Abstract: A method of treating root avulsion injury in a subject in need thereof includes administering to the subject a therapeutic agent that inhibits one or more of catalytic activity, signaling, and function of PTP?.

Abstract: Systems and methods for an effective solution to MR safe actuation in all MRI-guided (robot-assisted) procedures are provided. The present integrated hydraulic transmission method or system uses piston-based cylinders (101,102,201,308(C1), 309(C2), 310(C3), 402, 501) to provide continuous bi-lateral rotation with unlimited range in an MRI environment. Positional and torque control can also be achieved.

Abstract: A method and apparatus are provided for mixing highly viscous fluids to form a mixture. The mixture is created rapidly and has a high level of uniformity. The mixture is created by utilizing induced viscous fluid folding under the influence of an electric field. The electric field is introduced by connecting a nozzle dispensing the fluids in parallel to a voltage supply and grounding a collection plate located below the nozzle. When a certain voltage is applied the co-flow viscous fluids start to fold because the electric field exerts stress on the surface of the fluids, which results in changes of the geometry and dynamics of the viscous fluids. Control of the electric field provides great control over the mixture.

Abstract: A device for engagement with a bone includes a dynamically expandable tip (12), a dynamically expandable ring (40), or other dynamically expandable insert (60, 62, 401L) that reacts to forces pushing the implant into bone tissue. The tip (12), ring (40) or insert (60, 62, 401L) expands at least normal to the direction of motion, increasing contact area between the surrounding bone tissue and the material and thereby reducing the occurrence of high areas of contact stress in the adjacent bone tissue. The tip (12), ring (40) or insert (60, 62, 401L) translates forces along an axis of motion into lateral frictional forces that can resist penetration into the bone tissue without the need for additional operator or patient interaction. A method of reducing migration of the device for engagement includes the steps of providing the device and inserting the device within bone tissue.

Abstract: A power compensator for compensating voltage at a location along a power transmission line, the compensator having a controller for controlling a voltage generated across the compensator, wherein the voltage is controlled to maintain a power transmission line voltage at a value dependent on the power transmission line location.

Abstract: A computer-implemented bone-implant system evaluation method for application of mesh-free analysis of a bone-implant system for evaluation of performance of a bone-implant system for an implant implanted within the bone structure at an anatomical site, said method comprising (i) receiving a set of bone structure data set, wherein set of bone structure data includes data indicative of the bone structure at an anatomical site; (ii) inputting an implant data set and inputting the position of the implant data set, wherein the implant is selected based upon the biomechanical requirements for the anatomical site and the position and of the implant data set is indicative of the position of the implant with respect to the anatomical site, wherein implant data set includes data representative of the geometry and materials properties of the implant; (iii) creating a bone-implant model, wherein said bone implant-model includes a mesh-free model of trabecular bone at the anatomical site wherein the bone-implant model is

Abstract: A technique for displaying 3D videos creates a representation of image deformation, such as depth maps, in terms of a function for overlaying kernels with variable support and order. By optimizing the kernel type, order and support, which are allowed to be varied across different region of the deformation, it is able to approximate the image deformations in terms of the kernel parameters. Since the number of kernel parameters is usually much smaller than that of the number of pixels, this allows a significant reduction in the storage size of the image deformation.

Abstract: A method for encoding depth map image involves dividing the image into blocks. These blocks are then classified into smooth blocks without large depth discontinuities and discontinuous blocks with large depth discontinuities. In the discontinuous blocks, depth discontinuities are represented by line segments and partitions. Interpolation-based intra prediction is used to approximate and compress the depth values in the smooth blocks and partitions. Further compression can be achieved with of depth-aware quantization, adaptive de-blocking filtering, scale adaptive block size, and resolution decimation schemes.

Abstract: A plasmonic sensor with gradient nanostructures and a method of use thereof is provided. The gradient of shapes will induce different spectral responses at different region of the sensor and show different colors. When there is a change in the environment properties of a substance, such as refractive index, gas concentration or ion density changes, the sensor displays different images, e.g., redial intensity displays and radial color displays. An image recognition based method can be used to extract the environment property with high accuracy according to the sensor image.

Abstract: Described are design and generation of a set of novel cyclic lipopeptides as potential antibacterial agents. New daptomycin analogues are generated by chemical synthesis, which makes introduction of an unnatural amino acid and any modification into daptomycin possible.

Abstract: A nanostructure fabricated on a semiconductor light-emitting device induces strain in the active region. The active device includes at least one quantum heterostructure, in which the strain changes the extent of Quantum Confined Stark Effect, and thus modifies the wavelength of light emission. By mixing strain relaxation and strain induction effects there is a spectral broadening of the light emission, providing polychromatic light emission.

Abstract: Novel hybrid materials and fabrication methods thereof are provided. The novel hybrid materials can include a biodegradable polymer and a biodegradable metallic material. The hybrid material can also include a coupling agent between the biodegradable metallic material and the biodegradable polymer. A method of fabricating a hybrid material can include performing a surface treatment process on the biodegradable metallic material, and then either performing a solvent formation method or a thermal formation method.

Abstract: Compositions and methods are described in which the topical application of a toll-like receptor 7 agonist or a toll-like receptor 9 agonist at or near a subdermal vaccination site provides an enhanced response to the vaccination. The enhanced response can be an elevated antibody titer relative to an untreated but vaccinated subject, and/or development of cross-species immunity to species not present in the vaccinating composition.

Abstract: A transparent conductive film with a metal mesh embedded in a substrate and a method of fabrication thereof is provided. The metal mesh has a cap that is pressed and embedded in a substrate or a deformable material on a substrate, providing superior mechanical stability by mechanical interlocking. The embedding mechanism also provides superior chemical and environmental stability. A fabrication method is provided and includes a vacuum-free and low-cost process for large-volume manufacturing of the transparent conductive film with tunable performance.

Abstract: The present invention relate to methods and codecs for image and video compression. Embodiments of the present invention include a novel shape-adaptive model-based codec (SAM) that supports binary shapes as well as matte and soft segmentation image compression by decomposing input shapes into deterministic and stochastic components for flexible lossy and lossless coding. The present invention can provide inter/intra prediction and flexibly adapts between lossy and lossless modes with various parameters for compression quality control. The compression module can also be adapted with numerous other compression techniques.

Abstract: It is proposed a Method and System for Global Motion Estimation and Compensation. The system operates on two depth maps which contain a reference depth map and a current depth map as well as their associated texture images if available. The system executes four major steps which are feature detection (step 1), global motion compensation (GMC) (step 2), major moving objects (MMO) detection and the estimation of their motion parameters denoted as major motion parameters (MMPs) (step 3), and local motion compensation (LMC) of macroblocks or other coding/prediction units (step 4). The output of the system is the global motion parameters (GMPs), major moving objects (MMOs) and MMPs, the local motion vectors (LMVs), and the coding modes.

Abstract: Compounds, pharmaceutical compositions, and methods for treatment of microbial infections are provided. The compounds can potentiate the therapeutic effects of one or more antimicrobial agents when co-administered. The compounds have antivirulence properties. Pharmaceutical compositions including the compounds and a pharmaceutically acceptable carrier are provided. The pharmaceutical composition can further include at least one antibiotic, such as, Gentamicin, amikacin, kanamycin, neomycin, spectinomycin, neamine or any combination thereof. The compounds and compositions can be used to treat or prevent microbial infections.

Abstract: The invention pertains to amphiphilic dendrimers complexed with Bcl3 siRNA. The amphiphilic dendriplexes described herein are biodegradable and exhibit enhanced siRNA delivery. The amphiphilic dendriplexes containing Bcl3 siRNA inhibit cancer cell/tumor growth in vitro and in vivo without toxicity. Accordingly, an embodiment of the invention provides a method of treating a cancer, particularly, nasopharyngeal carcinoma, by administering to a subject in need thereof, a therapeutic amount of amphiphilic dendrimers complexed with Bcl3 siRNA. Pharmaceutical compositions containing the amphiphilic dendrimers complexed with Bcl3 siRNA are also provided.

Abstract: A technique for displaying 3D videos creates a representation of image deformation, such as depth maps, in terms of a function for overlaying kernels with variable support and order. By optimizing the kernel type, order and support, which are allowed to be varied across different region of the deformation, it is able to approximate the image deformations in terms of the kernel parameters. Since the number of kernel parameters is usually much smaller than that of the number of pixels, this allows a significant reduction in the storage size of the image deformation.

Abstract: Original or compressed Auxiliary Data, including possibly major depth discontinuities in the form of shape images, partial occlusion data, associated tuned and control parameters, and depth information of the original video(s), are used to facilitate the interactive display and generation of new views (view synthesis) of conventional 2D, stereo, and multi-view videos in conventional 2D, 3D (stereo) and multi-view or autostereoscopic displays with reduced artifacts. The partial or full occlusion data includes image, depth and opacity data of possibly partially occluded areas to facilitate the reduction of artifacts in the synthesized view. An efficient method is used for extracting objects at partially occluded regions as defined by the auxiliary data from the texture videos to facilitate view synthesis with reduced artifacts.