Patents Assigned to University
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Patent number: 7577418Abstract: A sub-harmonic mixer and a down converter with the sub-harmonic mixer are provided. The sub-harmonic mixer includes a differential amplifying unit, a current buffer unit, and a switching unit. The differential amplifying unit is used to amplify a radio frequency (RF) signal and employs a first resonance circuit to force a leakage signal to flow to a first voltage. The current buffer unit is used to amplify the gain of an output signal of the differential amplifying unit and employs a second resonance circuit to force the leakage signal to flow to a second voltage. Finally, the switching unit switches an output signal of the current buffer unit into a base band signal.Type: GrantFiled: July 18, 2006Date of Patent: August 18, 2009Assignees: United Microelectronics Corp., National Taiwan UniversityInventors: Jen-Chung Chang, Chia-Jung Hsu, Shey-Shi Lu, Hsiao-Chin Chen, Tzu-Chao Lin
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Patent number: 7576580Abstract: Systems and methods for active clock deskew are provided. The disclosed systems/methods advantageously achieve desirable clock deskew at reduced power levels by employing a resistance-based distributed clock deskew technique. The disclosed technique has broad commercial/industrial applicability, e.g., in VLSI/ULSI chips, such as microprocessors, digital signal processing systems (DSPs), integrated circuits, application-specific integrated circuits (ASICs), micro-controllers, embedded systems, memory chips and the like.Type: GrantFiled: April 26, 2006Date of Patent: August 18, 2009Assignee: University of ConnecticutInventor: Lei Wang
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Patent number: 7576627Abstract: This invention provides a novel electronically tunable active duplexer for wireless transceiver applications. It relates to an active duplexer with full-duplex operation, permitting simultaneous transmission and reception of signals at same or different frequencies. It incorporates varactors, instead of fixed or mechanically adjustable capacitors, in phase shifting networks enabling one to electronically tune, with ease and precision, the frequency at which isolation is desired, over a band in both transmit and receive modes of operations. It can be implemented as a Monolithic Microwave Integrated Circuit (MMIC).Type: GrantFiled: April 23, 2007Date of Patent: August 18, 2009Assignee: Bradley UniversityInventors: Prasad Narasimha Shastry, Balamurugan Sundaram
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Patent number: 7576213Abstract: A hitherto unknown class of chemical compounds, 2H-furo[2,3-c]pyran-2-ones including derivatives and analogues thereof are disclosed herein. Methods for making compounds within said class are disclosed herein and includes, without limitation, at least the intermediates employed in the generation of said compounds. The invention also relates to the use of vinylogous 4H-pyrones, including but not limited to the hitherto unknown 2H-furo[2,3-c]pyran-2-ones. Disclosed herein are methods comprising the step of exposing biological plant material to at least a compound of the invention to promoting bioactivity within said material. In another aspect in methods for promoting growth of plant material in, for example, smoke-responsive plant species by exposing said material to a compound of the invention are disclosed herein. More specifically, methods comprising the use of these compounds for promoting seed germination of a plant, for example, a smoke-responsive plant, are disclosed herein.Type: GrantFiled: June 19, 2006Date of Patent: August 18, 2009Assignee: The University of Western AustraliaInventors: Gavin Ray Flematti, Emilio Luciano Ghisalberti, Kingsly Wayne Dixon, Robert Donald Trengove
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Patent number: 7575554Abstract: In medical situation, a self breathing holding method using no breathing monitoring device shows inferior accuracy in holding breathing by a patient with poor understanding of the self breathing holding method. In view of the above, development of a readily understandable breathing holding method and breathing monitoring device with high accuracy has been desired. A breathing monitoring device having a multi-point detector comprises a housing mounted to a treatment couch for a patient to lie thereon, so as to cover the patient's body, such as a chest, an abdomen, or the like; a displacement amount determination unit mounted to the housing, for determining displacement amounts of at least two points on the patient's chest and abdomen; and a respiration level determination unit for determining a combined displacement amount which is a combination of the displacement amounts determined of the patient's chest and abdomen due to respiration.Type: GrantFiled: September 21, 2007Date of Patent: August 18, 2009Assignee: University of YamanashiInventor: Hiroshi Onishi
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Patent number: 7575861Abstract: The invention provides improved assays for detection of pregnancy. In the assays, pregnancy associated glycoproteins are analyzed in conjunction with progesterone analysis. The techniques of the invention overcome limitations in the prior art by reducing the rate of false positive results. The assays provided by the invention can be implemented to increase the efficiency of commercial animal breeding programs.Type: GrantFiled: November 20, 2002Date of Patent: August 18, 2009Assignees: Monsanto Technology LLC, The Curators of the University of MissouriInventors: Matthew C. Lucy, Nagappan Mathialagan
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Patent number: 7576325Abstract: There is provided an electron microscopic method capable of realizing a high resolution based on the principle of the phase retrieval method. An electron microscope (10) using the method is a device dedicated to the phase retrieval method in which hardware (incident system (100), a sample system (200), a detection system (300), a computer system (400)) and software (constriction condition, optimization method) are formed into a unitary block. The intensity distribution and the phase distribution of the support slit (210) are given as a real space constriction condition. The detection system (300) includes a course system having an objective lens (310) and a course detector (320) and a fine system has a fine detector (330). The course image is acquired by electrically turning on the objective lens. After acquiring the diffraction pattern by electrically turning off the objective lens, the fine image is reconfigured by the phase retrieval method using the obtained course image and diffraction pattern.Type: GrantFiled: May 20, 2005Date of Patent: August 18, 2009Assignee: National University Corporation Hokkaido UniversityInventor: Kazutoshi Gohara
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Patent number: 7576933Abstract: This invention provides a system and a method of the optical delay line, wherein the system comprises a source and an array of mirrors, wherein the array of mirrors comprises a first reflective mirror, a second reflective mirror, a third reflective mirror, and a fourth reflective mirror. Beams from the source could be delayed because the beams are multi-reflected by the reflective mirrors.Type: GrantFiled: June 5, 2007Date of Patent: August 18, 2009Assignee: Chung Yuan Christian UniversityInventors: I-Jen Hsu, Chia-Yun Kao, Cheng-Chung Lai, Chao-Ming Chang, Ti-Kuang Hou
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Patent number: 7577266Abstract: System (10) is disclosed including an acoustic sensor array (20) coupled to processor (42). System (10) processes inputs from array (20) to extract a desired acoustic signal through the suppression of interfering signals. The extraction/suppression is performed by modifying the array (20) inputs in the frequency domain with weights selected to minimize variance of the resulting output signal while maintaining unity gain of signals received in the direction of the desired acoustic signal. System (10) may be utilized in hearing, cochlear implants, speech recognition, voice input devices, surveillance devices, hands-free telephony devices, remote telepresence or teleconferencing, wireless acoustic sensor arrays, and other applications.Type: GrantFiled: July 11, 2006Date of Patent: August 18, 2009Assignee: The Board of Trustees of the University of IllinoisInventors: Albert S. Feng, Michael E. Lockwood, Douglas L. Jones, Carolyn J. Bilger, legal representative, Charissa R. Lansing, William D. O'Brien, Bruce C. Wheeler, Robert C. Bilger
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Patent number: 7576839Abstract: The present invention relates to a method and apparatus used to calculate at least one velocity component for a target within the region. The invention employs an energy source which is activated using an activation system in a cyclic pattern with a selected source frequency. A receiver is also employed in conjunction with a shielding system where this shielding system is configured to block the sensing of reflected energy from the target in a cyclic pattern with a selected receiver frequency. The invention operates through measuring a frequency change in the source frequency of the energy source signal when received by the receiver and determines a velocity component for a target based on a measured frequency change for a known direction of travel. The invention may also be extended to provide a two or three dimensional velocity vector through the addition of further energy sources.Type: GrantFiled: September 13, 2005Date of Patent: August 18, 2009Assignee: The University of WaikatoInventors: Dale Anthony Carnegie, Michael John Cree, Adrian Andrew Dorrington
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Patent number: 7575908Abstract: A method and kit for immobilization of a glycoprotein. The method may include activating an affinity support. The affinity support may be activated by reacting the affinity support with a compound that is reactive with one or more functional groups included within the glycoprotein. The method may also include oxidizing the glycoprotein in which oxidation conditions are selected to yield an oxidized glycoprotein that is biologically active and contains a sufficient number of reactive aldehyde groups for coupling to a support. For example, the oxidized glycoprotein may include five reactive aldehyde groups. In addition, the method may include reacting the oxidized-glycoprotein with the activated affinity support to immobilize the glycoprotein.Type: GrantFiled: April 11, 2006Date of Patent: August 18, 2009Assignee: Board of Regents of the University of NebraskaInventors: David S. Hage, Hai Xuan
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Patent number: 7576181Abstract: The present invention provides a method of administering porcine B-domainless factor VIII (OBI-1) to a patient having factor VIII deficiency to provide more rapid and effective protection against bleeding episodes, compared to formerly available methods, or to provide more effective protection to such patients during non-bleeding periods. This invention is based on the discovery that the recombinant B-domainless porcine fVIII, termed OBI-1, has greater bioavailability compared to the natural porcine fVIII partially purified from porcine plasma, termed HYATE:C. Therefore, the inventive method employs lower unit doses of OBI-1, including, alternatively, omission of antibody-neutralizing dosage, or has longer intervals between the administration, compared to HYATE:C, to provide equivalent protection in patients having fVIII deficiency.Type: GrantFiled: October 12, 2006Date of Patent: August 18, 2009Assignees: IPSEN Biopharm Limited, Emory UniversityInventors: John S. Lollar, Garrett E. Bergman
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Patent number: 7576342Abstract: The invention is intended to increase the number of patients treatable using one wheel having a thickness varied in the rotating direction to change energy of an ion beam passing the wheel. Ion beam delivery equipment for irradiating an ion beam to a patient for treatment comprises a beam generator for producing and accelerating the ion beam, an beam delivery nozzle including a range modulation wheel which has a predetermined thickness distribution in the rotating direction and is rotated on a travel passage of the ion beam generated from the beam generator to control a range of the ion beam, and an irradiation controller for controlling the beam producing and accelerating operation of the beam generator in accordance with the phase of rotation of the range modulation wheel.Type: GrantFiled: June 6, 2007Date of Patent: August 18, 2009Assignees: Hitachi, Ltd., Board of Regents, University of Texas SystemInventors: Kazuo Hiramoto, Hiroshi Akiyama, Masaki Yanagisawa, Hisataka Fujimaki, Alfred P. Smith, Wayne Newhauser
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Patent number: 7575763Abstract: Membrane proteins are difficult to express in recombinant form, purify, and characterize, at least in part due to their hydrophobic or partially hydrophobic properties. Membrane scaffold proteins (MSP) assemble with target membrane or other hydrophobic or partially hydrophobic proteins or membrane fragments to form soluble nanoscale particles which preserve their native structure and function; they are improved over liposomes and detergent micelles. In the presence of phospholipid, MSPs form nanoscopic phospholipid bilayer disks, with the MSP stabilizing the particle at the perimeter of the bilayer domain. The particle bilayer structure allows manipulation of incorporated proteins in solution or on solid supports, including for use with such surface-sensitive techniques as scanning probe microscopy or surface plasmon resonance. The nanoscale particles facilitate pharmaceutical and biological research, structure/function correlation, structure determination, bioseparation, and drug discovery.Type: GrantFiled: May 23, 2006Date of Patent: August 18, 2009Assignee: The Board of Trustees of the University of IllinoisInventors: Stephen G. Sligar, Timothy H. Bayburt
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Patent number: 7575873Abstract: The invention provides a novel human Mab Fab, cloned by phage display, and its use in diagnostic and therapeutic methods. In particular the invention provides a method for analyzing the OxLDL components of atherosclerotic plaques in vivo and a means to determine their relative pathology. As the method is based on a human Fab rather than a mouse Mab, the progress or regression of the disease may be monitored over time. The antibody may also be used for the analysis of surgical or serum samples ex vivo for the presence of OxLDL. The antibody may also be used to target therapeutic agents to the site of atherosclerotic plaques or may have use as a therapeutic agent itself.Type: GrantFiled: November 12, 2003Date of Patent: August 18, 2009Assignee: The Regents of the University of CaliforniaInventors: Joseph L. Witztum, Sotirios Tsimikas, Wulf Palinski
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Patent number: 7575926Abstract: A method for identifying compounds capable of targeting suppressed cancer cells, the method including the steps of comparing the response to a test compound of cancer cells grown on a suppressing cell support matrix which causes suppression of a malignant phenotype in a growing cancer cell and on a non-suppressing cell support matrix.Type: GrantFiled: December 19, 2006Date of Patent: August 18, 2009Assignee: The Board of Regents of the University of OklahomaInventors: Robert E. Hurst, Michael A. Ihnat, Kimberly D. Kyker
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Patent number: 7576184Abstract: This invention relates to allergenic proteins of natural rubber latex in substantially purified form, their production and their use, together with monoclonal antibodies developed against those allergenic proteins, in assays for the qualitative and quantitative determination of the levels of the allergenic proteins in natural rubber latex or in products made from latex. Assays for identifying and/or quantitating antibodies in blood or blood products that mediate the occurrence of an allergic reaction induced by natural rubber latex are also provided, together with in vivo and in vitro diagnostic tests for detecting hypersensitivity to natural rubber latex and which involve use of the aforesaid allergenic proteins. The invention also provides for the use of the aforesaid allergens as de-sensitising agents in the treatment of latex protein allergy. There is still further provided a method for removing allergenic proteins from latex products.Type: GrantFiled: April 8, 2004Date of Patent: August 18, 2009Assignees: The Board of the Rubber Research Institute of Malaysia, Universiti Sains MalaysiaInventors: Mary Jane Cardosa, Hamid Sharifah, Shirley Samuel-Verghese, Elumalai Sunderasan, Hoong Yeet Yeang, Hamzah Samsidar
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Patent number: 7575858Abstract: A method of visualizing proteins bound to a protein-binding membrane is provided herein, comprising reacting proteins bound to protein-binding membranes with a compound of formula (I) wherein Ra, R1, R2, R3, R4, M, n, and m are as defined herein.Type: GrantFiled: September 9, 2003Date of Patent: August 18, 2009Assignee: Temple University—Of The Commonwealth System of Higher EducationInventors: Christopher R. Yonan, Frank N. Chang
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Patent number: 7576058Abstract: The present invention relates to the delivery of biologically active molecules, such as peptides, nucleic acids and therapeutic agents, into the interior of cells by administering to the cells a complex comprising the molecule linked to an importation competent signal peptide. Such delivery can be utilized for purposes such as peptide therapy, gene transfer, and antisense therapy.Type: GrantFiled: March 1, 2000Date of Patent: August 18, 2009Assignee: Vanderbilt UniversityInventors: Yao-Zhong Lin, Jack J. Hawiger
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Patent number: 7576323Abstract: A point-of-care mass spectrometer system has a sampling system, an ionization component structured to receive a sample for analysis from the sampling system, a mass analyzer structured to receive a source of ions for analysis from the ionization component, and a detector structured to detect ions from the mass analyzer and to generate an output signal. The sampling system selects a subset of peptides from a sample by immunopurification of multiple histocompatability complexes and concentrates the subset of peptides to provide the sample to the ionization component.Type: GrantFiled: September 27, 2005Date of Patent: August 18, 2009Assignee: Johns Hopkins UniversityInventor: Robert James Cotter