Abstract: An integral optical resonant cavity for frequency conversion is provided. The integral optical resonant cavity includes: a housing, a cavity-length adjustment device, a temperature control device and a nonlinear crystal provided in the temperature control device; a first plano-concave mirror and a second plano-concave mirror included in the cavity-length adjustment device and a nonlinear crystal form the optical resonant cavity; and light passes through the first plano-concave mirror, the nonlinear crystal and the second plano-concave mirror sequentially. The stability of the length of the optical resonant cavity is improved through an integral design thereof, and the stability of the temperature of the nonlinear crystal in the integral optical resonant cavity is improved through the temperature control device, thereby stably controlling relative phases between light fields for the frequency conversion in the resonant cavity.

Abstract: Articles including a solid porous material having a selenium nanomaterial bound to a surface of and within the solid porous material. The article may be a include no polymeric stabilizer or proteinaceous stabilizer. The solid porous material may be a sponge, a film, a fabric, a non-woven material, or a metal-organic framework (MOF), or a combination thereof. The article may be produced by treating a solid porous material with an aqueous selenous acid solution and heating the solid porous material to form the selenium nanomaterial on the surface of and within the solid porous material.

Abstract: A system and method for colorimetric calibration is described herein. A system for performing color calibration is described, comprising at least one broad spectrum light emitting diode, at least one light diffuser plate, at least one interference filter, and a camera, the camera comprising at least one sensor for detection of colors, wherein a spectral response within 5% error of a ground truth method can be achieved. A method for performing color calibration is described, comprising transmitting light from at least one broad spectrum light emitting diode, scattering light with at least one light diffuser plate, filtering light with at least one interference filter, detecting light at a camera sensor, mapping an intensity value for each pixel of the camera sensor, and creating a quantum efficiency curve for each of red, green, and blue channels.

Abstract: A test apparatus or system for testing impact induced brain trauma a method of making and a method using the same are provided. The system includes a head model, which includes a skull component, a brain component, and a fluid component. The skull component has a wall defining an interior chamber. The brain component includes a gel material and is disposed within the interior chamber. The fluid component is disposed inside the interior chamber. The system may also include a fluid tank fluidly coupled with the skull component and configured to provide the fluid component into the interior chamber. The head model may further include a layer of porous media disposed between the brain component and the interior wall surface of the skull component. The system may include at least one impact element for providing an impact on the head model. The impact is translational or rotational or both.

Abstract: Disclosed are an electrolyte solution and an additive thereof, which may improve electrochemical properties of a lithium secondary battery.

Abstract: A electrically conductive hydrogel composition includes: a polar polymer selected from the group consisting of polyvinyl alcohol, polyacrylic acid, polyethylene oxide, poly(2-acrylamido-2-methyl-1-propane sulfonic acid), and combinations thereof; a gelatin; a binding agent including tannic acid and dopamine; a hygroscopic agent including ethylene glycol; a strong electrolyte; and water. A self-healing electrically conductive hydrogel prepared from the electrically conductive hydrogel composition is also provided. A hydrogel-based triboelectric nanogenerator including a self-healing electrically conductive hydrogel film that is made from the self-healing electrically conductive hydrogel is also provided.

Abstract: Herein discloses a method of carbonating reactive magnesia cement, which includes: (i) providing an aqueous suspension including a carbon dioxide-producing bacteria; (ii) mixing the aqueous suspension with a precursor which the carbon dioxide-producing bacteria generates carbon dioxide from for a duration to form an aqueous mixture sufficient for substantially carbonating the reactive magnesia cement; (iii) mixing the aqueous mixture with the reactive magnesia cement to form a blend; wherein a nutrient is provided in the aqueous suspension of step (i) or in the reactive magnesia cement of step (iii) to sustain the carbon dioxide-producing bacteria in the reactive magnesia cement; and (iv) curing the blend to carbonate the reactive magnesia cement. A reactive magnesia cement composite formed by the method is also disclosed.

Abstract: The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure further provides site-specific modifying polypeptides. The present disclosure further provides methods of site-specific modification of a target DNA and/or a polypeptide associated with the target DNA The present disclosure provides methods of modulating transcription of a target nucleic acid in a target cell, generally involving contacting the target nucleic acid with an enzymatically inactive Cas9 polypeptide and a DNA-targeting RNA. Kits and compositions for carrying out the methods are also provided. The present disclosure provides genetically modified cells that produce Cas9; and Cas9 transgenic non-human multicellular organisms.

Abstract: The present invention relates to modified proteins e.g. oxygen-carrying proteins, with improved or enhanced, in comparison to a reference protein, reduction of a metal ion associated with the modified protein. The present invention also relates to methods of using such modified proteins and compositions comprising such proteins e.g. in therapy.

Abstract: An improved carrier frequency offset synchronization method for the VDE-TER system includes matching and filtering the data at a receiver of the system, extracting a training sequence from an information data segment after matching and filtering; performing a carrier frequency offset estimation based on the training sequence to obtain a frequency offset estimated value; based on the frequency offset estimated value, performing a frequency offset compensation on the information data segment to obtain a first-level compensation data segment; performing a phase tracking on the first-level compensation data segment to obtain a cumulative phase compensation value, thereby obtaining a second-level compensation data segment; and demodulating the second-level compensation data segment to obtain the received information after synchronization.

Abstract: The present disclosure belongs to the field of radio frequency circuit design, and in particular relates to a M×N millimeter wave and terahertz planar dipole end-fire array antenna. The M×N millimeter wave and terahertz planar dipole end-fire array antenna is composed of M paths of N× end-fire linear array antennas arranged at equal intervals, and the distance d between two adjacent N× end-fire linear array antennas is less than ?, where ? is the wavelength, and both M and N are integers greater than 1. By connecting linear type feed networks of the M paths of N× end-fire linear array antennas to M-path in-phase radio frequency signal transmitter and controlling the distance between two adjacent N× end-fire linear array antennas to be less than the effective wavelength, a higher gain and a higher half-power width can be realized, and the power consumption of the transmitter can be reduced.

Abstract: A file fragmentation removal method includes collecting input/output system call information of a plurality of file input/output system calls by an application of at least one target file used by an application operating on an arbitrary filesystem, generating a file range list of items comprising information on a start point, an end point, and an access count of input/output based on the input/output system call information, selecting a plurality of fragmentation target items based on the file range list and a predetermined threshold, and selectively removing fragmentation based on whether individual items of the plurality of fragmentation target items are fragmented.

Abstract: Disclosed is a method, device, and system for testing the static contact angle of reagent asphalt, the method includes the following steps: acquiring a side image of a stable droplet formed by a test reagent on asphalt surface, and determining the position of a baseline in the side image; cropping the side image to obtain a droplet image, and extracting droplet contour points in the droplet image; screening out effective contour points corresponding to contours of the two sides of the droplet from the droplet contour points; performing cubic polynomial fitting on the effective contour points to obtain curve function of contour curves on both sides; calculating contact angle value from the curve function and the position of the baseline. The beneficial effects of this disclosure are: this disclosure reduces the difficulty of fitting of the droplet contour and thus improves the calculation precision of the contact angle.

Abstract: A retraction device, e.g., a programmable stiffness state tissue displacement device, for providing increased visibility during an operation is provided. The device includes one or more strips of compliant jammable layer components connected in parallel, and encapsulated within a flexible envelope such that each of the one or more strips of compliant jammable layer components are pneumatically connected. The device further includes a negative pressure pump coupled to the flexible envelope, such that the application of negative pressure to the flexible envelope by the negative pressure pump causes the one or more strips of compliant jammable layer components to jam and thereby transition the retraction device from a malleable state to a rigid state.

Abstract: The present disclosure provides ?2?-1 C-terminal domain mimetics for the treatment of pain, epilepsy or other disorders in a subject. Further provided is an ?2?-1 C-terminal domain peptide which blocks binding of ?2?-1 to the glutamate receptors NMDAR and AMPAR.

Abstract: This disclosure presents systems, devices, and methods that use magnetometers to measure large magnetic moments with strong magnetic anisotropy. A torque magnetometer may include an actuator driven by a motor, a load cell coupled to the actuator, a rotatable spool having a platform configured to hold a sample of a superconductor material, where the rotatable spool is coupled to the load cell by a first line, a pulley, and a second line extending between the rotatable spool and a counterweight, where the second line is positioned on the pulley. Movement of the actuator may cause the rotatable spool to rotate an angle of the platform relative to a magnetic field about the rotatable spool, and the load cell is capable of measuring the tension on the first line.

Abstract: A method of treating impaired lymphatic function in a subject is provided. The method includes a step of inducing activation of Piezo1 ion channels in lymphatic tissues of a subject having impaired lymphatic function. Similarly, a method of treating ocular hypertension or glaucoma in a subject includes a step of inducing activation of Piezo1 ion channels in an eye of a subject having an ocular pressure that is greater than 22 mm Hg. Finally, a method of treating ocular hypertension or glaucoma in a subject includes a step of inducing activation of Piezo1 ion channels in an eye of a subject having an ocular pressure that is greater than 22 mm Hg.

Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a provided lipid prodrug or a pharmaceutical composition thereof.

Abstract: A space-air-ground integrated UAV-assisted IoT data collection method based on AoI comprises: constructing a UAV-assisted space-air-ground integrated IoT system, constructing a UAV channel model and an AoI model, establishing an AoI-based UAV-assisted space-air-ground integrated IoT data collection model, transforming a problem into a Markov problem, introducing a neural network to solve a high-dimensional state problem, introducing a deep reinforcement learning algorithm to train UAVs to find optimal collection points, and introducing a matching theory to match the UAVs and IoT devices.

Abstract: A medical instrument in which an inorganic salt solid such as apatite into which a peptide hormone or the like is embedded is placed so that a metal or the like is coated therewith, in which the inorganic salt solid is provided by controlled delay co-precipitation or the like in an unstable supersaturated calcium phosphate solution, and the medical instrument is exposed to ionizing radiation at a dose sufficient for sterilization.