Patents Assigned to University
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Patent number: 7549008Abstract: A “smart cable” that connects one or more peripheral devices to a digital media player having multiple, different types of input and/or output connections.Type: GrantFiled: July 28, 2006Date of Patent: June 16, 2009Assignee: Universal Electronics, Inc.Inventor: Nicholas Kalayjian
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Patent number: 7547816Abstract: The invention relates to the genetic manipulation of non-human animals. More particularly, the invention relates to genetic manipulation of non-human animals to be used for xenotransplantation. The invention provides viable gene knockout swine including swine in which the ?(1,3)-galactosyltransferase gene has been disrupted, methods for making such swine, and methods of using the tissues and organs of such swine for xenotransplantation.Type: GrantFiled: December 23, 2002Date of Patent: June 16, 2009Assignees: The Curators of the University of Missouri, Immerge Biotherapeutics, Inc.Inventors: Billy N. Day, Robert J. Hawley, Randall S. Prather
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Patent number: 7548278Abstract: A spatio-temporal noise removal method using block classification that removes noise from a third field by using first, second, and third fields which are continuously inputted. The method includes generating first, second, and third motion-compensated fields; classifying blocks of the third field into a uniform region and a non-uniform region based on a variance value of a generated difference image; performing temporal filtering over every block of the third field; performing spatio-temporal filtering over every block of the first and third motion-compensated fields and the third field and performing the temporal filtering over the every block of the third field based on spatially-filtered value; and outputting a third noise-removed field by applying a weighted value to the temporal-filtered value and the spatio-temporal-filtered value.Type: GrantFiled: December 14, 2005Date of Patent: June 16, 2009Assignees: Samsung Electronics Co., Ltd., Industry - University Cooperation Foundation Sogang UnivInventors: Dong-hyuk Shin, Rae-hong Park
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Patent number: 7547512Abstract: The present invention relates to a high-throughput diagnostic assay for the virus causing Severe Acute Respiratory Syndrome (SARS) in humans (“hSARS virus”). In particular, the invention relates to a high-throughput reverse transcription-PCR diagnostic test for SARS associated coronavirus (SARS-CoV). The present assay is a rapid, reliable assay which can be used for diagnosis and monitoring the spread of SARS and is based on the nucleotide sequences of the N (nucleocapsid)-gene of the hSARS virus. The present method eliminates false negative results and provides increased sensitivity for the assay. The invention also discloses the S (spike)-gene of the hSARS virus. The invention further relates to the deduced amino acid sequences of the N-gene and S-gene products of the hSARS virus and to the use of the N-gene and S-gene products in diagnostic methods. The invention further encompasses diagnostic assays and kits comprising antibodies generated against the N-gene or S-gene product.Type: GrantFiled: March 24, 2004Date of Patent: June 16, 2009Assignee: The University of Hong KongInventors: Joseph S. M. Peiris, Kwok Yung Yuen, Lit Man Poon, Yi Guan, Kwok Hung Chan, John M. Nicholls, Frederick C. Leung
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Patent number: 7547760Abstract: The present invention relates to the inhibition of the function of SHP2 by both anti-SHP2 peptides and the chemical compound 4-(2-sulfaminoethyl)benzoic acid, SEBA, and SEBA derivatives binding to the phosphotyrosyl phosphatase domain of SHP2 thereby inhibiting the function of SHP2 both in vitro and in vivo. In addition, the inhibition of SHP2 may be useful as a treatment for human disease, and it has been shown that interfering with SHP2 function using the anti-SHP2 peptides and SEBA compounds reverses cell transformation and induces remission of preformed tumors in vivo demonstrating a possible treatment for cancer.Type: GrantFiled: July 3, 2006Date of Patent: June 16, 2009Assignee: West Virginia UniversityInventors: Yehenew Mekonnen Agazie, Peter M. Mannett
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Patent number: 7547473Abstract: Magnetic nanoparticles and a method for producing the same are disclosed. A carboxylated polysaccharide with various functions such as chelating and ion exchange is covalently bound on the surfaces of magnetic nanoparticles. The polysaccharide-bound magnetic nanoparticles are highly stable, well dispersed, and have many advantages of high adsorption capacity, fast adsorption rate and easy magnetically manipulation. Hence, the polysaccharide-bound magnetic nanoparticles are applied to adsorb many ionic substances, and further act as an adsorbent for wastewater treatment or biochemical separation, a carrier for drugs or gene site-directed delivery, and a magnetic resonance imaging (MRI) contrast agent.Type: GrantFiled: November 18, 2005Date of Patent: June 16, 2009Assignee: National Cheng Kung UniversityInventors: Dong-Hwang Chen, Yang-Chuang Chang
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Patent number: 7546880Abstract: A process for extracting hydrocarbon gases from marine sediment hydrates. In one embodiment, the process includes drilling from a sea floor into a hydrate rich subsea sediment to form at least one opening therein. Electrical heaters are inserted into the opening or openings. The hydrate rich subsea sediment is heated with the electrical heaters in order to release hydrocarbon gas therefrom. The released hydrocarbon gas is collected in an overhead receiver. The hydrocarbon gas forms hydrates again when moving through the cold sea water and inside the overhead receiver. The overhead receiver is raised to a sea depth where pressure and temperature permit the hydrates to dissociate and to release the hydrocarbon gas. The hydrocarbon gas is then gathered from the top of the overhead receiver.Type: GrantFiled: December 12, 2006Date of Patent: June 16, 2009Assignee: The University of TulsaInventors: Hong-Quan Zhang, James P. Brill, Cem Sarica
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Patent number: 7548776Abstract: A method and a system are disclosed for performing fever triage. At first, a thermal image-detecting unit is used to detect a testee at a time-point and a position so as to form thermal image data. Meanwhile, a visible light image-detecting unit is used to detect the testee at the same time-point and position so as to form visible light image data. Thereafter, thermal image data are analyzed to determine if at least one fever-temperature block thereof is within a predetermined temperature range. Then, the fever-temperature block is analyzed to determine if it is corresponding to the skin portions of the visible light image data. Thereafter, if the result of the previous step is yes, then a warning signal is issued to indicate that the testee has fever.Type: GrantFiled: February 8, 2005Date of Patent: June 16, 2009Assignee: Southern Taiwan University of TechnologyInventor: Yih-Ran Sheu
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Patent number: 7547686Abstract: A new and more efficient synthesis of combretastatin A-3 (2a) was completed (8.4% overall yield) starting from methyl gallate and isovanillin with aldehyde 5 and phosphonium salt 8 as key intermediates. Conversion of combretastatin A-3 (2a) to a series of diphosphate prodrugs (lOa-lOl) containing selected anions was achieved. Both the diphosphate sodium (lOa) and potassium salts (lOc) displayed aqueous solubility in excess of 220 mg/ml at room temperature and good cancer cell line inhibitory activity.Type: GrantFiled: June 17, 2002Date of Patent: June 16, 2009Assignee: Arizona Board of Regents, a body corporate of the State of Arizona, Acting for and on Behalf of the Arizona State UniversityInventors: George R. Pettit, Mathew D. Minardi
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Patent number: 7548650Abstract: One implementation provides a method to provide information associated with a previously designed component having a geometry that is similar to a geometry of a source component. In this implementation, the method includes obtaining a first set of coefficients for a non-invertible representation of the geometry of the source component, and comparing the first set of coefficients to a second set of coefficients for a non-invertible representation of the geometry of the previously designed component. If the first set of coefficients matches the second set of coefficients according to a threshold of similarity, the method further includes providing a search result associated with the previously designed component.Type: GrantFiled: June 30, 2004Date of Patent: June 16, 2009Assignee: Iowa State University Research Foundation, Inc.Inventors: Abir Ziyad Qamhiyah, Donald Flugrad
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Patent number: 7547275Abstract: A middle ear implant transducer of a hearing aid includes: first and second permanent magnets arranged such that the same poles of the first and second permanent magnets face each other; first and second vibrating members attached to both edges of the respective first and second permanent magnets; a coil enclosing the first and second permanent magnets and being separated a predetermined distance from the outer surfaces of the first and second permanent magnets between the first vibrating member and the second vibrating member; and first and second covers mounted on the outer surfaces of the first and second vibrating members, wherein the first and second vibrating members comprise couplers respectively attached to the first and second permanent magnets, rims respectively attached to the edges of the first and second covers, and support films respectively connecting the couplers to the rims and being thinner than the couplers and the rims.Type: GrantFiled: September 27, 2004Date of Patent: June 16, 2009Assignee: Kyungpook National University Industrial Collaboration FoundationInventors: Jin Ho Cho, Byung Seop Song, Min Gyu Kim
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Patent number: 7547347Abstract: A method of synthesizing nanoparticles includes: combining at least one stabilizing agent, at least one precursor and an ionic liquid to form a reaction mixture; heating the reaction mixture to a predetermined temperature to form the nanoparticles and cause the nanoparticles to self-separate from the reaction mixture; and collecting the nanoparticles from the reaction mixture. Ionic liquid from which the nanoparticles are separated may be reused.Type: GrantFiled: May 15, 2006Date of Patent: June 16, 2009Assignee: University of RochesterInventors: Hong Yang, Yong Wang
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Patent number: 7547658Abstract: Syntheses of a new blue EC monomer (ProDOT-MePro), and a new red EC monomer (ProDOP-Et2) are described. Two additional new types of EC monomers based on 3,4-alkylenedioxythiophene include fluorinated EC monomers and an EC monomer including silicon. EC polymer devices having more than one different color EC polymer to enable additional colors to be provided using subtractive color mixing are also described, as well as EC polymer devices incorporating a logo, image, or text, are generally obscured when the device is colored, but become visible when the device is not colored. Also described are EC polymer devices that include a cathodic EC polymer layer, a gel electrolyte, a counter electrode, and a reference electrode. Working prototypes of such devices exhibit significant increases in the speed of transition of the EC device from a colored state to a transparent state.Type: GrantFiled: October 31, 2007Date of Patent: June 16, 2009Assignee: University of WashingtonInventors: Lu Liu, Chunye Xu, Susan E. Legenski, Minoru Taya
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Patent number: 7547436Abstract: The present invention relates in general to methods and products for initiating an immune response against an antigen, and in particular relates to transepithelial delivery of antigens to provoke tolerance and immunity. The present invention further relates to methods and products for the transepithelial delivery of therapeutics. In particular, the invention relates to methods and compositions for the delivery of therapeutics conjugated to a FcRn binding partner to intestinal epithelium, mucosal epithelium and epithelium of the lung. The present invention further relates to the synthesis, preparation and use of the FcRn binding partner conjugates as, or in, pharmaceutical compositions for oral systemic delivery of drugs and vaccines.Type: GrantFiled: February 23, 2006Date of Patent: June 16, 2009Assignees: The Brigham and Women's Hospital, Inc., Brandeis UniversityInventors: Richard S. Blumberg, Wayne I. Lencer, Neil E. Simister
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Patent number: 7547441Abstract: A method is described for detecting, visualizing, or treating cells, particularly cancerous cells, that express a uPA/uPAR complex. The method employs a PAI-2 conjugate molecule that comprises PAI-2 or a functional derivative, homologue, analogue, chemical equivalent or mimetic thereof, which PAI-2 is bound, linked, or otherwise associated with a toxin or label.Type: GrantFiled: February 23, 2001Date of Patent: June 16, 2009Assignees: PAI-2 Pty Limited, University of Wollongong, Medical Scitec Australia Pty LtdInventors: Marie Ranson, Barry John Allen, Clive Leighton Bunn
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Patent number: 7547681Abstract: The invention provides compositions and methods directed to cell surface receptor antigen specific vaccines. More specifically, vaccines are provided that induce or enhance host antibody titers specific for cell surface receptor antigens and that include recombinant expression constructs containing nucleic acids encoding a target cell surface receptor antigen and one or more immune response altering molecules, or the expressed products themselves.Type: GrantFiled: January 20, 2004Date of Patent: June 16, 2009Assignee: University of WashingtonInventors: Nathalie B Scholler, Mary L Disis, Ingegerd Hellstrom, Karl Erik Hellstrom
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Patent number: 7548588Abstract: To transmit data, a set of at least 2m n×n matrices that represent an extension of a fixed-point-free group is provided. To each of 2m of the matrices is allocated one of the binary numbers from 0 to 2m?1. The data are mapped into the matrices according to the allocation. The mapped matrices are transmitted, preferably using n antennas, one antenna per row of each matrix.Type: GrantFiled: August 18, 2004Date of Patent: June 16, 2009Assignee: Ramot at Tel Aviv University Ltd.Inventors: Amir Averbuch, Shmuel Rosset, Yossi Zlotnick, Yossi Abarbanel, Yaniv Shmueli
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Patent number: 7548094Abstract: Systems and methods for on-chip signaling are disclosed. In some embodiments, an integrated circuit having on-chip signaling between a first component and a second component includes, a differential interconnect capable of coupling the first component to the second component, a driver capable of being coupled to the first component that sends data on the differential interconnect, a receiver capable of being coupled to the second component that receives the data, and a plurality of negative impedance converters capable of being coupled to the differential interconnect that provide loss compensation.Type: GrantFiled: January 17, 2007Date of Patent: June 16, 2009Assignee: The Trustees of Columbia University in the City of New YorkInventors: Kenneth L. Shepard, Anup P. Jose
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Patent number: 7547730Abstract: Activators of peroxisome proliferator-activated receptors comprising a polyprenyl compound, preferably (2E,4E,6E,10E)-3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid, as an active ingredient, and medicaments for preventive and/or therapeutic treatment of hyperlipidemia, non-insulin dependent diabetes mellitus or the like comprising a polyprenyl compound as an active ingredient.Type: GrantFiled: August 27, 2007Date of Patent: June 16, 2009Assignees: Kowa Company, Ltd., Nagasaki Prefectural and Municipal Universities CorporationInventors: Yoshihiro Shidoji, Naoto Ishibashi
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Patent number: D594552Type: GrantFiled: May 12, 2006Date of Patent: June 16, 2009Assignee: University of Central Florida Research Foundation, Inc.Inventors: Danny S. Parker, Bart Hibbs