Patents Assigned to Warner-Lambert Company
  • Fast dissolving orally consumable films
    Patent number: 7025983
    Abstract: Physiologically acceptable films, including edible films, are disclosed. The films include a water soluble film-forming polymer such as pullulan. Edible films are disclosed that include pullulan and antimicrobially effective amounts of the essential oils thymol, methyl salicylate, eucalyptol and menthol. The edible films are effective at killing the plaque-producing germs that cause dental plaque, gingivitis and bad breath. The film can also contain pharmaceutically active agents. Methods for producing the films are also disclosed.
    Type: Grant
    Filed: April 18, 2001
    Date of Patent: April 11, 2006
    Assignee: Warner-Lambert Company LLC
    Inventors: Sau-Hung Spence Leung, Robert S. Leone, Lori D. Kumar, Neema Kulkarni, Albert F. Sorg
  • Method of treating tinnitus
    Patent number: 7026505
    Abstract: The invention relates to a method of treating tinnitus by administering an alpha2delta ligand such as, for example, a compound of Formula and pharmaceutically acceptable salts thereof, wherein R1 is hydrogen or straight or branched lower alkyl, and n is an integer of from 4 to 6.
    Type: Grant
    Filed: January 29, 2003
    Date of Patent: April 11, 2006
    Assignee: Warner-Lambert Company
    Inventors: David James Dooley, David Juergen Wustrow
  • 2-thia-1,6,8-triaza-naphthalene-2,2-dioxides are kinase inhibitors
    Patent number: 7026313
    Abstract: The present invention provides 2-thia-1,6,8-triaza-naphthalene-2,2-dioxide inhibitors of cyclin-dependent kinases, uses thereof and pharmaceutical compositions thereof. These compounds are useful for treating cell proliferative disorders, such as cancer, atherosclerosis, and restenosis. These compounds are potent inhibitors of kinases such as cyclin-dependent (cdks) and growth factor-mediated kinases.
    Type: Grant
    Filed: January 21, 2003
    Date of Patent: April 11, 2006
    Assignee: Warner-Lambert Company
    Inventor: Joseph Thomas Repine
  • Pregabalin lactose conjugates
    Patent number: 7022678
    Abstract: In accordance with the present invention, there is provided pregabalin lactose conjugate compounds. Also provided as part of the present invention is a novel method of central nervous system disorders or diseases including seizure disorders, pain, depression, anxiety, sleep disorders, consumptive disorders, psychosis, tardive dyskinesia, Huntington's disease, or Parkinson's disease in a subject by administering to the subject a pharmaceutically effective amount of a pregabalin lactose conjugate.
    Type: Grant
    Filed: January 28, 2002
    Date of Patent: April 4, 2006
    Assignee: Warner-Lambert Company
    Inventors: Timothy Robert Hurley, Michael James Lovdahl, Brian Tobias
  • 2-(4-Pyridyl)amino-6-dialkoxyphenyl-pyrido[2,3-d]pyrimidin-7-ones
    Patent number: 7022711
    Abstract: This invention provides antiangiogenic compounds of the Formula (I), which are useful for treating diseases, resulting from uncontrolled cellular proliferation such as cancer, atherosclerosis, rheumatoid arthritis, and psoriasis.
    Type: Grant
    Filed: July 20, 2001
    Date of Patent: April 4, 2006
    Assignee: Warner-Lambert Company
    Inventors: James Marino Hamby, Sylvester Klutchko, James Bernard Kramer
  • 2-(4-bromo or 4-iodo phenylamino) benzoic acid derivatives
    Patent number: 7019033
    Abstract: Phenylamino benzoic acid, benzamides, and benzyl alcohol derivatives of the formula where R1, R2, R3, R4, R5, and R6 are hydrogen or substituent groups such as alkyl, and where R7 is hydrogen or an organic radical, and Z is COOR7, tetrazolyl, CONR6R7, or CH2OR7, are potent inhibitors of MEK and, as such, are effective in treating cancer and other proliferative diseases such as inflammation, psoriasis and restenosis, as well as stroke, heart failure, and immunodeficiency disorders.
    Type: Grant
    Filed: December 10, 2002
    Date of Patent: March 28, 2006
    Assignee: Warner-Lambert Company
    Inventors: Stephen Douglas Barrett, Alexander James Bridges, Donna Reynolds Cody, Annette Marian Doherty, David Thomas Dudley, Alan Robert Saltiel, Mel Conrad Schroeder, Haile Tecle
  • Stabilization of quinapril using magnesium oxide
    Patent number: 7015232
    Abstract: The present invention is directed to ACE inhibitor-containing compositions stabilized by the presence of magnesium oxide. Preferably, the ACE inhibitor, quinapril, is protected from certain forms of degradation when prepared in a pharmaceutical composition consisting essentially of magnesium oxide as the stabilizing agent. The presence of magnesium oxide also lends itself to favorable processing conditions during the manufacture of ACE inhibitor-containing compositions, especially processing by wet granulation.
    Type: Grant
    Filed: April 22, 2002
    Date of Patent: March 21, 2006
    Assignee: Warner-Lambert Company, LLC
    Inventors: Jane Ellen Daniel, Michael Ray Harris, Gerard Clifford Hokanson, Jay Weiss
  • Pyridine matrix metalloproteinase inhibitors
    Patent number: 7015237
    Abstract: Selective MMP-13 inhibitors are pyridine derivatives of the formula or a pharmaceutically acceptable salt thereof, wherein: R1 and R2 independently are hydrogen, halo, hydroxy, C1–C6 alkyl, C1–C6 alkoxy, C2–C6 alkenyl, C2–C6 alkynyl, NO2, NR4R5, CN, or CF3; E is independently O or S; A and B independently are OR4 or NR4R5; R4 and R5 independently are H, C1–C6 alkyl, C2–C6 alkenyl, C2–C6 alkynyl, (CH2)n aryl, (CH2)n cycloalkyl, (CH2)n heteroaryl, or R4 and R5 when taken together with the nitrogen to which they are attached complete a 3- to 8-membered ring containing carbon atoms and optionally containing a heteroatom selected from O, S, or NH, and optionally substituted or unsubstituted; n is an integer of from 0 to 6.
    Type: Grant
    Filed: May 10, 2004
    Date of Patent: March 21, 2006
    Assignee: Warner-Lambert Company
    Inventors: Nicole Chantel Barvian, David Thomas Connor, Patrick Michael O'Brien, Daniel Fred Ortwine, William Chester Patt, Michael William Wilson
  • Sulfonamide derivatives
    Patent number: 7009052
    Abstract: The present invention is directed to a new class of 6-sulfonamide quinoline and chromene derivative and to their use as androgen antagonists.
    Type: Grant
    Filed: March 16, 2004
    Date of Patent: March 7, 2006
    Assignee: Warner Lambert Company LLC
    Inventors: Daniel Y. Du, Matthew Colin Thor Fyfe, Martin James Procter, Karen Lesley Schofield, Vilasben Kanji Shah, Geoffrey Martyn Williams
  • Fish gelatin compositions containing a hydrocolloid setting system
    Patent number: 7008639
    Abstract: The invention concerns Gelatin compositions for the use in pharmaceutical, veterinary, food, cosmetic or other products like films for wrapping food, aspics or jellies, preferably for predosed formulations like soft or hard gelatin capsules wherein the gelatin used is of non-bovine and non-pig origin and preferably derived from fish, poultry or plant sources. Especially preferred are film compositions for hard gelatine capsules prepared from fish gelatin.
    Type: Grant
    Filed: June 10, 2004
    Date of Patent: March 7, 2006
    Assignee: Warner-Lambert Company LLC
    Inventors: Robert Scott, Dominque Cadé, Xiongwei He
  • Pyrazole compounds as anti-inflammatory and analgesic agents
    Patent number: 7001917
    Abstract: This invention provides a compound of the formula (I): wherein: R1 represents a hydrogen atom, an alkyl group, etc.; R2 represents a hydrogen atom, a halogen atom, etc.; R3 represents an alkyl group, etc.; R4 represents an aryl group, etc.; A represents an aryl1, etc; B represents an alkylene etc.; X represents NH, etc.; or a pharmaceutically acceptable ester of such compound, and pharmaceutically acceptable salts thereof. These compounds are useful for the treatment of medical conditions mediated by prostaglandin such as pain, fever or inflammation, etc. This invention also provides a pharmaceutical composition comprising the above compound.
    Type: Grant
    Filed: April 9, 2003
    Date of Patent: February 21, 2006
    Assignee: Warner Lambert Company LLC
    Inventors: Misato Hirano, Kazunari Nakao, Seiji Nukui, Tatsuya Yamagishi
  • 5-androsten-3?-ol steroid intermediates and processes for their preparation
    Patent number: 7002028
    Abstract: The present invention provides 5-androsten-3?-ol steroid intermediates and processes for their preparation.
    Type: Grant
    Filed: June 1, 2004
    Date of Patent: February 21, 2006
    Assignee: Warner-Lambert Company
    Inventors: Michael J. White, Peter Guillaume Marie Wuts, Doris Beck
  • Substituted diarylamines as MEK inhibitors
    Patent number: 7001905
    Abstract: Diarylamines, such as 5-amide substituted diarylamines of formula (I) or formula (II) wherein A is hydroxy, C1-6 alkoxy, or NR6OR7; X is OR12, NR13R12, or NR14; inhibitors of MEK and are useful in the treatment of a variety of proliferative disease states, such as conditions related to the hyperactivity of MEK, as well as diseases modulated by the MEK cascade.
    Type: Grant
    Filed: March 12, 2001
    Date of Patent: February 21, 2006
    Assignee: Warner-Lambert Company
    Inventors: Cathlin Biwersi, Haile Tecle, Joseph Scott Warmus
  • Blister card
    Patent number: D515924
    Type: Grant
    Filed: November 1, 2004
    Date of Patent: February 28, 2006
    Assignee: Warner-Lambert Company LLC
    Inventor: Bradford Grant
  • Blister card
    Patent number: D515925
    Type: Grant
    Filed: November 4, 2004
    Date of Patent: February 28, 2006
    Assignee: Warner-Lambert Company LLC
    Inventors: Stephen Don Wahl, Aaron Richard Servier, Robert Peter Arko
  • Blister card
    Patent number: D515926
    Type: Grant
    Filed: November 4, 2004
    Date of Patent: February 28, 2006
    Assignee: Warner-Lambert Company LLC
    Inventors: Stephen Don Wahl, Aaron Richard Servier, Robert Peter Arko
  • Octagon dispenser with bevel
    Patent number: D517406
    Type: Grant
    Filed: January 22, 2004
    Date of Patent: March 21, 2006
    Assignee: Warner-Lambert Company LLC
    Inventors: Peter F. Connolly, Jake Ginder, Steven Ginsberg, Bradford S. Grant, Thomas Zoltner
  • Blister card
    Patent number: D517410
    Type: Grant
    Filed: November 1, 2004
    Date of Patent: March 21, 2006
    Assignee: Warner-Lambert Company LLC
    Inventor: Bradford Grant
  • Dispenser with center opening covers
    Patent number: D518709
    Type: Grant
    Filed: January 22, 2004
    Date of Patent: April 11, 2006
    Assignee: Warner-Lambert Company LLC
    Inventors: Peter F. Connolly, Jake Ginder, Steven Ginsberg, Bradford S. Grant, Thomas Zoltner
  • Blister card
    Patent number: D518721
    Type: Grant
    Filed: November 4, 2004
    Date of Patent: April 11, 2006
    Assignee: Warner-Lambert Company LLC
    Inventors: Stephen Don Wahl, Aaron Richard Servier, Robert Peter Arko