Abstract: Methods employing chemiluminescent agents as therapeutically active agents in the treatment of proliferative disorders are disclosed. The chemiluminescent agents are used in the disclosed method without a therapeutically effective amount of a photosensitizer. Novel chemiluminescent agents having the general formula: are also disclosed, wherein X, Y, Z, R3 and R5-R9 are as defined herein.

Abstract: A method of treating a wound in a diabetic patient is provided. The method includes administering a therapeutically effective amount of Chemokine (C-C motif) ligand 2 (CCL2) to a wound site. In another aspect, a method of treating a wound in a diabetic patient is provided. The method includes assaying a level of CCL2 in the diabetic patient relative to a level of CCL2 in a normal subject and administering a therapeutically effective amount of CCL2 to the diabetic patient.

Abstract: It is an object to provide a simplified early diagnosis method for breast cancer, wherein a sample collected from a human subject is analyzed and determination of the presence or absence of breast cancer is made from the proportion of plural types of polyamines including N1-acetylspermidine.

Abstract: A method of making a Coriolis vibratory gyroscope with a three dimensional mushroom resonator element includes defining a cavity in a substrate wafer; bonding a cap wafer onto the substrate over the cavity from which cap wafer the resonator element will be formed; heating the substrate and cap wafer to generate a pressure build-up within the cavity; plastically deforming the cap wafer by the pressure build-up to form the mushroom resonator element having a perimeter around the mushroom resonator element; releasing the three dimensional mushroom resonator element at the perimeter by selectively removing material so that the perimeter of mushroom resonator element is free to vibrate; and disposing a layer of conductive material on the mushroom resonator element to form electrodes thereon for use in driving and sensing vibrations of the mushroom resonator element and its perimeter. A microgyroscope made by such a method is also included within the embodiments.

Abstract: The present invention relates to disubstituted triazoles, their synthesis, and their use as anti-cancer compounds. In particular, compounds of Formula (I) are provided.

Abstract: Provided are compositions and methods employing cells encapsulated within and attached to a hydrogel, e.g., for measuring mechanical strain and/or stress of the cell and for investigating the mechano-chemo-transduction mechanisms at cellular and molecular levels.

Abstract: This disclosure provides methods and compositions related to microbial gene expression. In one aspect, a synthetic polypeptide having a xylose import activity.

Abstract: The present disclosure is directed toward membrane biofilm reactors primarily comprising microorganisms that produce chemical fuel products or precursors thereof. Reactors of the present disclosure can primarily comprise acetogens, a methanotrophs, and/or Methanosarcina acetivorans.

Abstract: A system and a method provide a photovoltaic system which regenerates the output characteristics of the photovoltaic at different ambient condition with high precision under all environmental conditions. The photovoltaic system includes a photovoltaic array, a buck/boost converter, a DC link capacitor to connect the buck/booster converter to a load/inverter, an adaptive network-based fuzzy inference maximum power point tracking controller, a voltage control loop, a proportional integral controller to maintain the output voltage of the photovoltaic array to the reference voltage by adjusting the duty ratio of buck/boost converter.

Abstract: Dimethoxyphenol-based monomers containing polymerizable functional groups such as [meth]acrylate groups are useful for the preparation of polymers, wherein one or more dimethoxyphenyl moieties are part of side chains pendant to the backbones of the polymers. The polymers thereby obtained may have different, improved properties, such as higher glass transition temperatures, thermal stability and solvent resistance, as compared to polymers based on other types of lignin-derived monomers.

Abstract: A system and method to integrate computational fluid dynamics (CFD) and radiotherapy data for accurate simulation of spatio-temporal flow and deformation in real human lung is presented. The method utilizes a mathematical formulation that fuses the CFD predictions of lung displacement with the corresponding radiotherapy data using the theory of Tikhonov regularization.

Abstract: The present invention provides an autonomous mobile-based automated guided vehicle system comprising a system input unit configured to set and input a mobile path between a departure point and an end point of the autonomous mobile-based automated guided vehicle as one or more mobile path blocks in the unit of a block, a system control unit configured to apply a control signal to a corresponding autonomous mobile-based automated guided vehicle based on one or more mobile paths in the unit of a block and a system storage unit configured to store the mobile paths in the unit of a block, which are inputted by a user through the system input unit, and a method for controlling the autonomous mobile-based automated guided vehicle system.

Abstract: An organic device, including semiconducting polymers processed from a solution cast on one or more dielectric layers on a substrate; and electrical contacts to the semiconducting polymers, wherein the substrate and the one or more dielectric layers are flexible and the semiconducting polymers are aligned. The one or more dielectric layers can increase mobility of the semiconducting polymers and/or alignment of the semiconducting polymers with one or more of the nanogrooves in the dielectric layers.

Abstract: The present invention relates to diagnostic tests, methods and kits that are useful to assess a subject's risk of developing a pathologic condition related in part to the presence of HDL oxidation product.

Abstract: A profusion system for a mammalian organ comprising a first and a second pump to propel perfusion fluid through one of a closed fluid circuit system and a selectively closeable fluid circuit system that includes an organ artery and an organ vein, a filter cartridge bank consisting of a plurality of filtration cartridges, and a first and a second fluid reservoir.

Abstract: A four-phase switched reluctance motor torque ripple three-level suppression method. A first set of torque thresholds is set in rotor position interval [0°, ?r/4]. A second set of torque thresholds is set in rotor position interval [?r/4, ?r/2]. Power is supplied to adjacent phase A and phase B for excitation. The power supplied for excitation to phase A leads the power supplied for excitation to phase B by ?r/4. An entire commutation process from phase A to phase B is divided into two intervals. In rotor position interval [0°, ?1], phase A uses the second set of torque thresholds while phase B uses the first set of torque thresholds. Critical position ?1 automatically appears in the commutation process, thus obviating the need for additional calculations. Total torque is controlled between [Te+th2low and Te+th2up].

Abstract: This invention relates to the composition of a chitosan coated paper wherein the chitosan may be derived from a variety of sources. Methods of using chitosan as a surface coating or pulp additive to tune the properties of paper and paperboard products are also described. The chitosan applied is a bio-based and environmentally friendly barrier coating and/or additive material for the manufacture of functional paper and paperboard products, specifically as evaporative cooling media requiring wet strength and structural integrity, wicking, and moisture resistance as an alternative to conventional phenolic-based resins. The solid-state fermentation method to produce chitosan and its derivatives offer renewable bio-based materials towards the manufacture of functional paper products that are eco-friendly but also offer uncompromised performance levels.

Abstract: Methods and compositions for producing 1-butanol are described herein. In some examples, the methods can comprise, contacting a reactant comprising ethanol with a catalyst system, thereby producing a product comprising 1-butanol. The catalyst system can comprise, for example, an iridium catalyst and a nickel, copper, and/or zinc catalyst. The nickel, copper, and zinc catalysts can comprise nickel, copper, and/or zinc and a sterically bulky ligand.

Abstract: One aspect of the invention provides a method of determining metal ion levels in the patents due to corrosion and wear processes of the metallic implant in a human or veterinary patient. One embodiment provides a cost effective and patient driven early diagnostic method which has a potential application in orthopedics and dentistry. In one embodiment, the method includes the use of an electrochemical biosensor to detect metal ions or particles in a sample taken from a patient having a metallic implant.

Abstract: A hydrogel based on a cross-linked ?-polyglutamic acid and ?-polylysine polymer is obtained by cross-linking of ?-polyglutamic acid with ?-polylysine, and it is a polymer having the following constitutional unit, wherein, m is a natural number of 15 to 45, n is a natural number of 3900 to 17000, and x is a natural number of 5 to 40. It also discloses a preparation method of as-described hydrogel and its application in preparation as a medical wound dressing.