Abstract: A fiber is provided, including a cladding material that is disposed along a longitudinal-axis fiber length. A plurality of spherical particles are disposed as a sequence along a longitudinal line parallel to the longitudinal fiber axis in at least a portion of the fiber length. Each spherical particle is of a spherical particle material that is interior to and different than the fiber cladding material. The spacing between adjacent spherical particles in the sequence of particles is greater than the spherical particle diameter. Each spherical particle can be provided as a core-shell particle that includes a spherical core that is surrounded by at least one spherical shell. Each spherical particle can be provided with a plurality of azimuthal sections of at least two distinct materials.

Abstract: A new cultivar of Ribes sanguineum, ‘Oregon Snowflake’, characterized by its compact and densely branched growth habit and highly dissected leaves.

Abstract: A method of improving an error checking and correction performance of a memory includes replacing a defective column including a defective memory cell of the memory cell array with a spare column of a the spare cell array, wherein the memory cell array includes memory cells in a matrix and the spare cell array includes spare memory cells in a matrix to be replaced for defective memory cells; storing check bits of error correction code in at least one memory cell of the defective column; storing defect information regarding a defect of the defective memory cell; determining whether the at least one memory cell storing the check bits is to be used to perform error checking and correction on a memory, based on the defect information; and performing error checking and correction on the memory using a memory cell selected based on a result of determining whether the at least one memory cell storing the check bits is to be used.

Abstract: The invention provides for methods for treating a hair loss disorder in a subject by administering a Janus Kinase/Signal Transducers and Activators of Transcription inhibitor.

Abstract: Methods and compositions for the adsorptive removal of methyl tertiary butyl ether (MTBE) from contaminated water sources and systems. The compositions contain carbon fly ash doped with silver nanoparticles at specific mass ratios. Methods of preparing and characterizing the adsorbents are also provided.

Abstract: The invention relates to novel self-assembling peptide complexes comprising a charged peptide and a polysaccharide, methods of producing them and uses therefor. The novel self-assembling peptide complexes of the present invention have particular utility in the restoration of biomechanical or biochemical function of a variety of biological tissues, for example and without limitation, in degenerated spinal discs, osteoarthritic joints, damaged cartilage, meniscus, ligaments, tendons, dental, ophthalmic and cardiovascular and blood vessel tissues. The invention provides inter alia methods of repairing and or restoring biomechanical or biochemical function of biological tissues and scaffolds for the support of cell growth.

Abstract: The present invention relates to a polymeric substrate being coated with a reflective coating, particularly a chromium-based reflective coating.

Abstract: A monitoring apparatus for deployment on an AUV may include navigation equipment operable independent of guidance and control equipment of the AUV and usable for determining AUV navigation information during deployment of the AUV, radio equipment operable independent of a radio module of the AUV and for providing a communication link to a ground station for communication with testing staff, and a watchdog module comprising processing circuitry configured to monitor at least the AUV navigation information relative to operational guidance to determine whether a constraint defined in the operational guidance is violated.

Abstract: Methods of pre-methylation of foreign DNA to improve genetic transformation in cyanobacterium. Two Type II methyltransferase-encoding genes, i.e., M (sll0729) and C (slr0214), were cloned from the chromosome of Synechocystis sp. PCC 6803 (hereafter Synechocystis 6803) and expressed in E. coli that harbors the integrative plasmid pBS-SPtK or pJU105. After pre-methylation in E. coli, the integrative plasmids were extracted and used for transformation of Synechocystis 6803. The results showed that expression of slr0214 in the integrative-plasmid-harboring E. coli cells before DNA preparation resulted in orders of magnitude higher efficiency in the following integrative transformation of Synechocystis 6803.

Abstract: This disclosure provides systems, methods, and apparatus related to locally doping two-dimensional (2D) materials. In one aspect, an assembly including a substrate, a first insulator disposed on the substrate, a second insulator disposed on the first insulator, and a 2D material disposed on the second insulator is formed. A first voltage is applied between the 2D material and the substrate. With the first voltage applied between the 2D material and the substrate, a second voltage is applied between the 2D material and a probe positioned proximate the 2D material. The second voltage between the 2D material and the probe is removed. The first voltage between the 2D material and the substrate is removed. A portion of the 2D material proximate the probe when the second voltage was applied has a different electron density compared to a remainder of the 2D material.

Abstract: The present invention discloses peptide fragments derived from neuropeptide Y (NPY), which are capable of selective binding to the neural cell adhesion molecule (NCAM) and inducing neuroplastic and neuroprotective effects, and the use of said peptide fragments as neuritogenic agents for treatment of pathological conditions in which neuroprotection and neuroplastic changes are desired, such as brain and retina disorders.

Abstract: Fish bone can be ground into nano-scale particles and then mixed with surimi to form a marinade that can be injected into boneless fish fillets or otherwise added to boneless fish fillets to increase the highly bioavailable dietary calcium content, reduce drip loss and cook loss, improve yield, demonstrate improved texture after frozen storage, and/or provide other benefits. The reintroduction of fish bone back into boneless fish fillets can utilize a conventionally discarded natural resource and reduce waste.

Abstract: The present invention is directed to RNA interference (RNAi) molecules targeted against a Huntington's disease nucleic acid sequence, and methods of using these RNAi molecules to treat Huntington's disease.

Abstract: A circuit and method for generating a signal is disclosed. The circuit includes a set of wide tuning LC tanks, a set of core transistors cross coupled to the set of wide tuning LC tanks, and a combining network coupled to the set of wide tuning LC tanks and the set of core transistors. The combining network further includes a set of inputs connected to the set of wide tuning LC tanks and the set of core transistors, a set of coupling transistors connected to the set of inputs, a set of source inductors connected to the set of coupling transistors, a coupling capacitor connected to the set of source inductors, a load resistor connected to the coupling capacitor. The combining network combines the set of inputs and the signal is delivered to the load resistor as a fourth order harmonic.

Abstract: A device is provided including a first linkage system and a second linkage system. Each linkage system may include an upper support, a lower support, and a cross bar linkage including a first cross bar and a second cross bar. The first cross bar may be configured with a first end pivotally coupled to a first end of the lower support and a second end pivotally coupled to a second end of the upper support. The second cross bar may be configured with a first end pivotally coupled to a second end of the lower support and a second end pivotally coupled to a first end of the upper support. The device may also include a flexible bridging platform coupled to one of the upper support or the lower support of the first linkage system and coupled to the upper support of the second linkage system, and a flexible strut coupled to the lower support of the second linkage system.

Abstract: The present disclosure relates to graphene quantum dot and a method for preparing the graphene quantum dot.

Abstract: The present invention relates to compounds of the formulae herein, their acceptable salts, solvates, hydrates and polymorphs thereof. The compounds of this invention are useful in treatment of disease, particularly leukemia. The invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating disease, disorders, or symptoms thereof in a subject.

Abstract: Certain embodiments are directed to methods of treating respiratory infection by administering an H2S donor.

Abstract: Gait and mobility assessment systems and methods are disclosed. A gait and mobility assessment system comprises a shoe, a plurality of force sensors mounted on the shoe, a plurality of motion sensors mounted on the shoe, and a microprocessor affixed to the shoe. The shoe is adapted to be secured to a foot of a user such that the user may freely ambulate in an unrestricted environment. The force sensors are configured to sense forces exerted by the foot of the user. The motion sensors are configured to sense a motion of the shoe. The microprocessor is coupled to receive data from the plurality of force sensors representing the sensed forces and from the plurality of motion sensors representing the sensed motion. The microprocessor is programmed to (i) store the received data in a memory affixed to the shoe, or (ii) wirelessly transmit the received data to a remote location.

Abstract: The present invention relates to N-heterocyclic sulphonamide compounds, in particular pyrazole sulphonamide compounds, and their use as N-myristoyl transferase inhibitors.