Abstract: A method of manufacturing an LED of high reflectivity includes forming a substrate; depositing an n-type GaN layer on the substrate; depositing an active layer on a first portion of the n-type GaN layer; attaching an n-type metal electrode to a second portion of the n-type GaN layer; depositing a p-type GaN layer on the active layer; forming a metal reflector on the p-type GaN layer; attaching a p-type metal electrode to the metal reflector; and attaching the p-type metal electrode and the n-type metal electrode to an epitaxial layer respectively. The metal reflector includes a transparent layer, an Ag layer, and an Au layer. The transparent layer and the Ag layer are formed by annealing in a furnace, and the Au layer is subsequently coated on the Ag layer.

Abstract: A transistor single-pole-single-throw circuit device includes at least a transistor single-pole-single-throw circuit having a first transistor and a second transistor, and an inductor capacitor (LC) resonator having an inductor and a capacitor connected in series, allowing two ends of the LC resonator connected to the first source and the first drain of the first transistor, respectively. The transistor single-pole-single-throw circuit device adopts an LC resonator having an inductor and a capacitor connected in series to connect with the first source and the first drain of the first transistor. The inductor couples and resonates with a parasitic capacitance of the transistor, to reduce signal loss due to emerged parasitic capacitance when the conventional single-pole-single-throw circuit selects a switch transistor with a larger width.

Abstract: It is intended to provide a method for producing a denatured substance of lactalbumin, particularly the substance showing a cell death inducing activity against a tumor cell, simply at a low cost. The method for producing a denatured substance of lactalbumin includes heating a mixture of domestic animal milk and oleic acid. The method of the invention can produce a useful substance as a pharmaceutical which induces cell death of a tumor cell such as solid cancer or a leukemic lymphocyte from domestic animal milk which is an extremely inexpensive raw material and has advantages that the raw material can be obtained easily, supply of the raw material is stable, the raw material is inexpensive and the like. Further, the method is industrially advantageous because it has characteristics that a large amount of the tumor cell death inducing substance can be produced by a batch reaction, a column treatment is not required and the like.

Abstract: The present invention discloses methods and devices for selectively removing anti-PEG antibodies from a patient's blood prior to administration of a PEG-conjugated therapeutic agent so as to prevent immune reactions against the PEG-conjugated therapeutic agents when the agents are administered as a therapeutic regimen. Removal of anti-PEG antibodies may be physical, in which anti-PEG antibodies are physically removed from the blood through an extracorporeal blood circuit connected to an anti-PEG antibody removal device, or functional, in which an anti-PEG inactivating agent is infused into the patient's blood stream prior to administration of the PEG-conjugated therapeutic agent. Also disclosed is a device for selectively removing anti-PEG antibodies from a blood stream and system incorporating the device.

Abstract: Provided are novel methods for making cellulose nanocomposites, comprising biosynthesis of cellulose fibrils in situ using a growth medium comprising a polymer matrix material, under conditions suitable to provide for dispersion of the fibril throughout the growth medium as the fibrils are being formed to provide a cellulose nanocomposite material or film wherein the cellulose fibrils are highly or uniformly dispersed in the cellulose nanocomposite material, and wherein fibril structure and/or nanocomposite composition is customizable. Certain method aspects further comprise removing or separating the cellulose nanocomposite material or film from the medium, and may further comprise washing the cellulose nanocomposite material or film to remove residual medium. Particular aspects further comprise freeze-drying the cellulose nanocomposite material or film, and/or further comprise forming a molded product using the cellulose nanocomposite material or film. Compositions made by the methods are provided.

Abstract: A device and method to provide a simplified wash process and controlled disintegration of a soft substance, such as a gel, are disclosed. In use, a block of, e.g., gel matrix is placed in the device and washed with a series of appropriate solutions to remove interfering contaminants. The washing liquid is removed through a deformable narrow opening in the bottom of the device, and, subsequently, the gel block is extruded through the deformable narrow opening, by a physical force, such as centrifugal force, a vacuum or positive pressure from a gas or liquid, etc., resulting in fragmentation of the gel block into a series of particles of similar size. The fragmentation of the gel results from shear forces exerted onto the gel block traveling through the deformable narrow opening in the device.

Abstract: A distributed absorbing surveillance apparatus comprising a plurality of surveillance branches at which data of a video image frame is characterised, indexed and stored locally in real-time upon capturing means browsing and searching can be conducted locally at a relatively low computational overhead upon receipt of searching instructions from a central query processor. Such a distributed surveillance apparatus also facilitates enhanced target searching speed and efficiency.

Abstract: The present invention is a feed-forward automatic-gain control amplifier (FFAGCA) for biomedical applications and associated method, the FFAGCA comprises a detector, a controller, a variable gain amplifier (VGA), an input and an output. The associated method to process various kinds of biomedical signals with the FFAGCA comprises acts of adjusting gain setting with control path and simultaneously a signal amplification with signal path.

Abstract: A method of treating a subject for a serotonergic neurotransmission dysregulation disorder, comprises administering the subject a serotonin enhancer (e.g., a serotonin reuptake inhibitor) in an amount effective to treat the disorder; and concurrently administering the subject 5-hydroxytryptophan in an amount effective to enhance the activity of the serotonin enhancer, (e.g., serotonin reuptake inhibitor). In preferred embodiments the disorder is depression, anxiety, or substance abuse.

Abstract: This document discloses, among other things, a front end circuit having a selectable center frequency. The center frequency is selected based on a control signal proportional to a phase difference between a reference frequency and an amplifier output. A resonant frequency of a tank circuit coupled to the amplifier is tuned using the control signal.

Abstract: Disclosed is an apparatus for jetting droplets using a super-hydrophobic nozzle, including a body having a chamber formed in the body to receive a predetermined amount of fluid containing liquid and particles and a nozzle formed in the side face of the body while communicating with the chamber to jet the fluid, and an actuator for generating an electric field for jetting the fluid through the nozzle, the side face of the body being of super-hydrophobic, and the actuator including an electrode located in the chamber or the nozzle or deposited on the wall surface thereof, an electrode plate spaced apart from the side face of the body at a predetermined distance with a jetting hole at a position corresponding to the nozzle, a power supply portion for applying voltage between the electrode and the electrode plate, and a control portion for controlling the power supply portion, thereby effectively realizing the initial formation of the meniscus of the fluid upon jetting through the super-hydrophobic nozzle, and in

Abstract: A vision-based augmented reality system using an invisible marker indicates an invisible marker on a target object to be tracked, such that it can rapidly and correctly track the target object by detecting the invisible marker. The augmented reality system includes a target object including an infrared marker drawn by an invisible infrared light-emitting material; a visible-ray camera for capturing an image of the TO; an infrared-ray camera for capturing an image of the IM included in the TO image; an optical axis converter for allowing the infrared-ray camera and the visible-ray camera to have the same viewing point; an image processing system for rendering a prepared virtual image to the TO image to generate a new image.

Abstract: Disclosed is a system and a method for polling in an Ether net Passive Optical Network (EPON). The system includes: multiple Optical Network Units (ONUs) for sharing optical channels of the EPON with one another and transmitting traffic; and an Optical Line Terminal (OLT) for discriminating a plurality of ONUs gaining access to the EPON among the multiple ONUs and then collecting routing information on the plurality of ONUs gaining access to the EPON, and for classifying the plurality of ONUs gaining access to the EPON into two or more ONU groups according to the collected routing information and then carrying out forming a polling cycle and allocating bandwidth on each ONU group. Therefore, a transmission idle period in a traffic channel is not only minimized, but an availability ratio of traffic channels can also be maximized.

Abstract: Nucleic acid-immunoliposome compositions useful as therapeutic agents are disclosed. These compositions preferably comprise (i) cationic liposomes, (ii) a single chain antibody fragment which binds to a transferrin receptor, and (iii) a nucleic acid encoding a wild type p53. These compositions target cells which express transferrin receptors, e.g., cancer cells. These compositions can be used therapeutically to treat persons or animals who have cancer, e.g., head and neck cancer, breast cancer or prostate cancer.

Abstract: Disclosed herein are techniques for computationally designing enzymes. These techniques can be used to design variations of naturally occurring enzymes, as well as new enzymes having no natural counterparts. The techniques are based on first identifying functional reactive sites required to promote the desired reaction. Then, hashing algorithms are used to identify potential protein backbone structures (i.e., scaffolds) capable of supporting the required functional sites. These techniques were used to design 32 different protein sequences that exhibited aldol reaction catalytic function, 31 of which are defined in the Sequence Listing. Details of these 31 different synthetic aldolases are provided, including descriptions of how such synthetic aldolases can be differentiated from naturally occurring aldolases.

Abstract: A biosensor structure and a method for fabricating the same are described. The biosensor structure for detecting at least a single cell includes a substrate with an insulating surface, a conductive layer and a plurality of capture molecules. The conductive layer is disposed on the substrate, and has a first pattern and a second pattern separated from each other. The first pattern includes a plurality of first finger configurations, and the second pattern includes a plurality of second finger configurations, so as to form interdigitated array. The capture molecules are immobilized on the conductive layer, such that the cell that is bound specifically to the capture molecules on two adjacent first and second finger configurations is detected. The biosensor structure is feasible for real-time (<3 min), specific, and quantitative targeted cell detection down to a single cell.

Abstract: A method and apparatus models one or more electromagnetic field modes of a waveguide. The method includes calculating a first matrix having a plurality of elements and having a first bandwidth using a refractive index profile of the waveguide. The plurality of elements of the first matrix represents an action of Maxwell's equations on a transverse magnetic field within the waveguide. The method further includes rearranging the plurality of elements of the first matrix to form a second matrix having a second bandwidth smaller than the first bandwidth. The method further includes shifting the second matrix and inverting the shifted second matrix to form a third matrix. The method further includes calculating one or more eigenvalues or eigenvectors of the third matrix corresponding to one or more modes of the waveguide.

Abstract: In a method of measuring a temperature value associated with melting, softening or decomposition of sample substances, an array of samples is deposited onto a support tray. The support tray is placed onto a heating device provided with temperature sensing means, the support tray is illuminated, and the array of samples is observed by a imaging device. WNle varying the temperature of the heating device, the image data from the imaging device is fed to an image recording device and temperature values associated with each feed of image data are also recorded. The image data is reviewed to detect changes in the image, such as image intensity, at each or selected sample locations, and the temperature of the heating device at an image change associated with a change in state of a sample is logged. Image processing software may be used to detect changes in the image, for example in the intensity of the image, at each sample location.

Abstract: The present invention describes the identification, isolation, cloning, and determination of the Alzheimer Related Membrane Protein (ARMP) gene on chromosome 14 and a related gene, E5-1, on chromosome 1. Normal and mutant copies of both genes are presented. Transcripts and products of these genes are useful in detecting and diagnosing Alzheimer's disease, developing therapeutics for treatment of Alzheimer's disease, as well as the isolation and manufacture of the protein and the construction of transgenic animals expressing the mutant genes.

Abstract: Colloidosomes having tunable properties, methods for making the same, and applications thereof are described. Colloidosomes described herein are responsive to certain external stimulus to alter one or more properties of the colloidosome. Methods for making colloidosomes include forming a shell of colloidal particles on a core material where the colloidal particles and the core material have attractive interactions.