Abstract: A method for detecting a gas phase constituent such as carbon monoxide, nitrogen dioxide, hydrogen, or hydrocarbons in a gas comprising oxygen such as air, includes providing a sensing material or film having a metal embedded in a catalytically active matrix such as gold embedded in a yttria stabilized zirconia (YSZ) matrix. The method may include annealing the sensing material at about 900° C., exposing the sensing material and gas to a temperature above 400° C., projecting light onto the sensing material, and detecting a change in the absorption spectrum of the sensing material due to the exposure of the sensing material to the gas in air at the temperature which causes a chemical reaction in the sensing material compared to the absorption spectrum of the sensing material in the absence of the gas. Systems employing such a method are also disclosed.

Abstract: The invention provides methods and compositions for treating and preventing a skin rash secondary to anti-epidermal growth factor receptor (EGFR) therapy, where the method comprises applying a vitamin K analog or a phosphatase inhibitor to the skin.

Abstract: A surface acoustic wave device includes a pair of reflectors and an interdigital transducer having a cross electrode having a interdigitated portion and a dummy portion and a dummy electrode. The dummy electrode has a length different from the length of the dummy portion of the cross electrode arranged adjacent to the dummy electrode.

Abstract: A method and apparatus for the use of fluorogenic probes for development of a rapid, and cost-effective determination of lead clearance following lead hazard control activities. The invention involves the use of fluorogenic chemosensors for efficient detection of lead in dust on hard surfaces at regulatory levels. The use of methods for lead visualization based on one or more of the fluorogenic type compounds would be highly beneficial to lead abatement projects. The identification of areas of high lead concentration (hotspots) can allow work to be focused on areas that have the greatest impact on clearance. Also, a rapid and cost-effective means of determining if lead clearance has been met can improve compliance with lead abatement activities. This would decrease the amount of time and materials spent in general surface cleaning and allow the elimination of isolated areas of lead concentration that may otherwise have been missed.

Abstract: The invention relates to methods of identifying inter-patient differences in genotype of PECAM-1 to diagnose and assess risk of arterial disease. It further relates to methods of identifying therapeutics agents for to treat coronary arterial disease, and to methods for determining and exploiting such differences to improve medical outcomes.

Abstract: [PROBLEMS] To provide a semiconductor element manufacturing method by which a semiconductor element having high accuracy and high function can be manufactured by controlling diffusion depth and diffusion concentration in a pn junction region with high accuracy. [MEANS FOR SOLVING PROBLEMS] A diffusion control layer (2) composed of a thin film of a substance having a smaller diffusion coefficient than that of a diffusion source (3) is formed between a surface of a substrate (1) and the diffusion source (3), and an element of the diffusion source (3) is permitted to thermally diffuse through the diffusion control layer (2). Thus, the diffusion depth and the diffusion concentration in the semiconductor region, which is formed on the surface portion of the substrate and has a conductivity type different from that of the substrate, can be highly accurately controlled, and the semiconductor element having high accuracy and high function can be manufactured.

Abstract: A device and method for measuring water and oxygen permeation rates of a protective layer in an organic electronic device are provided. The device includes: a glass substrate; a pair of electrode layers facing each other and deposited on the glass substrate; a calcium layer deposited on the glass substrate; a water and oxygen permeable substrate deposited on the calcium layer; a target protective layer of an organic electronic device, which is deposited on the water and oxygen permeable substrate; and a sealing material applied along an edge of the target protective layer, wherein one ends of the pair of electrode layers are buried in the calcium layer and the other ends are electrically connected to an external resistance measuring device.

Abstract: A radiation imaging system is configured by a collimator 30A including a detector 21 with a discrete detection pixel corresponding with a pixel and a plurality of radiation passages 31 and looks into a plurality of detectors 21 through one radiation passage 31 to set a step width of rotation around a rotation center axis X1 only for an angle ?p made by lines provided by connecting a center detector 21 of the radiation passage 31 and the adjacent two detectors 21. In the case of generating a flat plane projection image for one direction, radio-graphing is carried out on a projection image in a plurality of predetermined angle positions (??p, 0, +?p) in the circumferential direction of the rotation center axis X1 and thereby one plane projection image is obtained.

Abstract: A peptide comprising at least 5 amino acid residues and less than 15 amino acid residues, the peptide including an amino acid sequence as set forth in SEQ ID NO: 7 as well as pharmaceutical compositions, kits and methods for diagnosing and treating amyloid associated diseases.

Abstract: Phosphatidylinositol 3-kinases (PI3Ks) are known to be important regulators of signaling pathways. To determine whether PI3Ks are genetically altered in cancers, we analyzed the sequences of the P13K gene family and discovered that one family member, PIK3CA, is frequently mutated in cancers of the colon and other organs. The majority of mutations clustered near two positions within the P13K helical or kinase domains. PIK3CA represents one of the most highly mutated oncogenes yet identified in human cancers and is useful as a diagnostic and therapeutic target.

Abstract: This invention relates primarily to a novel method to manufacture single/multi/fibers carbon filaments (nano tubes) in pure form optionally with antiferromagnetic and electrical property wherein the byproduct is hydrogen gas resulting in reduction of environmental carbon emissions by at least 20%; both carbon filaments and resultant exhaust are useful products.

Abstract: In certain preferred embodiments, the present invention provides compositions and methods for the treatment of bone conditions associated with low bone density. In preferred embodiments, the present invention provides compositions and methods for the treatment of osteoprotegerin-responsive conditions.

Abstract: An organic light emitting diode (OLED) display and a method of manufacturing the same are disclosed. The OLED display includes a first pixel, a second pixel, and a third pixel that display different colors. The display includes a first electrode, a second electrode that is opposite to the first electrode, and an emission layer which is disposed between the first electrode and the second electrode. A semi-transparent member is positioned on or under the first electrode and forms a microcavity together with the second electrode. An overcoating film is positioned under the semi-transparent member. At least one of the first pixel, the second pixel, and the third pixel has embossings formed in a surface of the semi-transparent member.

Abstract: A production method is provided that enables to produce a large-sized bulk silicon carbide (SiC) crystal of high quality at low cost. A large-sized bulk silicon carbide (SiC) crystal of high quality can be obtained at a lower temperature by reacting silicon (Si) and carbon (C) produced from a lithium carbide such as dilithium acetylide (Li2C2) with each other in an alkali metal melt and thereby producing or growing a silicon carbide (SiC) crystal. FIG. 17 shows a high-resolution TEM (HR-TEM) image of the resultant 2H—SiC crystal. A preferable lithium carbide is dilithium acetylide (Li2C2). A preferable alkali metal melt is a melt of lithium alone.

Abstract: An acoustic sensor includes at least one photonic crystal structure having at least one optical resonance with a resonance frequency and a resonance lineshape. The acoustic sensor further includes a housing mechanically coupled to the at least one photonic crystal structure. At least one of the resonance frequency and the resonance lineshape is responsive to acoustic waves incident upon the housing.

Abstract: Recurrent gene fusions in prostate cancer of androgen regulated genes or housekeeping genes and ETS family member genes are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.

Abstract: In order to identify the molecules involved in esophageal carcinogenesis and those to be useful for diagnostic markers as well as targets for new drugs and immunotherapy, a cDNA microarray representing 32,256 genes was constructed to analyze the expression profiles of 19 esophageal squamous-cell carcinomas (ESCCS) purified by laser-capture microdissection. A detailed genome-wide database for sets of genes that are significantly up- or down-regulated in esophageal cancer is disclosed herein. These genes find use in the development of therapeutic drugs or immunotherapy as well as tumor markers. Additionally, genes associated with lymph-node metastasis and post-surgery recurrence are disclosed herein. Among the candidate molecular target genes, a Homo sapiens epithelial cell transforming sequence 2 oncogene (ECT2) and a cell division cycle 45, S. cerevisiae, homolog-like (CDC45L) are further characterized.

Abstract: Materials and methods for regulating gene expression using nanoparticles functionalized with antisense oligonucleotides are provided.

Abstract: A method of manipulating particles suspended within a fluid droplet using a microfluidic system including a piezo-electric substrate (1) and a wave generation means (3) for generating a wave within the piezoelectric substrate (1), and a working surface (2) through which the wave can be distributed and upon which fluid droplets (9) can be located, the method including locating one or more droplets of fluid on the working surface (2), varying the power applied to the wave generation means (3) or varying the distribution of the wave across the working surface (2), such that particles (1 1) suspended within the fluid droplet (9) are either dispersed within the droplet or concentrated in an area within the droplet in dependence on the power or wave distribution applied by the wave generation means (3) to the piezoelectric substrate (1), or to facilitate rotation of the fluid within said fluid droplets (9) located jn the path of the wave.

Abstract: The present invention provides a Hybrid GA (HGA) in which local optimization operation is performed to only a few individual with lower fitness selected from each population of widely distributed generations in genetic algorithm (GA). Since this HGA shows very powerful global searching ability even in a vast multi-dimensional parameter space with strong multi-peak feature, the present invention may efficiently determine a number of structural parameters from a little information included in X-ray diffraction circles. As a result, the present invention may determine a complicated material structure from powder specimen even though it is hard to make a single crystal specimen. Thus, the development of new materials would be highly accelerated in the field of medicines or materials, etc.