Abstract: The present invention is directed to a hemostatic textile, comprising: a material comprising a combination of glass fibers and one or more secondary fibers selected from the group consisting of silk fibers; ceramic fibers; raw or regenerated bamboo fibers; cotton fibers; rayon fibers; linen fibers; ramie fibers; jute fibers; sisal fibers; flax fibers; soybean fibers; corn fibers; hemp fibers; lyocel fibers; wool; lactide and/or glycolide polymers; lactide/glycolide copolymers; silicate fibers; polyamide fibers; feldspar fibers; zeolite fibers, zeolite-containing fibers, acetate fibers; and combinations thereof; the hemostatic textile capable of activating hemostatic systems in the body when applied to a wound. Additional cofactors such as thrombin and hemostatic agents such as RL platelets, RL blood cells; fibrin, fibrinogen, and combinations thereof may also be incorporated into the textile. The invention is also directed to methods of producing the textile, and methods of using the textile to stop bleeding.

Abstract: Methods for protecting the brain and other tissues from virus-associated toxicity are provided. Patients are treated with a first immunizing virus prior to administration of a second, therapeutic cytolytic virus. The immunizing virus is preferably administered peripherally, and initiates an adaptive immune response that is sufficient to reduce or prevent the cytovirulence and inflammation caused by the therapeutic virus. The immunizing virus is administered one or more times, preferably at least twice, before administration of the therapeutic virus. The therapeutic virus can be the same virus as the immunizing virus, or a mutant or variant thereof. Preferably the therapeutic virus is an attenuated virus with reduced virulence compared to the immunizing virus.

Abstract: A gaming machine includes a housing, which is playable by a plurality of players, that has a station provided for each individual player; an operation detection unit that detects an operation of a player present at each of the stations performing a bet operation through a bet image displayed on the image display unit; an image capturing unit, provided at the housing, that can capture images of a player present at each of the stations, and a determination unit that determines tampering or an error of a game by comparing image capturing information obtained by the image capturing unit with predetermined information.

Abstract: The present invention provides a method for determining a putative agent that inhibits the SUMO or the SUMO-targeted ubiquitin ligase pathway comprising the steps of contacting mutant MOT1 cells with the putative agent under conditions (1) permitting mutant MOT1 cell growth in the presence of a SUMO or SUMO-targeted ubiquitin ligase pathway inhibitor and (2) not permitting mutant MOT1 cell growth in the absence of a SUMO or SUMO-targeted ubiquitin ligase pathway inhibitor, and measuring cell growth.

Abstract: Methods and systems for predicting statistically probable systematically assigned identifiers are disclosed, as are methods and systems for determining the likelihood that a systematically assigned identifier provided by a purported assignee of the identifier is legitimate. In one example, determining the likelihood of legitimacy includes determining the likelihood that the provided identifier is a valid identifier and determining the likelihood that the provided identifier was assigned to the purported assignee. To accomplish this validation, the present disclosure employs patterns of assignment discernable for systematically assigned identifiers in combination with statistical methods.

Abstract: A biosensor system incorporating CMOS integrated circuits. In one type of biosensor system, the biosensor system includes a silicon substrate. The biosensor system further includes active devices fabricated on the silicon substrate. Additionally, the biosensor system includes a plurality of metal layers stacked on top of the active devices. Furthermore, the biosensor system includes a passivation layer covering a top metal layer, where the passivation layer includes an opening configured to expose the top metal layer, where the opening is used as a sensing electrode. Additionally, the biosensor system includes a plurality of probes attached to the sensing electrode.

Abstract: An optical communication system is provided comprising of a three terminal silicon based light emitting device operating by means of avalanche carrier multiplication and emitting at the below threshold wavelength detection range for Silicon of 850 nm; a low loss optical waveguide operating in the below threshold wavelength detection range for Silicon of 850 nm; and an optical detector, wherein a complete and all-silicon optical communication system is formed being capable of transferring electrical signals in terms of optical intensity variations, such intensities then being propagated through the waveguide and being detected by the optical detector; and being converted back to electrical signals. In a particular mode of operation of the system, wavelength modulation may be obtained. In other applications, transponding action and optical amplification may be obtained.

Abstract: The present invention relates to methods for screening or purifying enteroviruses, a method for mass-producing enteroviruses, and a method for manufacturing an enterovirus vaccine. The method for screening enteroviruses in a sample comprises the following steps: (A) providing a sample and a carrier, wherein monosaccharides such as glucose or galactose are bound to the surface of the carrier, and the monosaccharides have binding affinity to enterovirus; (B) contacting the sample with the carrier; (C) removing components of the sample that do not bind to the carrier; (D) providing a detection unit and contacting the detection unit with the carrier, wherein the detection unit binds to the sample bound on the carrier; and (E) measuring a signal of the detection unit, wherein when the signal of the detection unit is detected, it represents that the enterovirus exists in the sample.

Abstract: The present invention provides an anti-plant virus agent which exhibits preventative and therapeutic effects on plant virus diseases. The anti-plant virus agent of the present invention is characterized by containing at least one compound selected from the group consisting of ascorbic acid derivatives represented by Formula (I) (wherein, R1 to R4 each independently represents a hydrogen atom, —SO3H, —PO3H2, a glycosyl group, or —COR11, wherein R11 represents an unsubstituted or substituted C1-30 alkyl group, or an unsubstituted or substituted C2-30 alkenyl group, with the proviso that R1 to R4 may not all be hydrogen atoms at the same time), and salts thereof.

Abstract: A new configuration for a double-sided rotor, radial flux, air-cored, permanent magnet electric generator (1) is disclosed. The generator (1) includes two radially spaced apart rotor portions (33, 35) defining an air gap between them and each having a plurality of alternating polarity permanent magnets (41) arranged on their inner surfaces, mounted for rotation in the air gap. A modular stator (43) is positioned in the air gap and includes a base (45) having attachment formations (60) spaced apart about its surface and a plurality of individually moulded, polymeric resin stator modules (53). Each stator module (53) has complementary attachment formations (59) for attachment to the base (45) and includes at least one non-overlapping compact wound coil (61) which is embedded within the resin.

Abstract: The present invention provides diagnostic and prognostic assays and kits for determining whether a heart failure patient will respond to a pharmacotherapy. Methods of the invention include determining the expression level of biomarkers that are differentially expressed in a heart failure patient that responds to a pharmacotherapy compared to a heart failure patient that does not respond to a pharmacotherapy.

Abstract: An access catheter system, comprising a needle assembly comprising a needle having an elongate lumen configured to be substantially filled with a fluid. The system further comprises a fluid monitor configured to monitor a physical characteristic of fluid within the lumen, and configured to sense a change in the physical characteristic. An indicator provides a indication of the sensed change in the physical characteristic.

Abstract: Novel resorcinol derivatives and methods of preparation and use are presented. These compounds can stimulate angiogenesis as a biological function triggered by the activation of one cannabinoid receptor distinct from CB1 and CB2. Thus, these compounds are specific ligands for one cannabinoid receptor distinct from CB1 and CB2. The invented compounds, when administered in a therapeutically effective amount to an individual or animal, results in a sufficiently high level of that compound in the individual or animal to cause a physiological response. The physiological response may be useful to treat a number of physiological conditions.

Abstract: The present invention relates to a semiconductor device. The device comprises a semiconductor substrate. A semiconductor drift region is on the semiconductor substrate. The semiconductor drift region comprises a semiconductor region of a first conduction type and a semiconductor region of a second conduction type. The semiconductor region of the first conduction type and the semiconductor region of the second conduction type form a superjunction structure. A high-K dielectric is on the semiconductor substrate. The high-K dielectric is adjacent to the semiconductor region of the second conduction type. An active region is on the semiconductor drift region. A trench gate structure is on the high-K dielectric, the trench gate structure being adjacent to the active region. The semiconductor region of the second conduction type is formed by shallow angle ion implantation, thus its width is narrow and its concentration is high.

Abstract: A sensor with high sensitivity and selectivity for the detection of NO2 uses a simple diode laser operating nominally at 405 nm in the visible region, a high finesse optical cavity and a low noise photon detector. The sensor employs the multimode broad output of the diode laser with the high finesse optical cavity in an essentially off-axis arrangement that can provide large path lengths of the order of a km in a small volume cell. The detected absorption signal corresponds to multiple line integrated absorption spectroscopy (MLIS). Because the sensor uses visible radiation it can employ optics in the visible region that are normally less expensive. Also, the sensor is free from interference from atmospheric water vapor which is often a severe problem for sensors based on mid-infrared quantum cascade lasers operating in the mid-infrared (for example 1650 cm?1) region.

Abstract: The present invention relates to methods for characterization of bacterial skin microbiota to provide diagnostic, therapeutic, and preventive measures for alleviating skin conditions. In certain embodiments, the invention relates to characterization of bacterial skin microbiota associated with psoriasis and related diagnostic, therapeutic, and preventive measures for alleviating psoriasis. These methods will be useful for detecting, diagnosing, and monitoring individuals who have or are at risk of certain skin conditions.

Abstract: Method, system and computer program product for providing real time detection of analyte sensor sensitivity decline is continuous glucose monitoring systems are provided.

Abstract: A method of reducing the potential of pluripotent stem cells to generate teratomas in a subject is provided. The method comprises: (a) transplanting a cell population which comprises the pluriptotent stem cells into the subject; and (b) contacting the pluripotent stem cells with an agent that downregulates an activity and/or expression of a polypeptide selected from the group consisting of AW262311 (aka SerpinB6), COX6A1, ZIC2, SOX2, M14087, OTX2, TUBB2B, IL17RD, TMSL8, CRABP1, ZIC3, CDC20, SBK1, TOP2A, DLG7, PTPRZ1, NUF2, NEFL, SPAG5, LOC146909 and survivin (BIRC5), thereby reducing the potential of the pluripotent stem cells to generate teratomas. Methods of treating tumors and compositions capable of same are also provided.

Abstract: A blood-pumping device comprises a cavity with a U-shaped wall comprising two straight regions connected by an arch-shaped region and a U-shaped tube aligned with the U-shaped wall of the cavity to provide a support for the U-shaped tube, wherein the U-shaped tube comprises two straight regions connected by a semicircular region. The blood-pumping device further comprises an arm rotatable about a center point of the semicircular region, wherein the arm holds two wheels a distance from each other such that upon rotation of the arm the wheels roll along the U-shaped tube while putting pressure on the U-shaped tube, wherein the arch-shaped region of the U-shaped wall of the cavity comprises a recessed portion so that the wheels of the arm impose less pressure on the tube at the recessed portion and upon rotation of the arm generates a pulsating blood flow.

Abstract: The present invention provides a binding molecule which is capable of binding to the human NogoA polypeptide or human NiG with a dissociation constant <1000 nM, a polynucleotide encoding such binding molecule; an expression vector comprising said polynucleotide; an expression system comprising a polynucleotide capable of producing a binding molecule; an isolated host cell which comprises an expression system as defined above; the use of such binding molecule as a pharmaceutical, especially in the treatment of a disease of the peripheral (PNS) and/or central (CNS) nervous system; a pharmaceutical composition comprising said binding molecule; and a method of treatment of a disease of the peripheral (PNS) and/or central (CNS) nervous system.