Abstract: A method of diagnosing Ankylosing Spondylitis (AS), a spondyloarthropathy, arthritis, psoriasis, type-1 diabetes or a carcinoma comprising typing the ERAP1 haplotype of an individual.

Abstract: A hydrogen sulphide adsorbent is formed from an alkali metal nanotitanate having a portion of the alkali metal cations exchanged with metal cations reactive with hydrogen sulphide, and heat treated. A method for producing the adsorbent includes the steps of mixing an alkali metal nanotitanate in powder form into an aqueous metal cation solution to produce a slurry, which is subsequently dehydrated to produce a powder, which is heat treated. A low temperature method for removing hydrogen sulphide from a gaseous mixture involves exposing the gaseous mixture to the aforementioned adsorbent, at a temperature less than 250° C. The adsorbent maintains a high adsorption capacity over a range of activation temperatures and humidity conditions.

Abstract: Disclosed herein are methods of treating a subject having an altered NRF2/KEAP1 pathway, and compounds and compositions useful in such treatment. Also disclosed herein are methods of evaluating whether to administer a compound that inhibits glutathione production or a glutaminase inhibitor to a subject.

Abstract: The invention relates to a plant based formulation for the prevention and management of obesity and associated complications comprising of an effective amount of hydro-alcoholic extract of Salacia reticulata, Garcinia indica, Dioscorea bulbifera, Terminalia chebula and optionally additives in trace amounts.

Abstract: A particulate decellularized tissue is provided which shows sufficiently effective tissue regeneration and does not show cytotoxicity when used as material for cell culture. In accordance with the method for preparing a particulate decellularized tissue comprising a step of applying a high hydrostatic pressure to animal-derived tissues in a medium, a particulate decellularized tissue is obtained which does not show cytotoxicity but shows the effect of cellular attraction and the effect of induction of cellular differentiation and shows a high effect of tissue regeneration.

Abstract: A sensor that can be used for in-situ structural health monitoring with a triboluminescent material provided on a portion of an optical fiber that may be embedded in materials to be structurally monitored. Damage to the monitored material may result in a triboluminescent emission from the triboluminescent material that can be guided via the optical fiber. Analysis of the triboluminescent emission may provide information on the occurrence, severity and location of damage in a structure.

Abstract: A hollow fiber for use in production of hydrogen gas. The hollow fiber contains a porous support layer having an outer surface and an inner surface, a catalyst layer coated on the outer surface, and a selection layer coated on the inner surface. Also disclosed is a method of preparing such a hollow fiber.

Abstract: A variety of applications, systems, methods and constructs are implemented for use in connection with screening of ion-channel modulators. Consistent with one such system, drug candidates are screened to identify their effects on cell membrane ion channels and pumps. The system includes screening cells having light responsive membrane ion switches, voltage-gated ion switches and fluorescence producing voltage sensors. A chemical delivery device introduces the drug candidates to be screened. An optical delivery device activates the light responsive ion switches. An optical sensor monitors fluorescence produced by the voltage sensors. A processor processes data received from the optical sensor. A memory stores the data received from the optical sensor.

Abstract: A mine elevator is provided having an anti-explosion traction system, an anti-explosion lift car protection system, a flexible guide rail guiding system, a compound lift car, and a counterweight system. The anti-explosion traction system comprises a traction rope tension regulating device, an anti-explosion traction machine, and an anti-explosion control cabinet. The anti-explosion lift car protection system comprises a rope holder, a speed limiter, two hydraulic buffers, a safety clamp, a brake rope, and a brake rope tension buffer device. The flexible guide rail guiding system comprises a steel wire rope guide rail, a guide rail tension device connected to the steel wire rope guide rail and fixed to the an upper platform, a guide rail connection device connected to the steel wire rope guide rail and fixed to a lower platform, and a flexible guide rail guide sleeve fixed to the compound lift car and the counterweight system.

Abstract: A system and method of capturing solar energy, and related method of manufacturing, are disclosed. In at least one embodiment, the system includes a first lens array having a plurality of lenses, and a first waveguide component adjacent to the lens array, where the waveguide component receives light, and where the waveguide component includes an array of prism/mirrored facets arranged along at least one surface of the waveguide component. The system further includes at least one photovoltaic cell positioned so as to receive at least a portion of the light that is directed out of the waveguide. A least some of the light passing into the waveguide component is restricted from leaving the waveguide component upon being reflected by at least one of the prism/mirrored facets, hereby the at least some light restricted from leaving the waveguide component is directed by the waveguide toward the at least one photovoltaic cell.

Abstract: A method for calibrating a laser measuring apparatus having a laser illumination unit and an image capturing unit includes the following steps. A calibration board having at least one slit gap and a plurality of markers is provided. The relative position between the calibration board and the laser illumination unit is adjusted to allow a slit laser beam emitted by the laser illumination unit to pass through the at least one slit. The calibration board is captured by the image capturing unit to generate a calibration board image. The calibration board image is processed so as to obtain a camera coordinate of each of the markers. A plurality of calibration parameters are calculated according to the camera coordinate and an actual coordinate of each of the markers so as to obtain actual coordinates of an object captured in an object image generated by the laser measuring apparatus.

Abstract: Hydroxy acid compound of substituted phenyl ester, preparation method and medical use thereof are provided. The title compound is shown in formula (I), Y?C1-4 straight carbon chain. The compound can release 2,6-diisopropylphenol rapidly under the action of enzymes in vivo, which has sedative, hypnotic and/or anesthetic effect. By protecting the hydroxyl group of 2, 6-diisopropylphenol in compound of formula (I), the first-pass metabolic activity of 2, 6-diisopropylphenol is reduced, so that the synthetic compound can be used for sedation, hypnosis, and/or anesthesia.

Abstract: A method of creating an image mosaic is provided. A plurality of image files is read at a computing device. The plurality of image files contains image data defining a plurality of overlapping images. A dual adjacency mesh for an image mosaic is defined based on an arrangement of the plurality of overlapping images. The dual adjacency mesh is defined as a plurality of nodes and edges that connect a pair of the plurality of nodes. A node is defined for each image of the plurality of overlapping images, and an edge is defined when an overlap exists between a pair of images of the plurality of overlapping images. The image mosaic is presented in a display of the computing device. The image mosaic is created from the plurality of overlapping images based on the defined dual adjacency mesh.

Abstract: A high-finesse Fabry-Perot interferometer (FPI) is introduced into a coherent Brillouin RFL configuration to thereby produce a frequency stabilized random laser.

Abstract: Selective, radically initiated oxidative decarboxylation may produce low viscosity renewable fuels from biologically derived fats and oils. Fatty acids and triglycerides may be decarboxylated using oxidants at a water/oil interface. The oxidants may be produced using photo-Fenton reagents. The reaction advantageously can be carried out at room temperature and pressure and has fewer unwanted byproducts than traditional decarboxylation techniques.

Abstract: The invention provides a method for increasing the solubility of nevirapine, including the steps of rendering nevirapine in a gaseous phase; and rendering the gaseous phase in a relatively more soluble solid particulate form. The invention further provides for a crystalline Form-VI (36) of nevirapine having an X-ray diffraction pattern of (2-theta values in degrees) 9.2953, 11.2023, 12.7019, 12.9796, 13.5273, 15.4670, 17.2597, 19.1038, 19.7267, 21.1303, 22.9381, 25.5589, 26.4913, 27.2150, 27.7283, 29.7134, and 33.8343 degrees two theta. The invention further provides for the preparation of microspherical and/or nanospherical Form-V (34) and crystalline Form-VI (36) of nevirapine as well as novel dosage forms including parenteral-, inhalant-, transdermal- and oral dosage forms.

Abstract: An omnibus process of pulping and bleaching lignocellulosic materials in which a charge of a lignocellulosic material is biopulped and/or water extracted prior to pulping and bleaching. The lignocellulosic material may be mechanically pulped and bleached in the presence of an enzyme that breaks lignin-carbohydrate complexes. The aqueous extract in embodiments including a water extract step is separated into acetic acid and hemicellulose sugar aqueous solutions.

Abstract: The present invention provides an optically induced cell lysis biochip, which comprises: an upper substrate made of a transparent, electrically conductive material; a lower substrate made of a transparent, electrically conductive material; a photoconductive layer formed under the lower surface of the upper substrate or on the upper surface of the lower substrate; and a chamber formed between the upper substrate and the lower substrate. When there is an electric potential difference between the upper and lower substrates, a light spot illuminated on the photoconductive layer can cause the impedance of the illuminated area to decrease, thereby causing the electric current to center on the illuminated area of the photoconductive layer. Further, the electric current flowing through the illuminated area can induce the cell lysis process of a target cell.

Abstract: Nucleic acid molecules and compositions comprising: a nucleic acid sequence that encodes IL-12 p35 subunit or a functional fragment thereof and/or a nucleic acid sequence that encodes IL-12 p40 subunit or a functional fragment thereof, are disclosed. The nucleic acid molecules and compositions further comprising a nucleic acid sequence that encodes an immunogen are also disclosed. Method of modulating immune response and methods of inducing an immune response against an immunogen are disclosed. Therapeutic and prophylactic vaccination methods are also disclosed.

Abstract: The present disclosure relates to a porous carbon particle of which a pore size can be controlled by using a copolymer that allows selective cross-linking of a polymer particle and selective carbonization of a polymer particle, and a producing method of the porous carbon particle and a photo electrode including a porous layer containing the porous carbon particle and a dye-sensitized solar cell including the photo electrode.