Patents Assigned to University
  • Patent number: 7547885
    Abstract: A radiation detector includes a signal readout substrate. The signal readout substrate is constructed by arranging pixel units having pixel electrodes in a two-dimensional matrix form on a front surface of a substrate. On a front surface of the signal readout substrate, formed is a photoconductive layer having crystallinity. On a front surface of the photoconductive layer, formed is a contact assistance layer having conductivity. On a front surface of the contact assistance layer, formed is a common electrode. A surface area per unit region of the front surface of the contact assistance layer is smaller than a surface area per unit region of the front surface of the photoconductive layer. In addition, the contact assistance layer is formed so as to include the common electrode and so as to be included in the front surface of the photoconductive layer when viewed from the front.
    Type: Grant
    Filed: December 14, 2007
    Date of Patent: June 16, 2009
    Assignees: National University Corporation Shizuoka University, Hamamatsu Photonics K.K.
    Inventors: Haruhisa Kinoshita, Masanori Kinpara, Michiatsu Nakada, Syouji Kurebayashi, Hideyuki Suzuki, Toshiaki Kawai
  • Patent number: 7547470
    Abstract: A moisture impermeable edge reinforced wood composite structural system includes a wood composite panel having opposing faces, at least one moisture impermeable reinforcement edge, and at least one moisture impermeable reinforcement perimeter zone. The perimeter zone is a coating of a moisture impermeable reinforcement/resin matrix material which provides the structural system with improved fastener performance and reduced panel edge swell as a result of moisture exposure.
    Type: Grant
    Filed: April 28, 2006
    Date of Patent: June 16, 2009
    Assignee: University of Maine System Board of Trustees
    Inventors: Douglas J. Gardner, Stephen M. Shaler, Lech Muszynski, Ciprian Pirvu, Jungil Son
  • Patent number: 7547521
    Abstract: The present invention describes a heteromultimeric proton-gated ion channel (herein called ASIC-2S.2) with distinctive properties. Compositions and methods are provided for producing and expressing functional ASIC-2S.2 channels, composed of ASIC2A and ASIC3 subunits. The invention also provides genetically engineered expression vectors comprising the nucleic acid sequences encoding both ASIC2A and ASIC3 and host cells coexpressing both ASIC2A and ASIC3 subunits. Also provided herein are genetically engineered nucleic acids encoding chimeric proton-gated ion channels comprised of at least two different subunits, as well as expression vectors and host cells comprising said engineered nucleic acids. The invention also provides for the use of ASIC-2S.2, as well as agonists, antagonists or antibodies specifically binding ASIC-2S.2, in the diagnosis, prevention and treatment of diseases associated with expression of ASIC-2S.2.
    Type: Grant
    Filed: April 20, 2001
    Date of Patent: June 16, 2009
    Assignee: McGill University
    Inventors: Philippe Seguela, Kazimierz Babinski
  • Patent number: 7547551
    Abstract: The present invention provides an improved method for gene delivery in eukaryotic cells by electroporation, preferably in human hematopoietic cells, particular dendritic cells. The method of the invention is superior to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for gene delivery, including tumor antigen loading of dendritic cells.
    Type: Grant
    Filed: June 20, 2002
    Date of Patent: June 16, 2009
    Assignees: University of Antwerp.
    Inventors: Gerold Schuler, Zwi N. Berneman, Viggo F. I. Van Tendeloo, Peter Ponsaerts, Isolde Strobel
  • Patent number: 7547677
    Abstract: Provided is a peptide, peptide multimer or fusion protein containing such peptide which binds to the gut of sap-sucking insects, e.g., aphids. When bound, this peptide inhibits the binding of targeted virus to the insect gut. When this peptide or tandem repeat peptide is expressed (or is expressed as part of a fusion protein) in the fluids of transgenic plants, it is taken up by the insect with the sap, binds to gut receptors and thereby inhibits transmission of the virus from plant to plant via the insect vector. Thus, the use of such transgenic plants blocks or reduces the transmission of the targeted virus and others which share the peptide binding site within the insect gut among plants susceptible to the virus and thereby reduces losses due to viral infection.
    Type: Grant
    Filed: December 11, 2007
    Date of Patent: June 16, 2009
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Bryony Bonning, W. Allen Miller, Sijun Liu
  • Patent number: 7547726
    Abstract: This invention relates to crystals comprising apo-LsrB and holo-LsrB. The structure of holo-LsrB identifies a tetrahydroxytetrahydrofuran derived from 4,5-dihydroxy-2,3-pentanedione (DPD) as the active autoinducer-2 (AI-2) molecule in Salmonella typhimurium. The X-ray crystallographic data can be used in a drug discovery method. Additionally the invention provides AI-2 analogs based on this discovery as well as pharmaceutical compositions containing those analogs.
    Type: Grant
    Filed: September 16, 2005
    Date of Patent: June 16, 2009
    Assignee: The Trustees of Princeton University
    Inventors: Stephen T. Miller, Karina B. Xavier, Michiko E. Taga, Shawn R. Campagna, Martin F. Semmelhack, Bonnie L. Bassler, Frederick M. Hughson
  • Patent number: 7547449
    Abstract: The subject invention concerns a composite comprising an organic fluid-swellable, fibrous matrix, such as collagen, and a mineral phase, such as calcium carbonate or phosphate mineral phase, for use as a biomimetic of bone. In another aspect, the subject invention concerns a process for making a composite involving the inclusion of acidic polymers to a supersaturated mineralizing solution, in order to induce an amorphous liquid-phase precursor to the inorganic mineral, which is then absorbed (pulled by capillary action) into the organic matrix. Advantageously, once solidified, a high mineral content can be achieved, with the inorganic mineral crystals embedded within the collagen fibers (intrafibrillarly) and oriented such that they are aligned along the long axes of the fibers of the organic matrix, thereby closely mimicking the natural structure of bone.
    Type: Grant
    Filed: May 12, 2006
    Date of Patent: June 16, 2009
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Laurie B. Gower, Matthew J. Olszta, Elliot P. Douglas, Sivakumar Munisamy, Donna L. Wheeler
  • Patent number: 7548897
    Abstract: The Mission Centric Network Defense System (MCNDS) is a deployable network defense system that monitors network activities, generates and maintains situational awareness of operational activities, and uses this joint situational awareness of networked and operational activities to predict the mission impact of alterations and disruptions of networked resources. The MCNDS uses its predictive capability to rank information operation (IO) courses-of-action (COAs) and interpret network alarms and intrusion detections in terms of expected operational mission impact.
    Type: Grant
    Filed: October 2, 2003
    Date of Patent: June 16, 2009
    Assignee: The Johns Hopkins University
    Inventors: George R. Barrett, Susan C. Lee
  • Patent number: 7547886
    Abstract: An organic material can be used in a modified strain gauge for IR transduction, resulting in an organic IR sensor. Infrared radiation incident on the organic material modulates a displacement of the material in order to detect the presence and intensity of IR radiation. This innovative design doesn't require cooling, and is sensitive to 9 and 3 ?m—wavelengths that are emitted by mammals and forest fires, respectively. In addition, a photomechanical polymer can be used in a transistor based on a thin-film transistor (TFT), also resulting in an IR sensor. Through careful synthesis of the polymers, the photomechanical response of the transistor can be tailored to certain IR bands for detection purposes.
    Type: Grant
    Filed: July 7, 2006
    Date of Patent: June 16, 2009
    Assignee: The Regents of the University of California
    Inventors: Michael Mueller, Jim Cheng, Albert Pisano, Thomas H. Cauley, III
  • Patent number: 7548637
    Abstract: A method for detecting an object in an image includes calculating a log L likelihood of pairs of pixels at select positions in the image that are derived from training images. The calculated log L likelihood of the pairs of pixels is compared with a threshold value. The object is detected when the calculated log L likelihood is greater than the threshold value.
    Type: Grant
    Filed: April 7, 2005
    Date of Patent: June 16, 2009
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Ziyou Xiong, Thomas S. Huang, Makoto Yoshida
  • Patent number: 7547972
    Abstract: The laminated structure includes a substrate of low dielectric constant material of silicon compound and an electroless copper plating layer laminated thereon with a barrier layer. The barrier layer is interposed between the substrate and the copper layer, and the barrier layer is formed by electroless plating. And the laminated structure is characterized in that the barrier layer is formed on the substrate with a monomolecular layer of organosilane compound and a palladium catalyst which are interposed between the substrate and the barrier layer, the palladium catalyst modifies the terminal, adjacent to the barrier layer, of the monomolecular layer, and the barrier layer includes an electroless NiB plating layer which is disposed on the substrate side, and a electroless CoWP plating layer.
    Type: Grant
    Filed: September 29, 2006
    Date of Patent: June 16, 2009
    Assignee: Waseda University
    Inventors: Tetsuya Osaka, Masahiro Yoshino
  • Patent number: 7547379
    Abstract: The present claimed invention intends to provide a responsive glass membrane for ion selective electrode glass and an ion selective electrode comprising the responsive glass membrane that produces a self-cleaning function when the ultraviolet rays are irradiated although no change is brought in a composition of a sample solution as being an object to be measured and that is low in electric resistance value and superior in responsivity under an ordinary measurement environment. The responsive glass membrane for ion selective electrode is made of the titanium-containing oxide glass that contains 20˜80 mol % of titanium dioxide and lithium oxide.
    Type: Grant
    Filed: February 26, 2008
    Date of Patent: June 16, 2009
    Assignees: Horiba, Ltd., Mie University
    Inventors: Yuji Nishio, Yasukazu Iwamoto, Tadanori Hashimoto
  • Patent number: 7547472
    Abstract: A new, non-wrapping approach to functionalizing nanotubes, such as carbon nanotubes, in organic and inorganic solvents is provided. In accordance with certain embodiments, carbon nanotube surfaces are functionalized in a non-wrapping fashion by functional conjugated polymers that include functional groups. Various embodiments provide polymers that noncovalently bond with carbon nanotubes in a non-wrapping fashion. For example, various embodiments of polymers are provided that comprise a relatively rigid backbone that is suitable for noncovalently bonding with a carbon nanotube substantially along the nanotube's length, as opposed to about its diameter. In preferred polymers, the major interaction between the polymer backbone and the nanotube surface is parallel ?-stacking. In certain implementations, the polymers further comprise at least one functional extension from the backbone that are any of various desired functional groups for functionalizing a carbon nanotube.
    Type: Grant
    Filed: July 9, 2007
    Date of Patent: June 16, 2009
    Assignees: Zyvex Performance Materials, Inc., University of Pittsburgh - of the Commonwealth System of Higher Education
    Inventors: Jian Chen, Haiying Liu
  • Patent number: 7547932
    Abstract: A vertical gate-depleted single electron transistor (SET) is fabricated on a conducting or insulating substrate. A plurality of lightly doped basic materials and tunneling barriers are fabricated on top of a substrate, wherein at least two of the layers of basic materials sandwich the layers of tunneling barriers and at least two of the layers of tunneling barriers sandwich at least one of the layers of basic materials. A mesa is fabricated on top of the layers of basic materials and tunneling barriers, and has an undercut shape. An ohmic contact is fabricated on top of the mesa, and one or more gate Schottky contacts are fabricated on top of the layers of lightly doped basic materials and tunneling barriers. A quantum dot is induced by gate depletion, when a source voltage is set as zero, a drain voltage is set to be less than 0.1, and a gate voltage is set to be negative.
    Type: Grant
    Filed: November 22, 2002
    Date of Patent: June 16, 2009
    Assignee: The Regents of the University of California
    Inventors: Yaohui Zhang, Filipp A. Baron, Kang L. Wang
  • Patent number: 7547380
    Abstract: Devices for the manipulation of a suspended particle in an electric field gradient include a plurality of electrically isolated electrodes on a surface. A liquid composition is on the plurality of electrodes. The liquid composition covers the surface continuously between adjacent ones of the plurality of electrodes. The liquid composition has an exposed liquid surface for suspending a particle. The plurality of electrodes are configured to provide an electric field gradient for transporting the particle suspended in said liquid composition.
    Type: Grant
    Filed: January 12, 2004
    Date of Patent: June 16, 2009
    Assignee: North Carolina State University
    Inventor: Orlin Velev
  • Patent number: 7546650
    Abstract: A surgical table includes a horizontal patient support with a base extending therefrom and supporting the patient support at a desired height. The surgical table also includes an adjustment platform positioned upon the patient support. The adjustment platform includes a plurality of expansion members adapted to selectively adjust the relative position of the patient.
    Type: Grant
    Filed: January 20, 2006
    Date of Patent: June 16, 2009
    Assignee: Yale University
    Inventor: James J. Yue
  • Patent number: 7547294
    Abstract: An actuator for an interventional surgical procedure is described. The actuator may include an actuator body having a distal end and a proximal end. A central expandable section is located between the distal end and the proximal end. The expandable section is operable between an unactuated condition in which the expandable section is in a furled state and an actuated condition in which the expandable section is in an unfurled state. A needle is located at the expandable section. The needle is moveable in an approximately perpendicular direction relative to a central longitudinal axis of the actuator body from a position within the actuator body to a position outside of the actuator body.
    Type: Grant
    Filed: September 20, 2002
    Date of Patent: June 16, 2009
    Assignee: The Regents of The University of California
    Inventors: Kirk Patrick Seward, Albert P. Pisano
  • Patent number: 7547759
    Abstract: The present invention is directed to variants of antigens comprising folate binding protein epitopes as a composition associated with providing immunity against a tumor in an individual. The variant is effective in inducing cytotoxic T-lymphocytes but preferably not to the extent that they become sensitive to silencing by elimination, such as by apoptosis, or by energy, as in unresponsiveness.
    Type: Grant
    Filed: March 8, 2002
    Date of Patent: June 16, 2009
    Assignees: Board of Regents, The University of Texas System, Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
    Inventors: Constantin G. Ioannides, George E. Peoples, Jr.
  • Patent number: 7548910
    Abstract: A system and method for automatically extracting relevant key concepts from a free-text document and indexing the document using the extracted key concepts. The indexing mechanism applies syntactic and semantic filters to filter out irrelevant terms. The remaining terms are deemed to be key concepts for the free-text document. An input search query is compared against the key concepts extracted for the free-text document for determining whether the document satisfies the query. Prior to applying the search query, additional scenario-specific terms are added to the search query in order to improve retrieval performance. The query expansion mechanism generates a list of candidate expansion concepts, filters the list of candidate expansion concepts based on a user-entered scenario concept, and expands the input query based on the candidate expansion concepts remaining after the filtering process.
    Type: Grant
    Filed: January 28, 2005
    Date of Patent: June 16, 2009
    Assignee: The Regents of the University of California
    Inventors: Wesley W. Chu, Zhenyu Liu, Qinghua Zou
  • Patent number: D594551
    Type: Grant
    Filed: January 20, 2006
    Date of Patent: June 16, 2009
    Assignee: University of Central Florida Research Foundation
    Inventors: Danny S. Parker, Bart Hibbs