Patents Assigned to ViaCyte
  • Publication number: 20170022474
    Abstract: Disclosed herein are cell cultures comprising dorsal and/or ventral PDX1-positive foregut endoderm cells and methods of producing the same. Also disclosed herein are cell populations comprising substantially purified dorsal and/or ventral PDX1-positive foregut endoderm cells as well as methods for enriching, isolating and purifying dorsal and/or ventral PDX1-positive foregut endoderm cells from other cell types. Methods of identifying differentiation factors capable of promoting the differentiation of dorsal and/or ventral PDX1-positive foregut endoderm cells, are also disclosed.
    Type: Application
    Filed: October 11, 2016
    Publication date: January 26, 2017
    Applicant: ViaCyte, Inc.
    Inventors: Kevin Allen D'Amour, Alan D. Agulnick, Susan Eliazer, Emmanuel E. Baetge
  • Publication number: 20160355787
    Abstract: Disclosed herein are cell cultures and enriched cell populations of endocrine precursor cells, immature pancreatic hormone-expressing cells and mature pancreatic hormone-expressing cells. Also disclosed herein are methods of producing such cell cultures and cell populations.
    Type: Application
    Filed: June 3, 2016
    Publication date: December 8, 2016
    Applicant: ViaCyte, Inc.
    Inventors: Kevin A. D'Amour, Anne Bang, Emmanuel E. Baetge
  • Patent number: 9506034
    Abstract: The present disclosure relates to compositions and methods comprising cell surface markers for hES-derived cells, in particular, endoderm lineage cells including pancreatic endoderm-type cells, derived from hES cells.
    Type: Grant
    Filed: April 30, 2015
    Date of Patent: November 29, 2016
    Assignee: ViaCyte, Inc.
    Inventors: Olivia Kelly, Anne Bang
  • Publication number: 20160340645
    Abstract: Disclosed herein are methods of identifying one or more differentiation factors that are useful for differentiating cells in a cell population comprising definitive endoderm cells into cells which are capable of forming tissues and/or organs that are derived from the gut tube.
    Type: Application
    Filed: May 2, 2016
    Publication date: November 24, 2016
    Applicant: ViaCyte, Inc.
    Inventors: Kevin Allen D'Amour, Alan D. Agulnick, Susan Eliazer, Emmanuel E. Baetge
  • Patent number: 9499795
    Abstract: Disclosed herein are cell cultures comprising dorsal and/or ventral PDX1-positive foregut endoderm cells and methods of producing the same. Also disclosed herein are cell populations comprising substantially purified dorsal and/or ventral PDX1-positive foregut endoderm cells as well as methods for enriching, isolating and purifying dorsal and/or ventral PDX1-positive foregut endoderm cells from other cell types. Methods of identifying differentiation factors capable of promoting the differentiation of dorsal and/or ventral PDX1-positive foregut endoderm cells, are also disclosed.
    Type: Grant
    Filed: August 9, 2013
    Date of Patent: November 22, 2016
    Assignee: ViaCyte, Inc.
    Inventors: Kevin Allen D'Amour, Alan D. Agulnick, Susan Eliazer, Emmanuel E. Baetge
  • Publication number: 20160250262
    Abstract: Disclosed herein are methods for cryopreserving, hibernation and room temperature storage of PEC aggregates, implantable semipermeable devices and the VC combination product.
    Type: Application
    Filed: September 4, 2015
    Publication date: September 1, 2016
    Applicant: ViaCyte, Inc.
    Inventors: Alan Agulnick, Laura Martinson, Evert Kroon, Michael Scott, Chad Green
  • Patent number: 9222069
    Abstract: Disclosed herein are cell cultures comprising PDX1-positive endoderm cells and methods of producing the same. Also disclosed herein are cell populations comprising substantially purified PDX1-positive endoderm cells as well as methods for enriching, isolating and purifying PDX1-positive endoderm cells from other cell types. Methods of identifying differentiation factors capable of promoting the differentiation of endoderm cells, such as PDX1-positive foregut endoderm cells and PDX1-negative definitive endoderm cells, are also disclosed.
    Type: Grant
    Filed: January 2, 2014
    Date of Patent: December 29, 2015
    Assignee: ViaCyte, Inc.
    Inventors: Kevin Allen D'Amour, Alan D. Agulnick, Susan Eliazer, Emmanuel E. Baetge
  • Publication number: 20150297294
    Abstract: Embodiments herein describe tools and instruments for holding, transferring, delivering, deploying an implantable device and methods and means of aseptically storing and shipping the implantable device including but not limited to a device case for protecting, housing and filling the device, a surgical sizer for preparing the implantable site, a deployer for transferring the implantable device from the device case and delivering or deploying the implantable device at the prepared implantable site.
    Type: Application
    Filed: April 16, 2014
    Publication date: October 22, 2015
    Applicant: ViaCyte, Inc.
    Inventors: Vincent So, Erik Olson, Michael Scott, Chad Green, Giacomo Strollo, Gustavo Prado, Craig McGreevy, Laura Martinson, Donald Koenig
  • Patent number: 9132226
    Abstract: The present invention relates to methods for encapsulating pancreatic progenitors in a biocompatible semi-permeable encapsulating device. The present invention also relates to production of human insulin in a mammal in response to glucose stimulation.
    Type: Grant
    Filed: May 24, 2013
    Date of Patent: September 15, 2015
    Assignee: ViaCyte, Inc.
    Inventors: Laura Martinson, Chad Green, Evert Kroon, Emmanuel Edward Baetge
  • Patent number: 9109245
    Abstract: Disclosed herein are cell culture compositions, for example, pancreatic cell culture compositions, derived from dedifferentiated human reprogrammed pluripotent stem cells, such as induced pluripotent stem (iPS) cells, and methods for producing and using such cell culture compositions.
    Type: Grant
    Filed: February 6, 2013
    Date of Patent: August 18, 2015
    Assignee: ViaCyte, Inc.
    Inventors: Alan D. Agulnick, Olivia Kelly, Yuki Ohi, Allan Robins, Thomas Schultz
  • Patent number: 9045736
    Abstract: The present disclosure relates to compositions and methods comprising cell surface markers for hES-derived cells, in particular, endoderm lineage cells including pancreatic endoderm-type cells, derived from hES cells.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: June 2, 2015
    Assignee: ViaCyte, Inc.
    Inventors: Olivia Kelly, Anne Bang
  • Patent number: D718468
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: November 25, 2014
    Assignee: ViaCyte, Inc.
    Inventors: Vincent So, Laura Martinson, Chad Green, Michael Scott
  • Patent number: D718469
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: November 25, 2014
    Assignee: ViaCyte, Inc.
    Inventors: Vincent So, Laura Martinson, Chad Green, Michael Scott
  • Patent number: D718470
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: November 25, 2014
    Assignee: ViaCyte, Inc.
    Inventors: Vincent So, Laura Martinson, Chad Green, Michael Scott
  • Patent number: D718471
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: November 25, 2014
    Assignee: ViaCyte, Inc.
    Inventors: Vincent So, Laura Martinson, Chad Green, Michael Scott
  • Patent number: D718472
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: November 25, 2014
    Assignee: ViaCyte, Inc.
    Inventors: Vincent So, Laura Martinson, Chad Green, Michael Scott
  • Patent number: D720469
    Type: Grant
    Filed: March 7, 2013
    Date of Patent: December 30, 2014
    Assignee: ViaCyte, Inc.
    Inventors: Chad Green, Vincent So, Laura Martinson, Michael Scott
  • Patent number: D726306
    Type: Grant
    Filed: December 12, 2011
    Date of Patent: April 7, 2015
    Assignee: Viacyte, Inc.
    Inventor: Chad Green
  • Patent number: D726307
    Type: Grant
    Filed: December 12, 2011
    Date of Patent: April 7, 2015
    Assignee: Viacyte Inc.
    Inventor: Chad Green
  • Patent number: D728095
    Type: Grant
    Filed: December 12, 2011
    Date of Patent: April 28, 2015
    Assignee: Viacyte, Inc.
    Inventor: Chad Green