Abstract: An accommodating contact lens comprises a control device, which comprises one or more eyelid engagement structures. The eyelid engagement structures are configured to move with the eyelid relative to the contact lens. The eyelid engagement structure is coupled to the eyelid and to the accommodating contact lens, which may comprise a fluidic module having inner and outer fluid reservoirs. The eyelid engagement structure is configured to respond to the narrowing or widening of the eyelid fissure, moving a fluid in or out of the inner reservoir to accommodate near or far vision.

Abstract: Embodiments of the present invention provide a backlight module and a liquid crystal display device. The backlight module comprises a light bar, a light guide plate and a reflector sheet. The light guide plate and the reflector sheet are adhered to each other. An anti-reflection structure is provided on at least one side of the light guide plate and/or the reflector sheet. The anti-reflection structure is used for reducing light reflected by the reflector sheet which is emitted from the light sources. The anti-reflection structure includes anti-reflection structures. A first anti-reflection structure is located on one side of the light guide plate and/or the reflector sheet close to the light bar, while a second anti-reflection structure is located on other sides of the light guide plate and/or the reflector sheet. The present invention may improve the luminescence uniformity of the backlight module.

Abstract: The present invention relates to an ophthalmic device with a retinal vascularization monitoring system and associated methods. In some embodiments, the ophthalmic device can be a contact lens with a retinal vascularization monitoring system that can be used to monitor temporal changes of a pulsating vessel forming part of the retinal vascularization. Further, the retinal vascularization monitoring system may include elements for delivering a signal, including an audible and/or visual message, to the user that can be useful for identifying abnormal conditions such as a cardiac failure without delay. The audible and/or visual messages can be signals communicated to the user using one or both of the ophthalmic device and a wireless device in communication with the ophthalmic device.

Abstract: A communication system for a vehicle includes a vehicle speed sensor configured to emit a periodic function with a parameter correlated to the speed of the vehicle, an acceleration monitoring system, a braking system engagement detector to detect a braking status of the vehicle, an alerting device capable of signaling other drivers of a deceleration condition of the vehicle, and a control device. The acceleration monitoring system is configured to compute the acceleration of the vehicle from variations in the parameter of the periodic function of the vehicle speed sensor and to output a deceleration status of the vehicle. The control device is coupled to the acceleration monitoring system, the braking system engagement detector, and the alerting device, wherein the acceleration monitoring system sends signals to the control device and the control device operates the alerting device in a manner dependent on the deceleration status of the vehicle.

Abstract: A system and method for identifying a custom contact lens for a patient. The method includes receiving as input results from a bare eye examination of a patient including at least a measured sphere power; receiving as input a target or actual measured sphere power of a selected fitting lens; receiving as input results of an over-refraction examination of a patient wearing the fitting lens, wherein the results of the over-refraction examination include at least a measured sphere power; calculating the power delivered by the fitting lens on the patient's eye based on input received from the bare eye examination and over-refraction examinations; calculating an Effectiveness Ratio using the calculated power delivered by the fitting lens and the target or actual measured sphere power of the fitting lens; and calculating a custom lens power for the patient using the Effectiveness Ratio and measured sphere power from the bare eye examination.

Abstract: A bicycle seat assembly (10) includes a bicycle seat (12) including a front portion (12N) and a rear portion (12R) and mounting platform (16) attachable to a bicycle seat post (22) or seat post adaptor of a bicycle (40). One portion of the bicycle seat (12) releasably attaches to a portion of the mounting platform (16) and another portion of the bicycle seat (12) releasably attaches to another portion of the mounting platform (16).

Abstract: The object of providing a device for reversibly attaching an implant to an eye, with which the implant can be attached in a simple way to the eye and can if necessary be detached or removed from the eye, is achieved according to the present invention by means of a device for attaching an implant by means of a pin that comprises a substantially elongated shaft, wherein the implant includes an implant film for contacting living tissue or nerves in the visual system of the eye and the implant film has an opening through which the shaft of the pin can be at least partially inserted, characterised in that the device includes a holding element that can be arranged on the shaft of the pin so that the holding element engages on the shaft of the pin and is fixed in an attachment position to the pin.

Abstract: The invention relates to a method and apparatus for calculating a laser shot file for use in an excimer laser comprising the steps of providing information with respect to a desired ablation profile, calculating the shot density of the desired ablation profile, using a cost function for placing laser shots of the excimer laser on grid positions wherein a threshold value is determined based on the calculated shot density of the desired ablation profile.

Abstract: The present invention provides a pharmaceutical composition containing hemoglobin-based therapeutic agent for treating cancer. The hemoglobin moiety can target cancer cells and the therapeutic moiety (i.e. active agent/therapeutic drug) can kill the cancer cells efficiently. The hemoglobin-based therapeutic agent used in the present invention can be used in the treatment of various cancers such as pancreatic cancer, leukemia, head and neck cancer, colorectal cancer, lung cancer, breast cancer, liver cancer, nasopharyngeal cancer, esophageal cancer, prostate cancer, stomach cancer and brain cancer. The composition can be used alone or in combination with other therapeutic agent(s) such as chemotherapeutic agent to give a synergistic effect on cancer treatment, inhibiting metastasis and/or reducing recurrence. The presently claimed hemoglobin-based 5FU-two-dye conjugate and/or hemoglobin-based 5FU-one-dye conjugate can also be used in live-cell imaging and diagnostic imaging.

Abstract: A support assembly and a display device are provided. The support assembly comprises a support frame (3) and a carrier frame (1) provided at an upper end of the support frame (3). The carrier frame (1) comprises a lower connecting member (12) and an upper connecting member (11) which are connected through a rotating shaft (13). The lower connecting member (12) is fixed to the upper end of the support frame (3), and the upper connecting member (11) comprises an engagement structure. This support assembly is used to improve the detachability between the support assembly and the display.

Abstract: The present invention provides a power supply circuit for supplying power for a display device, the display device comprising a standby module and a plurality of functional modules, the power supply circuit comprising a power supply module; a plurality of transformer modules, receiving a power voltage provided by the power supply module, and converting the power voltage into working voltages provided to the plurality of functional modules; and a switch module, connected between the power supply module and the plurality of transformer modules, for controlling the power supply module to provide the power voltage to the plurality of transformer modules, wherein the power supply module supplies power to the standby module directly, and supplies power to the plurality of functional modules through the plurality of transformer modules.

Abstract: Contact lenses incorporate high plus or add power profiles that at least one of slow, retard or preventing myopia progression and minimize halo effect. The lens includes a center zone with a negative power for myopic vision correction; and at least one treatment zone surrounding the center zone, the at least one treatment zone having a power profile that increases from an outer margin of the center zone to a positive power within the at least one treatment zone of greater than +5.00 D.

Abstract: Systems and methods for extracting an image of a physical object constructed of for example bricks are presented. The method and system may detect boundaries and edges of a background using an edge detection operator, perform a perspective transformation calculation to compute a corrected virtual grid that is substantially aligned with the physical object's image, locate a color calibration palette in the digital image and extract color value information for pixels of the color calibration palette, and discern bricks as part of the physical object's image, the discernment being based in part on a determination of the brick's color compared to the color palette and the background color, the discerned bricks forming the extracted image. A computer readable medium may include instructions causing a system to extract an image of a physical object constructed of bricks according to the method.

Abstract: A comprehensive multi-mode system for performing ophthalmic laser surgery on selected tissue inside an eye includes a laser unit for generating and focusing a laser beam to perform Laser Induced Optical Breakdown (LIOB) at a focal point in selected tissue. Also included is a selector for defining an operational mode according to characteristics of the tissue to be altered by LIOB. In combination, the operational mode specifies value ranges for configuration parameters for a pulsed femtosecond laser beam, establishes a base reference datum in the eye, and identifies a scanning procedure for the focal point of the laser beam to customize the system for a particular surgical procedure. A computer that is connected to the laser unit is responsive to the selector for implementing the operational mode.

Abstract: The invention discloses a backlight, a backlight module and a display device, belonging to the field of display technology. The backlight includes a plurality of LED lamps, a flexible circuit board for supplying power to the LED lamps and a supporting plate for supporting the flexible circuit board, wherein the flexible circuit board is arranged below the LED lamps, and the supporting plate is arranged below the flexible circuit board and is in a bent shape. In the present invention, by designing the supporting plate to be in a bent shape, it is no longer required to have to employ the existing linear backlight with a single structure, and meanwhile, the contact area between the supporting plate and air is enlarged to improve the heat dissipation effect of the backlight.

Abstract: A module for use with a mobile device to measure an aberration of a patient's eye includes a light shaft having a proximal end and a distal end. The light shaft includes a first plurality of optical components arranged to direct light along a first light path to the proximal end, and a second plurality of optical components arranged to direct light along a second light path to the distal end. A connector at the distal end includes at least one guide component for positioning the distal end adjacent to a light detector and a light source of the mobile device. When the distal end is positioned adjacent to the light detector and the light source, the first plurality of optical components directs light along the first light path and the second plurality of optical components directs light along the second light path.

Abstract: A timing device for indicating the passage of a duration of time is disclosed. The timing device and system, in accordance with the embodiments of the invention, comprise an electrochemical component which generates a visual and/or audio indication of the passage of time. The timing device further comprises a compensating element, such as a varistor, a thermistor and/or combinations thereof. The compensating element regulates the response of the device with respect to changes in temperature. The timing device is configured to indicate the passage of a single duration of time or comprises zones that are activated in a range of prescribed times and individually or collectively indicate the passage of time or the passage of a range of times.

Abstract: A system for identifying a landmark for use in autonomous vehicle navigation is provided. The system includes at least one processor programmed to receive at least one identifier associated with the landmark; associate the landmark with a corresponding road segment; update an autonomous vehicle road navigation model relative to the corresponding road segment to include the at least one identifier associated with the landmark; and distribute the updated autonomous vehicle road navigation model to a plurality of autonomous vehicles. The at least one identifier is determined based on acquisition, from a camera associated with a host vehicle, of at least one image representative of an environment of the host vehicle; analysis of the at least one image to identify the landmark in the environment of the host vehicle; and analysis of the at least one image to determine the at least one identifier associated with the landmark.

Abstract: A system for autonomously navigating a vehicle is disclosed. The system may include at least one processor and the at least one processor may be programmed to receive from a rearward facing camera, at least one image representing an area at a rear of the vehicle and analyze the at least one rearward facing image to locate in the image a representation of at least one landmark. The at least one processor may be further programmed to determine at least one indicator of position of the landmark relative to the vehicle and determine a forward trajectory for the vehicle based, at least in part, upon the indicator of position of the landmark relative to the vehicle. Additionally, the at least one processor may be programmed to cause the vehicle to navigate along the determined forward trajectory.