Abstract: The present invention generally relates to alcohol-terminated polyisobutylene (PIB) compounds, and to a process for making such compounds. In one embodiment, the present invention relates to primary alcohol-terminated polyisobutylene compounds, and to a process for making such compounds. In still another embodiment, the present invention relates to polyisobutylene compounds that can be used to synthesize polyurethanes, to polyurethane compounds made via the use of such polyisobutylene compounds, and to processes for making such compounds. In yet another embodiment, the present invention relates to primary alcohol-terminated polyisobutylene compounds having two or more primary alcohol termini and to a process for making such compounds. In yet another embodiment, the present invention relates to primary terminated polyisobutylene compounds having two or more primary termini selected from amine groups or methacrylate groups.

Abstract: A compound having a structure according to formula Ir(LA)n(LB)3-n: is described. In the structure of Formula Ir(LA)n(LB)3-n: A1, A2. A3, A4, A5, A6, A7, and A8 are each independently either carbon or nitrogen; at least one of A1, A2, A3, A4, A5, A6, A7, and A8 is nitrogen; ring B is bonded to ring A through a C—C bond; the iridium is bonded to ring A through an Ir—C bond; X is O, S, or Se; R1, R2, R3, and R4 each independently represent no substitution up to the maximum possible substitutions; any adjacent substitutions in R1, R2, R3, and R4 are optionally linked together to form a ring; R1, R2, R3, R4, and R5 are each independently selected from a variety of substituents; and n is 1, 2, or 3. Formulations and devices, such as an OLEDs, that include the compound of Formula Ir(LA)n(LB)3-n are also described.

Abstract: A method of a measuring kinematic parameter in a subject is provided. The method includes obtaining a first magnetic resonance (MR) image set of a bone marrow segment of the subject in a first position and obtaining a second MR image set of the bone marrow segment of the subject in a second position where the second position different from the first position. The method further includes registering the first image set with the second image set and measuring a kinematic parameter.

Abstract: The present invention provides a method and apparatus for tissue, such as an allograft, storage and preservation for extended periods of time at room temperature in a sterile tissue culture chamber. The invention further provides a process for maintaining the sterility of tissue using the apparatus as described.

Abstract: Embodiments of calcium channel agonists, as well as methods of making and using the calcium channel agonists, are disclosed. The disclosed calcium channel agonists and corresponding salt forms have a structure according to general formula I: wherein each bond depicted as “” is a single bond or a double bond as needed to satisfy valence requirements; Z1, Z2, Z3, Z4, and Z5 independently are nitrogen or carbon; R1 and R3 are alkyl; R2 is alkyl, aryl, heteroaryl, arylalkyl, or heteroarylalkyl; and R4 is alkyl or hydroxyalkyl.

Abstract: A compound having a structure according Formula Ir(LA)n(LB)3-n: is described. In the structure of Formula Ir(LA)n(LB)3-n: A1, A2, A3, A4, A5, A6, A7, and A8 are each carbon or nitrogen; at least one of A1, A2, A3, A4, A5, A6, A7, and A8 is nitrogen; ring B is bonded to ring A through a C—C bond; the iridium is bonded to ring A through an Ir—C bond; X is O, S, or Sc; R1, R2, R3, and R4 each independently represent no substitutions up to the maximum possible substitutions; any adjacent substitutions in R1, R2, R3, and R4 are optionally linked together to form a ring; each R1, R2, R3, R4, and R5 is independently selected from a variety of substituents; and n is an integer from 1 to 2. Formulations and devices, such as an OLEDs, that include the compound of Formula Ir(LA)n(LB)3-n are also described.

Abstract: Systems and methods of pulse-echo imaging using stabilized symmetric pulses are described. The systems and methods are based on the development of a class of symmetric, i.e., two sided, functions that can be designed and utilized as stabilized pulses. Stabilized pulses are pulses having stable inverse filters, and have previously only been established for asymmetric functions. The systems and methods described herein can be used for super-resolution pulse-echo imaging, for example super-resolution ultrasound imaging.

Abstract: Disclosed herein is a nutraceutical composition comprising dried Ziziphus mauritiana leaves, dried Lepidium sativum leaves, dried olive leaves at specific weight ratios and a specific amount of olive oil. The disclosed composition has been shown to effectively treat with minimal side effects, the common symptoms of sickle cell disease (SCD) including severe pain, bacterial infection, inflammation, wounds, fever, cough, shortness of breath. Various embodiments of methods of treating SCD patients using the same composition and methods of preparing the composition are also provided.

Abstract: A flash memory apparatus having a physical unclonable function (PUF) and an embodying method of the same are provided. To elaborate, the flash memory apparatus includes a flash memory unit that comprises a main memory area and a peripheral memory area; a challenge input unit that receives input of a challenge value; a read voltage setting unit that sets a read voltage based on the input challenge value; a data reading unit that reads data by applying the read voltage to a memory cell included in a pre-set memory area in the peripheral memory area each time the challenge value is input; and a response output unit that outputs the read data as a response value corresponding to the challenge value, wherein the pre-set memory area consists of a plurality of memory cells comprising two or more memory cells having different threshold voltage values.

Abstract: Disclosed is a compound, or a pharmaceutically acceptable salt or ester thereof, having a structure of: X1-L-X2 wherein L is a linking moiety comprising an enone; and X1 and X2 are each independently an optionally-substituted N-heterocycle. Also disclosed are method for treating pulmonary conditions and other organ or system conditions with the compounds.

Abstract: A photon detection apparatus that includes a photon detector configured to detect single photons. The apparatus includes: a time-to-voltage converter circuit generating a signal proportional to the time interval the photon detector exceeds a reference threshold. Thus, it is the length of time the photon detector exceeds the threshold rather than integrated signal from the photon detector that indicates whether a photon is detected. A second threshold test then discriminates detection events based on the output signal from the time-to-voltage converter.

Abstract: A semiconductor device that includes an optical resonator spaced from a waveguide structure to provide for evanescent-wave optical coupling therebetween. The optical resonator includes a closed loop waveguide defined by a vertical thyristor structure. In one embodiment, the vertical thyristor structure is formed by an epitaxial layer structure including complementary (both an n-type and a p-type) modulation doped quantum well interfaces formed between an N+ region and a P+ region.

Abstract: The present invention relates to inhibitors of Nox1-dependent reactive oxygen species production and their use in the treatment of disorders associated with reactive oxygen species, such as hypertension and cancer.

Abstract: The disclosure concerns compositions containing inactivated but therapeutically active biopharmaceuticals, and methods for formulation thereof. Biopharmaceuticals are encapsulated and immobilized in dry amorphous carbohydrate-glass and irradiated for inactivation while in the dry state. The resulting compositions provide ambient-temperature stable, therapeutically active but inactivated biopharmaceuticals for use in vaccines and other applications.

Abstract: Recombinant attenuated Y. pseudotuberculosis mutants have been created that show efficacy as oral vaccines against plague caused by Y. pestis and Yersinosis caused by both Y. enterocolitica and Y. pseudotuberculosis. Thus, live attenuated Y. pseudotuberculosis-based vaccines can be used to prevent Yersinosis in farm animals such as swine, cattle and sheep. The palatable baits containing live attenuated Y. pseudotuberculosis-based vaccines may be acceptable methods to control plague epidemics in wild animals. The methods disclosed can also be used to generate recombinant attenuated Y. entercolitica and Y. pestis vaccine strains.

Abstract: Provided is a capacitor, which includes a first electrode including aluminum, a second electrode facing the first electrode, and a first dielectric layer interposed between the first electrode and the second electrode, including aluminum oxide, and having multiple pores defined in a surface of the first dielectric layer in contact with the second electrode.

Abstract: Electrocatalysts for the anode electro-oxidation of formic acid in direct formic acid fuel cells (DFAFCs). The Pd-, Pt- or PdPt-based electrocatalysts contain CeO2-modified ordered mesoporous carbon (OMC) as support material. Compositions and ratios of Pd:Pt in the electrocatalysts as well as methods of preparing and characterizing the catalysts and the CeO2-OMC support material.

Abstract: A hydraulic cell stretching device comprising a source of variable pressured hydraulic fluid hydraulically coupled to a flexing chamber. The flexing chamber has at least one cell well. The cell well has a membrane subjected to the variable pressured hydraulic fluid.

Abstract: Disclosed are methods and pharmaceutical compositions for modulating one or more steroidal receptor activities. The methods typically utilize and the pharmaceutical compositions typically include one or more substituted phenyl aziridine precursors, their respective aziridines, analogs thereof, derivatives thereof, or pharmaceutically acceptable salts thereof such as CpdA. The methods and compositions may be used for treating diseases, disorders, and conditions associated with glucocorticoid receptor activity, androgen receptor activity, or both, such as cancers, acne vulgaris, and alopecia.

Abstract: ‘NCPX1’ is a new cultivar of hybrid flowering pear with a narrow fastigiated habit, red to purple flower buds opening with white flower petals and a high level of resistance to fire blight.