Abstract: A method of assembling an opto-physiological (OP) sensor comprises: (i) modelling the opto-physiological properties of at least one body tissue type to be monitored; (ii) determining, through application of the model, an optimal optical design for an opto-physiological (OP) sensor operable to monitor the opto-physiological properties of the at least one body tissue type; and (iii) making the OP sensor to the determined optical design. The optimal optical design for the OP sensor comprises: (i) determining the optimum separation of each of a plurality of light sources from a photodetector, based on modelled optical path lengths for light travelling from each light source, through the body tissue type to be monitored, to the photodetector; and (ii) locating light sources of different wavelengths at different distances from the photodetector.

Abstract: An system for recognition of a translocating polymeric target molecule includes a device having at least one constriction that is sized to permit translocation of only a single copy of the molecule. A pair of spaced apart sensing electrodes border the constriction, which may be a nanopore. The first electrode is connected to a first affinity element and the second electrode is connected to a second affinity element. Each affinity element may connected to its corresponding electrode via one or more intermediary compounds, such as a linker molecule and/or an electrode attachment molecule. The first and second affinity elements are configured to temporarily form hydrogen bonds with first and second portions of the target molecule as the latter passes through the constriction. During translocation, the electrodes affinity elements and first and second portions of the target molecule complete an electrical circuit and allow a measurable electrical current to pass between the first and second electrodes.

Abstract: A magnet assembly for use in high power pulsed magnetron sputtering comprises a configuration of magnets having a magnetic field topology comprising magnetic field components Bx, By and Bz. A tangential magnetic field B// distribution on an x-y plane above the configuration of magnets comprising an outer continuous ring and one or more inner continuous rings contained in the outer continuous ring. A total magnetic field Btot distribution on an x-z plane intersecting the configuration of magnets comprises an outer closed loop and one or more inner closed loops contained in the outer closed loop, where, as a function of x, a tangential magnetic field B// alternates between (a) high field values greater than 200 G and high gradients in the z-direction of at least 1000 G/in, and (b) low field values of less than 50 G and low gradients in the z-direction of at most 250 G/in.

Abstract: A photoelectric semiconductor nanowire device and a method for manufacturing the same. The photoelectric semiconductor nanowire device includes a semiconductor nanowire doped with a dopant of a first conductivity type and including crystal semiconductor segments which include at least one porous semiconductor segment and are connected to opposite ends of the porous semiconductor segment. A first electrode and a second electrode respectively are disposed in the crystal semiconductor segments around the porous semiconductor segment to provide an electrical connection. The crystal semiconductor segment includes a crystal semiconductor, and the porous semiconductor segment includes a porous semiconductor. The semiconductor nanowire provides a current according to the intensity of an external light when the external light is irradiated to the porous semiconductor segment.

Abstract: A method of synthesizing soluble polyphosphides using shelf-stable reagents and common organic solvents is presented. A reaction between an alkali metal alkoxy compound or alkali metal alkyl thiolate compound and shelf stable red phosphorus generated soluble polyphosphides in a variety of organic solvents with the 31P NMR spectrum being used to detect the species of polyphosphides produced.

Abstract: The apparatus and method for testing the ability of materials to protect photolabile materials provides an accurate measurement by directly observing the degradation level in a photolabile material. The apparatus is an assembly having primary and secondary cells and a light source. The primary and secondary cells are arranged in different configurations with respect to one another such that any light that reaches the photolabile materials must first go through the protective material under test. The method includes placing a protective material under test in the primary cell; placing a photolabile material in the secondary cell; subjecting the assembly to a light source for a predetermined amount of time; and removing and testing the photolabile material for degradation.

Abstract: An imaging system images near-field objects with focused microwave or terahertz radiation. Multiple antennas emit microwave or terahertz radiation, such that the radiation varies in frequency over time, illuminates a near-field object, reflects from the near-field object, and travels to a passive aperture. For example, the passive aperture may comprise a dielectric lens or a parabolic reflector. The passive aperture focuses, onto a spatial region, the microwave or terahertz radiation that reflected from the near-field object. One or more antennas take measurements, in the spatial region, of the microwave or terahertz radiation that reflected from the near-field object. A computer calculates, based on the measurements, an image of the near-field object and depth information regarding the near-field object.

Abstract: A method and apparatus for polarizing nuclear or electronic spins is disclosed. An analyte is passed near a surface that has a plurality of spin defect centers implanted within 10 nm of the surface. The spin defect centers are exposed to a magnetic field and illumination to produce polarized spins. The polarized spins then induce spin polarization in the analyte.

Abstract: There is disclosed squaraine compounds of formula I: wherein each of Y1 and Y2 is independently chosen from an optionally substituted amino group and an optionally substituted aryl group. Also described are organic optoelectronic devices comprising a Donor-Acceptor heterojunction that is formed from one or more of the squaraine compounds. A method of making the disclosed device, which may include one or more sublimation step for depositing said squaraine compound, is also disclosed.

Abstract: The sulindac derivatives are compounds of the formula: wherein R is one of twenty-five substituted or unsubstituted phenyl substituents; and pharmaceutically acceptable salts thereof. The sulindac derivatives are synthesized by refluxing sulindac hydrazide with appropriately substituted benzaldehydes in the presence of ethanol and catalytic amounts of glacial acetic acid. The sulindac derivatives may be used as active ingredients in pharmaceutical compositions for the treatment of inflammation or inflammatory diseases. The sulindac derivatives may also be used as analgesic and/or gastric sparing agents.

Abstract: An apparatus includes: a first inductor coupled to a first node and a second node; a second inductor coupled to a third node and a fourth node; a third inductor coupled to the fourth node and a fifth node, wherein the first inductor, the second inductor, and the third inductor form a transformer; and a compensation capacitor coupled to the fourth node and one of the first node and the second node and including, a compensation capacitance. A method of manufacturing a resonant converter, the method includes: obtaining the resonant converter, wherein the resonant converter includes a transformer; determining a parasitic capacitance of the transformer; calculating a compensation capacitance based on the parasitic capacitance; and adding a compensation capacitor across the transformer, wherein the compensation capacitor includes the compensation capacitance.

Abstract: Systems and methods for inhibiting atherosclerosis using FoxP3+ CD8 T-cells (TcREG). Osteoclasts are induced to produce FoxP3+ CD8 T-cells (TcREG) through introduction of a low-dose of a RANK agonist suck as RANKL. The RANKL was found to best work when provided in accordance with a schedule resulting in a pulsed administration.

Abstract: A linear element with two stable points, it can be used as trust element allows for change in length. It can transform structure from one shape to another thus allowing for morphable configuration. A new model is presented herein for a linear bi-stable compliant mechanism and design guidelines for its use. The mechanism is based on the crank-slider mechanism. This model takes into account the first mode of buckling and post-buckling behavior of a compliant segment to describe the mechanism's bi-stable behavior. The kinetic and kinematic equations, derived from the Pseudo-Rigid-Body Model, were solved numerically and are represented in plots. This representation allows the generation of step-by-step design guidelines. Because different applications may have different input requirements, two different design approaches are described herein with different parameters subsets as inputs.

Abstract: The present disclosure features a condensation reaction and a luciferin-unmasking reaction that can be carried out under physiological conditions. In general, the condensation reaction involves reacting a bicyclic reactant with an aminothiol derivative, generating a luciferin or luciferin derivative. A luciferin can provide detectable luminescence. A luciferin derivative can be unmasked to provide detectable luminescence in a luciferin-unmasking reaction. The present disclosure provides bicyclic reactants and aminothiol derivatives suitable for use in the condensation reaction. The condensation and luciferin-unmasking reactions find use in a variety of applications, which are also provided.

Abstract: Disclosed is a system and method for using visible light communication (“VLC”) to perform indoor position location. Through use of a system and method configured as set forth herein, the position of any appropriately marked person or item may be found indoors using data interconnected modules that communicate with one another via RF and visible light. A mobile receiver in the form of a tag or badge attached to the person or item to be tracked receives a VLC signal from a plurality of lighting modules, and transmits back to a mesh network formed by the modules the data it received to determine the tag's or badge's physical position with respect to the individual network modules.

Abstract: Embodiments of a shearography system may include light sources configured to produce beams of light to illuminate a test area. Each of the beams of light may include a different wavelength. A camera may be configured to obtain intensity information corresponding to reflections of the lights off of the test area. An optical shearing device may be disposed in an optical path between the light sources and the camera and the optical shearing device may be configured to provide a shearing angle.

Abstract: A glucose rate increase detector (GRID) for use in an artificial pancreas (AP), wherein the GRID detects in a person persistent increases in glucose associated with a meal, and either triggers a meal bolus to blunt meal peak safely, during closed-loop control, or alerts the person to bolus for a meal, during open-loop control.

Abstract: Disclosed herein are biomarkers of platelet function and methods for assessing platelet function in response to anti-platelet therapy and for determining a prognosis, diagnosis, or risk identification in a patient by detecting at least one biomarker of platelet function in the patient as well as determining amounts thereof. The biomarkers may be used to identify a patient as a candidate for treatment with an antiplatelet agent and to monitor and adjust antiplatelet therapy in a patient.

Abstract: A configuration of a DFB laser-based wavelength tunable laser is well known, but long resonators have difficulty in forming uniform resonators due to production variations, thereby inducing limitation in narrowing the spectral linewidth in the DFB laser-based wavelength tunable laser as well. In the semiconductor laser device of the present invention, a semiconductor laser that oscillates in a single mode and a low-loss lightwave circuit using SiO2 glass are arranged on the common substrate. The lightwave circuit is configured such that part of output light from the semiconductor laser propagates through a certain length of an optical path, and then is reflected by a reflector and is fed back to the semiconductor laser. Output light from the semiconductor laser and an input waveguide of the lightwave circuit can also be configured to be optically connected directly to each other. The present invention can provide a compact laser device with a narrowed spectral linewidth and stable wavelength controllability.

Abstract: The inventive concepts disclosed and/or claimed herein relate generally to catalysts and, more particularly, but not by way of limitation, to a heterogeneous, metal-free hydrogenation catalyst containing frustrated Lewis pairs. In one non-limiting embodiment, the heterogeneous, metal-free catalyst comprises hexagonal boron nitride (h-BN) having frustrated Lewis pairs therein.