Abstract: The disclosure provides methods of treating a condition of the retina by administering an inhibitor of connexin 36 and/or an inhibitor of connexin 45 to a subject with a retinal condition. This disclosure further provides compositions for the treatment of a retinal condition which include an inhibitor of connexin 36 and/or an inhibitor of connexin 45.
Type:
Grant
Filed:
August 28, 2017
Date of Patent:
December 31, 2024
Assignee:
The Research Foundation for The State University of New York
Abstract: A system is configured for receiving force data including at least one value indicating the amount of the force applied to the portion of the user and at least one value indicating a direction of the force applied to the portion of the user; obtaining mapping data specifying at least one relation between values of force applied to the portion of the user and changes in a functional responsiveness, functional and/or structural integrity, or both the functional responsiveness and the functional and/or structural integrity of the brain at one or more locations in the brain; estimating, based on the mapping data and the force data, an amount of force loading at one or more particular locations in the brain; and generating, based on the estimating, output data representing an amount of the damage to the brain at the one or more particular locations in the brain.
Abstract: Methods and systems are provided for measuring anatomical dimensions from a single two-dimensional (2D) digital image. The digital image is taken from the front/anterior view using a mobile, handheld communication device. The linear measurements are used to estimate the body volume of the individual. Total body density is calculated from estimated body volume and body weight. Body composition (fat mass and fat-free mass) of the individual is derived from density using known mathematical conversion formulas. A method for estimating body composition analysis is provided. Systems and methods are provided that determine an individual's fitness by determining body composition of the individual using a picture of the individual, determining the individual's VO2 max based on the individual's movement (e.g., walking and/or running a measured distance over a measured amount of time), and determining the individual's fitness based on the body composition and the determined VO2 max.
Type:
Grant
Filed:
March 11, 2022
Date of Patent:
December 31, 2024
Assignee:
The Board of Trustees of The University of Alabama
Abstract: A construction platform that is freely movable up and down is provided, which includes several curved platforms, several columns and a control panel. The curved platforms are connected with one after the other to form a ring-shaped platform that surrounds a cylindrical building and is movable along the columns. Each curved platform is provided with one or more mounting brackets. Each mounting bracket is provided with one or more movable brackets, one or more pressing mechanisms, one or more locking mechanisms, one or more movable rods, one or more suction cups, a pumping mechanism, and one or more emergency braking mechanisms. Each emergency braking mechanism includes a sprocket, a chain, a counterweight, an angle sensor, and a configuring assembly. Each configuring assembly includes a ring gear, a mounting sleeve, a configuring rod, a pawl, a torsion spring, an electromagnet and a magnetic block.
Type:
Grant
Filed:
May 21, 2024
Date of Patent:
December 31, 2024
Assignees:
Hainan University, China National Chemical Engineering No. 13 Construction Co., Ltd.
Abstract: This disclosure relates to non-naturally occurring light reflecting or color changing materials comprising a segmented array of flexible polymers, wherein the segmented array of flexible polymers comprise photonic crystal lattices embedded therein, wherein the segmented array of flexible polymers are themselves embedded within an elastic supporting polymer that maintains a near constant size during chromatic shifting of the photonic crystal lattices.
Abstract: A system for monitoring potential damage to a tissue within a patient caused by tissue retraction during a surgical procedure, the system comprising: a housing body; an attachment mechanism for attaching the housing body to a tip of a surgical retractor; a force sensor; an inertial sensor; a feedback module; and a control module configured to: track force applied by the retractor tip to the tissue based on force signals received from the force sensor; detect the force applied approaching a force threshold, the force threshold based on a relationship between force applied by the retractor tip to the tissue and orientation of the retractor tip against the tissue; in response to the force applied approaching the force threshold, generating a first warning prompt indicating a possibility of damage to the tissue; and outputting the first warning prompt via a feedback module.
Type:
Grant
Filed:
March 18, 2021
Date of Patent:
December 31, 2024
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Inventors:
Derek F. Amanatullah, Hunter Storaci, Andrew Barrett, Harsh Shah
Abstract: A cage culture platform for comprehensively utilizing new marine energy is provided, which includes a wave power generation device, a platform main body, solar power generation devices, a wind power generation device, a culture cage and a mooring system. The wave power generation device is arranged around the platform main body, the solar power generation devices and the wind power generation device are arranged at an upper part of the platform main body, and the culture cage is arranged below the platform main body under water.
Abstract: An electronic device according to an example embodiment includes a processor, and a memory operatively connected to the processor and including instructions executable by the processor, wherein when the instructions are executed, the processor is configured to collect an EEG signal measuring brain activity and an fNIRS signal measuring the brain activity, and output a result of determining a type of the brain activity from a trained neural network model using the EEG signal and the fNIRS signal, and the neural network model may be trained to, extract an EEG feature from the EEG signal, extract an fNIRS feature from the fNIRS signal, extract a fusion feature based on the EEG signal and the fNIRS signal, and output the result of determining the type of the brain activity based on the EEG feature and the fusion feature.
Type:
Grant
Filed:
October 27, 2022
Date of Patent:
December 31, 2024
Assignee:
Foundation for Research and Business, Seoul National University of Science and Technology
Abstract: In one aspect, organic-inorganic nanoparticle compositions are described herein comprising engineered surfaces which, in some embodiments, reduce non-radiative recombination mechanisms, thereby providing optoelectronic devices with enhanced efficiencies. In some embodiments, a nanoparticle composition comprises a layer of organic-inorganic perovskite nanocrystals, the organic-inorganic perovskite nanocrystals comprising surfaces associated with growth passivation ligands and trap passivation ligands, wherein the growth passivation ligands are larger than the trap passivation ligands and are of size unable to incorporate into octahedral corner sites of the perovskite crystal structure.
Abstract: A novel method for using the widely-used electroencephalography (EEG) systems to detect and localize silences in the brain is disclosed. The method detects the absence of electrophysiological signals, or neural silences, using noninvasive scalp electroencephalography (EEG) signals. This method can also be used for reduced activity localization, activity level mapping throughout the brain, as well as mapping activity levels in different frequency bands. By accounting for the contributions of different sources to the power of the recorded signals and using a hemispheric baseline approach and a convex spectral clustering framework, the method permits rapid detection and localization of regions of silence in the brain using a relatively small amount of EEG data.
Abstract: A system and method to control the Na/K pumps for the treatment or prevention of muscle fatigue by applying a synchronization modulation electric field that is effective in synchronizing the Na/K pumps down to individual steps throughout the pumping cycle, thereby synthesizing one ATP for each pumping cycle. The generated ATP molecule compensates the ATP consumed in extrusion of 3 Na ions and pumping 2 K ions such that the net-consumption of ATP for the Na/K pumps controlled by the system and method of the present invention is significantly reduced, theoretically to zero, thereby providing an effective treatment for muscle fatigue.
Type:
Grant
Filed:
March 17, 2022
Date of Patent:
December 31, 2024
Assignee:
University of South Florida
Inventors:
Wei Chen, Jason Edward Mast, Pengfei Liang
Abstract: A rotor cooling structure includes a turbine blower structure provided on first and second sides of a rotor for an induction motor; a refrigerant passage including a plurality of refrigerant passage inlet openings provided on a bottom surface of the turbine blower structure and a plurality of refrigerant passage outlet openings provided at an axial center of the rotor, which fluidically communicates with the refrigerant passage inlet openings and the refrigerant passage outlet openings and is provided along conductor bars of the rotor; and a plurality of micro groove patterns that hold the refrigerant passage outlet openings and are provided on both axial sides of the rotor on an external periphery of the rotor.
Type:
Grant
Filed:
June 21, 2022
Date of Patent:
December 31, 2024
Assignees:
Hyundai Motor Company, Kia Corporation, IUCF-HYU (Industry-University Cooperation Foundation Hanyang University)
Inventors:
Jin Ho Choi, Jong Seok Lee, Sang Jin Park, Sung Woo Hwang, Jae Hyun Kim, Myung Seop Lim
Abstract: Metal halide perovskite crystals, composite materials that include metal halide perovskite crystals and a polymeric matrix material, devices that include metal halide perovskite crystals, and methods of forming metal halide perovskite crystals, composite materials, and devices. The devices may include optoelectronic devices, such as light-emitting diodes. The light-emitting diodes may emit red light.
Type:
Grant
Filed:
July 20, 2021
Date of Patent:
December 31, 2024
Assignee:
The Florida State University Research Foundation, Inc.
Abstract: A multiplex transmission method and apparatus in a multi-link wireless LAN are disclosed. An operating method of a first device comprises the steps of: setting a first link linked with a second device and a first service; setting a second link linked with the second device and a second service; and performing communication with the second device by using the first link and/or the second link. Therefore, the performance of a communication system can be improved.
Type:
Grant
Filed:
July 2, 2020
Date of Patent:
December 31, 2024
Assignees:
Hyundai Motor Company, Kia Corporation, Korea National University of Transportation Industry-Academic Cooperation Foundation
Abstract: Methods of and systems for making a hyperpolarized fluid are provided, which include exposing a fluid and parahydrogen to a catalyst. The hyperpolarized fluid can be introduced to a subject. The hyperpolarized fluid can be included in methods of imaging a subject. Also provided are methods that use the hyperpolarized fluids for detecting protein ligand interactions and for enhancing the NMR signals of biopolymers having chemically exchangeable protons.
Type:
Grant
Filed:
October 5, 2018
Date of Patent:
December 31, 2024
Assignee:
University of Florida Research Foundation, INC.
Abstract: Among the various aspects of the present disclosure is the provision of compositions and methods for mapping transposon insertions. Applications can include mapping the locations of self-reporting transposons (SRTs) from thousands of single cells in parallel, while simultaneously measuring mRNA abundance from the same single cells; analyzing genome-associated protein (GAP) (e.g., transcription factor) binding/interactions in a small number of cells in bulk, without single cell resolution; lineage tracing; or as an improved readout for transposon mutagenesis screens.
Type:
Grant
Filed:
December 11, 2019
Date of Patent:
December 31, 2024
Assignee:
Washington University
Inventors:
Robi D. Mitra, Arnav Moudgil, Michael Nathaniel Wilkinson, Zongtai Qi
Abstract: A system and devices provide for accurate localization of orthopedic implants based on magnetic tracking approach (MTA) technology and without radiation. The system includes at least one magnetic beacon that is joined to an orthopedic screw/implant fixed to a patient's spine. A detector in the form of a magnetic sensor array detects the magnetic field from the beacon and produces an electrical signal in response thereto. A computer using a multi-objective magnetic location algorithm tracks the spatial position and movement of the beacon based on the electrical signal, and hence tracks the patient's spine.
Abstract: A method of pretreating wastewater sludge including applying an amount of at least 0.01 g/g TSS Ca(ClO)2 to wastewater sludge to enhance digestibility of the sludge and reduce phosphorus concentration therein and then allowing sufficient time for the wastewater sludge to densify to a treated sludge having a specific resistance to filtration (SRF) of 3 to 4 (1010 m/Kg). The resulting treated sludge composition being sterilized, free of harmful bacteria, and useful as a fertilizer, particularly for growing mushrooms.
Type:
Application
Filed:
July 22, 2022
Publication date:
December 26, 2024
Applicant:
The Governors of the University of Alberta
Inventors:
Liu Yang, Najiaowa Yu, Lei Zhang, Anqi Mou, Huijuan Sun, Abdulnayeem Mohammed
Abstract: Flushable wet wipes, and methods of making and using the same, are described. The flushable wet wipes include a biopolymer comprising a carrageenan and optionally a monovalent or multivalent salt on a substrate.
Type:
Application
Filed:
June 18, 2024
Publication date:
December 26, 2024
Applicant:
The University of Toledo
Inventors:
Yakov Lapitsky, Kunal Choudhuri, Umberto A. Kober
Abstract: A high-impedance fault positioning method and system based on synchronous Lissajous curve characteristics are provided. The method includes: acquiring a bus zero-sequence differential voltage and a feeder zero-sequence current of a faulty line; constructing a first Lissajous curve in a characteristic frequency band range based on the bus zero-sequence differential voltage and the feeder zero-sequence current; when the proportion of the faulty line is less than a set threshold value and the slope of the first Lissajous curve is negative, determining that high-impedance faults have occurred in the faulty line; constructing a second Lissajous curve based on the bus zero-sequence differential voltage and the section zero-sequence current, performing linear fitting on discrete data points of the second Lissajous curve to obtain a fitted curve; and when the slope of the fitted curve is negative for at least three consecutive periods, determining that high-impedance faults have occurred in the section.