Patents Assigned to University
  • Patent number: 7549008
    Abstract: A “smart cable” that connects one or more peripheral devices to a digital media player having multiple, different types of input and/or output connections.
    Type: Grant
    Filed: July 28, 2006
    Date of Patent: June 16, 2009
    Assignee: Universal Electronics, Inc.
    Inventor: Nicholas Kalayjian
  • Patent number: 7547816
    Abstract: The invention relates to the genetic manipulation of non-human animals. More particularly, the invention relates to genetic manipulation of non-human animals to be used for xenotransplantation. The invention provides viable gene knockout swine including swine in which the ?(1,3)-galactosyltransferase gene has been disrupted, methods for making such swine, and methods of using the tissues and organs of such swine for xenotransplantation.
    Type: Grant
    Filed: December 23, 2002
    Date of Patent: June 16, 2009
    Assignees: The Curators of the University of Missouri, Immerge Biotherapeutics, Inc.
    Inventors: Billy N. Day, Robert J. Hawley, Randall S. Prather
  • Patent number: 7548278
    Abstract: A spatio-temporal noise removal method using block classification that removes noise from a third field by using first, second, and third fields which are continuously inputted. The method includes generating first, second, and third motion-compensated fields; classifying blocks of the third field into a uniform region and a non-uniform region based on a variance value of a generated difference image; performing temporal filtering over every block of the third field; performing spatio-temporal filtering over every block of the first and third motion-compensated fields and the third field and performing the temporal filtering over the every block of the third field based on spatially-filtered value; and outputting a third noise-removed field by applying a weighted value to the temporal-filtered value and the spatio-temporal-filtered value.
    Type: Grant
    Filed: December 14, 2005
    Date of Patent: June 16, 2009
    Assignees: Samsung Electronics Co., Ltd., Industry - University Cooperation Foundation Sogang Univ
    Inventors: Dong-hyuk Shin, Rae-hong Park
  • Patent number: 7547512
    Abstract: The present invention relates to a high-throughput diagnostic assay for the virus causing Severe Acute Respiratory Syndrome (SARS) in humans (“hSARS virus”). In particular, the invention relates to a high-throughput reverse transcription-PCR diagnostic test for SARS associated coronavirus (SARS-CoV). The present assay is a rapid, reliable assay which can be used for diagnosis and monitoring the spread of SARS and is based on the nucleotide sequences of the N (nucleocapsid)-gene of the hSARS virus. The present method eliminates false negative results and provides increased sensitivity for the assay. The invention also discloses the S (spike)-gene of the hSARS virus. The invention further relates to the deduced amino acid sequences of the N-gene and S-gene products of the hSARS virus and to the use of the N-gene and S-gene products in diagnostic methods. The invention further encompasses diagnostic assays and kits comprising antibodies generated against the N-gene or S-gene product.
    Type: Grant
    Filed: March 24, 2004
    Date of Patent: June 16, 2009
    Assignee: The University of Hong Kong
    Inventors: Joseph S. M. Peiris, Kwok Yung Yuen, Lit Man Poon, Yi Guan, Kwok Hung Chan, John M. Nicholls, Frederick C. Leung
  • Patent number: 7547760
    Abstract: The present invention relates to the inhibition of the function of SHP2 by both anti-SHP2 peptides and the chemical compound 4-(2-sulfaminoethyl)benzoic acid, SEBA, and SEBA derivatives binding to the phosphotyrosyl phosphatase domain of SHP2 thereby inhibiting the function of SHP2 both in vitro and in vivo. In addition, the inhibition of SHP2 may be useful as a treatment for human disease, and it has been shown that interfering with SHP2 function using the anti-SHP2 peptides and SEBA compounds reverses cell transformation and induces remission of preformed tumors in vivo demonstrating a possible treatment for cancer.
    Type: Grant
    Filed: July 3, 2006
    Date of Patent: June 16, 2009
    Assignee: West Virginia University
    Inventors: Yehenew Mekonnen Agazie, Peter M. Mannett
  • Patent number: 7547473
    Abstract: Magnetic nanoparticles and a method for producing the same are disclosed. A carboxylated polysaccharide with various functions such as chelating and ion exchange is covalently bound on the surfaces of magnetic nanoparticles. The polysaccharide-bound magnetic nanoparticles are highly stable, well dispersed, and have many advantages of high adsorption capacity, fast adsorption rate and easy magnetically manipulation. Hence, the polysaccharide-bound magnetic nanoparticles are applied to adsorb many ionic substances, and further act as an adsorbent for wastewater treatment or biochemical separation, a carrier for drugs or gene site-directed delivery, and a magnetic resonance imaging (MRI) contrast agent.
    Type: Grant
    Filed: November 18, 2005
    Date of Patent: June 16, 2009
    Assignee: National Cheng Kung University
    Inventors: Dong-Hwang Chen, Yang-Chuang Chang
  • Patent number: 7546880
    Abstract: A process for extracting hydrocarbon gases from marine sediment hydrates. In one embodiment, the process includes drilling from a sea floor into a hydrate rich subsea sediment to form at least one opening therein. Electrical heaters are inserted into the opening or openings. The hydrate rich subsea sediment is heated with the electrical heaters in order to release hydrocarbon gas therefrom. The released hydrocarbon gas is collected in an overhead receiver. The hydrocarbon gas forms hydrates again when moving through the cold sea water and inside the overhead receiver. The overhead receiver is raised to a sea depth where pressure and temperature permit the hydrates to dissociate and to release the hydrocarbon gas. The hydrocarbon gas is then gathered from the top of the overhead receiver.
    Type: Grant
    Filed: December 12, 2006
    Date of Patent: June 16, 2009
    Assignee: The University of Tulsa
    Inventors: Hong-Quan Zhang, James P. Brill, Cem Sarica
  • Patent number: 7548776
    Abstract: A method and a system are disclosed for performing fever triage. At first, a thermal image-detecting unit is used to detect a testee at a time-point and a position so as to form thermal image data. Meanwhile, a visible light image-detecting unit is used to detect the testee at the same time-point and position so as to form visible light image data. Thereafter, thermal image data are analyzed to determine if at least one fever-temperature block thereof is within a predetermined temperature range. Then, the fever-temperature block is analyzed to determine if it is corresponding to the skin portions of the visible light image data. Thereafter, if the result of the previous step is yes, then a warning signal is issued to indicate that the testee has fever.
    Type: Grant
    Filed: February 8, 2005
    Date of Patent: June 16, 2009
    Assignee: Southern Taiwan University of Technology
    Inventor: Yih-Ran Sheu
  • Patent number: 7547686
    Abstract: A new and more efficient synthesis of combretastatin A-3 (2a) was completed (8.4% overall yield) starting from methyl gallate and isovanillin with aldehyde 5 and phosphonium salt 8 as key intermediates. Conversion of combretastatin A-3 (2a) to a series of diphosphate prodrugs (lOa-lOl) containing selected anions was achieved. Both the diphosphate sodium (lOa) and potassium salts (lOc) displayed aqueous solubility in excess of 220 mg/ml at room temperature and good cancer cell line inhibitory activity.
    Type: Grant
    Filed: June 17, 2002
    Date of Patent: June 16, 2009
    Assignee: Arizona Board of Regents, a body corporate of the State of Arizona, Acting for and on Behalf of the Arizona State University
    Inventors: George R. Pettit, Mathew D. Minardi
  • Patent number: 7548650
    Abstract: One implementation provides a method to provide information associated with a previously designed component having a geometry that is similar to a geometry of a source component. In this implementation, the method includes obtaining a first set of coefficients for a non-invertible representation of the geometry of the source component, and comparing the first set of coefficients to a second set of coefficients for a non-invertible representation of the geometry of the previously designed component. If the first set of coefficients matches the second set of coefficients according to a threshold of similarity, the method further includes providing a search result associated with the previously designed component.
    Type: Grant
    Filed: June 30, 2004
    Date of Patent: June 16, 2009
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Abir Ziyad Qamhiyah, Donald Flugrad
  • Patent number: 7547275
    Abstract: A middle ear implant transducer of a hearing aid includes: first and second permanent magnets arranged such that the same poles of the first and second permanent magnets face each other; first and second vibrating members attached to both edges of the respective first and second permanent magnets; a coil enclosing the first and second permanent magnets and being separated a predetermined distance from the outer surfaces of the first and second permanent magnets between the first vibrating member and the second vibrating member; and first and second covers mounted on the outer surfaces of the first and second vibrating members, wherein the first and second vibrating members comprise couplers respectively attached to the first and second permanent magnets, rims respectively attached to the edges of the first and second covers, and support films respectively connecting the couplers to the rims and being thinner than the couplers and the rims.
    Type: Grant
    Filed: September 27, 2004
    Date of Patent: June 16, 2009
    Assignee: Kyungpook National University Industrial Collaboration Foundation
    Inventors: Jin Ho Cho, Byung Seop Song, Min Gyu Kim
  • Patent number: 7547347
    Abstract: A method of synthesizing nanoparticles includes: combining at least one stabilizing agent, at least one precursor and an ionic liquid to form a reaction mixture; heating the reaction mixture to a predetermined temperature to form the nanoparticles and cause the nanoparticles to self-separate from the reaction mixture; and collecting the nanoparticles from the reaction mixture. Ionic liquid from which the nanoparticles are separated may be reused.
    Type: Grant
    Filed: May 15, 2006
    Date of Patent: June 16, 2009
    Assignee: University of Rochester
    Inventors: Hong Yang, Yong Wang
  • Patent number: 7547658
    Abstract: Syntheses of a new blue EC monomer (ProDOT-MePro), and a new red EC monomer (ProDOP-Et2) are described. Two additional new types of EC monomers based on 3,4-alkylenedioxythiophene include fluorinated EC monomers and an EC monomer including silicon. EC polymer devices having more than one different color EC polymer to enable additional colors to be provided using subtractive color mixing are also described, as well as EC polymer devices incorporating a logo, image, or text, are generally obscured when the device is colored, but become visible when the device is not colored. Also described are EC polymer devices that include a cathodic EC polymer layer, a gel electrolyte, a counter electrode, and a reference electrode. Working prototypes of such devices exhibit significant increases in the speed of transition of the EC device from a colored state to a transparent state.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: June 16, 2009
    Assignee: University of Washington
    Inventors: Lu Liu, Chunye Xu, Susan E. Legenski, Minoru Taya
  • Patent number: 7547436
    Abstract: The present invention relates in general to methods and products for initiating an immune response against an antigen, and in particular relates to transepithelial delivery of antigens to provoke tolerance and immunity. The present invention further relates to methods and products for the transepithelial delivery of therapeutics. In particular, the invention relates to methods and compositions for the delivery of therapeutics conjugated to a FcRn binding partner to intestinal epithelium, mucosal epithelium and epithelium of the lung. The present invention further relates to the synthesis, preparation and use of the FcRn binding partner conjugates as, or in, pharmaceutical compositions for oral systemic delivery of drugs and vaccines.
    Type: Grant
    Filed: February 23, 2006
    Date of Patent: June 16, 2009
    Assignees: The Brigham and Women's Hospital, Inc., Brandeis University
    Inventors: Richard S. Blumberg, Wayne I. Lencer, Neil E. Simister
  • Patent number: 7547441
    Abstract: A method is described for detecting, visualizing, or treating cells, particularly cancerous cells, that express a uPA/uPAR complex. The method employs a PAI-2 conjugate molecule that comprises PAI-2 or a functional derivative, homologue, analogue, chemical equivalent or mimetic thereof, which PAI-2 is bound, linked, or otherwise associated with a toxin or label.
    Type: Grant
    Filed: February 23, 2001
    Date of Patent: June 16, 2009
    Assignees: PAI-2 Pty Limited, University of Wollongong, Medical Scitec Australia Pty Ltd
    Inventors: Marie Ranson, Barry John Allen, Clive Leighton Bunn
  • Patent number: 7547681
    Abstract: The invention provides compositions and methods directed to cell surface receptor antigen specific vaccines. More specifically, vaccines are provided that induce or enhance host antibody titers specific for cell surface receptor antigens and that include recombinant expression constructs containing nucleic acids encoding a target cell surface receptor antigen and one or more immune response altering molecules, or the expressed products themselves.
    Type: Grant
    Filed: January 20, 2004
    Date of Patent: June 16, 2009
    Assignee: University of Washington
    Inventors: Nathalie B Scholler, Mary L Disis, Ingegerd Hellstrom, Karl Erik Hellstrom
  • Patent number: 7548588
    Abstract: To transmit data, a set of at least 2m n×n matrices that represent an extension of a fixed-point-free group is provided. To each of 2m of the matrices is allocated one of the binary numbers from 0 to 2m?1. The data are mapped into the matrices according to the allocation. The mapped matrices are transmitted, preferably using n antennas, one antenna per row of each matrix.
    Type: Grant
    Filed: August 18, 2004
    Date of Patent: June 16, 2009
    Assignee: Ramot at Tel Aviv University Ltd.
    Inventors: Amir Averbuch, Shmuel Rosset, Yossi Zlotnick, Yossi Abarbanel, Yaniv Shmueli
  • Patent number: 7548094
    Abstract: Systems and methods for on-chip signaling are disclosed. In some embodiments, an integrated circuit having on-chip signaling between a first component and a second component includes, a differential interconnect capable of coupling the first component to the second component, a driver capable of being coupled to the first component that sends data on the differential interconnect, a receiver capable of being coupled to the second component that receives the data, and a plurality of negative impedance converters capable of being coupled to the differential interconnect that provide loss compensation.
    Type: Grant
    Filed: January 17, 2007
    Date of Patent: June 16, 2009
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Kenneth L. Shepard, Anup P. Jose
  • Patent number: 7547730
    Abstract: Activators of peroxisome proliferator-activated receptors comprising a polyprenyl compound, preferably (2E,4E,6E,10E)-3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid, as an active ingredient, and medicaments for preventive and/or therapeutic treatment of hyperlipidemia, non-insulin dependent diabetes mellitus or the like comprising a polyprenyl compound as an active ingredient.
    Type: Grant
    Filed: August 27, 2007
    Date of Patent: June 16, 2009
    Assignees: Kowa Company, Ltd., Nagasaki Prefectural and Municipal Universities Corporation
    Inventors: Yoshihiro Shidoji, Naoto Ishibashi
  • Patent number: D594552
    Type: Grant
    Filed: May 12, 2006
    Date of Patent: June 16, 2009
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventors: Danny S. Parker, Bart Hibbs