Patents Assigned to University
  • Modulating robo: ligand interactions
    Publication number: 20090155928
    Abstract: Disclosed are methods and compositions for identifying agents which modulate the interaction of Robo and a Robo ligand and for modulating the interaction of Robo and a Robo ligand. The methods for identifying Robo:ligand modulators find particular application in commercial drug screens. These methods generally comprise (1) combining a Robo polypeptide, a Slit polypeptide and a candidate agent under conditions whereby, but for the presence of the agent, the Robo and Slit polypeptides engage in a first interaction, and (2) determining a second interaction of the Robo and Slit polypeptides in the presence of the agent, wherein a difference between the first and second interactions indicates that the aget modulates the interaction of the Robo and Slit polypeptides.
    Type: Application
    Filed: August 13, 2007
    Publication date: June 18, 2009
    Applicant: The Regents of the University of California
    Inventors: Corey S. Goodman, Thomas Kidd, Katja Brose, Marc Tessier-Lavigne
  • MicroRNAs for Modulating Herpes Virus Gene Expression
    Publication number: 20090156535
    Abstract: An algorithm for identification of microRNA (miRNA) targets within viral and cellular RNA is disclosed. Also disclosed are essential herpes virus genes whose transcripts contain one or more targets of miRNAs encoded by herpes viruses or by host cells as predicted by the algorithm, and the use of such targets, miRNAs and their derivatives for modulating viral replication and latency.
    Type: Application
    Filed: September 29, 2008
    Publication date: June 18, 2009
    Applicants: The Trustees of Princeton University, The Institute For Advanced Study - Louis Bamberger and Mrs. Felix Fuld Foundation
    Inventors: Jiri Vanicek, Eain Murphy, Harlan Robins, Arnold J. Levine, Thomas Shenk
  • Thermionic electron source
    Publication number: 20090153012
    Abstract: A thermionic electron source includes a substrate, at least two electrodes, and a thermionic emitter. The electrodes are electrically connected to the thermionic emitter. The thermionic emitter has a film structure. Wherein there a space is defined between the thermionic emitter and the substrate.
    Type: Application
    Filed: October 23, 2008
    Publication date: June 18, 2009
    Applicants: Tsinghua University, HON HAI Precision Industry CO., LTD.
    Inventors: Peng Liu, Liang Liu, Kai-Li Jiang, Shou-Shan Fan
  • IRON-GOLD BARCODE NANOWIRE AND MANUFACTURING METHOD THEREOF
    Publication number: 20090155617
    Abstract: Disclosed are an Fe—Au barcode type nanowire and a method of manufacturing the same. The nanowire has a magnetic-optical multifunction and is suitable for adjusting magnetic intensity thereof. The Fe—Au nanowire has a multilayered structure, in which an iron layer and a gold layer are alternately and repeatedly formed, and is formed in a single plating bath through a pulse electro-deposition.
    Type: Application
    Filed: October 31, 2007
    Publication date: June 18, 2009
    Applicant: KOREA University, Industry & Academy Collaboration Foundation of Korea University, Industry & Academ
    Inventors: Young Keun Kim, Ju Hun Lee, Jun Hua Wu, Hong Ling Liu, Ji Ung Cho, Ji Hyun Min, Boo Hyun An, Moon Kyu Cho, Su Jung Noh
  • System And Method For Grading Electricity Distribution Network Feeders Susceptible To Impending Failure
    Publication number: 20090157573
    Abstract: A machine learning system creates failure-susceptibility rankings for feeder cables in a utility's electrical distribution system. The machine learning system employs martingale boosting algorithms and Support Vector Machine (SVM) algorithms to generate a feeder failure prediction model, which is trained on static and dynamic feeder attribute data. Feeders are dynamically ranked by failure susceptibility and the rankings displayed to utility operators and engineers so that they can proactively service the distribution system to prevent local power outages. The feeder rankings may be used to redirect power flows and to prioritize repairs. A feedback loop is established to evaluate the responses of the electrical distribution system to field actions taken to optimize preventive maintenance programs.
    Type: Application
    Filed: July 23, 2008
    Publication date: June 18, 2009
    Applicants: The Trustees Of Columbia University In The City Of New York, Conedison, Inc.
    Inventors: Roger N. Anderson, Albert Boulanger, David L. Waltz, Phil Long, Arias Marta, Philip Gross, Hila Becker, Arthur Kressner, Mark Mastrocinque, Matthew Koenig, John A. Johnson
  • Method for manufacturing a memory element comprising a resistivity-switching NiO layer and devices obtained thereof
    Publication number: 20090152526
    Abstract: The present disclosure is related to non-volatile memory devices comprising a reversible resistivity-switching layer used for storing data. The resistivity of this layer can be varied between at least two stable resistivity states such that at least one bit can be stored therein. In particular this resistivity-switching layer is a metal oxide or a metal nitride. A resistivity-switching non-volatile memory element includes a resistivity-switching metal-oxide layer sandwiched between a top electrode and a bottom electrode. The resistivity-switching metal-oxide layer has a gradient of oxygen over its thickness. The gradient is formed in a thermal oxidation step. Set and reset voltages can be tuned by using different oxygen gradients.
    Type: Application
    Filed: November 7, 2008
    Publication date: June 18, 2009
    Applicants: Interuniversitair Microelektronica Centrum (IMEC) vzw, University of South Toulon Var
    Inventors: Lorene Courtade, Judit Lisoni Reyes, Ludovic Goux, Christian Turquat, Christophe Muller, Dirk Wouters
  • Touch panel and display device using the same
    Publication number: 20090153503
    Abstract: A touch panel includes a first electrode plate and a second electrode plate separated from the first electrode plate. The first electrode plate includes a first substrate and a first conductive layer disposed on a lower surface of the first substrate. The second electrode plate includes a second substrate and a second conductive layer disposed on an upper surface of the second substrate. At least one of the first conductive layer and the second conductive layer includes a carbon nanotube layer, and carbon nanotubes in the carbon nanotube layer are arranged along a same direction. A display device adopting the touch panel includes the touch panel and a display element.
    Type: Application
    Filed: September 29, 2008
    Publication date: June 18, 2009
    Applicants: Tsinghua University, HON HAI Precision Industry CO., LTD.
    Inventors: Kai-Li Jiang, Liang Liu, Shou-Shan Fan
  • PLASMA PROCESSING APPARATUS AND METHOD THEREOF
    Publication number: 20090152243
    Abstract: [Problem] To provide a plasma processing apparatus and a method thereof, which is capable of generating plasma evenly on the lower surface of a dielectric. [Means for Solving] A plasma processing apparatus 1, in which microwave is propagated into a dielectric 32 provided on an upper surface of a processing chamber 4 via plural slots 70 formed on a lower surface of a waveguide 35 and a processing gas supplied in the processing chamber 4 is made into plasma using electric field energy of an electromagnetic field formed on the surface of the dielectric to perform plasma processing on a substrate G. The plasma processing apparatus 1, concave portions 80a to 80g having different depth are formed on a lower surface of dielectric 32. Further, the depths of the respective concave portions 80a to 80g are made different to control a plasma generation on the lower surface of the dielectric 32.
    Type: Application
    Filed: September 27, 2006
    Publication date: June 18, 2009
    Applicants: Tokyo Electron Limited, Tohoku University
    Inventors: Takahiro Horiguchi, Shinsuke Oka, Masaki Hirayama
  • DERIVATIVE N-THIOLATED 2-OXAZOLIDINONE ANTIBIOTICS
    Publication number: 20090156654
    Abstract: This invention describes the discovery and synthesis of N-thiolated 2-oxazolidinones as a new class of anti bacterial agents. These compounds can be synthesized from 2-oxazolidinones by Ndeprotection and N-sulfenylation. These new substances were found to exhibit potent anti-bacterial activity, including bacteriostatic properties against Staphylococcus spp., including methicillin resistant Staphylococcus aureus (MRSA), and Bacillus spp., including Bacillus anthracis.
    Type: Application
    Filed: December 19, 2008
    Publication date: June 18, 2009
    Applicant: University of South Florida
    Inventors: Edward Turos, Rajesh Kumar Mishra
  • BUTYROPHENONES AND SIGMA-1 RECEPTOR ANTAGONISTS PROTECT AGAINST OXIDATIVE-STRESS
    Publication number: 20090156637
    Abstract: The present invention includes compositions and methods for the protection of one or more central nervous system cells from trauma, when administered before, during or after the trauma, wherein the composition includes an effective amount of a butyrophenone, e.g., a 1-linked phenyl butyrophenone that is electronegative along the butyl chain and/or a Sigma-1 receptor antagonist.
    Type: Application
    Filed: February 23, 2009
    Publication date: June 18, 2009
    Applicant: University of North Texas Health Science Center of Fort Worth
    Inventors: John A. Schetz, James Simpkins, Jeffery Talbert
  • METHOD FOR NUCLEATING POLYMERS
    Publication number: 20090156743
    Abstract: The present invention discloses a nucleating microemulsion comprising nanovehicles, each comprising an amphiphilic shell surrounding a nucleating agent. The microemulsion is suitable for the delivery of the nucleating agents into a thermoplastic polymer, thereby allowing crystallization of the polymer.
    Type: Application
    Filed: February 27, 2007
    Publication date: June 18, 2009
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Nissim Garti, Abraham Aserin, Dima Libster
  • COMPOSITIONS COMPRISING PROMOTER SEQUENCES AND METHODS OF USE
    Publication number: 20090155913
    Abstract: Nucleic acid molecules, fragments and variants thereof having promoter activity are provided in the current invention. The invention also provides vectors containing a nucleic acid molecule of the invention and cells comprising the vectors. Methods for making and using the nucleic acid molecules of the invention are further provided.
    Type: Application
    Filed: October 29, 2008
    Publication date: June 18, 2009
    Applicant: North Carolina State University
    Inventors: Rodolphe Barrangou, Andrea Azcarate-Peril, Eric Altermann, Tri Duong, Todd R. Klaenhammer
  • FLUOROCYTIDINE DERIVATIVES AND COX-2 INHIBITORS FOR THE TREATMENT OF CANCER
    Publication number: 20090156548
    Abstract: The present invention provides, in certain embodiments, methods for the treatment of colorectal cancer comprising administering a COX-2 inhibitor and fluorocytidine derivative to a human patient. In certain embodiments, a radiation therapy is also administered to the patient.
    Type: Application
    Filed: March 2, 2007
    Publication date: June 18, 2009
    Applicant: The Board of Regents, of the University of Texas System
    Inventor: Edward H. Lin
  • Touch panel and display device using the same
    Publication number: 20090153507
    Abstract: A touch panel includes a substrate, a transparent conductive layer, and at least two electrodes. The transparent conductive layer is formed on a surface of the substrate. The transparent conductive layer includes at least two carbon nanotube layers, and each carbon nanotube layer includes a plurality of carbon nanotubes arranged along a same direction. The carbon nanotubes of adjacent carbon nanotube layers are arranged along different directions. The electrodes are electrically connected with the transparent conductive layer. Further, a display device using the touch panel is also included.
    Type: Application
    Filed: September 29, 2008
    Publication date: June 18, 2009
    Applicants: Tsinghua University, HON HAI Precision Industry CO., LTD.
    Inventors: Kai-Li Jiang, Liang Liu, Shou-Shan Fan
  • Method for producing direct in vitro flowering and viable seed from cotyledon, radicle, and leaf explants, and plants produced therefrom
    Patent number: 7547548
    Abstract: The present invention relates to a method of reprogramming plant development that allows flower buds and seeds to arise de novo, directly from a cotyledon or radicle explants or from shoots produced on a cotyledon or radicle. The present invention also provides for an improved culturing media that provide for in vitro flowering.
    Type: Grant
    Filed: May 27, 2005
    Date of Patent: June 16, 2009
    Assignee: University of Toledo
    Inventors: Sairam V. Rudrabhatla, Stephen L. Goldman
  • Metaphase donor cells for effective nuclear reprogramming in mammals
    Patent number: 7547818
    Abstract: The present invention provides methods of producing a clone non-human mammalian nuclear transfer (NT) embryo and methods for producing a cloned non-human mammal. Embodiments of the methods include introducing doner genetic material into a metaphase I oocyte; introducing donor genetic material into a non-enucleated oocyte; introducing donor genetic material obtained from a donor cell that is a metaphase into an oocyte; introducing donor genetic material into an oocyte, and naturally activating the oocyte or the NT embryo; and introducing donor genetic material obtained from a donor cell that is at late G1 phase into anoocyte.
    Type: Grant
    Filed: March 25, 2004
    Date of Patent: June 16, 2009
    Assignee: The University of Georgia research Foundation, Inc.
    Inventor: Steven Stice
  • 3D cones gradient waveform generation
    Patent number: 7548062
    Abstract: A method of performing magnetic resonance imaging is provided. Sampling requirements are used to define a three dimensional cone trajectory differential equation. The equation is solved to obtain a starting point. A search is performed by performing a plurality of cycles, where each cycle comprises selecting a point on the cone trajectory, working backward from the starting point to reduce twist, providing a failure value if it is determined that when the twist reaches zero it is not possible to return to the origin at a final velocity of zero, and providing a success value if it is determined that when the twist reaches zero it is possible to return to the origin at a final velocity of zero. A plurality of cycles is performed, where each cycle comprises applying a magnetic resonance image excitation and scanning along the calculated cone trajectory and acquiring a readout.
    Type: Grant
    Filed: March 26, 2008
    Date of Patent: June 16, 2009
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventor: Paul Gurney
  • Intracranial neural interface system
    Patent number: 7548775
    Abstract: In some preferred embodiments, without limitation, the present invention comprises an implantable, intracranial neural interface node which is an integrated and minimally invasive platform system and supports cross-modal neural interfaces to the cerebrum and other associated structures in the central nervous system. The neural interfaces comprise electrical and chemical interfaces for neural recording, electrical stimulation, chemical delivery, chemical sensing, chemical sampling, cell delivery, genetic material delivery and/or other functions of interest.
    Type: Grant
    Filed: October 21, 2004
    Date of Patent: June 16, 2009
    Assignee: The Regents of the University of Michigan
    Inventors: Daryl R. Kipke, Justin C. Williams, Jamille Hetke, Jaimie Henderson, P. Charles Garell
  • Synthesis of nano-materials in ionic liquids
    Patent number: 7547347
    Abstract: A method of synthesizing nanoparticles includes: combining at least one stabilizing agent, at least one precursor and an ionic liquid to form a reaction mixture; heating the reaction mixture to a predetermined temperature to form the nanoparticles and cause the nanoparticles to self-separate from the reaction mixture; and collecting the nanoparticles from the reaction mixture. Ionic liquid from which the nanoparticles are separated may be reused.
    Type: Grant
    Filed: May 15, 2006
    Date of Patent: June 16, 2009
    Assignee: University of Rochester
    Inventors: Hong Yang, Yong Wang
  • Switchable window based on electrochromic polymers
    Patent number: 7547658
    Abstract: Syntheses of a new blue EC monomer (ProDOT-MePro), and a new red EC monomer (ProDOP-Et2) are described. Two additional new types of EC monomers based on 3,4-alkylenedioxythiophene include fluorinated EC monomers and an EC monomer including silicon. EC polymer devices having more than one different color EC polymer to enable additional colors to be provided using subtractive color mixing are also described, as well as EC polymer devices incorporating a logo, image, or text, are generally obscured when the device is colored, but become visible when the device is not colored. Also described are EC polymer devices that include a cathodic EC polymer layer, a gel electrolyte, a counter electrode, and a reference electrode. Working prototypes of such devices exhibit significant increases in the speed of transition of the EC device from a colored state to a transparent state.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: June 16, 2009
    Assignee: University of Washington
    Inventors: Lu Liu, Chunye Xu, Susan E. Legenski, Minoru Taya