Patents Assigned to University
  • Methods and apparatus for image construction
    Patent number: 10332279
    Abstract: A method constructs an image with improved peak signal-to-noise ratio (PSNR) from a scattered pixel set. The method generates an approximation function that is a linear combination of a plurality of Many-Knot (MK) spline basis functions, and constructs the image with improved PSNR by conducting a least squares treatment on the approximation function to minimize a residual of each pixel value in the scattered pixel set from the approximation function.
    Type: Grant
    Filed: March 3, 2017
    Date of Patent: June 25, 2019
    Assignee: Macau University of Science and Technology
    Inventors: Zhanchuan Cai, Ting Lan
  • Antagonistic PD-1 aptamer and its applications in cancer therapy related applications
    Patent number: 10329570
    Abstract: Aptamers that bind to and antagonize programmed cell death protein 1 (PD-1). Also provided herein are pharmaceutical compositions comprising such anti-PD-1 aptamers and methods for using the same for promoting T cell proliferation, treating cancer or infectious diseases, such as human immunodeficiency virus (HIV) infection.
    Type: Grant
    Filed: July 31, 2015
    Date of Patent: June 25, 2019
    Assignees: Academia Sinica, National Taiwan University
    Inventors: Pan-Chyr Yang, Yi-Chung Chang, Wei-Yun Lai
  • Switched capacitor house of cards power amplifier
    Patent number: 10333477
    Abstract: A circuit topology including stacked power amplifiers (e.g., class D PA cells) in a ladder arranged in a house-of-cards topology such that the number of stacked-domains follows a decaying triangular series N, N?1, N?2, . . . , N?i from a fixed ladder to an ith ladder to provide a 1:(i+1) voltage conversion ratio, each stacked domain outputs its power via a flying domain power amplifier cell, and each ladder balances stacked domains of a prior ladder and combines power from all prior ladders.
    Type: Grant
    Filed: September 7, 2017
    Date of Patent: June 25, 2019
    Assignee: The Regents of the University of California
    Inventors: Loai Galal Bahgat Salem, James F. Buckwalter, Patrick P. Mercier
  • System, method, and apparatus for dynamically replicating data for heterogeneous Hadoop
    Patent number: 10331700
    Abstract: A system for dynamically replicating data for a heterogeneous Hadoop is provided. The system includes a name node having a replication manager. The replication manager calculates a probability that a map task is allocated to a map task slot of a data node that stores an input data block of the map task out of a plurality of map task slots of data nodes by using a number of the map task slots in the Hadoop clusters comprised of heterogeneous clusters, and dynamically replicates data based on the probability.
    Type: Grant
    Filed: November 22, 2016
    Date of Patent: June 25, 2019
    Assignee: Foundation of Soongsil University-Industry Cooperation
    Inventors: Jiman Hong, Daeshin Park, Kisu Kim
  • Method of forming microparticles for use in cell seeding
    Patent number: 10329528
    Abstract: The present invention is directed to methods for forming microparticles useful for cell seeding and for conjugating protein to the surface of the microparticles. The method comprises co-injecting an organic solution of PLGA or other polymer with an aqueous solution into a flow focusing tube.
    Type: Grant
    Filed: April 6, 2017
    Date of Patent: June 25, 2019
    Assignee: The Curators of the University of Missouri
    Inventors: Sutapa Barua, Chase Herman
  • Self-restoring macromolecular material and production method for same
    Patent number: 10329386
    Abstract: Provided is a self-restoring macromolecular material that not only has excellent stress relaxation but that can also be easily restored to its original state, even when damaged or severed. Also provided is a method for producing the self-restoring macromolecular material. The self-restoring macromolecular material contains a crosslinked structure that is formed by crosslinking a polymer containing at least a polyrotaxane molecule. The polyrotaxane molecule is formed so as to include a cyclic molecule 21 and a linear molecule that passes through an opening 21a of the cyclic molecule. The crosslinked structure 1 is crosslinked via a reversible bond between the cyclic molecule of the polyrotaxane molecule and a polymer molecule other than the polyrotaxane molecule.
    Type: Grant
    Filed: June 19, 2015
    Date of Patent: June 25, 2019
    Assignee: Osaka University
    Inventors: Akira Harada, Yoshinori Takashima, Yuichiro Kobayashi, Masaki Nakahata, Shoko Mori
  • Process mapping of average temperatures and process sensitivity
    Patent number: 10328532
    Abstract: In one aspect, a method includes conducting a plurality of tests on process variables of a thermal process, with a test of the plurality of tests being conducted on two or more process variables, the test comprising: locally heating a region of a structure, wherein the local heating results in formation of a thermal field in the structure; assessing one or more temperature integrals of the thermal field; and based on results of the plurality of tests, generating a process map of the one or more temperature integrals of the thermal field, with the one or more temperature integrals based on a function of the two or more process variables.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: June 25, 2019
    Assignee: Carnegie Mellon University
    Inventor: Jack Lee Beuth, Jr.
  • System and method for stability control in adjustable speed drive with DC link thin film capacitor
    Patent number: 10333444
    Abstract: A control system for actively damping an output of an adjustable speed drive (ASD) having a DC link thin film capacitor is programmed to calculate a d-axis damping coefficient and a q-axis damping coefficient for stabilizing an output of the ASD based at least on a voltage across the DC link thin film capacitor at a steady operating point. The control system is further programmed to extract d-axis and q-axis perturbations in d-axis and q-axis output currents of the ASD using a high pass filter, damp the d-axis perturbation and the q-axis perturbation with the d-axis damping coefficient and the q-axis damping coefficient, respectively, and calculate a damping frequency based on the damped d-axis perturbation and the damped q-axis perturbation. The control system is also programmed to damp an angle of rotation of a reference motor speed command for controlling the ASD using the damping frequency.
    Type: Grant
    Filed: August 31, 2017
    Date of Patent: June 25, 2019
    Assignees: Eaton Intelligent Power Limited, Zhejiang University
    Inventors: Huaqiang Li, Wenxi Yao, Zhentian Qian
  • Optical phase modulation systems and methods
    Patent number: 10330595
    Abstract: Methods, systems, and devices for particle characterization by optical phase modulation and detection of aerosol backscattering. In some aspects, a compact and cost effective particle detector device to measure the aerosol density and its size distribution by backscattered focusing using projected optical modified field distribution imaging into the aerosol medium (air). The disclosed device can be used in a variety of scientific and industrial applications, e.g., such as a particle sensor for automobiles able to detect harmful pollution which may then be filtered from the car cabin, or warnings provided to the driver. The device can also capture and store data, enabling detailed pollution maps of various roadways in real-time.
    Type: Grant
    Filed: October 19, 2016
    Date of Patent: June 25, 2019
    Assignee: The Regents of the University of California
    Inventors: Lin Pang, Yeshaiahu Fainman, Andrew C. Kummel, Brandon Hong
  • Purification of carbon nanotubes via selective heating
    Patent number: 10333069
    Abstract: The present invention provides methods for purifying a layer of carbon nanotubes comprising providing a precursor layer of substantially aligned carbon nanotubes supported by a substrate, wherein the precursor layer comprises a mixture of first carbon nanotubes and second carbon nanotubes; selectively heating the first carbon nanotubes; and separating the first carbon nanotubes from the second carbon nanotubes, thereby generating a purified layer of carbon nanotubes. Devices benefiting from enhanced electrical properties enabled by the purified layer of carbon nanotubes are also described.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: June 25, 2019
    Assignees: The Board of Trustees of The University of Illinois, Northwestern University, University of Miami
    Inventors: John A. Rogers, William L. Wilson, Sung Hun Jin, Simon N. Dunham, Xu Xie, Ahmad Islam, Frank Du, Yonggang Huang, Jizhou Song
  • Composition for inducing proliferation or accumulation of regulatory T cells
    Patent number: 10328108
    Abstract: It was found that bacteria belonging to the genus Clostridium induce accumulation of regulatory T cells (Treg cells) in the colon. Moreover, the present inventors found that regulatory T cells (Treg cells) induced by from these bacteria suppressed proliferation of effector T-cells. From these findings, the present inventors found that the use of bacteria belonging to the genus Clostridium or a physiologically active substance derived therefrom made it possible to induce proliferation or accumulation of regulatory T cells (Treg cells), and further to suppress immune functions.
    Type: Grant
    Filed: October 26, 2018
    Date of Patent: June 25, 2019
    Assignee: The University of Tokyo
    Inventors: Kenya Honda, Koji Atarashi, Kikuji Itoh, Takeshi Tanoue
  • Live-attenuated vaccine against plague
    Patent number: 10328139
    Abstract: Provided herein is a genetically modified Y. pestis that includes three alterations compared to a control Y. pestis. Two alterations include decreased mRNA, decreased protein, or a combination thereof, encoded by a lpp coding region and encoded by a msbB coding region. The third alteration is selected from an alteration of an intergenic region between the coding regions ypo1119 and ypo1120, and decreased mRNA, decreased protein, or a combination thereof, encoded by a coding region selected from pla, ypol717, ypmt1.80c, rbsA (ypo2500), ypo0498, vasK (ypo3603), ypo3164, hxuB (ypo3248), ypo1616, ypo1119, ypo1120, and ail. Also provided are compositions that include the genetically modified Y. pestis, and methods of using the genetically modified Y. pestis.
    Type: Grant
    Filed: January 14, 2016
    Date of Patent: June 25, 2019
    Assignee: The Board of Regents of the University of Texas System
    Inventors: Ashok K. Chopra, Jian Sha
  • Method of refining metal alloys
    Patent number: 10329651
    Abstract: Method of refining metal alloys A method of refining the grain size of (i) an alloy comprising aluminum and at least 3% w/w silicon or (ii) an alloy comprising magnesium, comprises the steps of (a) adding sufficient niobium and boron to the alloy in order to form niobium diboride or Al3Nb or both, or (b) adding niobium diboride to the alloy, or (c) adding Al3Nb to the alloy, or (d) any combination thereof.
    Type: Grant
    Filed: February 10, 2012
    Date of Patent: June 25, 2019
    Assignee: Brunel University London
    Inventors: Hari Babu Nadendla, Magdalena Nowak
  • Alginate biomaterials for the treatment of hepatic disorders
    Patent number: 10328098
    Abstract: The present invention relates to methods for the treatment of hepatic disorders in a subject in need thereof. More specifically, the methods of the invention are based on the administration, preferably, systemic administration, of a therapeutically effective amount of at least one biocompatible alginate biomaterial, any modification thereof and any combination thereof. The invention further provides methods for sustaining serum albumin levels, and/or reducing serum AST and ALT, in subjects suffering from hepatic disorder. Still further, the invention provides methods for reducing apoptosis and inducing cell proliferation in a damaged liver tissue of a subject suffering of hepatic disorder, using the alginate biomaterial described by the invention.
    Type: Grant
    Filed: July 10, 2016
    Date of Patent: June 25, 2019
    Assignees: Hadasit Medical Research Services and Development Ltd., Ben-Gurion University of the Negev Research and Development Authority
    Inventors: Yaron Ilan, Gadi Lalazar, Eyal Shteyer, Ami Ben-Ya'acov, Smadar Cohen, Tsiona Elkayam
  • Stimulation devices and methods
    Patent number: 10328262
    Abstract: Described here are stimulation systems and methods for stimulating one or more anatomical targets in a patient for treatment conditions such as dry eye. The stimulation system may include a controller and a microstimulator. The components of the controller and microstimulator may be implemented in a single unit or in separate devices. When implemented separately, the controller and microstimulator may communicate wirelessly or via a wired connection. The microstimulator may generate pulses from a signal received from the controller and apply the signal via one or more electrodes to an anatomical target. In some variations, the microstimulator may include a passive generation circuit configured to generate a pulse based on a signal received from the controller.
    Type: Grant
    Filed: November 2, 2017
    Date of Patent: June 25, 2019
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Oculeve, Inc.
    Inventors: Douglas Michael Ackermann, James Donald Loudin, Janusz Kuzma, Daniel Palanker, Scott Franklin Wetenkamp
  • Measurement of blood volume using velocity-selective pulse trains on MRI
    Patent number: 10330762
    Abstract: The present invention is directed to a system and method for measuring blood volume using non-contrast-enhanced magnetic resonance imaging. The method of the present invention includes a subtraction-based method using a pair of acquisitions immediately following velocity-sensitized pulse trains for the label module and its corresponding control module, respectively. The signal of static tissue is canceled out and the difference signal comes from the flowing blood compartment above a cutoff velocity. After normalizing to a proton density-weighted image acquired separately and scaled with the blood T1 and T2 relaxation factors, quantitative measurement of blood volume is then obtained.
    Type: Grant
    Filed: April 12, 2017
    Date of Patent: June 25, 2019
    Assignee: The Johns Hopkins University
    Inventor: Qin Qin
  • Method of converting red phosphorous to soluble polyphosphides using alkali metal compounds in a combination of tetrahydrofuran and dimethoxyethane
    Patent number: 10329151
    Abstract: A method of generating soluble polyphosphides using solution chemistry is presented. A reaction between potassium ethoxide in THF/DME and shelf stable red phosphorus generated soluble polyphosphides in a variety of organic solvents with the 31P NMR spectrum being used to detect the species of polyphosphides produced.
    Type: Grant
    Filed: October 10, 2018
    Date of Patent: June 25, 2019
    Assignee: The Flrida State University Research Foundation, Inc.
    Inventors: Michael Shatruk, David Tyler McQuade, Alina Dragulescu-Andrasi, Levi Zane Miller, Chongin Pak
  • Nonlinear noise cancellation in wavelength division multiplexing (WDM) systems
    Patent number: 10333645
    Abstract: A method that may include receiving a block of signals from a certain wavelength division multiplex (WDM) channel out of a set of WDM channels; analyzing at least a first sub-block of signals of the block of signals to provide analysis results indicative of interferences that affect the first sub-block of signals and result from transmissions over other WDM channels of the set of WDM channels; and mitigating interferences that affect the block of signals in response to the analysis results.
    Type: Grant
    Filed: November 13, 2014
    Date of Patent: June 25, 2019
    Assignee: RAMOT at Tel Aviv University Ltd
    Inventors: Meir Feder, Ronen Dar, Mark Shtaif, Antonio Mecozzi
  • Methods for forming gold nanowires on a substrate and gold nanowires formed thereof
    Patent number: 10332657
    Abstract: A method for forming gold nanowires on a substrate is provided. The method includes a) attaching noble metal nanoparticles onto the substrate; and b) contacting the noble metal nanoparticles with an aqueous solution comprising a ligand, gold ions and a reducing agent, wherein the ligand is an organic compound having a thiol group. Gold nanowires formed by a method according to the method, and an electronic device comprising the gold nanowires are also provided.
    Type: Grant
    Filed: September 24, 2012
    Date of Patent: June 25, 2019
    Assignee: Nanyang Technological University
    Inventors: Hongyu Chen, Jiating He, Yawen Wang
  • Cell collection and centrifuge tube assembly
    Patent number: D852375
    Type: Grant
    Filed: October 25, 2017
    Date of Patent: June 25, 2019
    Assignee: Wake Forest University Health Sciences
    Inventors: John David Druga, Sr., Philip Jayson Brown, Aaron Van Gorkom