Abstract: Cyclic alkyl, particularly cyclohexyl, substituted glycolides and polylactides are described. The polylactides have a high glass transition temperature and improved clarity.

Abstract: Translating named entities from a source language to a target language. In general, in one implementation, the technique includes: generating potential translations of a named entity from a source language to a target language using a pronunciation-based and spelling-based transliteration model, searching a monolingual resource in the target language for information relating to usage frequency, and providing output including at least one of the potential translations based on the usage frequency information.

Abstract: The present invention relates to compositions and methods for the use of SENP1 as a marker for cancer diagnosis, specifically prostate cancer. Still further, it relates to the use of inhibitors of SENP1 to inhibit cell proliferation of a neoplasm or tumor cell and to treat a hyperproliferative disease.

Abstract: A system and method used to assess animal behavior includes a module having sensors that collects a variety of physical and biological data from a test subject. Interpretation of the data is provided to assess the test subjects behavior, neurology, biochemistry and physiology. The module is useful in observing the effects of a drug on the test animal and providing information on the drug's signature. Another advantage is the module's portability that allows it to be used in standard laboratory cages. This portability allows the animal to be tested in its own habitat, that can reduce any erroneous data due to stressing the animal when removed to a test cage. Additionally, the module's design allows for parallel data collection and interpretation from several laboratory animals undergoing different experiments. Multi-dimensional modeling of the test subject based the system's interpretation of the data allows pattern recognition of the drug signature, and predictive drug analysis.

Abstract: A surface acoustic wave (SAW) device which is made of cBN/diamond composite structures and the fabrication method are disclosed. In the SAW device based on cubic boron nitride and diamond composite structures, the diamond hard layer includes randomly-oriented polycrystalline diamond (poly-D), oriented (heteroepitaxial) diamond, single-crystal diamond wafers and nanocrystalline diamond (nano-D) films. The cBN film with a sound velocity close to that of diamond serves as the piezoelectric layer, which was directly deposited on diamond hard layer without any soft sp2-BN incubation layer by ion assisted physical vapor deposition (PVD) and plasma-enhanced (or ion assisted) chemical vapor deposition (PECVD). Due to the high sound velocity and the low velocity dispersion between the cBN and diamond layered materials, the present SAW device based on cubic boron nitride and diamond composite structures can improve the device performance and operate at ultra-high frequency range.

Abstract: Conductimetric assay devices that have both low end and high end sensitivity are described. The geometric shape and/or arrangement of the capture zones make it possible for the assay devices to have both low end and high end sensitivity. Also described is a conductimetric assay device having a pre-capture zone to capture unbound analyte. The assay device overcomes the problem of flooding by the analyte.

Abstract: A field emission electron source (10) includes a conductive base (12), a carbon nanotube (14), and a modifying layer (16). The conductive base includes a top (122). One end (142) of the carbon nanotube is electrically connected with the top of the conductive base. The other end (144) of the carbon nanotube extends outwardly away from the top of the conductive base. The modifying layer (16) is uniformly distributed and coated onto at least the surface of the other end of the carbon nanotube. The work function of the modifying layer is lower than that of the carbon nanotube.

Abstract: Disclosed herein are novel methods for screening for compounds useful in treating or preventing tuberculosis. In exemplary embodiments, screening methods are based on the implementation or manipulation of triacylglycerol synthase like polypeptides or polynucleotides encoding the same. The methods are useful in identifying agents active against TB infection.

Abstract: The present invention discloses a method for inspecting an object using multi-energy radiations and an apparatus thereof. The method comprises the steps of: causing multi-energy radiations to interact with an object under inspection; detecting and recording detection values after an interaction between the multi-energy radiations and the object under inspection; substituting a portion of the detection values into a predetermined calibration function to obtain information comprising primary material attribute; and determining further material attributes of the object by applying a set of functions suitable for a energy band corresponding to the information. The present invention is applicable to the large container cargo inspection without opening containers at customs, ports and airports.

Abstract: A method of enhancing the production of gametes in a transgenic non-human animal is carried out by: (a) providing a transgenic non-human animal comprising cells that contain: (i) a response element; (ii) a nucleic acid encoding FSH? operatively associated with the response element; (iii) an FSH? promoter; (iv) an FSH? locus control region operatively associated with the FSH? promoter; and (v) a nucleic acid encoding a ligand-controllable receptor operatively associated with the FSH? promoter, wherein the receptor binds to the response element in the presence of the ligand when expressed in a host cell; and (b) administering the ligand to the animal in an amount effective to (i) stimulate the production of FSH? in the animal above that found in a corresponding untransformed type animal; and (ii) stimulate the production of gametes in the animal to a level greater than that found in the corresponding untransformed animal.

Abstract: The present invention is generally directed to new liquid-liquid extraction methods for the length-based separation of carbon nanotubes (CNTs) and other 1-dimensional nanostructures.

Abstract: Systems and methods for creating and using a conditioning signal are provided. In some embodiments, systems for creating a conditioning signal providing information regarding an input signal are provided, wherein the systems comprise: a signal conditioning developer that receives the input signal and produces the conditioning signal; a delay device that receives the input signal and produces a delayed input signal, wherein the delayed input signal is delayed to simultaneously transmit with the conditioning signal and form a vector signal with the delayed input signal and the conditioning signal; and a receiving circuit coupled to the signal conditioning developer and the delay device that receives the vector signal and dynamically adjusts according to the conditioning signal.

Abstract: This invention provides analogs of hemiasterlin, methods of synthesis of the analogs and use of the analogs as cytotoxic and anti-mitotic agents.

Abstract: A method for photo-detecting and an apparatus for the same are provided. The apparatus for photo-detecting includes a first P-N diode and a second P-N diode. The first P-N diode, has a first P-N junction which has a first thickness, by which a first electrical signal is generated when irradiated by light, and the second P-N diode has a second P-N junction which has a second thickness, by which a second electrical signal is generated when irradiated by light. The second thickness is larger than the first thickness and an operation of the first electrical signal and the second electrical signal is proceeded for obtaining a third electrical signal.

Abstract: A method and a micro power generator for generating electrical power from low frequency, vibrational energy includes a frequency up-conversion process. The generator is preferably an electromagnetic, vibration-to-electrical power generator which can efficiently scavenge energy from low frequency external vibrations. The generator up-converts low frequency environmental vibrations to a much higher frequency through a mechanical frequency up-converter, and hence provides efficient energy conversion even at low frequencies. This mechanical frequency up-conversion process can be realized in a number of ways. A magnetic method is described as an example. After frequency up-conversion, voltage is induced on coils mounted on resonators by electromagnetic induction. Due to the movement of the coils on their respective resonating cantilevers with respect to the magnet, voltage is generated on the coils and energy conversion is realized.

Abstract: The present invention relates to the unexpected finding that vessels smaller than even the smallest arteries (i.e. arterioles) thicken, become dysfunctional and cause end organ damage to tissues as diverse as the brain and the kidney. This invention provides a method to improve the structure and function of arterioles and preserve the function of end organs such as the brain and kidney. In certain embodiments, the methods involve administering to a human having thickened arterioles in brain, kidney or alveoli a peptide that ranges in length up to 30 amino acids, and that comprises a class A amphipathic helix, and bears at least one protecting group.

Abstract: Pro-drug forms of linear polyamine-bridged platinum compounds and methods for their production and use are provided. The polyamine-bridge portion of the compounds is based on spermine or spermidine, and the central amines of the polyamine-bridge are chemically bonded to labile blocking groups. The presence of the blocking groups serves to minimize the toxicity of the Pt compounds upon administration. Selective removal of the blocking groups and release of the active, unblocked species occurs upon exposure to suitable environmental conditions.

Abstract: The method and system for vehicular guidance comprises an imaging device for collecting color image data. A definer defines a series of scan line segments generally perpendicular to a transverse axis of the vehicle or of the imaging device. An image parameter evaluator determines scan line image parameter data for each of the scan line segments. An alignment detector (e.g., search engine) identifies a preferential heading of the vehicle that is generally aligned with respect to a crop feature, associated with the image data, based on the determined scan line image parameter meeting or exceeding a maximum value or minimum threshold value.

Abstract: A computer based method of biometric analysis which compares a first vector from a first biometric sample with a second vector from a second biometric sample. The vectors have at least one biometric feature. A method which compares two biometric samples. The samples form at least one cluster of at least one vector based on feature similarities between the samples. An apparatus incorporating a means for performing the method taught herein. A computer-readable medium and a propagated computer data signal transmitted via a propagation medium, with instructions which when executed by a processor, carry out the method of the present invention. A method of handwriting analysis which calculates a first metric from a first vector having at least one feature from a sample, calculates a second metric from a second vector having at least one feature from a second sample, and calculates the distance in two-dimensional feature space between metrics.

Abstract: Some embodiments of the present invention provide a pulse generator for high impedance electrodes as well as stimulation systems and components for selective stimulation and/or neuromodulation of targeted neural tissue. Targeted neural tissue may include one or more dorsal root ganglia with an electrode implanted on, in or around a dorsal root ganglia. Some other embodiments of the present invention provide methods for selective neurostimulation of one or more dorsal root ganglia as well as techniques for applying neurostimulation to the spinal cord. Still other embodiments of the present invention provide stimulation systems and components for selective stimulation and/or neuromodulation of one or more dorsal root ganglia through implantation of an electrode on, in or around a dorsal root ganglia in combination with a pharmacological agent.