Abstract: A vehicle headlight comprising at least one lighting module mounted on a support. The module comprises a base with a mounting surface inclined backward and toward the top of the headlight. The support comprises a corresponding mounting surface. Positioning means with sliders are provided on these surfaces so as to be able to extract the module and fit it by a translational movement in a direction contained within the plane of the mounting surfaces. The housing comprises a removable portion positioned in the extension of the module in the direction of translation of the positioning means with sliders. The wall of the housing comprises precuts on the circumference of the removable portion. This arrangement makes is possible to easily replace a bulky lighting module such as that of a headlight with style functions.

Abstract: A timing device for indicating the passage of a duration of time is disclosed. The timing device and system, in accordance with the embodiments of the invention, comprise an electrochemical component which generates a visual and/or audio indication of the passage of time. The timing device further comprises a compensating element, such as a varistor, a thermistor and/or combinations thereof. The compensating element regulates the response of the device with respect to changes in temperature. The timing device is configured to indicate the passage of a single duration of time or comprises zones that are activated in a range of prescribed times and individually or collectively indicate the passage of time or the passage of a range of times.

Abstract: A non-chemical sanitation system for a body of water comprises a floating base, an internal hydro-electric power generator, and one or more sanitizing mechanisms electrically powered by the hydro-electric power generator, where the hydro-electric power generator derives its energy from water pressure produced by a pool pump. In some embodiments, the one or more non-chemical sanitizing mechanisms comprise one or more ultraviolet LED lights. In some embodiments, the one or more non-chemical sanitizing mechanisms comprise one or more ionizers. In some embodiments, the system is connected to a filter pipe and filter of a pool and the hydro-electric power generator is placed within the path of water flowing to the pool filter in order to generate power and power the one or more sanitizing mechanisms.

Abstract: Systems and methods of verifying the results of an initial image recognition process are presented. A verification engine can receive a set of candidate images corresponding to the results of an image recognition process performed on a captured query image. The verification engine can determine an appropriate verification technique to apply to the images of the candidate set, and classify, re-rank or otherwise re-organize the candidate set such that the best match from the candidate set is confirmed as a proper match.

Abstract: A method for fabricating high-density masks for non-planar or three-dimensional substrates utilizes a mandrel having one or more precision forms machined therein. Once the mandrel with one or more forms is fabricated, one or more mask blanks may be constructed thereon. The final masks may be cut from one or more mask blanks.

Abstract: The present invention provides a pharmaceutical composition containing a hemoglobin-based oxygen carrier for treating cancer, preventing recurrence and metastasis of cancerous tumor. The composition can be used alone or in combination with at least one chemotherapeutic agent such as 5FU, Bortezomib, doxorubicin, cisplatin, or any combination thereof. The hemoglobin-based oxygen carrier in the composition is capable of targeting a surface receptor expressed on cancerous cells and facilitating the uptake of both hemoglobin-based oxygen carrier and the chemotherapeutic agent by the cancerous cells via a receptor-mediated mechanism. The hemoglobin-based oxygen carrier inhibits the expression of hypoxic response elements such as HIF1 ?, VEGF, ET1, VHL, etc. The pharmaceutical composition of the present invention is also useful for inducing the apoptosis or cell death of a type of self-renewing and tumor-initiating cells called cancer stem cells which are located in the hypoxic niche of a cancerous tumor.

Abstract: A system having one or more lenticular units and more supplementary parts without lenticular properties. The lenticular units consist of lenticular plates that are capable of visualizing various clinically relevant examination objects. In all the examination positions, the system may visualize a fixation area that is shown alone or together with clinically relevant examination objects targeted at the examination of clinically relevant visual functions. Supplementary parts with various optical properties may be fixed or be moved relative to the lenticular units. Various clinically relevant examination objects may be visualized for the right eye and the left eye in that the examination objects of the system are provided with different colors or light polarizations and using eyeglasses with a differently colored glass for the right eye and the left eye or with polarization filters with a different direction for the right eye and the left eye.

Abstract: In general, in some embodiments, the disclosure provides a method that includes making a subjective refraction of a person to determine information about the person's vision, making a wavefront measurement of one or both of the person's eyes to determine information about the optical properties of one or both of the person's eyes (e.g., aberrations), calculating a prescription for the person based on the information about the person's vision and the information about the optical properties of one or both of the person's eyes, and outputting the prescription.

Abstract: In one aspect, the invention relates to hydrolysis-resistant silicone compounds. In particular, disclosed are sterically hindered hydrolysis-resistant silicone compounds and improved purity hydrolysis-resistant silicone compounds. Also disclosed are processes for making hydrolysis-resistant silicone compounds; the products of the disclosed processes; compositions and polymers comprising the disclosed compounds and products of the disclosed processes; and ophthalmic lenses, for example contact lenses, intraocular lenses, artificial cornea, and spectacle lenses, comprising the disclosed compositions, disclosed polymers, disclosed compounds, and products of the disclosed processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: In one aspect, the invention relates to hydrolysis-resistant silicone compounds. In particular, disclosed are sterically hindered hydrolysis-resistant silicone compounds and improved purity hydrolysis-resistant silicone compounds. Also disclosed are processes for making hydrolysis-resistant silicone compounds; the products of the disclosed processes; compositions and polymers comprising the disclosed compounds and products of the disclosed processes; and ophthalmic lenses, for example contact lenses, intraocular lenses, artificial cornea, and spectacle lenses, comprising the disclosed compositions, disclosed polymers, disclosed compounds, and products of the disclosed processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: The present disclosure relates to compositions, methods and devices for treating, reducing or preventing one or more eye disorders, particularly dry eye disorders, in a subject by administering an amount of one or more fatty acids and/or fatty acid esters therapeutically effective to inhibit lipase activity while permitting bacterial growth or without substantially altering the dynamic microbial community of the eye. Typically, the fatty acids and/or fatty acid esters are C8 to C16 fatty acids and/or fatty acid esters.

Abstract: The present invention is directed to an energizable ophthalmic lens with a smartphone event indicator, wherein the ophthalmic lens may wirelessly receive smartphone event data from a smartphone. The energizable ophthalmic lens may comprise energizable components encapsulated by the soft biocompatible portion or may comprise a media insert that may encapsulate the components. The media insert may be included in ophthalmic lens. The ophthalmic lens may include a verification mechanism, wherein a pairing with a specified smartphone may limit wireless communication to communication between the two specified devices. The receipt of smartphone event data may activate an indicator in the ophthalmic lens. The ophthalmic lens may allow for user response to the notification of the smartphone event. The response may trigger an internal action within the ophthalmic lens, or the ophthalmic lens may transmit response data to the smartphone, triggering an action in the smartphone.

Abstract: A pupil position and convergence detection system for an ophthalmic lens comprising an electronic system is described herein. The pupil position and convergence detection system is part of an electronic system incorporated into the ophthalmic lens. The electronic system includes one or more batteries or other power sources, power management circuitry, one or more sensors, clock generation circuitry, control algorithms and circuitry, and lens driver circuitry. The pupil position and convergence detection system is utilized to determine pupil position and use this information to control various aspects of the ophthalmic lens.

Abstract: In a first exemplary embodiment of the present invention, an automated, computerized method is provided for processing an image. According to a feature of the present invention, the method comprises the steps of providing an image file depicting an image, in a computer memory, providing a multi-class classifier trained to identify edges in an image relative to computer actions to be taken in respect to the respective edges, determined as a function of illumination effects in the image and utilizing the multi-class classifier to classify edges in the image, for identification of computer actions to be taken in respect to the edges in the image.

Abstract: An electronic or powered ophthalmic lens includes one or more systems having one or more batteries or other power sources, power management circuitry, one or more sensors, clock generation circuitry, control algorithms and circuitry, and lens driver circuitry. These systems may change the state of the powered ophthalmic lens. In systems having one or more sensors, a decision making process is required to substantially reduce the possibility of changing the state of the powered ophthalmic lens based upon inaccurate, incomplete or erroneous information supplied by the sensors, changing physiologic conditions , as well as noise and/or interference from internal and external sources.

Abstract: Light-emitting devices and displays with improved performance are disclosed. A light-emitting device includes an emissive material disposed between a first electrode, and a second electrode. Various embodiments include a device having a peak external quantum efficiency of at least about 2.2%; a device that emits light having a CIE color coordinate of x greater than 0.63; a device having an external quantum efficiency of at least about 2.2 percent when measured at a current density of 5 mA/cm2. Also disclosed is a light-emitting device comprising a plurality of semiconductor nanocrystals capable of emitting red light upon excitation, wherein the device has a peak luminescent efficiency of at least about 1.5 lumens per watt. Also disclosed is a light-emitting device comprising a plurality of semiconductor nanocrystals capable of emitting red light upon excitation, wherein the device has a luminescent efficiency of at least about 1.

Abstract: Various non-limiting embodiments of the present disclosure relate to ophthalmic devices comprising photochromic materials comprising a reactive substituent. For example, the present disclosure contemplates ophthalmic devices comprising photochromic materials, such as photochromic naphthopyrans and indeno-fused naphthopyrans having a reactive substituent comprising a reactive moiety linked to the photochromic naphthopyran by one or more linking groups. In certain non-limiting embodiments, the reactive moiety comprises a polymerizable moiety. In other non-limiting embodiments, the reactive moiety comprises a nucleophilic moiety. Other non-limiting embodiments of the present disclosure relate to methods of making the photochromic ophthalmic device, wherein the photochromic ophthalmic devices comprise the photochromic naphthopyrans described herein.

Abstract: The present invention is directed to anti-microbial cleanser compositions comprising linalool, hinokitiol and dipropylene glycol. The present invention further provides methods for using these compositions to maintain eyelid hygiene, to treat an ocular disorder or to clean a skin surface. The cleanser compositions of the present invention can be in the form of a foam, gel or liquid.