Abstract: A medical system for ablating a tissue site with real-time monitoring during an electroporation treatment procedure. A pulse generator generates a pre-treatment (PT) test signal prior to the treatment procedure and intra-treatment (IT) test signals during the treatment procedure. A treatment control module determines impedance values from the PT test signal and IT test signals and determines a progress of electroporation and an end point of treatment in real-time based on the determined impedance values while the treatment progresses.

Abstract: Aspects of direct current (DC)-DC converters with an integrated matrix transformer and multiphase current doubler rectifiers are described. In some examples, a DC-DC converter can include a matrix transformer that has multiple magnetically integrated transformer components that are magnetically integrated using transformer components that share a top plate and a bottom plate. A multiphase current doubler rectifier can include multiple synchronous rectifiers corresponding to the plurality of transformer components of the matrix transformer.

Abstract: The present invention concerns a novel leg mechanism for quadrupedal locomotion. This design engages a linkage to couple assembly that only requires a single degree of actuation. The topological arrangement of the system produces a foot trajectory that is well-suited for dynamic gaits including trot-running, bounding, and galloping.

Abstract: The present disclosure relates to the intelligent distribution of data for robotic, autonomous, and similar systems. To reduce the impact of multi-agent coordination on networked systems embodiments are disclosed that include the use of action-based constraints which yield constrained-action POMDP (CA-POMDP) models, and probabilistic constraint satisfaction for the resulting infinite-horizon finite state controllers. To enable constraint analysis over an infinite horizon, an unconstrained policy is first represented as a finite state controller (FSC). A combination of a Markov chain Monte Carlo (MCMC) routine and a discrete optimization routine can be performed on the finite state controller to improve probabilistic constraint satisfaction of the finite state controller, while minimizing impact to a value function.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for training and deploying machine-learned communication over multi-input-multi-output (MIMO) channels.

Abstract: The present disclosure concerns a Gas-Assisted Microbubble Extraction (GAME) system with an innovative dispersion module that can be used to efficiently separate and purify base metals and rare earth elements from various sources. The GAME system utilizes a three phase system of a gas phase, an organic phase, and an aqueous phase to efficiently extract low concentration metals from a solution.

Abstract: Various examples of an integrated parallel matrix transformer and inductor are disclosed herein. In one aspect, the transformer includes a first magnetic core having a first set of pillars of a first transformer and a second set of pillars of a second transformer and a second magnetic core having a first and second inductor pillar. The first and second magnetic cores can be separate or integrated into one core. The transformer also includes a planar winding structure. The planar winding structure may include a primary winding and a plurality of secondary windings. The primary winding can be configured to equally divide a primary current. The primary winding can extend a number of turns to conduct half of the primary current around the first inductor pillar and the first set of pillars and to conduct half of the primary current around the second inductor pillar and the second set of pillars.

Abstract: Described here are blocky PEEK copolymers and corresponding synthesis methods. It was surprisingly found that synthesis of blocky PEEK copolymers in a non-solvent environment with respect to PEEK produced blocky PEEK copolymers with high degrees of functionalization and crystallinity. The blocky PEEK copolymers had an increased blocky structure, relative to corresponding PEEK copolymer synthesized with other known methods. Moreover, membranes formed from the blocky PEEK polymers are particularly desirable in fuel cell applications. For example, the membranes formed from the blocky PEEK polymers had surprisingly large ion conductivities as well as significantly improved chemical and thermal resistance, at least in part, to the improved functionalization and crystallinity.

Abstract: A method of thermodynamic assessment of flow through a turbomachine having a compressor, comprising: receiving sensor readings from a plurality of acoustic sensors located about an intake for the turbomachine upstream of the compressor; and receiving pressure and stagnation temperature readings for the flow into the intake. A static temperature is determined for the flow into the intake and an average velocity of the flow over a flow area of the intake upstream of the compressor using the acoustic sensor readings. A mass flow rate of the flow through the intake is determined using the average velocity of the flow and the stagnation pressure.

Abstract: The present invention relates to poly(amide imide) (PAI) precursor polymers which can for example be used in Vat photopolymerization processes like lithographic processes for the photofabrication of three-dimensional (3D) articles. The invention further relates to polymer compositions including these poly(amide imide) (PAI) precursor polymers. Still further, the invention relates to vat photopolymerization methods to form three-dimensional (3D) objects that incorporate the aforementioned polymer compositions.

Abstract: An exoskeleton system and associated components are described herein. The exoskeleton system assists a user in lifting and/or bending to perform various operations. Components of the exoskeleton system can include a force device, a release mechanism, and a leg differential system. The force device includes a gas spring and a compression spring to store and release energy to assist a user of the exoskeleton system, the force device having a smooth force profile with no initial loading. The release mechanism disengages and re-engages the force device when actuated by a user. The leg differential system enables walking while wearing the exoskeleton system and equally loads different force devices of the exoskeleton system when a user's legs are displaced relative to one another.

Abstract: A flow machine having a flow passage and an air flow measurement system comprising a plurality of acoustic sensors. The acoustic sensors comprise at least one acoustic transmitter configured to transmit an acoustic waveform through the airflow passing through the flow passage to an acoustic receiver. At least one of the acoustic sensors is rotatable relative to one or more other acoustic sensor.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for training and deploying machine-learned identification of radio frequency (RF) signals.

Abstract: A system and method for extracting recyclable material from an object. The system has a station for receiving the object, a station that prepares the object's cover for removal, a station that removes the cover from the object, a station that positions the object with the cover removed for loading, and a station that has one or more extraction devices configured to engage the object and remove the recyclable material therefrom and has one or more collection areas for receiving the removed recyclable material.

Abstract: Hydrophobic particles such as coal and hydrophobized mineral fines can be readily separated from hydrophilic impurities by forming agglomerates in water using a hydrophobic liquids such as oil. The agglomerates of hydrophobic particles usually entrap large amounts of water, causing the moisture of the recovered hydrophobic particles to be excessively high. This problem can be overcome by dispersing the hydrophobic agglomerates in a hydrophobic liquid that can be readily recycled. The dispersion can be achieved using specially designed apparatus and methods that can create a turbulence that can help destabilize the agglomerates in a recyclable hydrophobic liquid and facilitate the dispersion.

Abstract: A turbomachine having an air flow measurement system. The system comprises a plurality of acoustic sensors upstream of a compressor of the turbomachine. The acoustic sensors are configured to transmit acoustic waveforms through an intake airflow to further acoustic sensors. The acoustic sensors are located in a single plane and mounted at angular spacing about a central axis of an intake.

Abstract: Methods for treating tissue with irreversible electroporation and immunotherapy are described. The methods include placing a probe in tissue within a human body, wherein the probe has at least a first electrode, applying a plurality of electrical pulses through the first electrode and a second electrode, causing irreversible electroporation (IRE) of the tissue within a target ablation zone, and administering one or more exogenous agents into the tissue within the target ablation zone or to the human, thereby stimulating or otherwise modulating an immune system response within the body.

Abstract: A method and apparatus for evaluating the chemical composition of airborne particles by sequentially collecting and analyzing airborne particles in-situ. The method includes: collecting particles; enlarging the particles through water condensation; accelerating the enlarged particles onto a surface to collect enlarged particles; and analyzing the enlarged particles by: isolating the surface; passing a carrier gas over the surface; heating the surface to thermally desorb collected particles into the carrier gas; transporting this evolved vapor into detectors; and assaying the evolved vapor as a function of a desorption temperature. The apparatus includes: a sample flow inlet; a condensational growth tube; a collection and thermal desorption (CTD) cell; a carrier gas source; a heater coupled to the CTD; one or more gas detectors; and a controller configured to operate valves, the heater, the growth tube, and the CTD cell in at least an in-situ sequential collection mode and analysis mode.

Abstract: The disclosure provides compounds of Formula (I-A) and (I-B) and the pharmaceutically acceptable salts thereof. The variables, R, R2, R3, X1, X2, X3, Y1, Y, and Z are defined herein. Certain compounds of Formula (I-A) and (I-B) act as selective mitochondrial protonophore uncouplers that do not affect plasma membrane potential. These compounds are useful for treating or decreasing the risk of conditions responsive to mitochondrial uncoupling, such as cancer, obesity, type II diabetes, fatty liver disease, insulin resistance, Parkinson's disease, ischemia reperfusion injury, heart failure, non-alcoholic fatty liver disease (NALFD), and non-alcoholic steatohepatitis (NASH), Because mitochondrial uncouplers decrease the production of reactive oxygen species (ROS), which are known to contribute to age-related cell damage, the compounds are useful for increasing lifespan. Compounds and salts of Formulae (I-A) and (I-B) are also useful for regulating glucose homeostasis or insulin action in a patient.

Abstract: In various aspects, reinforced composite filaments, methods of making reinforced composite filaments, and methods of producing reinforced composite filament are all provided herein. The reinforced composite filaments can include a thermoplastic polymer matrix having dispersed therein reinforcing fibers composed of a thermotropic liquid crystalline polymer. In some aspects, the thermoplastic polymer matrix is chosen such that a processing temperature for the thermoplastic polymer matrix is below a melting temperature of the thermotropic liquid crystalline polymer. In some aspects, the thermotropic liquid crystalline polymer is chosen such that a solidification temperature of the thermotropic liquid crystalline polymer is below an upper processing temperature of the thermoplastic polymer matrix. The filaments can be used for fused deposition manufacturing of a variety of parts, especially for the automotive and other industries.