Abstract: The present invention provides a sensor for detecting the binding of molecules to membrane surfaces. The sensor comprises a nanoparticle coated with a continuous layer of silica, and having a ligand attached thereto, for detection of an analyte in a solution. The nanoparticle can be further coated with a continuous membrane, such as a lipid bilayer.

Abstract: A system for interactive visualization of items in an online environment based on textual and quantitative properties of those items is described. End-users of the system are humans and items can be any objects such as songs, books, and other users. One aspect of the system is a process used to map an item's quantitative and textual data into a position in the visualization, e.g., a two or three dimensional space. Using transformation matrices canonical correlation analysis (CCA) and a specific item's quantitative and textual data, the system projects an item onto the visualization and uses ratings and spatial positions to assign reputation values to each end-user and their textual responses to facilitate efficient browsing and rating of items and viewing of patterns, trends, and insights as they emerge.

Abstract: Vapor wake detection is a highly advantageous method and system for detecting explosives and other illicit substances. With vapor wake detection, a canine and a handler are used; however, unlike other detection schemes, the canine leads the handler. After the handler positions the canine in a desired location, the canine detects scents in the air that come to the canine. When the canine detects a trained scent, the canine leads the handler to or follows behind the carrier of the item with the scent. Once the carrier is identified by the handler, the proper personnel are contacted. To implement vapor wake detection effectively, specific rigorous training is utilized.

Abstract: Copolymers, such as block copolymers, having at least one block that is a random copolymer of ?-caprolactone and a-carboxy-s-caprolactone are disclosed. Also described are methods of using such copolymers, such as, for example, in medical devices.

Abstract: The invention includes compositions comprising selective AKR1C3 inhibitors. The invention also includes compositions comprising bifunctional AKR1C3 inhibitors and selective androgen receptor modulators. The invention further includes methods of treatment using the compositions of the invention.

Abstract: Reduced dyes, such as hydrocyanines, deuterocyanines, and/or other deuterated dyes capable of detecting one or more reactive oxygen species are described herein. The reduced dyes exhibit little or no fluorescence due to the disrupted ? conjugation. However, upon reaction with ROS, the reduced dyes are oxidized, regenerating the extended ? conjugation and causing a substantial increase in fluorescence intensity. In many case, the oxidized dye is generally membrane impermeable. However, upon reduction, many of the reduced dyes are membrane permeable. Thus, reduced dyes can accumulate in cells and/or tissue to amplify the signal. Once inside the cell or tissue, the reduced dye is reoxidized upon reaction with ROS, and the oxidized dye again becomes membrane impermeable, trapping the dye within the cell. The reduced dyes can be used to image ROS, such as hydroxide radical and superoxide, in serum, cell cultures, tissue explants, and in vivo.

Abstract: A photovoltaic cell comprising having improved absorption of electromagnetic radiation is disclosed. The photovoltaic cell can include a rear contact, a first cell having a first band-gap energy, and a rear contact in electrical communication with an electromechanical device. The first cell can include InxGaySbz, where x+y+z=1 and z ranges from 0.00001 to 0.025. the photovoltaic cell can also include a second cell having a second band-gap energy, and a first tunnel disposed between the first and second cells. The photovoltaic cell can include at least a third cell and a second tunnel disposed between the second and third cells. The uppermost cell can include GaP or InP.

Abstract: The present invention provides multi-thiol mercaptoalkoxysilane compositions and methods of making multi-thiol mercaptoalkoxysilane compositions having the formula: wherein the R3 group, and the R4 group are independently an alkoxy, a halogen, an alkyl, an aryl, a heteroaryl, a heterocycle or derivatives thereof and n is an integer between 1 and 30.

Abstract: The present disclosure relates to methods of increasing the production of an apoplast-targeted recombinant protein in a plant tissue and to methods of increasing the purity of an apoplast-targeted recombinant protein recovered from a plant tissue.

Abstract: An exemplary embodiment provides a method for swing result deduction and posture correction. The method includes performing a coordinate transformation between a sensor frame and an earth frame, deducting the swing result according to at least one piece of sensor information and a swing result deduction analysis, and providing a posture correction advice according to at least one piece of sensor information and a posture correction analysis.

Abstract: An apparatus for installation of a tunneled vascular catheter into a patient's right atrium from the left side of their upper body. The apparatus comprises a dilator and a peel-away sheath. The dilator has a distal end portion and a proximal end portion interconnected by a shaft portion, with a lumen extending therethrough. The distal end portion is curved about 1° to about 3° from the longitudinal axis of the shaft portion. The end of the proximal end portion is provided with a flange. The total length of the dilator is about 3 cm to about 6 cm. The distal end of the peel-away sheath is provided a flange for contacting the flange at the end of the proximal end portion of the dilator. The length of the peel-away sheath is about 2.5 cm to about 4.5 cm.

Abstract: This invention provides various methods such as a method for enhancing athletic exercise performance of a subject by administering to the subject a composition comprising a physiologically acceptable carrier and an extract of tea, wherein the extract comprises at least 20% by weight of theaflavins and wherein the composition is administered in an amount effective to enhance the subject's athletic performance.

Abstract: A method for controlling inter-cell interference in a wireless communication system is disclosed. The method is performed by a base station (BS) and includes receiving information about an interference control period from a central controller; performing carrier sensing based activation competition in the interference control period, and scheduling user equipments served by the BS if the BS wins the carrier sensing based activation competition, wherein the carrier sensing based activation competition is based on a BS-specific back-off value related to a BS-specific weight.

Abstract: An isolated interleaved DC converter has a main circuit architecture integrating a transformer, a dual-phase interleaved step-up circuit, a voltage type auto charge pump circuit with a double-voltage rectifier circuit. The circuit of the invention integrates with the transformer, and combines the dual-phase interleaved boost circuit and the voltage type auto charge pump circuit at a primary side of the transformer to reduce the input current ripple. At a secondary side of the transformer, the circuit of the invention further combines the double-voltage rectifier circuit. The active switching elements can be further integrated in the dual-phase interleaved boost circuit to realize the soft switching technology while reducing EMI and the switching loss and increasing the circuit conversion efficiency.

Abstract: A compound of formula I wherein Ar1 is a bicyclic aryl or heteroaryl, which may be optionally substituted; X and Y are each independently a group of formula II: -L1-Ar2-L2-Ar3-Q-(CH2)n-NR1R2 L1 and L2 are each independently selected from NR3, C2H2, CH2, —O—, —S— and a bond; Ar2 and Ar3 are independently optionally substituted C5 or C6 aryl or heteroaryl; Q is selected from NH(C?O), NR3, S, O; n is an integer from 1 to 5; R1 and R2 are optionally substituted and are independently hydrogen, C1-7 alkyl, C3-20 heterocyclyl, or C5-20 aryl, or R1 and R2, taken together with the nitrogen atom to which they are attached, form a heterocyclic ring having from 3 to 8 ring atoms; R3 is H or C1-7 alkyl.

Abstract: A system and method for determining a patient's susceptibility to develop cardiorespiratory instability wherein physiological parameters are analyzed with respect to a dynamics systems model to produce and indicator associated with a probability that the patient will become unstable is provided.

Abstract: A set of vectorcardiogram leads attach to a patient and a signal conditioning circuit receives a plurality of analog signals from the plurality of vectorcardiogram leads. An analog to digital converter that transforms the conditioned analog signals into digital signals and a processor transforms the digital vectorcardiogram signals into electrocardiogram signals.

Abstract: Method of identifying a microRNA-recognition element and of generating microRNAs are disclosed. System and computer programs for performing such methods are disclosed. Recombinant nucleic acid molecule comprising a heterologous coding sequences and one or more MREs are also disclosed as are isolated nucleic acid molecule comprising one or more MRE sequences and being free of a coding sequence operably linked to regulatory elements. MicroRNA generated by a methods of the invention and the use of the microRNAs to downregulate gene expression are disclosed.

Abstract: The present disclosure relates to nitride semiconductor and a fabricating method thereof, and a nitride semiconductor according to an exemplary embodiment of the present disclosure includes a nitride based first and second electrode placed with a distance on a substrate, a nitride based channel layer which connects the first and second electrode, an insulating layer which covers the channel layer, and a third electrode which is formed to cover the insulating layer on the insulating layer.

Abstract: High molecular weight heparosan polymers are described, as are methods of producing and using the high molecular weight heparosan polymers.