Abstract: The present invention relates to a biomarker and a composition for diagnosis of preeclampsia. In accordance with one aspect of the present invention, there is provided a biomarker for diagnosis of preeclampsia using an enzyme selected from the group consisting of placental chondroitin 4-O-sulfotransferase 1 (C4ST), chondroitin 6-sulfotransferase (C6S), heparan sulfate 6-O-sulfotransferase 1 (HS6S), and dermatan/chondroitin sulfate 2-sulfotransferase (CS-2OST), or uronic acid-2-sulfate (UA2S).
Type:
Grant
Filed:
February 28, 2011
Date of Patent:
July 3, 2012
Assignee:
Inje University Industry-Academic Cooperation Foundation
Inventors:
Won Sun Park, Na Ri Kim, Mohamad Warda, Jin Han
Abstract: The application provides methods of prognosing and classifying lung cancer patients into poor survival groups or good survival groups and for determining the benefit of adjuvant chemotherapy by way of a multigene signature. The application also includes kits and computer products for use in the methods of the application.
Type:
Grant
Filed:
May 14, 2009
Date of Patent:
July 3, 2012
Assignee:
University Health Network
Inventors:
Ming-Sound Tsao, Frances A. Shepherd, Igor Jurisica, Sandy D. Der, Chang-Qi Zhu, Dan Strumpf, Lesley Seymour, Keyue Ding
Abstract: A data reading method for motion estimation in an embedded system is provided. The embedded system includes an external memory device and a video encoding device, wherein the external memory device stores a first frame, and the video encoding device has an internal memory. First, a second frame is divided into M×N sub frame sets, wherein each of the sub frame sets has O×P sub frames. Then, each of the sub frame sets is selected in a calculation sequence, and the selected sub frame set is stored into the internal memory. Next, a predicted search path of each sub frame in the selected sub frame set is calculated. Thereafter; a predicted reading range is determined, wherein the predicted reading range includes the predicted search paths of the sub frames. Finally, a comparison data is read from the first frame according to the predicted reading range.
Abstract: An image stabilization system includes an optical assembly configured to receive electromagnetic radiation emitted by a target and produce focused image of the target; a focal plane array, the focal plane array being configured to receive the image and integrate at least a portion of the electromagnetic radiation making up the image to produce an electrical representation of the image; sensors configured to provide kinematic data; a control system receiving the kinematic data and estimating jitter-induced motion of the image on the focal plane and outputting a control signal; and actuators configured to receive the control signal and to translate the focal plane along two orthogonal axes and rotate the focal plane about a third orthogonal axis such that jitter-induced motion of the image on the focal plane is reduced.
Type:
Grant
Filed:
December 19, 2008
Date of Patent:
July 3, 2012
Assignee:
Utah State University Research Foundation
Inventors:
Scott A. Anderson, Morgan Davidson, Jason Lee Wooden, R. Camden Robinson, James Peterson
Abstract: Systems and methods of polarization-time coding are disclosed. One method includes encoding information in orthogonal polarizations of light and correlated information in multiple time slots, and transmitting the information using the orthogonal polarizations in the time slots. Another method includes receiving a first input pair which specifies a first polarization state and a second input pair containing which specifies a second polarization state; transforming each input pair according to a matrix specifying a conjugate operation to produce four output pairs. The method further includes transmitting at a first time the first output pair using the first polarization state and the third output pair using the second polarization state. The method further includes transmitting at a second time the second output pair using the first polarization state and the fourth output pair using the second polarization state.
Type:
Grant
Filed:
May 9, 2008
Date of Patent:
July 3, 2012
Assignee:
University of Central Florida Research Foundation, Inc.
Abstract: The present invention includes systems and methods for monitoring endogenous compound concentration in blood by detecting markers, such as odors, upon exhalation by a patient, wherein such markers are the endogenous compound itself or result from the endogenous compound. In the case of olfactory markers, the invention preferably utilizes electronic sensor technology, such as the commercial devices referred to as “artificial” or “electronic” noses or tongues, to non-invasively monitor endogenous compound levels in blood. The invention further includes a reporting system capable of tracking endogenous compound concentrations in blood (remote or proximate locations) and providing the necessary alerts with regard to emergent or harmful conditions in a patient.
Type:
Grant
Filed:
August 29, 2006
Date of Patent:
July 3, 2012
Assignee:
University of Florida Research Foundation, Inc.
Inventors:
Richard J. Melker, David G. Bjoraker, Samsun Lampotang
Abstract: A system (100) including a catheter mounted magneto sensor (114), such as a superconducting quantum interference device (SQUID), and methods using the system are disclosed, where the system and method are designed to detect changes in a magnetic field in a body of interest, such as a patient, to detect changes in a magnetic field in a patient, to identify loci in a target body that accumulate magnetic particles or to identify vulnerable plague in a patient.
Type:
Grant
Filed:
May 11, 2006
Date of Patent:
July 3, 2012
Assignees:
The University of Houston System, Board of Regents, The University of Texas Systems
Inventors:
Audrius Brazdeikis, Jaroslaw Wosik, Paul Cherukuri, Morteza Naghavi
Abstract: A context-based adaptive binary arithmetic coding (CABAC) decoding device and a coding method thereof are provided. The device comprises: a context memory address calculator, calculating an address identifying a memory location in a context model memory for storage of a context model in next cycle; a mixed context memory, in which the context model of the context memory address calculator is stored and from which the context model is read; a two-bin context adaptive binary arithmetic decoder, outputting several parameters for updating the range and offset of the context model, based on the context model of the mixed context memory and deciding several bins; and a binary syntax element comparator, judging whether a current binary sequence corresponds to the value of syntax elements, based on the bins so as to select a correct memory address.
Abstract: A method for making semiconducting carbon nanotubes is provided. A catalyst precursor is disposed on a substrate. The catalyst precursor includes blood. Organic substances contained in the blood are removed and iron ions contained in the blood are oxidized to yield discrete ferric oxide nano-particles on the substrate. The ferric oxide nano-particles are reduced to yield isolated iron nano-particles on the substrate. Carbon nanotubes then grow on the iron nano-particles.
Type:
Grant
Filed:
November 23, 2010
Date of Patent:
July 3, 2012
Assignees:
Tsinghua University, Hon Hai Precision Industry Co., Ltd.
Inventors:
Xue-Shen Wang, Qun-Qing Li, Shou-Shan Fan
Abstract: An electronic device that includes a motion activated amplifier structured to receive a first DC signal having a first DC voltage level and output a second DC signal having a second DC voltage level that is greater than the first DC voltage level. The motion activated amplifier includes a motion activated switch operatively coupled to transformer/rectifier circuitry, wherein the motion activated switch is structured to receive the first DC signal and in response to being moved output an AC signal, and wherein the transformer/rectifier circuitry is structured to receive the AC signal and convert the AC signal into the second DC signal.
Type:
Grant
Filed:
June 10, 2009
Date of Patent:
July 3, 2012
Assignee:
University of Pittsburgh—Of the Commonwealth Systems of Higher Education
Abstract: A modified isolated polypeptide comprising an amino acid sequence encoding a photocatalytic unit of a photosynthetic organism being capable of covalent attachment to a solid surface and having a photocatalytic activity when attached thereto is disclosed.
Abstract: Systems for recording, searching, and outputting display information are provided. In some embodiments, systems for recording display information are provided. The systems include a virtual display that: intercepts display-changes describing changes to be made to a state of a display; sends the display-changes to a client for display; records the display-changes; and a context recorder that records context information describing a state of the display derived from a source independently of the display changes and independently of screen-images. In some embodiments, the systems further include a display system that generates an output screen-image based at least in part on at least one of the display-changes and in response to a search of the context information. In some embodiments, the virtual display further records screen-images; and the display system further generates the output screen-image based at least in part on a recorded-screen-image of the recorded screen-images.
Type:
Grant
Filed:
February 27, 2008
Date of Patent:
July 3, 2012
Assignee:
The Trustees of Columbia University in the City of New York
Inventors:
Ricardo Baratto, Oren Laadan, Dan Phung, Shaya Joseph Potter, Jason Nieh
Abstract: Disclosed is a spotter device and methods for the formation of microassays, biochips, biosensors, and cell cultures. The spotter may be used to deposit highly concentrated spots of protein or other materials on a microarray a slide, wafer, or other substrate. The spotter uses microfluidic conduits and orifices to deposit proteins, other biomolecules, or chemicals on a spot on a substrate. Each orifice is part of a fluid pathways that includes an inlet and outlet conduit. When the spotter contacts a substrate a seal is formed between the orifices and the substrate.
Type:
Grant
Filed:
July 6, 2005
Date of Patent:
July 3, 2012
Assignee:
University of Utah Research Foundation
Inventors:
Bruce Gale, David Chang-Yen, David Myszka
Abstract: The invention provides methods for decreasing or inhibiting herpesviridae (HV) infection or pathogenesis of a cell in vitro, ex vivo or in vivo, a symptom or pathology associated with a herpesviridae (HV) infection or pathogenesis in vitro, ex vivo or in vivo, or an adverse side effect of herpesviridae (HV) infection or pathogenesis in vitro, ex vivo or in vivo. In one embodiment, a method of the invention includes treating a subject with an invention compound (e.g., cationic steroid antimicrobial or CSA).
Type:
Grant
Filed:
September 7, 2010
Date of Patent:
July 3, 2012
Assignees:
Brigham Young University, National Jewish Medical and Research Center
Abstract: The present invention relates to systems and methods for providing a short-acting analgesic agent in the management of pain during labor, wherein the system enables efficient, real-time prediction of contractions for the coordinated administration of analgesia such that the peak effectiveness of the analgesic coincides with the intermittent pain of labor.
Type:
Grant
Filed:
January 7, 2011
Date of Patent:
July 3, 2012
Assignees:
University of Florida Research Foundation, Inc., Convergent Engineering, Inc.
Inventors:
Tammy Y. Euliano, Neil Russell Euliano, II, Jose C. Principe, Dorothee Marossero
Abstract: Bitumen within raw oilsands may be cracked and fully recovered by light hydrocarbon extraction following exposure to modified natural zeolite catalysts under cracking conditions. The recovered bitumen is reduced in viscosity, with lower boiling point distributions. Effective cracking of oilsands bitumen using economical, abundant and readily disposable natural zeolites represents a significant step towards a waterless and environment friendly extraction process.
Type:
Grant
Filed:
April 27, 2009
Date of Patent:
July 3, 2012
Assignees:
The Governors Of The University Of Alberta, Imperial Oil Resource Limited
Inventors:
Steven M. Kuznicki, William C. McCaffrey, Murray R. Gray, James A. Dunn
Abstract: Analyzing a device under test (“DUT”) at higher frequencies. A phase shifter varies the phase of a standing wave on a transmission line coupled to the DUT. The standing wave magnitude is sampled at each of the phase shifts and one or more DUT characteristics are determined as a function of the sampled magnitudes and phase shifts. Further aspects include a related phase shifter comprising a waveguide having a plurality of sub-resonant slots formed therein and having active elements for loading the slots to control the phase shift applied to the signal.
Type:
Grant
Filed:
January 15, 2009
Date of Patent:
July 3, 2012
Assignee:
The Curators of the University of Missouri
Inventors:
Mohamed Ahmed AbouKhousa, Reza Zoughi, Sergiy Kharkivskiy
Abstract: The invention provides a method of preparing a crosslinked polymer, which method comprises polymerising branched polyunsaturated monomers by a metathesis polymerisation reaction, wherein the branched polyunsaturated monomers contain acyclic ethylenically unsaturated groups that are capable of undergoing polymerization by a metathesis reaction such that the metathesis polymerisation produces a crosslinked polymer and substantially no non-volatile ethylenically unsaturated by-products.