Patents Assigned to University
  • Patent number: 9274036
    Abstract: This invention relates to a method and apparatus for characterizing composite materials, and in particular, to utilizing an artificial neural network for predicting an impact resistance of a composite material. A method for predicting an impact resistance of a composite material in accordance with the present invention includes the steps of designing an artificial neural network including a plurality of neurons, training the artificial neural network to predict the impact resistance by adjusting an output of the plurality of neurons according to sample data and known results of the sample data, inputting data of the composite material into the artificial neural network, and utilizing the artificial neural network to predict the impact resistance of the composite material.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: March 1, 2016
    Assignee: King Fahd University of Petroleum and Minerals
    Inventors: Muhammad Haris Malik, Abdul Fazal Muhammad Arif
  • Patent number: 9274067
    Abstract: Disclosed are systems, devices and methodologies related to calibration of an ion based imaging apparatus such as a proton computed tomography scanner. In some implementations, energy degrader plates having known water-equivalent thickness (WET) values can be introduced to an ion beam to introduce different energy degradation settings. Energy detector responses to individual ions subject to such energy degradation settings can be obtained. Such responses can be normalized and correlated to water-equivalent path lengths (WEPL) of the ions based on the known WET values. Such calibration utilizing degrader plates can be performed relatively quickly and can yield accurate WEPL values that facilitate estimation of, for example, a CT image based on relative stopping power of an object.
    Type: Grant
    Filed: September 22, 2014
    Date of Patent: March 1, 2016
    Assignee: LOMA LINDA UNIVERSITY MEDICAL CENTER
    Inventors: Reinhard W. Schulte, R. Ford Hurley
  • Patent number: 9271679
    Abstract: A method of processing a medical image signal includes estimating first time courses and first spatial patterns for a group of objects from first brain function data for the group, and estimating second time courses and second spatial patterns for a target object from second brain function data obtained from the target object by using the first time courses and the first spatial patterns.
    Type: Grant
    Filed: August 23, 2013
    Date of Patent: March 1, 2016
    Assignees: SAMSUNG ELECTRONICS CO., LTD., Korea University Research and Business Foundation
    Inventors: Hyug-rae Cho, Yong-Hwan Kim, Hei-soog Kim, Jong-Hwan Lee
  • Patent number: 9272914
    Abstract: A uniform Si—NH—Si terminated Si(111) surface is formed by contacting a chlorine-terminated silicon surface with ammonia and a solvent such as an ether.
    Type: Grant
    Filed: November 21, 2011
    Date of Patent: March 1, 2016
    Assignee: UNIVERSITY OF DELAWARE
    Inventors: Fangyuan Tian, Douglass F. Taber, Andrew V. Teplyakov
  • Patent number: 9273158
    Abstract: Environmentally friendly, energy efficient methods for making hydrocarbons, including oxygen containing hydrocarbons, linear or branched polymers, oligomers, waxes, small hydrocarbon molecules, fuels, coatings and starting materials/reactants to be used for making other hydrocarbons. A C1 carbon source, such as coal, natural gas, petroleum or biomass (including non-food biomass), is converted to the desired hydrocarbon. The reaction can be run in water, at room temperature and under atmospheric pressure. In some embodiments, the method comprises combining a) a C1 carbon source; b) water; c) an alkaline agent; and d) an alkyl Lewis acid in an amount effective to initiate or catalyze reaction of the components to form the hydrocarbon.
    Type: Grant
    Filed: May 16, 2012
    Date of Patent: March 1, 2016
    Assignee: The Regents of the University of California
    Inventors: Kenneth J. Shea, Jun Luo
  • Patent number: 9272013
    Abstract: The present invention provides methods for treating a subject that has suffered combined exposure to total body ionizing irradiation and burns by administering a peptide of at least 5 amino acids of a peptide of SEQ ID NO:1 (Asp-Arg-Nle-Tyr-Ile-His-Pro), or a pharmaceutical salt thereof in an amount effective to treat the radiation effects and/or the burn.
    Type: Grant
    Filed: March 28, 2011
    Date of Patent: March 1, 2016
    Assignee: University of Southern California
    Inventors: Kathleen E. Rodgers, Gere S. diZerega
  • Patent number: 9271674
    Abstract: Disclosed herein are systems and methods involving the use of magnetic resonance imaging and optogenetic neural stimulation. Aspects of the disclosure include modifying a target neural cell population in a first region of a brain to express light-responsive molecules. Using a light pulse, the light-responsive molecules in the target neural cell population are stimulated. Multiple regions of the brain are scanned via magnetic resonance imaging. The scans allow for observation of a neural reaction in response to the stimulation in at least one of the multiple regions of the brain.
    Type: Grant
    Filed: June 6, 2014
    Date of Patent: March 1, 2016
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Karl Deisseroth, Jin Hyung Lee
  • Patent number: 9272921
    Abstract: Disclosed are a method of producing fine particulate alkali metal niobate in a liquid phase system, wherein the size and shape of the particulate alkali metal niobate can be controlled; and fine particulate alkali metal niobate having a controlled shape and size. One of specifically disclosed is a method of producing a substantially rectangular cuboid particulate alkali metal niobate represented by MNbO3 (1), wherein M represents one element selected from alkaline metals, including specific four steps. Another one of specifically disclosed is particulate alkali metal niobate represented by the formula (1) having a substantially rectangular cuboid shape, wherein the substantially rectangular cuboid shape has a longest side and a shortest side, the length of the longest side represented by an index Lmax is 0.10 to 25 ?m, and the length of the shortest side represented by an index Lmin is 0.050 to 15 ?m.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: March 1, 2016
    Assignees: Sakai Chemical Industry Co., Ltd., TOHOKU University, Fuji Ceramics Corporation
    Inventors: Atsushi Muramatsu, Kiyoshi Kanie, Atsuki Terabe, Yasuhiro Okamoto, Hideto Mizutani, Satoru Sueda, Hirofumi Takahashi
  • Patent number: 9272051
    Abstract: Provided herein are bitter taste receptor ligands, related agents, combinations, compositions, methods and systems for modulating release of a metabolic hormone in vitro or in vivo from cells of the GI tract of an individual.
    Type: Grant
    Filed: June 30, 2014
    Date of Patent: March 1, 2016
    Assignees: California Institute of Technology, The Regents of the University of California, The United States Government Represented by the Department of Veterans Affairs
    Inventors: William A. Goddard, III, Mark Menna, Stephen Pandol, Ravinder Abrol
  • Patent number: 9274199
    Abstract: NMR probe coils designed to operate at two different frequencies, producing a strong and homogenous magnetic field at both the frequencies. This single coil, placed close to the sample, provides a method to optimize the NMR detection sensitivity of two different channels. In addition, the present invention describes a coil that generates a magnetic field that is parallel to the substrate of the coil as opposed to perpendicular as seen in the prior art. The present invention isolates coils from each other even when placed in close proximity to each other. A method to reduce the presence of electric field within the sample region is also considered. Further, the invention describes a method to adjust the radio-frequency tuning and coupling of the NMR probe coils.
    Type: Grant
    Filed: July 10, 2014
    Date of Patent: March 1, 2016
    Assignees: The Florida State University Research Foundation, Inc, University of Florida Research Foundation, Incorporated
    Inventors: William W. Brey, Arthur S. Edison, Vijaykumar Ramaswamy, Jerris Hooker
  • Patent number: 9273334
    Abstract: The presently disclosed inventive concepts are directed in certain embodiments to a method of producing protoporphyrin IX by (1) cultivating a strain of Shewanella bacteria in a culture medium under conditions suitable for growth thereof, and (2) recovering the protoporphyrin IX from the culture medium. The strain of Shewanella bacteria comprises at least one mutant hemH gene which is incapable of normal expression, thereby causing an accumulation of protoporphyrin IX. In certain embodiments of the method, the strain of Shewanella bacteria is a strain of S. loihica, and more specifically may be S. loihica PV-4. In certain embodiments, the mutant hemH gene of the strain of Shewanella bacteria may be a mutant of shew_2229 and/or of shew_1140.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: March 1, 2016
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Jizhong Zhou, Dongru Qiu, Zhili He, Ming Xie
  • Patent number: 9276063
    Abstract: The invention is drawn to novel nanostructures comprising hollow nanospheres and nanotubes for use as chemical sensors, conduits for fluids, and electronic conductors. The nanostructures can be used in microfluidic devices, for transporting fluids between devices and structures in analytical devices, for conducting electrical currents between devices and structure in analytical devices, and for conducting electrical currents between biological molecules and electronic devices, such as bio-microchips.
    Type: Grant
    Filed: October 29, 2011
    Date of Patent: March 1, 2016
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Jin Z. Zhang, Adam Schwartzberg, Tammy Y. Olson
  • Patent number: 9271853
    Abstract: A vascular stent assembly includes at least a first and a second strut, each including a thickness and a depth. The assembly includes a pair of end radii, with each of the first and second struts extending from one of the pair of end radii. A thickness of at least one of the first and second struts includes a tapering profile extending from one of the end radii to another of the end radii, the tapering profile following a continuously increasing or decreasing function through at least half a length of the at least one strut.
    Type: Grant
    Filed: November 5, 2014
    Date of Patent: March 1, 2016
    Assignee: Brigham Young University
    Inventors: Darrell J. Skousen, Brian D. Jensen, Anton E. Bowden
  • Patent number: 9273318
    Abstract: Dual suppression of the MAP kinase and PI3K/Akt pathways showed synergistic or greatly enhanced anti-melanoma cell effects, compared to suppression of a single pathway, including the inhibition of cell proliferation, transformation and invasion, induction of G0/G1 cell cycle arrest and, importantly, cell apoptosis. Remarkably, suppression of either pathway induces the expression of thyroid iodide-handling genes and dual suppression of the two pathways synergistically and robustly induces expression of these genes, accompanied by uptake of radioiodine in the cells. These genes include sodium/iodide symporter, thyroid-stimulating hormone receptor, thyroglobulin, thyroperoxidase, pendrin gene, thyroid transcription factors (e.g., TTF-1, TTF-2, PAX8) and other thyroid genes.
    Type: Grant
    Filed: January 6, 2014
    Date of Patent: March 1, 2016
    Assignee: The Johns Hopkins University
    Inventor: Michael Mingzhao Xing
  • Patent number: 9275671
    Abstract: An optical information storage medium includes a multilayer film that includes a plurality of extruded alternating active data storage layers and buffer layers, which separate the active data storage layers. The active data storage layers and buffer layers have thicknesses that allow the active data storage layers to be writable by permanent or reversible one- or multiphoton, linear, nonlinear, or threshold optical writing processes to define data voxels within the active data storage layers that are readable by an optical reading device.
    Type: Grant
    Filed: June 11, 2012
    Date of Patent: March 1, 2016
    Assignee: Case Western Reserve University
    Inventors: Kenneth Singer, Chris Ryan, Jie Shan, Joseph Lott, Christophe Weder, Brent Valle, Eric Baer
  • Patent number: 9273127
    Abstract: The invention provides the sequences of two polypeptides comprising the amino acid sequences as shown in SEQ ID NO:1 and SEQ ID NO:2, which can be used for the preparation of monoclonal antibodies against human p28GANK. The invention also provides the monoclonal antibodies against human p28GANK and their use.
    Type: Grant
    Filed: December 9, 2011
    Date of Patent: March 1, 2016
    Assignee: The Second Military Medical University, The People's Liberation Army
    Inventors: Hongyang Wang, Yao Chen, Jing Fu, Dongping Hu, Tao Luo, Liwei Dong
  • Patent number: 9271493
    Abstract: Compositions and methods for the dissolution of a microbial biofilm are provided, where the method comprises contacting a microbiofilm with an effective dose of a curcumin derivative as a biofilm inhibitor. In some embodiments the curcumin derivative is dimethoxycurcumin. In some embodiments the biofilm comprises E. coli, e.g. including uropathogenic E. coli. The biofilm can be present in vitro or in vivo. The biofilm inhibitor may be administered alone, or in combination with bacteriocidal agents.
    Type: Grant
    Filed: June 19, 2013
    Date of Patent: March 1, 2016
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Lynette Cegelski, Ji Youn Lim
  • Patent number: 9273282
    Abstract: The present invention encompasses methods, and kits for the isolation and expansion of T regulatory cells having the CD45RA+ phenotype, including such cells from human umbilical cord blood.
    Type: Grant
    Filed: September 14, 2005
    Date of Patent: March 1, 2016
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Wayne R. Godfrey, Carl June
  • Patent number: 9273252
    Abstract: A method for producing aromatic compounds from fatty acid oils including heating a fatty acid oil to a temperature between about 100° C. to about 800° C. at a pressure between about vacuum conditions and about 200 psia for a time sufficient to crack the oil and produce a cracked fatty acid oil; removing undesired materials, unreacted oil, heavy ends, and light ends from the cracked fatty acid oil; heating the resulting purified cracked fatty acid oil to a temperature between about 100° C. to about 800° C. at a pressure between about vacuum conditions and about 200 psia for a time sufficient to reform alkenes and alkanes in the cracked fatty acid oil into aromatic compounds and produce a reformed fatty acid oil; and extracting components from the reformed fatty acid oil to produce a mixture of chemical products containing between 5% and 90% aromatic compounds by weight.
    Type: Grant
    Filed: April 23, 2012
    Date of Patent: March 1, 2016
    Assignee: University of North Dakota
    Inventors: Wayne Seames, Brian Tande
  • Patent number: 9275456
    Abstract: An embodiment of the current invention includes a non-invasive imaging system, comprising: an imaging scanner suitable to generate an image representing a tissue region of a subject under observation, the tissue region having at least one substructure and the image comprising a plurality of image voxels; a signal processing system in communication with the imaging scanner to receive the imaging signal from the imaging scanner; and a data storage unit in communication with the signal processing system, wherein the data storage unit is configured to store: an atlas comprising spatial information of the at least one substructure in the tissue region, and a database comprising a plurality of pre-stored medical images representing the tissue region, and wherein the signal processing system is adapted to: identify, based on the atlas and for each of the at least one substructure, a corresponding portion of image voxels in the image; provide a computed quantification of the corresponding portion of image voxels for
    Type: Grant
    Filed: October 25, 2011
    Date of Patent: March 1, 2016
    Assignee: The Johns Hopkins University
    Inventors: Susumu Mori, Michael I. Miller, Kenichi Oishi, Andreia V. Faria