Abstract: A technique has been developed to fabricate micro- or nanopumps based on porous alumina thin films. The main body of the nanopump consists of a porous alumina thin film (containing nano-sized channels of about 40-300 nm in diameter) with conductive surfaces (e.g. Au coating layers) on both sides of the film. Through the fabrication of nanochannels in (the alumina films) and the subsequent annealing and surface activation processes, high-efficiency micro- or nanopumps can be made. The nanofluidic flow through the nanochannels of the alumina thin films is driven by an electric field with no moving parts. The flow rate (up to 50 millilitres/(min·cm2)) of water through the alumina thin film can be continuously tuned through the intensity of the electric field, i.e., the DC electric potential applied across the nanochannels.
Type:
Grant
Filed:
June 3, 2005
Date of Patent:
June 2, 2009
Assignee:
The Hong Kong University of Science and Technology
Abstract: A computer assisted detecting and restraining system for cutting tool chatter. The system comprises a network monitor system, a signal extraction system, a chatter detection system, and a chatter restraint system. The network monitor system monitors a machine tool and receives audio caused during a cutting process. The signal extraction system extracts vibration displacement signals generated during the cutting process converts the vibration displacement signals to digital signals and transfers the digitalized signals. The chatter detection system receives the digitalized vibration displacement signals and sends a control command when the signals are high frequency signals. The chatter restraint system receives the control command and adjusts rotation rates of a spindle of the machine tool accordingly.
Abstract: The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one protein drug or bioactive agent characterized with a positive surface charge and their enhanced permeability for paracellular protein drug and bioactive agent delivery.
Type:
Grant
Filed:
May 5, 2008
Date of Patent:
June 2, 2009
Assignees:
GP Medical, Inc., National Tsing Hua University
Abstract: Methods for the diagnosis of cancer by determining the neoplastic status of a cell by probing the cell plasma membrane for the presence of nucleolin are provided, as are kits to carry out such tests.
Type:
Grant
Filed:
April 8, 2002
Date of Patent:
June 2, 2009
Assignee:
University of Louisville Research Foundation, Inc
Inventors:
Donald M. Miller, Paula J. Bates, John O. Trent, Xiaohua Xu
Abstract: The invention provides uses and methods for alleviating respiratory tract symptoms of allergy, asthma, and of viral, bacterial, fungal and parasitic infections by shifting inappropriate TH2 responses to TH1 responses by administering IL-13 receptor-targeted immunotoxins to the respiratory tract.
Type:
Grant
Filed:
February 28, 2002
Date of Patent:
June 2, 2009
Assignees:
The United States of America as represented by the Department of Health and Human Serivces, The Regents of the University of Michigan, Office of Technology Transfer
Inventors:
Raj K. Puri, Cory M. Hogaboam, Claudia Jakubzick, Steven L. Kunkel
Abstract: A method of conducting communication over one or more communication networks without making any change to the communication network infrastructure, the method comprising: selectively establishing L?2 communication paths between first and second devices, each communication path comprising one or more communication channels of one of the communication networks; splitting a communication data stream from the first device into at least L sub-streams; transmitting the sub-streams via the L communication paths; and combining the sub-streams for processing at the second device.
Abstract: An ultrasonic imaging system acquires echo signals from an object being imaged such as a moving coronary artery and the cross-correlation between echo signals is employed as an objective measure of relative object location. The method is used in a prescan procedure to determine an optimal gating window to acquire image data during a cardiac gated scan, and it is used during the scan as a real time gating signal.
Type:
Grant
Filed:
January 5, 2005
Date of Patent:
June 2, 2009
Assignee:
The Regents of the University of Michigan
Inventors:
Jonathan M. Rubin, Jeffrey Brian Fowlkes, Charles R. Meyer, Srini Tridandapani
Abstract: The present invention is a dark field illumination system including a light source which is fixed on an entrance slit of a condenser and an objective aligned with the condenser such that the objective and the condenser are adjusted to find a focus spot on a sample. The present invention essentially uses structured illumination to achieve an improved illumination system. The present invention also includes a system and method wherein the objective is coupled to an iris and aligned with the condenser such that when the iris is closed only dark field images are produced, and when the iris is open, direct entrance of light is allowed into the objective and bright field illumination is produced.
Type:
Grant
Filed:
July 14, 2006
Date of Patent:
June 2, 2009
Assignee:
Auburn University
Inventors:
Vitaly J. Vodyanoy, Oleg M. Pustovyy, Arnold Vainrub
Abstract: A reactor for carrying out a reaction between at least two fluids comprises a reactor plate (20) with a plurality of grooves or through slots (22) in which the fluids mix and react and a separable overlying reservoir plate (2) for supplying the fluids to slots (22) from reservoirs (4, 6) via slots (10) a, (10) b, with a collecting conduit or reservoir (8) and slots (10) c for the product of the reaction. Reservoir plate (2) may lie between two reactor plates, or a single reactor plate (20) may lie between two reservoir plates. Third or further reservoirs may or may not be spaced from the second reservoir (6) depending on whether more than two fluids need to be present simultaneously, or whether a second reaction is required after the first two fluids have had time to react. Means may be provided for controlling the pressure in slots (22), the pressure differential (and flow rate) along slot (22), and/or the temperature in the reservoirs (4, 6) or slots (22).
Type:
Grant
Filed:
May 9, 2003
Date of Patent:
June 2, 2009
Assignee:
University of Durham of University Office
Inventors:
Richard Dickinson Chambers, Darren Holling, Graham Sandford
Abstract: This invention relates to a compact cavity ring down spectrometer for detection and measurement of trace species in a sample gas using a tunable solid-state continuous-wave mid-infrared PPLN OPO laser or a tunable low-power solid-state continuous wave near-infrared diode laser with an algorithm for reducing the periodic noise in the voltage decay signal which subjects the data to cluster analysis or by averaging of the interquartile range of the data.
Abstract: Many applications in scientific experimentation or industrial production require the generation and shaping of charged particle bunches. A particle bunch shaper can use less expensive and smaller electrical waveform generators when the particle bunch shaper uses a nanocrystalline magnetic material. High voltage switches are examples of electrical waveform generators. A pipe with two conductive sections separated by a ceramic gap can be run through the center of cores made with the nanocrystalline magnetic material to produce the particle bunch shaper. A voltage waveform transmitted from an electrical waveform generator, through a damping circuit, and through a coupling wire running adjacent to the pipe sections can shape charged particle bunches.
Type:
Grant
Filed:
December 2, 2005
Date of Patent:
June 2, 2009
Assignee:
Universities Research Association, Inc.
Inventors:
Weiren Chou, David Wildman, Akira Takagi
Abstract: A guide toy vehicle is used for obtaining related knowledge of exhibit in a pleasant and interactive way. Guidance materials are transferred between different guidance systems through a wireless network. Thus, a user can have a wide, easy and effective learning.
Abstract: The invention is directed to methods of treating movement disorders by administering an effective amount of the compound of formula (I) to patients in need thereof. More particularly, the invention is directed to a method for treating myoclonus including administering to a patient a compound of formula (I), wherein the myoclonus is not alcohol responsive essential myoclonus with dystonia. In some embodiments, the myoclonus is posthypoxic myoclonus. The invention is also directed to a method for treating dystonia, essential tremor cerebellar tremor, a tic, or chorea, including administering to a patient a compound of formula (I).
Type:
Application
Filed:
November 9, 2005
Publication date:
May 28, 2009
Applicant:
The Trustees of Columbia University in the City of New York
Abstract: The present invention relates to a method of searching a metadata server that searches ubiquitous sensor network (USN) metadata servers in a distributed environment. The present invention stores location information on the metadata servers by using a location-server cluster and searches a location of a metadata server in which a specified resource metadata is stored, during a metadata searching request by a client. Accordingly, the present invention can provide a simple and consistent interface to the client using the metadata management servers in terms of the metadata servers and can improve the clarity of service development and can reduce the entire development costs and the maintenance and repair costs.
Type:
Application
Filed:
July 21, 2008
Publication date:
May 28, 2009
Applicants:
Electronics and Telecommunications Research Institute, Kookmin University Industry Academy Cooperation Foundation
Inventors:
Chul Su KIM, Yong Joon LEE, Jong-Hyun PARK, Sanghwan LEE, Jae-Il HAN
Abstract: The present invention relates to a method for diagnosing Alzheimer's disease and Parkinson's disease in a subject by analyzing the expression of Semaphorin 3 and downstream effectors. It also provides a method for identifying a substance useful in the prevention or treatment of Alzheimer's disease and Parkinson's disease, and a method of using such substance in the treatment of Alzheimer's disease and Parkinson's disease.
Type:
Application
Filed:
January 13, 2009
Publication date:
May 28, 2009
Applicant:
Mount Sinai School of Medicine of New York University
Abstract: Disclosed is a method of providing a poly-Si layer used in fabricating poly-Si TFT's or devices containing poly-Si layers. Particularly, a method utilizing at least one metal plate covering the amorphous silicon layer or the substrate, and applying RTA (Rapid Thermal Annealing) for light illuminating process, then the light converted into heat by the metal plate will further be conducted to the amorphous silicon layer to realize rapid thermal crystallization. Thus the poly-Si layer of the present invention is obtained.
Abstract: A system and method of vehicular wireless communication over a Dedicated Short Range Communication service band is provided. The system includes a vehicle having a navigation means, a processor, and a communication means for transmitting a message via a wireless communications link. The system includes a control channel for communicating a safety communication and a service channel for communicating a non-safety communication. The control channel is subdivided into a contention-free period having a group management interval, a service announcement interval and a safety exchange interval and a contention period having a non-safety service interval. The system further includes an integrated coordinating access point that operates in both the control channel and service channel.
Type:
Application
Filed:
November 8, 2005
Publication date:
May 28, 2009
Applicants:
Toyota Engineering & Manufacturing North America,, University of California, Berkeley
Abstract: The observed over-expression of Sp1 target genes has inspired inventors to formulate a specific strategy for correcting many gene expression defects, and thus improve clone development. The invention is based on the belief that manipulating Sp1 activity can improve cloning. Inventors believe that cloning is inefficient in large part because of the continued expression of Sp1 target genes in the early cloned embryos, which causes clones to be very unlike normal embryos, and so makes them very unhealthy. Inventors propose that if over-expression of Sp1 target genes is prevented in early stage clones, this would greatly improve cloning efficiency by making the cloned embryos healthy again.
Type:
Application
Filed:
November 25, 2008
Publication date:
May 28, 2009
Applicant:
Temple University - Of the Commonwealth System of Higher Education
Inventors:
Keith Latham, Rita Vassena, Zhiming Han
Abstract: The present invention provides a method for detecting or screening for the presence of cancer in a subject. The method comprises obtaining, providing or collecting a tissue or fluid sample (such as a urine sample) from said subject, and then determining the presence or absence of delta-catenin in said sample, or increased levels of delta-catenin in said sample as compared to a normal or control subject. The presence of delta-catenin in said sample, or increased levels of delta-catenin in said sample, indicating said subject is afflicted with or at least at risk of developing cancer.