Abstract: The present invention relates to pregnancy hormone combinations and methods of treatment for autoimmune diseases having at least two hormonal components, a pregnancy hormone (such as estriol), and a gestagen (such as levonorgestrel or norethindrone) thereby providing for the continuous, uninterrupted administration of pregnancy hormones for the treatment for autoimmune disorders, such as multiple sclerosis.
Type:
Grant
Filed:
June 4, 2008
Date of Patent:
February 25, 2014
Assignee:
The Regents of the University of California
Abstract: A bone cement composition which contains titanium dioxide particles having a median diameter of 0.5 to 7.0 ?m as measured by a laser diffraction/scattering particle size distribution analyzer and a BET specific surface area of 0.5 to 7.0 m2/g as measured by a nitrogen adsorption method, and a base-forming component comprising a (meth)acrylate polymer and a (meth)acrylate monomer, wherein the content of the titanium dioxide particles is 5 to 50% by mass based on the total mass of the composition. The bone cement composition has bioactivity and is capable of forming a hardened material having a high mechanical strength.
Abstract: Physician interactive workstations with global voxel distribution visualization may also include one or more of a 3-D color scale image of a population of voxel in target regions, organs or systems. The workstation may be configured to evaluate intensity or other measures of voxels of patient images associated with tissue for early detection of a global injury.
Type:
Grant
Filed:
December 9, 2011
Date of Patent:
February 25, 2014
Assignee:
Wake Forest University Health Sciences
Inventors:
William Gregory Hundley, Craig A. Hamilton, Ralph B. D'Agostino
Abstract: Methods for detecting an infection with Mycobacterium tuberculosis (Mtb) in a subject are disclosed, wherein the subject is a child, a subject with a latent Mycobacterium tuberculosis infection. Method are also disclose for detecting an extra-pulmonary Mycobacterium tuberculosis infection in a subject. The methods include detecting the presence of CD8+ T cells that specifically recognize an Mtb polypeptide. The methods include in vitro assays for detecting the presence of CD8+ T cells in a biological sample.
Type:
Grant
Filed:
September 22, 2009
Date of Patent:
February 25, 2014
Assignees:
Oregon Health & Science University, The United States of America as represented by the Department of Veterans Affairs
Inventors:
Deborah A. Lewinsohn, David M. Lewinsohn
Abstract: The passive continuous authentication method uses biometric feedback to perform the authentication processes. Computer software and sensors are provided to acquire, memorize, and authenticate both the user's hard (facial) and soft (clothing) biometric information. A registration phase compels the user to register his/her face image into a registration database. Subsequently, the system permits the user to login the system based on facial recognition of the image presented by an attached webcam of the system. During a computing session the system repetitively authenticates the user's identity by comparing the user's acquired face image (hard biometric) to the registered face image in the database. A clothes color histogram (soft biometric) is also computed. The hard biometric recognition mainly decides the authentication result. Otherwise, clothes color histogram matching takes place to decide the result. When the user leaves the terminal the screen locks up.
Abstract: Disclosed are biodiesel fuels with improved oxidative stability. Disclosed are biodiesel fuels which comprise two or more antioxidants which increase the oxidative stability of the biodiesel fuel.
Type:
Grant
Filed:
February 26, 2009
Date of Patent:
February 25, 2014
Assignee:
Wayne State University
Inventors:
K.Y. Simon Ng, Haiying Tang, Steven O. Salley
Abstract: A solid sorbent for the capture and the transport of carbon dioxide gas is provided having at least one first layer of a positively charged material that is polyethylenimine or poly(allylamine hydrochloride), that captures at least a portion of the gas, and at least one second layer of a negatively charged material that is polystyrenesulfonate or poly(acryclic acid), that transports the gas, wherein the second layer of material is in juxtaposition to, attached to, or crosslinked with the first layer for forming at least one bilayer, and a solid substrate support having a porous surface, wherein one or more of the bilayers is/are deposited on the surface of and/or within the solid substrate. A method of preparing and using the solid sorbent is provided.
Type:
Grant
Filed:
September 12, 2012
Date of Patent:
February 25, 2014
Assignee:
West Virginia University
Inventors:
Bingyun Li, Bingbing Jiang, McMahan L. Gray, Daniel J. Fauth, Henry W. Pennline, George A. Richards
Abstract: A steerable multi-linked device. The device includes a first multi-linked mechanism and a second multi-linked mechanism. At least one of the first and second multi-linked mechanisms is steerable and includes a modular link assembly at an end thereof. The modular link assembly includes a base, and a tip removably connected to the base.
Type:
Grant
Filed:
March 6, 2013
Date of Patent:
February 25, 2014
Assignee:
Carnegie Mellon University
Inventors:
Brett Zubiate, Howard M. Choset, Amir Degani, Michael Schwerin
Abstract: Disclosed is a general methodology to create nano fibers of therapeutic molecules that have a dual role, as both the delivery vehicle and the drug itself. It is shown that with proper molecular design, the integration of enzymatic reaction and self-assembly provides a powerful method to create molecular hydrogels of clinically-used therapeutics without compromising their bioactivities. In addition, the results disclosed herein demonstrate enzyme-instructed self-assembly as a facile strategy for generating the supramolecular hydrogels of molecules that inherently have poor solubility in water. For example, by covalently connecting paclitaxel with a motif that is prone to self-assemble, a hydrogel of paclitaxel can be formed without compromising the activity of the paclitaxel.
Abstract: The present invention provides a method of improving the ductility of a structural member, such as a reinforced concrete beam or column, by providing a region of increased compression yielding in the compression zone of the plastic hinge region or nearby. This can be achieved by using ductile compressive material in the compression zone, or by forming a mechanism provided in the compression zone to provide the ductile compression zone.
Abstract: A nanocrystal described herein comprises a semiconductor material MX, wherein M is a group II or a group III element and X is a group V or a group VI element to provide a II/VI compound or a III/V compound, the nanocrystal having lateral dimensions and a vertical dimension having the shortest axis, wherein surfaces of the nanocrystal normal or substantially normal to the axis of the vertical dimension comprise a layer of M ions passivated by a counter ion chemical species.
Type:
Grant
Filed:
January 9, 2012
Date of Patent:
February 25, 2014
Assignee:
The Board Of Trustees Of The University of Arkansas
Abstract: A method of creating logic chains in a Boolean network of a reconfigurable fabric is provided. The method includes creating a plurality of logic chains in the reconfigurable fabric. The plurality of logic chains include at least one arithmetic logic chain and at least one non-arithmetic logic chain. A method of creating logic chains in a Boolean network of a look-up table based FPGA includes: applying a labeling method by (a) finding a depth increasing node, (b) isolating the depth increasing node, and (c) finding minimum height cuts; mapping to generate a mapping solution using the minimum height cuts; applying a duplication method to implement an exclusivity constraint; and arranging connections in the look-up table based FPGA using the logic chains.
Type:
Grant
Filed:
September 24, 2008
Date of Patent:
February 25, 2014
Assignee:
Iowa State University Research Foundation, Inc.
Abstract: The present invention relates to a positive electrode active material comprising a lithium-containing composite oxide containing nickel with an oxidation state of 2.0 to 2.5 and manganese with an oxidation state of 3.5 to 4.0, the oxidation state determined by the shifts of energy at which absorption maximum is observed in the X-ray absorption near-K-edge structures, and to a non-aqueous electrolyte secondary battery using the same, the positive electrode active material being characterized in having a high capacity, a long storage life and excellent cycle life.
Type:
Grant
Filed:
October 23, 2002
Date of Patent:
February 25, 2014
Assignees:
Panasonic Corporation, Osaka City University
Abstract: With real-world spatial networks the edge travel-times are time-dependent, where the arrival-time to an edge determines the actual travel-time on the edge. To speed up the path computation, exact and approximate techniques for computation of the fastest path in time-dependent spatial networks are presented. An exact fastest path computation technique based on a time-dependent A* search can significantly improve the computation time and storage complexity of existing approaches. Moreover, for applications with which approximate fastest path is acceptable, the approximate fastest path computation technique can improve the computation time by an order of magnitude while maintaining high accuracy (e.g., with only 7% increase in travel-time of the computed path on average). With experiments using real data-sets (including a variety of large spatial networks with real traffic data) the efficacy of the disclosed techniques for online fastest path computation is demonstrated.
Abstract: Methods for inducing, expanding, and/or generating alloantigen-specific regulatory T cells. Alloantigen-specific regulatory T cells can be induced, expanded, and/or generated from naive CD4+CD25? T cells by using CD40-activated B cells. The regulatory T cells can be human T cells. In one embodiment, the alloantigen-specific human regulatory T cells can be CD4highCD25+Foxp3+ regulatory T cells.
Type:
Grant
Filed:
April 30, 2009
Date of Patent:
February 25, 2014
Assignees:
Versitech Limited, The Board of Trustees of the Leland Stanford Junior University
Inventors:
Wenwei Tu, Yu-Lung Lau, David Bram Lewis
Abstract: The present invention provides novel methods and compositions for the diagnosis, prognosis and treatment of breast cancer. The invention also provides methods of identifying anti-breast cancer agents.
Type:
Grant
Filed:
January 31, 2008
Date of Patent:
February 25, 2014
Assignee:
The Ohio State University Research Foundation
Abstract: Carbon nanotube (CNT)-based compositions for activating cellular immune responses are provided. The CNTs function as high surface area scaffolds for the attachment of T cell ligands and/or antigens. The CNT compositions function as artificial antigen-presenting cells (aAPCs) or as modular vaccines. The disclosed CNT aAPCs are efficient at activating T cells and may be used to activate T cells ex vivo or in vivo for adoptive or active immunotherapy.
Type:
Grant
Filed:
March 19, 2009
Date of Patent:
February 25, 2014
Assignee:
Yale University
Inventors:
Tarek M. Fahmy, Lisa D. Pfefferle, Gary L. Haller
Abstract: A patch antenna system comprises a patch antenna having a patch spatially separated from a ground plane; a plurality of pins interposed between the patch and the ground plane selectively connecting the patch to the ground plane; and a control module operably coupled to the plurality of pins and operable to set an operating frequency characteristic of the patch antenna by selectively connecting the patch to the ground plane with one or more of the plurality of pins.
Type:
Grant
Filed:
April 15, 2010
Date of Patent:
February 25, 2014
Assignee:
Board of Trustees Operating Michigan State University
Abstract: ‘Latitude 36 Turf Bermudagrass’ is a clonally propagated F I hybrid from a cross of Cynodon dactylon accession A 12198 (2n=4x=36)×C. transvaalensis OSU selection ‘2747’ (2n=2x=18).
Type:
Grant
Filed:
October 31, 2011
Date of Patent:
February 25, 2014
Assignee:
The Board of Regents for Oklahoma State University
Inventors:
Yanqi Wu, Dennis Loren Martin, Charles M. Taliaferro, Jeffrey A. Anderson, Justin Q. Moss