Abstract: Devices that include hosts having internal microcapillary networks are disclosed. The microcapillary networks are formed from interconnected passageways. The interconnected passageways may be formed by removing a fugitive material from a cured host material that forms the host. The resultant host material has many applications, including use as a microfluidic device in applications ranging from fluid mixing to structural repair.
Type:
Grant
Filed:
November 9, 2006
Date of Patent:
September 21, 2010
Assignee:
Board of Trustees of University of Illinois
Inventors:
Daniel Therriault, Jennifer A. Lewis, Scott R. White
Abstract: A family of N-substituted 3,4-alkylenedioxypyrrole includes monomers for of formula (I) electropolymerization to conjugated polymers and key intermediates for the preparation of the monomers. The preparation of the //-substituted 3,4-alkylenedioxypyrroles is carried out via a synthetic intermediate, an ester substituted dihydroxypyrrole. The synthetic method to prepare the //-substituted 3,4-alkylenedioxypyrrole intermediates and ultimately the N-substituted 3,4-alkylenedioxypyrrole monomers begins with a reaction to form the ester substituted dihydroxypyrrole.
Type:
Grant
Filed:
October 6, 2006
Date of Patent:
September 21, 2010
Assignee:
University of Florida Research Foundation, Inc.
Inventors:
John R. Reynolds, Ryan M. Walczak, John Sigure Cowart, II
Abstract: The present invention provides a liquid crystal display (“LCD”) panel and manufacturing method thereof. The LCD panel in accordance with the present invention includes a lower substrate including a thin film transistor and a pixel electrode, an upper substrate including a common electrode facing the lower substrate, a liquid crystal layer formed between the upper and lower substrates, and an alignment layer formed of an inorganic substance containing silicon (Si), oxygen (O), and carbon (C) on the upper and lower substrates. The transmittance of light through the LCD panel is high and is practically independent of the deposition temperature of the SiOC alignment layer over a wide range of deposition temperatures. The deposition of the alignment layer can be performed over a wide range of deposition temperatures while maintaining high levels of light transmission.
Type:
Grant
Filed:
December 4, 2007
Date of Patent:
September 21, 2010
Assignees:
Samsung Electronics Co., Ltd., Pusan National University
Inventors:
Soon-Joon Rho, Jang-Sub Kim, Baek-Kyun Jeon, Hee-Keun Lee, Jae-Chang Kim, Tae-Hoon Yoon, Phil-Kook Son, Jeung-Hun Park
Abstract: A field emission lamp generally includes a tube having at least one open end, at least one sealing member respectively arranged in a corresponding open end of the tube, an anode, and a cathode. The anode includes an anode conductive layer formed on an inner surface of the tube, a fluorescent layer formed on the anode conductive layer, and at least one anode electrode electrically connected with the anode conductive layer and extending out of the at least one sealing member. The cathode includes an electron emission element and at least one cathode electrode electrically connected with the electron emission element and extending out of the at least one sealing member. The electron emission element has an electron emission layer. The electron emission layer includes getter powders therein to exhaust unwanted gas in the field emission lamp, thereby ensuring the field emission lamp with a high degree of vacuum during operation thereof. A method for making such field emission lamp is also provided.
Type:
Grant
Filed:
November 21, 2006
Date of Patent:
September 21, 2010
Assignees:
Tsinghua University, Hon Hai Precision Industry Co., Ltd.
Inventors:
Li Qian, Liang Liu, Peng Liu, Jie Tang, Yang Wei, Shou-Shan Fan
Abstract: The invention relates to newly discovered nucleic acid molecules and proteins associated with ovarian cancer. Compositions, kits, and methods for detecting, characterizing, preventing, and treating human ovarian cancers are provided.
Type:
Grant
Filed:
October 7, 2004
Date of Patent:
September 21, 2010
Assignees:
Millennium Pharmaceuticals, Inc., Board of Regents, University of Texas System
Inventors:
Wilson O. Endege, Donna Ford, Manjula Gannavarapu, Karen Glatt, Sebastian Hoersch, Shubhangi Kamatkar, John E. Monahan, Robert Schlegel, Yong Yao Xu, Xumei Zhao
Abstract: Provided herein are systems, methods and compositions for the use of optical coherence tomography for detection of cells and for killing detected cells. A detected cell can be killed or injured by contacting a composition comprised by the cell with energy. Energy can be applied to a particle comprised by the cell.
Type:
Grant
Filed:
April 6, 2007
Date of Patent:
September 21, 2010
Assignee:
Board of Regents, the University of Texas System
Inventors:
Marc D. Feldman, Thomas E. Milner, Jihoon Kim, Junghwan Oh, Pramod Sanghi, Jake Mancuso, Keith P. Johnston, Leo Ma, Stas Emelianov
Abstract: A neutral beam-assisted atomic layer chemical vapor deposition (ALCVD) apparatus is provided for uniformly depositing an oxide layer filling a planarization layer or a trench to increase uniformity and density of the oxide layer using neutral beams generated by a neutral beam generator without a seam or void occurring in an atomic layer deposition (ALD) or ALD-like chemical vapor deposition (CVD) process, thereby solving problems on the void or seam and low density occurring when a high-density planarization layer or a shallow trench having a width of 65 nm or less is formed, and improving a next generation oxide layer isolation process.
Type:
Grant
Filed:
February 14, 2008
Date of Patent:
September 21, 2010
Assignee:
Sungkyunkwan University Foundation for Corporate Collaboration
Inventors:
Geun-young Yeom, Byoung-jae Park, Sung-woo Kim, Jong-tae Lim
Abstract: A piezoelectric device is produced by providing a material having a hydroxyapatite (HA) component. The HA component is textured by, for example uniaxial pressing, to impart one of the limiting symmetries ?, ? mm, or ?2. The textured material may then be poled to enhance the piezoelectric properties.
Abstract: Inhibitors of indoleamine 2,3-dioxygenase (IDO) are provided as are pharmaceutical compositions containing such inhibitors as well as the use of such inhibitors and compositions for the treatment of a condition in a mammalian subject characterized by pathology of the IDO-mediated tryptophan metabolic pathway. Such conditions may involve suppression of T-cell mediated immune response or may directly result from depletion of tryptophan or accumulation of a product of tryptophan degradation. Specific disease conditions include cataracts, age-related yellowing in the eye, neurodegenerative disorders, mood disorders, cancer and various bacterial/viral infections. IDO inhibitors of this invention are substituted naphthalene and anthracene diones. Novel compounds of this invention include the following taurine-substituted naphthaquinone structure.
Type:
Grant
Filed:
July 13, 2005
Date of Patent:
September 21, 2010
Assignee:
The University of British Columbia
Inventors:
Raymond J. Andersen, Alban Pereira, Xin-Hui Huang, Grant Mauk, Eduardo Vottero, Michel Roberge, Aruna Balgi
Abstract: An analytical test for an analyte comprises (a) a base, having a reaction area and a visualization area, (b) a capture species, on the base in the visualization area, comprising nucleic acid, and (c) analysis chemistry reagents, on the base in the reaction area. The analysis chemistry reagents comprise (i) a substrate comprising nucleic acid and a first label, and (ii) a reactor comprising nucleic acid. The analysis chemistry reagents can react with a sample comprising the analyte and water, to produce a visualization species comprising nucleic acid and the first label, and the capture species can bind the visualization species.
Type:
Grant
Filed:
March 15, 2007
Date of Patent:
September 21, 2010
Assignee:
The Board of Trustees of the University of Illinois
Abstract: A high spatial resolution phase-sensitive technique employs a scanning near field ultrasound holography (SNFUH) methodology for imaging elastic as well as viscoelastic variations across a sample surface. SNFUH uses a near-field approach to measure time-resolved variations in ultrasonic oscillations at a sample surface. As such, it overcomes the spatial resolution limitations of conventional phase-resolved acoustic microscopy (i.e. holography) by eliminating the need for far-field acoustic lenses.
Abstract: A carbon dioxide storage system includes a container and a conduit attached to the container for introducing or removing a carbon dioxide-containing composition from the container. A carbon dioxide storage material is positioned within the container. The carbon dioxide-storage material includes a metal-organic framework, which has a sufficient surface area to store at least 10 carbon dioxide molecules per formula unit of the metal-organic framework at a temperature of about 25° C.
Type:
Grant
Filed:
September 26, 2006
Date of Patent:
September 21, 2010
Assignee:
The Regents of the University of Michigan
Abstract: An effective thread number in the thread section which is disposed on the mouth section of the bottle is formed to be 2.2. That is, the thread section is formed such that the thread section 13 should serve effectively in the mouth section such that an interval between a start position and an end position should be 2.0 to 2.5. In the bottle can member 11 which has such a thread section, an outer diameter of the thread section which is formed on the mouth section is 28 to 38 mm. Also, the thickness of the mouth section is 0.25 to 0.4 mm. The thread section which has the effective thread number 2.0 to 2.5 is formed by eight-thread per inch pitch. By doing this, it is possible to put the cap desirably.
Abstract: The invention is based at least in part on the discovery of novel group of genes and/or their encoded gene products that are differentially represented in two substantially enriched CD34+/CD38?/Lin? and CD34+/[CD38/Lin]++ hematopoietic cell populations isolated from normal human bone marrow, cord blood, and peripheral blood stem cell preparations.
Type:
Grant
Filed:
August 9, 2005
Date of Patent:
September 21, 2010
Assignee:
The Johns Hopkins University
Inventors:
Curt I. Civin, Robert W. Georgantas, III
Abstract: A method and architecture for analyzing a computer program by finding similar sections of execution of the computer program. Code of the computer program is run over a plurality of intervals of execution, and during the execution of the program, a statistic is tracked for a component. Using the tracked statistic, behavior of the computer program is identified over each of the plurality of intervals of execution, and at least one identified behavior of at least one interval of execution is compared to the behavior of another interval of execution to find similar sections of behavior.
Type:
Grant
Filed:
September 9, 2003
Date of Patent:
September 21, 2010
Assignee:
The Regents of the University of California
Abstract: The present invention discloses a sigma-delta modulator architecture capable of automatically improving dynamic range and a method for the same. Based on the concept that different dynamic ranges of a sigma-delta modulator can be obtained via adjusting the signal power gain thereof, the present invention provides a novel algorithm to implement an automation program. The present invention finds out several sets of dynamic-range curves to improve the overall dynamic range. Via a high-level sigma-delta modulator architecture, the present invention can calculate the required feedforward coefficients. Further, the present invention install in the sigma-delta modulator architecture with four additional components, including a peak detection unit, a comparator unit, a digital coefficient control unit and a switch unit, to dynamically detect the output of the sigma-delta modulator and dynamically modify the feedforward coefficient of the sigma-delta modulator.
Type:
Grant
Filed:
April 28, 2009
Date of Patent:
September 21, 2010
Assignee:
National Chung Cheng University
Inventors:
Shuenn-Yuh Lee, Rong-Guey Chang, Chih-Yuan Chen, Jia-Hua Hong
Abstract: The present invention relates to a novel class of hydroxamic acid derivatives having at least two aryl containing groups, at least one of which is a quinolinyl, isoquinolinyl or benzyl moiety, linked to the hydroxamic acid group through a methylene chain. The hydroxamic acid compounds can be used to treat cancer, for example, brain cancer. The hydroxamic acid compounds can also inhibit histone deacetylase and are suitable for use in selectively inducing terminal differentiation, and arresting cell growth and/or apoptosis of neoplastic cells, thereby inhibiting proliferation of such cells. Thus, the compounds of the present are useful in treating a patient having a tumor characterized by proliferation of neoplastic cells. The compounds of the invention are also useful in the prevention and treatment of TRX-mediated diseases, such as autoimmune, allergic and inflammatory diseases, and in the prevention and/or treatment of diseases of the central nervous system (CNS), such as neurodegenerative diseases.
Type:
Grant
Filed:
February 22, 2007
Date of Patent:
September 21, 2010
Assignees:
The Trustees of Columbia University in the City of New York, Sloan-Kettering Institute for Cancer Research
Inventors:
Ronald Breslow, Thomas A. Miller, Sandro Belvedere, Paul A. Marks, Victoria M. Richon, Richard A. Rifkind
Abstract: This disclosure provides a system for minimizing the alloreactivity of tissue transplants. The patient is administered with undifferentiated embryonic stem cells or early progenitor cells. This induces a state of inflammatory quiescence or immune unresponsiveness, which in turn enhances engraftment of cells derived from the same stem cell line given for purposes of regenerative medicine.
Type:
Grant
Filed:
September 24, 2004
Date of Patent:
September 21, 2010
Assignees:
Geron Corporation, University of Western Ontario
Inventors:
Mickie Bhatia, Joaquin Madrenas, Iris A. Ferber, Anish Sen Majumdar
Abstract: The present invention relates to lenses that are capable of post-fabrication power modifications. In general, the inventive lenses comprise (i) a first polymer matrix and (ii) a refraction modulating composition that is capable of stimulus-induced polymerization dispersed therein. When at least a portion of the lens is exposed to an appropriate stimulus, the refraction modulating composition forms a second polymer matrix. The amount and location of the second polymer matrix may modify a lens characteristic such as lens power by changing its refractive index and/or by altering its shape. The inventive lenses have a number of applications in the electronics and medical fields as data storage means and as medical lenses, particularly intraocular lenses, respectively.
Type:
Grant
Filed:
May 1, 2007
Date of Patent:
September 21, 2010
Assignees:
California Institute of Technology, The Regents of the University of California
Inventors:
Jagdish M. Jethmalani, Daniel M. Schwartz, Julia A. Kornfield, Robert H. Grubbs, Christian A. Sandstedt
Abstract: A manipulator for use in e.g. a Transmission Electron Microscope (TEM) is described, said manipulator capable of rotating and translating a sample holder (4). The manipulator clasps the round sample holder between two members (3A, 3B), said members mounted on actuators (2A, 2B). Moving the actuators in the same direction results in a translation of the sample holder, while moving the actuators in opposite directions results in a rotation of the sample holder.
Type:
Grant
Filed:
September 26, 2007
Date of Patent:
September 21, 2010
Assignees:
FEI Company, The Board of Trustees of the University of Illinois, The Regents of the University of California
Inventors:
Jeroen van de Water, Johannes van den Oetelaar, Raymond Wagner, Hendrik Nicolaas Slingerland, Jan Willem Bruggers, Adriaan Huibert Dirk Ottevanger, Andreas Schmid, Eric A. Olson, Ivan G. Petrov, Todor I. Donchev, Thomas Duden