abstract: In some aspects, the invention relates to compositions comprising marrow infiltrating lymphocytes (“MILs”). The MILs may be activated MILs. In some aspects, the invention relates to methods for activating MILs, comprising incubating MILs in an environment comprising less than 21% oxygen. In some aspects, the invention relates to methods for treating cancer in a subject, comprising administering to the subject a composition comprising activated MILs.

Abstract: A diffuse reflectance spectroscopy system for determining an optical property of a specimen and a method for operating the same are provided. The system includes: a light emitting unit comprising a light emitting terminal, the light emitting unit configured to emit steady light; an optical medium arranged at one end of the device, the optical medium being controllable to switch between multiple optical states and configured to deliver the steady light to the specimen through the optical medium in different optical states, wherein the optical medium comprises a first surface in contact with the light emitting terminal of the light emitting unit and a second surface for contact with the specimen; and a detecting module comprising one or more receiving terminals for receiving light scattered from the specimen for determining the optical property of the specimen.

Abstract: Disclosed are a video encoding/decoding method and apparatus including a plurality of views. The video decoding method including the plurality of views comprises the steps of: inducing basic combination motion candidates for a current Prediction Unit (PU) to configure a combination motion candidate list; inducing expanded combination motion candidates for the current PU when the current PU corresponds to a depth information map or a dependent view; and adding the expanded combination motion candidates to the combination motion candidate list.

Abstract: A monolithic reusable microwire assembly can include a substrate and an electrically conductive thin-film wire formed on the substrate. The conductive thin-film wire can include a narrow segment forming an active area. A thermally and electrically insulating barrier can be formed on the electrically conductive thin-film wire. A roughness-reducing layer can be formed on the thermally and electrically insulating barrier and can have minimal surface roughness.

Abstract: The invention generally relates in part to methods of effecting weight loss and/or improving glucose tolerance in a patient in need thereof, comprising administering a MetAP2 inhibitor.

Abstract: Provided are methods for treating a neurodegenerative disease, such as multiple sclerosis, in a subject receiving a first estriol treatment regimen, comprising obtaining a measurement of the serum estriol concentration in the blood of the subject, and administering a second estriol treatment regimen to the subject if the serum estriol concentration is less than 6 ng/mL. The daily amount of estriol administered during the second estriol treatment regimen is preferably greater than the daily amount of estriol administered during the first estriol treatment regimen.

Abstract: A communication system that minimizes the transmission of pilot symbols while ensuring real-time channel tracking and symbol detection. The system employs a multiple-input multiple-output (MTMO) transmitter-receiver pair where there are many more receive antennas than transmit antennas. Communication occurs over a wide band RF channel via orthogonal frequency division multiplexing (OFDM) that employs a large number of sub-carriers.

Abstract: First, second, and third integrated devices each include one or more interconnecting structure. Each interconnecting structure includes (i) one or more interconnecting nodules extending from an edge surface of the device, (ii) one or more interconnect voids formed in an edge surface of the device, or (iii) both (i) and (ii). The one or more interconnecting structures on each of the first and second device is mated with the one or more interconnecting structures on the second device. The first integrated device includes a signal output, the third integrated device includes a signal input; and the second integrated device includes a conductor for conducting a signal from the signal output to the signal input.

Abstract: A method for fast high-resolution deep photoacoustic tomography of action potentials in brains is provided herein. The method may utilize a high-speed, high-spatial-resolution, deep-penetration photoacoustic computed tomography (PACT) system for real-time imaging of action potentials.