Abstract: A light emitting diode includes a substrate, a first semiconductor layer, an active layer, a second semiconductor layer, a first electrode, a second electrode and a carbon nanotube structure. The first semiconductor layer, the active layer, and the second semiconductor layer are stacked on the substrate. The first semiconductor layer is a stepped structure and has a first surface and a second surface lower than the first surface. The first electrode is located on and electrically connected to the second semiconductor layer. The carbon nanotube structure is located on the second surface of the first semiconductor layer and electrically connected to the first semiconductor layer. The second electrode is located on and electrically connected to the carbon nanotube structure.

Abstract: An ultrasonic device evaluates the sound velocity of a nail to determine the overall health of a patient and to monitor cosmetological effects of certain products on the nail. The ultrasonic device includes a handhold probe having an piezoelectric transducer encased in cover that emits high-frequency ultrasonic impulses directed towards the nail. The nail reflects returning ultrasonic echoes back to the piezoelectric transducer. The returning ultrasonic echoes vibrate the piezoelectric transducer. A processor of a computer converts the vibrations into electrical pulses. The processor evaluates amplitude values of the electrical pulses to determine the parameters of the human nail, including the thickness, density and elasticity. The parameters are displayed on a display and analyzed by a technician to determine the nail condition. The health of the person or the effect of products on the nail can be determined based on the nail parameters.

Abstract: A system and method involves detecting operational social disruptive events on a global scale, assigning disease or non-disease event staging and warnings to express data in more simplistic terms, modeling data in conjunction with linguistics analysis to establish responsive actions, generating visualization and modeling capabilities for communicating information, and modeling disease or non-disease propagation for containment and forecasting purposes.

Abstract: A video game in possession of and/or in the proximity of a patient. The patient computing system receives an indication that it is to begin a game, and executes the game using identified game parameters that are associated with the patient by a clinician as part of a disease therapy program. As the game executes, game state progresses in response to physical activity of the patient, causing the patient to exercise. The physical activity is received as input into the patient computing system. Such input causes game state to be progressed dependent on the identified game parameters that are associated with the game. Thus, the game is tailored for the patient by a clinician in order to motivate physical activity that is medically beneficial to the patient in order to advance through the disease therapy program.

Abstract: The disclosure provides for dendronized polymers, and the use of the polymers as carriers for the intracellular delivery of nucleic acids.

Abstract: A semiconductor device production method where separate semiconductor chips are stacked on a semiconductor substrate having a main surface on which multiple semiconductor chips including semiconductor integrated circuits are formed, the semiconductor chips in different layers are connected to each other to enable signal transmission, and a structure formed thereby is separated into multiple stacks of the semiconductor chips. The method includes a first step of forming an insulating layer on the main surface of the semiconductor substrate; a second step of stacking the separate semiconductor chips, which include the integrated semiconductor circuits on main surfaces thereof, via the insulating layer on the semiconductor chips formed on the semiconductor substrate such that opposite surfaces of the separate semiconductor chips opposite to the main surfaces face the insulating layer; and a third step of forming connecting parts that enable signal transmission between the semiconductor chips in different layers.

Abstract: A system for performing non-invasive networked medical procedures including a number of in vivo medical devices, a communication path between at least two of the devices, an ex vivo control unit to control the behavior of the devices, and a wireless communication path between the control unit and at least one of the devices. An associated method for performing non-invasive networked medical procedures is also provided. Further included is a simulation method that utilizes accurate electromagnetic field simulations, using a software based test bench, to determine the maximum allowable transmitted power levels from in vivo devices to achieve a required bit error rates (BER) at an in vivo or ex vivo node (receiver) while maintaining the specific absorption rate (SAR) under a required threshold.

Abstract: The present invention relates to a PVC-based metallopolymer nanocomposite. The PVC-based metallopolymer nanocomposite includes a core-forming metal ion, a nucleophilic thiol having three mercapto functional groups, and poly(vinyl chloride) (PVC). The present invention also relates to a metallopolymer nanocomposite surface modified with silica that is prepared by grafting the PVC-based metallopolymer nanocomposite with a silane compound.

Abstract: Circular nucleic acid vectors that provide for persistently high levels of protein expression are provided. The circular vectors of the subject invention are characterized by being devoid of expression-silencing bacterial sequences, where in many embodiments the subject vectors include a unidirectional site-specific recombination product hybrid sequence in addition to an expression cassette. Also provided are methods of using the subject vectors for introduction of a nucleic acid, e.g., an expression cassette, into a target cell, as well as preparations for use in practicing such methods. The subject methods and compositions find use in a variety of different applications, including both research and therapeutic applications. Also provided is a highly efficient and readily scalable method for producing the vectors employed in the subject methods, as well as reagents and kits/systems for practicing the same.

Abstract: The present invention provides methods, compositions and kits for the detection of Parkinson' disease (PD) diagnostic biomarkers, for the diagnosis of PD, for the identification of a subject at risk for developing PD, and for the generation of patient-specific PD diagnostic biomarker profiles.

Abstract: Improved structural column assemblies and related fabrication methods are provided. More particularly, the present disclosure provides improved systems/methods for the design and fabrication of structural column assemblies having improved mechanical properties and/or improved resistance to multiple hazards (e.g., earthquakes, blasts, high temperatures, etc.). Disclosed herein is a structural column assembly having a uniquely designed fiber reinforced polymer (FRP) tube filled with concrete to be used as a structural column (e.g., in bridge and/or building construction). The exemplary composite or FRP tube can include layers of metallic and/or non-metallic fibers wound at improved/optimized angles. A multi-hazard resilient column system which can negate the need for additional concrete reinforcement or formwork at construction sites is provided.

Abstract: A particle accelerator is provided that includes a piezoelectric accelerator element, where the piezoelectric accelerator element includes a hollow cylindrical shape, and an input transducer, where the input transducer is disposed to provide an input signal to the piezoelectric accelerator element, where the input signal induces a mechanical excitation of the piezoelectric accelerator element, where the mechanical excitation is capable of generating a piezoelectric electric field proximal to an axis of the cylindrical shape, where the piezoelectric accelerator is configured to accelerate a charged particle longitudinally along the axis of the cylindrical shape according to the piezoelectric electric field.

Abstract: The present invention relates to a method and system for determining location and position for the effective use thereof in a location-based service by precisely determining information on the location and position of a user terminal, such as a smartphone, to provide the determined location and position to the user terminal using a georeferenced reference image DB preconstructed on a server on a network or on the user terminal, and images captured by a camera of the user terminal.

Abstract: An optical device including a shaped electrode on a substrate thereof utilizes total internal reflection to provide improved transmission of electromagnetic radiation (‘light’) to the substrate compared to standard electrode designs that involve flat electrode surfaces. Redirection of incident light by a tilted or otherwise shaped contact or material added on the contact provides otherwise reflected light to an open surface region of the substrate. Optional plasmon mediated focusing of incident p-polarized light may be realized.

Abstract: A device, method, and computer-readable medium for correcting at least one error in readings of electricity meters, the method including receiving first readings of regular meters measuring electric energy delivered in each of a group of cables fed from a same distribution node in an electric grid during a period of time, receiving second readings of check meters measuring electric energy delivered in each of combinations of cables in the group of cables during the period of time, the combinations of cables being formed based on a redundant matrix in a generator matrix of a linear systematic block code, and correcting, in response to determining that at least one error been detected, the at least one error in the first readings of the regular meters and the second readings of the check meters.

Abstract: This invention provides a method of treating lung cancer including administering a therapeutically effective amount of a compound of 0089-0022 formula I to a subject in need thereof. The compound activates pyruvate kinase M2 isoform (PKM2) to treat the lung cancer. In one example, the lung cancer is Non-Small Cell Lung Cancer (NSCLC).

Abstract: Methods and kits for identifying neurological conditions in a patient by determining a level of expression of dynactin subunit p62 are disclosed. The neurological conditions may include, for example, Alzheimer's Disease (AD) without cerebral amyloid angiopathy (CAA).

Abstract: The present invention provides methods of making and using peripherally restricted inhibitors of fatty acid amide hydrolase (FAAH). The present invention provides compounds and compositions that suppress FAAH activity and increases anandamide levels outside the central nervous system (CNS). The present invention also sets forth methods for inhibiting FAAH as well as methods for treating conditions such as, but not limited to, pain, inflammation, immune disorders, dermatitis, mucositis, the over reactivity of peripheral sensory neurons, neurodermatitis, and an overactive bladder. Accordingly, the invention also provides compounds, methods, and pharmaceutical compositions for treating conditions in which the selective inhibition of peripheral FAAH (as opposed to CNS FAAH) would be of benefit.

Abstract: A magnetic resonance system (10), and corresponding method, image a subject using a conversion-free interleaved black and bright blood imaging (cfIBBI) sequence. A MR scanner (12) is controlled to perform a plurality of repetitions of a black blood imaging sequence (52). The black blood imaging sequence (52) includes a tissue nulling sub-sequence followed by a black blood acquisition sub-sequence (56) performed a time interval (TI) after the tissue nulling sub-sequence. The MR scanner (12) is further controlled to, between successive repetitions of the black blood imaging sequence (52), perform a bright blood imaging sequence (54) including the tissue nulling sub-sequence followed by a bright blood acquisition sub-sequence (58) performed the time interval (TI) after the tissue nulling sub-sequence. The time intervals (TI) of the black blood imaging sequence (52) and the bright blood imaging sequence (54) are of the same duration.

Abstract: The invention relates generally to methods of treating spasticity, rigidity, or muscular hyperactivity conditions by introducing a portion of an expanded population of neural stem cells into an area of a recipient spinal cord.