Abstract: A portable EEG (electroencephalograph) instrument, especially for use in emergencies and brain assessments in physicians' offices, detects and amplifies brain waves and converts then into digital data for analysis by comparison with data from normal groups. In one embodiment, the EEG electrodes are in a headband which broadcasts the data, by radio or cellular phone, to a local receiver for re-transmission and/or analysis. In another embodiment, the subject is stimulated in two modes, i.e., aural and sensory, at two different frequencies to provide the subject's EPs (Evoked Potentials), assessing transmission through the brainstem and thalamus.
Abstract: A method of treating motor deficits in a stroke patient, comprising assessing a patient's motor deficits, determining therapeutic goals for the patient, based on the patient's motor deficits, selecting therapeutic tasks based on the therapeutic goals, performing each of the selected therapeutic tasks repetitively, observing the performance of the therapeutic tasks, initiating the stimulation of the vagus nerve manually at approximately a predetermined moment during the performance of the therapeutic tasks, stimulating the vagus nerve of the patient during the performance of the selected therapeutic tasks, and improving the patient's motor deficits.
Type:
Grant
Filed:
October 12, 2012
Date of Patent:
April 15, 2014
Assignees:
MicroTransponder, Inc., The Board of Regents, The University of Texas System
Inventors:
Michael P. Kilgard, Navzer Engineer, David Michael Pierce, Robert L. Rennaker
Abstract: The invention relates to micelles that are elaborated with functionality useful for imaging and/or selectively targeting tissue, e.g., in the delivery of hydrophobic agents.
Type:
Grant
Filed:
June 2, 2005
Date of Patent:
April 15, 2014
Assignee:
Case Western Reserve University
Inventors:
Hua Ai, Jeffrey L. Duerk, Chris Flask, Jinming Gao, Jonathan S. Lewin, Xintao Shuai, Brent Weinberg
Abstract: A method of treating gamma oncogenic herpesviruses, in vivo, through use of Delta-9 Tetrahydrocannabinol (THC). THC inhibits KSHV and EBV reactivation as well as inhibiting lytic replication of MHV 68 and HVS in vitro. Specifically, THC inhibits immediate early gene ORF 50 promoter activity.
Type:
Grant
Filed:
September 15, 2005
Date of Patent:
April 15, 2014
Assignee:
University of South Florida
Inventors:
Maria M. Medveczky, Peter G. Medveczky, Tracy Sherwood, Thomas W. Klein, Herman Friedman
Abstract: A method and system for the reduction of pollutant NOx gases from automobile exhaust, as well as a method of reforming hydrocarbons, using a self-sustaining catalyst comprising an ion conductive support, a dispersed cathodic phase, a dispersed anodic phase, and a dispersed sacrificial phase, and a method of forming the self-sustaining catalyst.
Abstract: Disclosed is a tissue-derived biomaterial carrier device (1) comprising a carrier case 810), an arm (125) provided upright on an interior bottom wall surface of the carrier case (10), a mounting part (121), a swing mechanism (122), a temperature control box (20) provided detachably on an exterior wall surface of the carrier case (10), and a heater (201) provided in the temperature control box (20). The mounting part (121) receives the mounting of a housing vessel in which a tissue-derived biomaterial is housed (an opening part (121a)). The swing mechanism (122) swingably supports the mounting part (121) relative to the arm (125). With the temperature control box (20) mounted on the carrier case (10), the heater (201) in the temperature control box (20) receives the supply of electric power from a battery (203) and regulates the temperature within the carrier case (10).
Type:
Grant
Filed:
July 23, 2009
Date of Patent:
April 15, 2014
Assignees:
Kyoto University, Umihira Works Co., Ltd.
Abstract: The present invention includes a cleavable surfactant/detergent compound of the following formula: wherein the variables are defined herein. Embodiments of the cleavable surfactant/detergent compound are useful, for example, in methods for isolating a hydrophobic molecule that include providing a plasma comprising a hydrophobic molecule, applying the cleavable surfactant to the plasma so that the surfactant engages the hydrophobic molecule, cleaving the surfactant from the hydrophobic molecule, and analyzing said hydrophobic molecule.
Type:
Grant
Filed:
November 15, 2010
Date of Patent:
April 15, 2014
Assignee:
Vanderbilt University
Inventors:
Richard M Caprioli, Ned A. Porter, Jeremy L. Norris
Abstract: A wireless detection apparatus includes an antenna, a voltage control oscillator, and a processing unit. The antenna receives a first wireless signal and generates an electrical signal according to the first wireless signal. The first wireless signal is generated by reflecting a second wireless signal from an object under test. The voltage control oscillator is coupled to the antenna to generate an oscillating signal under an interference of the electrical signal. The oscillating signal varies with variation of the electrical signal. The processing unit is coupled to the voltage control oscillator to evaluate a parameter of the object under test according to the variation of the oscillating signal.
Type:
Grant
Filed:
September 20, 2010
Date of Patent:
April 15, 2014
Assignees:
Industrial Technology Research Institute, National Sun Yat-sen University
Inventors:
Tzyy-Sheng Horng, Fu-Kang Wang, Chieh-Hsun Hsiao, Je-Kuan Jau
Abstract: An electromagnetic system having a reaction mass with a field winding embedded therein, a base plate having an inner annular surface and an outer annular surface, and an armature winding coupled to at least a portion of the inner annular surface and at least a portion of the outer annular surface of an upper end portion of the base plate. In operation, directing an electric current in at least one of the field winding and the armature winding causes at least one of the base plate and the reaction mass to move relative to each other. The electromagnetic system can be used for seismic exploration and vibroseis applications, among other uses.
Type:
Grant
Filed:
March 16, 2010
Date of Patent:
April 15, 2014
Assignee:
Board of Regents, The University of Texas System
Inventors:
Ray Zowarka, John Uglum, Jim Upshaw, Charles Penney, Hsing-Pang Liu, Stephen Manifold, Kent Davey, Bryan Bunkowski, David Prater
Abstract: This invention relates to methods for optimizing a golf swing by measuring and providing feedback on a combination of various key parameters of a subject's movement to both generate more power and reduce injury.
Type:
Grant
Filed:
July 27, 2012
Date of Patent:
April 15, 2014
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Inventors:
Jessica Rose, David W. Meister, Amy L. Ladd, Katherine M. Steele
Abstract: The present invention relates to methods for preparing an artificial immune system. The artificial immune system comprises a cell culture comprising T cells, B cells and antigen-primed dendritic cells. The artificial immune system of the present invention can be used for in vitro testing of vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals.
Type:
Grant
Filed:
November 3, 2011
Date of Patent:
April 15, 2014
Assignees:
Sanofi Pasteur VaxDesign Corp., Virginia Commonwealth University
Inventors:
William L. Warren, Donald Drake, III, Janice Moser, Inderpal Singh, Haifeng Song, Eric Mishkin, John G. Tew
Abstract: Compound semiconductor devices and methods of doping compound semiconductors are provided. Embodiments of the invention provide post-deposition (or post-growth) doping of compound semiconductors, enabling nanoscale compound semiconductor devices including diodes and transistors. In one method, a self-limiting monolayer technique with an annealing step is used to form shallow junctions. By forming a sulfur monolayer on a surface of an InAs substrate and performing a thermal annealing to drive the sulfur into the InAs substrate, n-type doping for InAs-based devices can be achieved. The monolayer can be formed by surface chemistry reactions or a gas phase deposition of the dopant. In another method, a gas-phase technique with surface diffusion is used to form doped regions. By performing gas-phase surface diffusion of Zn into InAs, p-type doping for InAs-based devices can be achieved.
Type:
Grant
Filed:
July 26, 2010
Date of Patent:
April 15, 2014
Assignee:
The Regents of the University of California
Inventors:
Ali Javey, Alexandra C. Ford, Johnny C. Ho
Abstract: Prodrug formulations of insulin and insulin analogs are provided wherein the insulin peptide has been modified by an amide bond linkage of a dipeptide prodrug element. The prodrugs disclosed herein have extended half lives of at least 10 hours, and more typically greater than 2 hours, 20 hours and less than 70 hours, and are converted to the active form at physiological conditions through a non-enzymatic reaction driven by chemical instability.
Type:
Grant
Filed:
December 18, 2009
Date of Patent:
April 15, 2014
Assignee:
Indiana University Research and Technology Corporation
Inventors:
Richard D. DiMarchi, Binbin Kou, Shujiang Cheng
Abstract: In accordance with some embodiments, receivers for receiving a wireless data transmission are provided, the receivers comprising at least one amplifier that receives an RF input signal and produces at least one amplified signal; a mixer that mixes the at least one signal to produce a mixed signal; a filter that filters the mixed signal to produce a filtered signal, a comparator that compares the filtered signal to a threshold voltage and produces a digital signal, a first pulse generate i that generates a first pulse in response to a transition in the digital signal, a second pulse generator that generates a second pulse that is longer than the first pulse in response to a transition in the digital signal; and digital logic that generates a clock output and that generates a data output based on a state of the first pulse when the second pulse expires.
Type:
Grant
Filed:
September 28, 2010
Date of Patent:
April 15, 2014
Assignee:
The Trustee of Columbia University in the City of New York
Abstract: Provided are analysis cassettes that include removable sealing layers and deformable connector layers that place various channels, chambers, and reservoirs on the cassettes into fluid communication with one another. The cassettes are suitable for use in self-contained, immunoassay devices that may be operated in an automated fashion. Also disclosed are methods for analyzing samples by use of the disclosed cassettes.
Type:
Grant
Filed:
August 5, 2009
Date of Patent:
April 15, 2014
Assignee:
The Trustees Of The University Of Pennsylvania
Abstract: A magnetic oxide-quantum dot nanocomposite and methods of synthesizing it. In one embodiment, the magnetic oxide-quantum dot nanocomposite has at least one magnetic oxide nanoparticle coated with a silica (SiO2) shell and terminated with at least one thiol group (—SH), and at least one CdSe/ZnS quantum dot linked with the at least one SiO2-coated magnetic oxide nanoparticle via the at least one thiol group. In one embodiment, the at least one magnetic oxide nanoparticle comprises at least one iron oxide (Fe3O4) nanoparticle.
Type:
Grant
Filed:
March 25, 2011
Date of Patent:
April 15, 2014
Assignee:
Board of Trustees of The University of Arkansas
Inventors:
Alexandru S. Biris, Yang Xu, Daoyuan Wang
Abstract: The present invention relates to agents that find use in the treatment, management, and/or study of cancer. In particular, the present invention relates to agents (e.g., small molecules, nucleic acids) that affect MMSET expression or activity.
Type:
Grant
Filed:
February 11, 2011
Date of Patent:
April 15, 2014
Assignee:
The Regents of The University of Michigan
Inventors:
Arul M. Chinnaiyan, Sooryanaryana Lnu, Qi Cao, Irfan Asangani
Abstract: Organoboron compounds are described that upon exposure to light absorb light and isomerize and form a dark-colored isomer. The dark-colored isomer converts back to the colorless isomer upon removal of light, or exposure to oxygen or heat. Such compounds can be added into polymeric matrices such as films. These compounds are suitable for UV-blocking, UV-detecting, and for oxygen-sensing applications. Uses include UV-blocking windows, sunglasses, and as indicators in packaging such as food packaging.
Type:
Grant
Filed:
March 29, 2012
Date of Patent:
April 15, 2014
Assignee:
Queen's University at Kingston
Inventors:
Suning Wang, Hazem Y. S. Amarne, Yingli Rao
Abstract: A cell/particle analyzing device includes a light-emitting unit, a light-diverting unit, a first receiving unit and a second receiving unit. The light-emitting unit generates a first light beam. The light-diverting unit is connected to the light-emitting unit and has an input end, a bidirectional transceiving end and an output end. The input end receives the first light beam generated by the light-emitting unit. The bidirectional transceiving end transmits the first light beam generated by the light-emitting unit and receives a second light beam. The output end outputs the second light beam. The first receiving unit is connected to the output end of the light-diverting unit and receives the second light beam. The second receiving unit is aligned with the bidirectional transceiving end.
Type:
Grant
Filed:
December 12, 2011
Date of Patent:
April 15, 2014
Assignee:
National Pingtung University of Science and Technology
Abstract: A surgical robot including an imaging system comprising at least one camera, a processor in communication with the imaging system, a manipulation system in communication with the processor, and a visual display in communication with the processor. The processor is operable to calculate a stiffness estimate for an area of an environment based on an environment model of tool-environment interaction data, create a composite image comprising a stiffness map of the stiffness estimate overlaid on an environment image from the at least one camera, and output the composite image on the visual display.
Type:
Grant
Filed:
October 20, 2009
Date of Patent:
April 15, 2014
Assignee:
The Johns Hopkins University
Inventors:
Allison Mariko Okamura, Tomonori Yamamoto, Peter Balazs Vagvolgyi