Patent number: 9804274
Abstract: A hybrid TOF-PET/CT tomograph comprising a detection chamber, gamma radiation detectors, X-ray detectors and a movable X-ray source, wherein the gamma radiation detectors (150, 250, 350, 450, 550) and the X-ray detectors (170, 270, 370, 470, 570) surround the detection chamber (102, 202, 302, 402, 502) around the whole perimeter of the detection chamber (102, 202, 302, 402, 502), and wherein the gamma radiation detectors (150, 250, 350, 450, 550) are located closer to the longitudinal axis (115, 215, 315, 415, 515) of the detection chamber (102, 202, 302, 402, 502) than the X-ray detectors (170, 270, 370, 470, 570), and wherein the gamma radiation detectors (150, 250, 350, 450, 550) comprise polymer strips (151, 251, 351, 451, 551) made of a scintillation material having a density lower than the density of the X-ray radiation detectors (171, 271, 371, 471, 571).
Type:
Grant
Filed:
August 29, 2014
Date of Patent:
October 31, 2017
Assignee:
UNIWERSYTET JAGIELLONSKI
Inventor:
Pawel Moskal
Patent number: 9804206
Abstract: A method for measuring parameters of an analog signal to determine times at which the analog signal (S) crosses predetermined voltage thresholds (VA, VB, VC, VD), the method comprising the steps of: splitting the analog signal (S) into a number of interim signals (SA, SB, SC, SD), the number of the interim signals corresponding to the number of the preset voltage thresholds (VA, VB, VC, VD); providing an FPGA system (10) comprising differential buffers (11 A, 11 B, 11 C, 11 D) with outputs connected to a number of sequences (20A, 20B, 20C, 20D) of delay elements (21, 22, 23), the number of sequences of delay elements corresponding to the number of the preset voltage thresholds (VA, VB, VC, VD); inputting, to an input of each differential buffer (11 A, 11 B, 11 C, 11 D), one interim signal (SA, SB, SC, SD) and a reference voltage corresponding to a particular preset voltage threshold (VA, VB, VC, VD); reading, by means of vector generators (31 A, 31 B, 31 C, 31 D), assigned separately to each of the sequences
Type:
Grant
Filed:
August 29, 2014
Date of Patent:
October 31, 2017
Assignee:
UNIWERSYTET JAGIELLONSKI
Inventors:
Marek Palka, Pawel Moskal
Publication number: 20160209449
Abstract: A method for measuring parameters of an analog signal to determine times at which the analog signal (S) crosses pre-determined voltage thresholds (VA, VB, VC, VD), the method comprising the steps of: splitting the analog signal (S) into a number of interim signals (SA, SB, SC, SD), the number of the interim signals corresponding to the number of the preset voltage thresholds (VA, VB, VC, VD); providing an FPGA system (10) comprising differential buffers (11A, 11B, 11C, 11D) with outputs connected to a number of sequences (20A, 20B, 20C, 20D) of delay elements (21, 22, 23), the number of sequences of delay elements corresponding to the number of the preset voltage thresholds (VA, VB, VC, VD); inputting, to an input of each differential buffer (11A, 11B, 11C, 11D), one interim signal (SA, SB, SC, SD) and a reference voltage corresponding to a particular preset voltage threshold (VA, VB, VC, VD); reading, by means of vector generators (31A, 31B, 31C, 31D), assigned separately to each of the sequences (20A, 20B,
Type:
Application
Filed:
August 29, 2014
Publication date:
July 21, 2016
Applicant:
Uniwersytet Jagiellonski
Inventors:
Marek PALKA, Pawel MOSKAL
Publication number: 20160159790
Abstract: This invention concerns pyrroloquinoline derivatives as antagonists of 5-HT6 receptors, to methods for the preparation of these compounds and to novel intermediates useful for their synthesis. The invention also relates to the uses of such compounds and compositions, particularly their use in administering them to patients to achieve a therapeutic effect in schizophrenia, anxiety, depression, maniac depression, epilepsy, obsessive compulsive disorders, mood disorders, migraine, Alzheimer's disease, age related cognitive decline, mild cognitive impairment, sleep disorders, eating disorders, anorexia, bulimia, panic attacks, attention deficit hyperactivity disorder, attention deficit disorder, Parkinson's disease, Huntington's disease, withdrawal from abuse of cocaine, ethanol, nicotine or benzodiazepines, pain, obesity and type-2 diabetes, functional bowel disorder, Irritable Bowel Syndrome. The compounds have the general formula (XIV), wherein the symbols have the meanings given in the description.
Type:
Application
Filed:
July 25, 2013
Publication date:
June 9, 2016
Applicants:
Uniwersytet Jagiellonski, Instytut Farmakologii Polskiej Akademii Nauk, Centre National De La Recherche Scientifique, Universite de Montpellier
Inventors:
Pawel ZAJDEL, Katarzyna GRYCHOWSKA, Maciej PAWLOWSKI, Anna PARTYKA, Anna WESOLOWSKA, Andrzej J. BOJARSKI, Piotr POPIK, Tomasz KOS, Grzegorz SATALA, Frederic LAMATY, Evelina COLACINO, Jean MARTINEZ, Giles SUBRA, Xavier BANTREIL