Patents Assigned to University
  • System and method for adjusting image parameters based on device tracking
    Patent number: 7894877
    Abstract: A system for automatically adapting image acquisition parameters based on imaging and/or device tracking feedback is provided. An example system includes a subsystem for acquiring images (e.g., MR) of an object and tracking data for a device (e.g. catheter) inserted into the object and controllably moveable within the object. The system also includes an image processor for processing the images and a device tracking logic for computing device parameters (e.g., speed, direction of travel, rate of speed change, position, position relative to a landmark, device orientation). Based on the images and device parameter computations, a parameter control and adjustment logic can automatically update one or more image acquisition parameters that control the image acquisition subsystem.
    Type: Grant
    Filed: May 14, 2003
    Date of Patent: February 22, 2011
    Assignee: Case Western Reserve University
    Inventors: Jonathan S. Lewin, Jeffrey L. Duerk, Daniel Elgort
  • Measurement of renal extraction fraction using contrast enhanced computed tomography
    Patent number: 7894880
    Abstract: Renal extraction fraction (EF) is determined through use of computed tomography (CT) measurements of arterial blood before and after injection of a radiographic contrast agent into the blood and CT measurements of renal vein blood after injection of the radiographic contrast agent.
    Type: Grant
    Filed: October 23, 2003
    Date of Patent: February 22, 2011
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventor: Graham Sommer
  • Straight conveying device for vacuum
    Patent number: 7891932
    Abstract: A working rod with a tip end extending into a vacuum process chamber and moving in the axial direction, two static-pressure gas bearings supporting the rod in the non-contact manner, and an internal moving body of a magnet coupling type driving mechanism driving the rod are housed in a rod housing cylindrical portion leading to the vacuum process chamber, and an exhaust portion by suction is provided at a part of the rod housing cylindrical portion so that the pressure of the rod housing cylindrical portion is lowered than the pressure of the vacuum process chamber by the exhaust from the exhaust portion.
    Type: Grant
    Filed: October 25, 2006
    Date of Patent: February 22, 2011
    Assignees: SMC Corporation, Tohoku University
    Inventors: Soichi Sato, Takashi Abe, Eiko Miyasato, Migaku Takahashi, Masakiyo Tsunoda
  • Solid-solution powder, method to prepare the solid-solution powder, cermet powder including the solid-solution powder, method to prepare the cermet powder, cermet using the cermet powder and method to prepare the cermet
    Patent number: 7892315
    Abstract: Disclosed are a solid-solution powder, a method for preparing the solid-solution powder, a cermet powder including the solid-solution powder, a method for preparing the cermet powder, a cermet using the cermet powder and a method to prepare the cermet. According to the present invention, the problem of low toughness due to high hardness that conventional cermets (especially TiC or Ti(CN) based cermet) have is resolved because a complete solid-solution phase without core/rim structure is provided to the cermets as a microstructure thereof, and in which further increased the hardness as well as the toughness, thereby substantially and considerably increasing general mechanical properties of materials using the cermet, and thus substituting WC—Co hard material and allowing manufacturing of cutting tools with high hardness and toughness.
    Type: Grant
    Filed: January 23, 2009
    Date of Patent: February 22, 2011
    Assignee: Seoul National University Industry Foundation
    Inventor: Shinhoo Kang
  • In vivo production of small interfering RNAs that mediate gene silencing
    Patent number: 7893036
    Abstract: The invention provides engineered RNA precursors that when expressed in a cell are processed by the cell to produce targeted small interfering RNAs (siRNAs) that selectively silence targeted genes (by cleaving specific mRNAs) using the cell's own RNA interference (RNAi) pathway. By introducing nucleic acid molecules that encode these engineered RNA precursors into cells in vivo with appropriate regulatory sequences, expression of the engineered RNA precursors can be selectively controlled both temporally and spatially, i.e., at particular times and/or in particular tissues, organs, or cells.
    Type: Grant
    Filed: March 26, 2008
    Date of Patent: February 22, 2011
    Assignee: University of Massachusetts
    Inventors: Phillip D. Zamore, Juanita McLachlan, Gyoergy Hutvagner, Alla Grishok, Craig C. Mello
  • Apparatus and method for transmitting/receiving a signal in a mobile communication system using a multiple-input multiple-output scheme
    Patent number: 7894544
    Abstract: In a communication system, a signal transceiver generates an upper pre-encoding symbol stream and a lower pre-encoding symbol stream by pre-encoding an upper transmission vector and a lower transmission vector according to a pre-encoding scheme when the upper and lower transmission vectors to be transmitted are input. The signal transceiver generates a space-time mapping matrix by space-time mapping the upper and lower pre-encoding symbol streams according to a space-time mapping scheme based on the number of transmit antennas to be used in the signal transceiver. The signal transceiver generates and transmits a codeword according to whether a null transmission is present in the space-time mapping matrix.
    Type: Grant
    Filed: March 2, 2007
    Date of Patent: February 22, 2011
    Assignees: Samsung Electronics Co., Ltd, Seoul National University Industry Foundation
    Inventors: Ji-Won Bang, Young-Kwan Choi, Dong-Ku Kim
  • Rapid synthesis and size control of chalcopyrite-based semi-conductor nanoparticles using microwave irradiation
    Patent number: 7892519
    Abstract: CuInS2 nanoparticles have been prepared from single source precursors via microwave irradiation. Also, CuInGaS2 alloy nanoparticles have been prepared. Microwave irradiation methods have allowed an increase in the efficiency of preparation of these materials by providing increased uniformity of heating and shorter reaction times. Nanoparticle growth has been controlled in the about 1 to 5 nm size range by variation of thiolated capping ligand concentrations as well as reaction temperatures and times. Investigation of the photophysical properties of the colloidal nanoparticles has been performed using electronic absorption and luminescence emission spectroscopy. Qualitative nanoparticles sizes have been determined from the photoluminescence (PL) data and compared to TEM images.
    Type: Grant
    Filed: December 14, 2007
    Date of Patent: February 22, 2011
    Assignee: Idaho State University
    Inventors: Joshua J. Pak, Joseph S. Gardner, Endrit Shurdha, Rene G. Rodriguez, Lisa D Lau
  • Enhanced bio-assays by using gradient nanotopgraphy
    Patent number: 7892594
    Abstract: A system and method for using gradient nanotopography to increase mammalian cell attachment and cell confinement on surfaces. A surface platform consisting of a thin film of gold possessing a gradient of topography on the surface and self-assembled monolayers of alkanethiols presenting desired functional groups is formed. A gradient in the chemical properties is induced in the terminal groups of the monolayer because of the continuous increase in the surface area and the anisotropy of gold film structure. The gradient nanotopraphy provides simultaneous control of two key properties, the presentation of the terminal functional groups and a continuous increase in the surface density of functional groups on the surface. This control provides for drug screening assays using adherent cell-based experiments.
    Type: Grant
    Filed: November 21, 2006
    Date of Patent: February 22, 2011
    Assignee: Syracuse University
    Inventors: Yan Yeung Luk, Karen A. Simon, Erik A. Burton, Prerli Sejwal, YongBin Han
  • Methods for measuring the metabolism of neurally dervied biomolecules in vivo
    Patent number: 7892845
    Abstract: The present invention relates to methods of diagnosing, monitoring, and assessing treatment effects for neurological and neurodegenerative diseases and disorders, such as Alzheimer's Disease, early in the course of clinical disease or prior to the onset of brain damage and clinical symptoms. Methods of measuring the in vivo metabolism of biomolecules produced in the CNS in a subject are provided.
    Type: Grant
    Filed: April 4, 2006
    Date of Patent: February 22, 2011
    Assignee: Washington University in St. Louis
    Inventors: Randall John Bateman, David Michael Holtzman
  • Humanized antibodies that sequester amyloid beta peptide
    Patent number: 7892545
    Abstract: A method to treat conditions characterized by formation of amyloid plaques both prophylactically and therapeutically is described. The method employs humanized antibodies which sequester soluble A? peptide from human biological fluids or which preferably specifically bind an epitope contained within position 13-28 of the amyloid beta peptide A?.
    Type: Grant
    Filed: February 8, 2008
    Date of Patent: February 22, 2011
    Assignees: Eli Lilly and Company, Washington University
    Inventors: David M Holtzman, Ronald DeMattos, Kelly R. Bales, Steven M. Paul, Naoya Tsurushita, Maximiliano Vasquez
  • Methods and compositions for immunization against chlamydial infection and disease
    Patent number: 7892567
    Abstract: The present invention provides Chlamydia proteins and compositions and methods of use in the treatment/prevention of chlamydial infection in a subject, for eliciting an immune response in a subject and for reducing the likelihood of infertility and reducing the incidence and/or degree of hydrosalpinx due to Chlamydia infection in a subject.
    Type: Grant
    Filed: October 1, 2008
    Date of Patent: February 22, 2011
    Assignee: Board of Regents, The University of Texas System
    Inventors: Bernard P. Arulanandam, Ashlesh K. Murthy, Guangming Zhong
  • Reassembling fragmented files or documents in an order-independent manner that ensures each of the fragments belongs to only one reassembled file
    Patent number: 7895237
    Abstract: Files can be reassembled from fragments by (a) accepting adjacency scores for each pair of fragments from the set of fragments, (b) identifying header fragments from among the fragments of the set of fragments, and (c) for each of the header fragments identified, reconstructing a corresponding one of the two or more files from the fragments of the set of fragments such that the sum of the adjacency scores are optimized, wherein each of the fragments is permitted to belong to only one of the at least two files, and wherein at least two files are reconstructed such that the results are independent of the order in which the files are reconstructed.
    Type: Grant
    Filed: September 19, 2006
    Date of Patent: February 22, 2011
    Assignee: Polytechnic Institute of New York University
    Inventors: Nasir Memon, Anandabrata Pal, Kulesh Shanmugasundaram
  • Systems and methods for displaying three-dimensional images
    Patent number: 7891815
    Abstract: Systems and methods for displaying three-dimensional (3D) images are described. In particular, the systems can include a display block made from a transparent material with optical elements three -dimensionally disposed therein. Each optical element becomes luminous when illuminated by a light ray. The systems can also include a computing device configured to generate two-dimensional (2D) images formatted to create 3D images when projected on the display block, by a video projector coupled to the computing device. The video projector is configured to project the 2D images on the block to create the 3D images by causing a set of the passive optical elements to become luminous. Various other systems and methods are described for displaying 3D images.
    Type: Grant
    Filed: September 29, 2009
    Date of Patent: February 22, 2011
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Shree K Nayar, Vijay Anand Nagarajan
  • Use of N-myristoyltransferase on non-tumor tissue for cancer diagnosis
    Patent number: 7892758
    Abstract: A diagnostic method and kit are disclosed for detection of cancer. Detection of elevated levels of N-myristoyltransferase (NMT) or NMT activity in blood or bone marrow, and specifically in peripheral blood mononuclear cells, can be used as a marker for cancer. The use of this method for detection of adenocarcinoma, such as colorectal cancer, is exemplified.
    Type: Grant
    Filed: September 26, 2006
    Date of Patent: February 22, 2011
    Assignee: University of Saskatchewan
    Inventors: Rajendra Kumar Sharma, Anuraag Shrivastav
  • Converter circuit, analog/digital converter, and method for generating digital signals corresponding to analog signals
    Patent number: 7893859
    Abstract: A charge corresponding to an analog signal Vi is accumulated in first and second capacitors 25, 27, respectively. A digital signal VDIGN having a digital value (D1, D0, for example) corresponding to the analog signal Vi is generated. By connecting the second capacitor 27 between an output 21c and an inversion input 21a of an operational amplifier circuit 21 and supplying a first capacitor end 25a with an analog signal VD/A corresponding to the digital signal VDIGN, a first conversion value VOUT1 is generated in the output 21c of the operational amplifier circuit 21. By connecting the first and third capacitors 25, 33 between the output 21c and inversion input 21a of the operational amplifier circuit 21 and supplying a second capacitor end 27a with the analog signal VD/A, a second conversion value VOUT2 is generated in the output 21c of the operational amplifier circuit 21.
    Type: Grant
    Filed: June 8, 2007
    Date of Patent: February 22, 2011
    Assignee: National University Corporation Shizuoka University
    Inventor: Shoji Kawahito
  • Modulation of an innate immune response by altering TRIAL-R signaling
    Patent number: 7892539
    Abstract: Methods and composition are provided for modulating innate immunity by modulating activation of the TRAIL receptor. Signaling through the TRAIL-R inhibits the responsiveness of cells including dendritic cells, macrophages, and the like. The activity of these cells is increased or decreased by the administration of agents that inhibit or activate TRAIL-R signaling. Innate immunity includes the production of cytokines that act on the immune system.
    Type: Grant
    Filed: March 23, 2005
    Date of Patent: February 22, 2011
    Assignee: The Regents of the University of California
    Inventors: Astar Winoto, Gretchen Elizabeth Diehl, Herman Heng Yue
  • Prognosis and therapy predictive markers and methods of use
    Patent number: 7892740
    Abstract: Disclosed is a set of genes differentially expressed in chemotherapy and radiation resistant tumors useful in predicting response to therapy and assessing risk of local-regional failure, survival and metastasis in cancer patients. Also disclosed are methods for characterizing tumors according to gene expression and kits for use in the methods of the invention.
    Type: Grant
    Filed: January 19, 2007
    Date of Patent: February 22, 2011
    Assignee: The University of Chicago
    Inventors: Ralph Weichselbaum, Bernard Roizman, Andy Minn, Nikolai Khodarev, Edwardine Labay
  • Enhanced sensitivity of a cantilever sensor via specific bindings
    Patent number: 7892759
    Abstract: Detection of miniscule amounts of an analyte is accomplished via multiple bindings of specific materials on a sensor configured to sense mass. The sensor is prepared by immobilizing an antibody to a surface of the sensor, wherein the antibody is known to bind to the analyte. The prepared sensor is exposed to the analyte. The analyte binds to the antibody. The sensor then is exposed to additional antibody, which binds to the analyte. The sensor then can be sequentially exposed to additional antibodies that are known to bind to previously bound antibodies. Each additional binding further increases the effective mass of accumulated material on the sensor. The total effective mass is greater than the mass of the accumulated analyte, thus providing means for detecting extremely minute amounts of analyte. Applications include detection of pathogens and DNA.
    Type: Grant
    Filed: February 15, 2008
    Date of Patent: February 22, 2011
    Assignees: Drexel University, Leversense, LLC
    Inventors: Rajakkannu Mutharasan, David R. Maraldo, Kishan Rijal, Gossett Augustus Campbell, Paul Karl Horan
  • Introduction of structural affinity handles as a tool in selective nucleic acid separations
    Patent number: 7893222
    Abstract: The method is used for separating nucleic acids and other similar constructs. It involves selective introduction, enhancement, or stabilization of affinity handles such as single-strandedness in the undesired (or desired) nucleic acids as compared to the usual structure (e.g., double-strandedness) of the desired (or undesired) nucleic acids. The undesired (or desired) nucleic acids are separated from the desired (or undesired) nucleic acids due to capture by methods including but not limited to immobilized metal affinity chromatography, immobilized single-stranded DNA binding (SSB) protein, and immobilized oligonucleotides.
    Type: Grant
    Filed: December 16, 2003
    Date of Patent: February 22, 2011
    Assignees: University of Houston, Technology Licensing Co. LLC
    Inventors: Richard Coale Willson, III, Luis Antonio Cano
  • Vase
    Patent number: D632996
    Type: Grant
    Filed: November 20, 2009
    Date of Patent: February 22, 2011
    Assignee: University of Iowa Research Foundation
    Inventor: Monica Cruz de Gusmao Correia