Patents Assigned to William H. Rorer, Inc.
  • Ethynylbenzene compounds and derivatives thereof to treat pain, fever and inflammation
    Patent number: 4166133
    Abstract: A method of treating patients by administering an effective amount of a hydroxy or lower acyloxy substituted ethynylbenzene compound, and the pharmaceutical preparation thereof.
    Type: Grant
    Filed: December 6, 1977
    Date of Patent: August 28, 1979
    Assignee: William H. Rorer, Inc.
    Inventor: Julius Diamond
  • Ethynylbenzene compounds and derivatives thereof
    Patent number: 4157449
    Abstract: Hydroxy, alkoxy and acyloxy ethynylbenzene compounds and their derivatives which are useful for the treatment for the relief of inflammation, pain and fever.
    Type: Grant
    Filed: November 23, 1976
    Date of Patent: June 5, 1979
    Assignee: William H. Rorer, Inc.
    Inventor: Julius Diamond
  • Method of treatment
    Patent number: 4153722
    Abstract: This invention describes a method of treating inflammation in warmblooded animals by topically administering an effective amount of .alpha.-phenyl-N-phenylnitrone and derivatives thereof.
    Type: Grant
    Filed: October 6, 1977
    Date of Patent: May 8, 1979
    Assignee: William H. Rorer, Inc.
    Inventors: Henry F. Campbell, Norman J. Santora, George H. Douglas
  • Method of topically treating inflammation
    Patent number: 4152452
    Abstract: This invention describes a method of treating inflammation in warmblooded animals by topically administering an effective amount of benzylamine and its derivatives.
    Type: Grant
    Filed: October 6, 1977
    Date of Patent: May 1, 1979
    Assignee: William H. Rorer, Inc.
    Inventors: George H. Douglas, Norman J. Santora
  • Synergistic compositions and method of use
    Patent number: 4152430
    Abstract: The present invention relates to a novel synergistic composition and to a method of treating inflammation in warm blooded animals by topically administering to a warm blooded animal in need of such treatment an effective amount of the synergistic combination of a non-steroidal agent having anti-inflammatory activity and at least one adduct of bis-(2-pyridyl-1-oxide) disulfide having the empirical formula:(C.sub.5 H.sub.4 NOS).sub.2 MY.sub.t (I)wherein M represents a member selected from the group consisting of zinc, iron, magnesium, tin, cadmium, zirconium, alkali and alkaline earth metals; Y is the anion of an inorganic acid and t is either 1 or 2.
    Type: Grant
    Filed: September 22, 1977
    Date of Patent: May 1, 1979
    Assignee: William H. Rorer, Inc.
    Inventors: Robert W. Klein, George W. Nuss, Jr.
  • Compositions and method of use
    Patent number: 4152431
    Abstract: The present invention relates to a method of topically treating inflammation in warm blooded animals which comprises administering to a warm blooded animal in need of such treatment an effective amount of bis-(2-pyridyl-1-oxide) disulfide and/or the adducts of bis-(2-pyridyl-1-oxide) disulfide having the empirical formula:(C.sub.5 H.sub.4 NOS).sub.2 MY.sub.t (I)wherein M represents a member selected from the group consisting of zinc, iron, magnesium, tin, cadmium, zirconium, alkali and alkaline earth metals; Y is the anion of an inorganic or organic acid and t is either 1 or 2.
    Type: Grant
    Filed: April 27, 1978
    Date of Patent: May 1, 1979
    Assignee: William H. Rorer, Inc.
    Inventor: Robert W. Klein
  • Amidinoureas
    Patent number: 4150154
    Abstract: This invention describes novel chemical compounds which are 1-amidino-3-phenylureas. The method of preparing these compounds and their pharmaceutical uses is also disclosed.
    Type: Grant
    Filed: March 3, 1975
    Date of Patent: April 17, 1979
    Assignee: William H. Rorer, Inc.
    Inventors: Julius Diamond, Jerome J. Zalipsky
  • Ethynylbenzene compounds and derivatives thereof to treat pain, fever and inflammation
    Patent number: 4150148
    Abstract: A method of treating inflammation, pain or fever in a warm-blooded animal by administering an effective amount of a nitro ethynylbenzene compound, and the pharmaceutical preparation thereof.
    Type: Grant
    Filed: December 6, 1977
    Date of Patent: April 17, 1979
    Assignee: William H. Rorer, Inc.
    Inventor: Julius Diamond
  • Pharmaceutical detergent composition
    Patent number: 4147782
    Abstract: Novel pharmaceutical preparation useful for cleaning the skin of persons affected with acne, chronic oily skin and other skin ailments are disclosed.
    Type: Grant
    Filed: June 24, 1976
    Date of Patent: April 3, 1979
    Assignee: William H. Rorer, Inc.
    Inventors: Robert W. Klein, Mary E. Foxx
  • Amidinourea local anesthetics
    Patent number: 4147804
    Abstract: A method for producing local anesthetic action in a patient by administering amidinoureas.
    Type: Grant
    Filed: May 25, 1977
    Date of Patent: April 3, 1979
    Assignee: William H. Rorer, Inc.
    Inventors: Julius Diamond, George H. Douglas
  • Synergistic compositions and method of use
    Patent number: 4137311
    Abstract: The present invention relates to a novel synergistic composition and to a method of treating inflammation in warm blooded animals by topically administering to a warm blooded animal in need of such treatment an effective amount of the synergistic combination of a corticosteroid and at least one adduct of bis-(2-pyridyl-1-oxide) disulfide having the empirical formula:(C.sub.5 H.sub.4 NOS).sub.2 MY.sub.t (I)wherein M represents a member selected from the group consisting of zinc, iron, magnesium, tin, cadmium, zirconium, alkali and alkaline earth metals; Y is the anion of an inorganic or organic acid and t is either 1 or 2.
    Type: Grant
    Filed: September 22, 1977
    Date of Patent: January 30, 1979
    Assignee: William H. Rorer, Inc.
    Inventors: Robert W. Klein, George W. Nuss, Jr.
  • Medicinal simethicone containing composition and its method of production
    Patent number: 4127650
    Abstract: Simethicone is entrapped in solid, discrete particles of a matrix composition of glycerol and corn syrup solids. A mixture of these particles and a therapeutic antacid overcomes the incompatability of the simethicone and the antacid, due to the shielding action of the matrix composition.
    Type: Grant
    Filed: March 31, 1975
    Date of Patent: November 28, 1978
    Assignee: William H. Rorer, Inc.
    Inventor: John D. Buehler
  • Ethynylbenzene compounds and derivatives thereof
    Patent number: 4120885
    Abstract: Thio substituted ethynylbenzene compounds and their derivatives which are useful for the treatment for the relief of inflammation, pain and fever.
    Type: Grant
    Filed: November 23, 1976
    Date of Patent: October 17, 1978
    Assignee: William H. Rorer, Inc.
    Inventor: Julius Diamond
  • Cyano ethynylbenzene compounds
    Patent number: 4120889
    Abstract: Cyano ethynylbenzene compounds and their derivatives which are useful for the treatment for the relief of inflammation, pain and fever.
    Type: Grant
    Filed: November 23, 1976
    Date of Patent: October 17, 1978
    Assignee: William H. Rorer, Inc.
    Inventor: Julius Diamond
  • Method for lowering the viscosity of certain agents
    Patent number: 4117116
    Abstract: This invention describes a method of lowering the viscosity of aqueous gels of agents used in pharmaceutical preparations and of aqueous suspensions used as pharmaceutical preparations. Particular gels and suspensions and the viscosity lowering ingredients which are most useful are also described.
    Type: Grant
    Filed: March 31, 1975
    Date of Patent: September 26, 1978
    Assignee: William H. Rorer, Inc.
    Inventors: John D. Buehler, Pravinchandra B. Shah, Robert S. Joslin
  • Amidinoureas
    Patent number: 4117165
    Abstract: This invention describes novel chemical compounds which are 1-amidino-3-phenylureas. The method of preparing these compounds and their pharmaceutical uses is also disclosed.
    Type: Grant
    Filed: November 5, 1975
    Date of Patent: September 26, 1978
    Assignee: William H. Rorer, Inc.
    Inventors: Julius Diamond, Jerome J. Zalipsky
  • Amidinoureas
    Patent number: 4115647
    Abstract: A new class of chemical compounds and their process of preparation is described. These compounds have valuable properties as anti-secretory, anti-spasmodic, anti-ulcerogenic and anti-diarrheal agents.
    Type: Grant
    Filed: June 17, 1977
    Date of Patent: September 19, 1978
    Assignee: William H. Rorer, Inc.
    Inventors: George Henry Douglas, William Lyon Studt, Stuart Alan Dodson
  • Treatment of diarrhea with amidinoureas
    Patent number: 4115564
    Abstract: A new class of chemical compounds and their process of preparation is described. These compounds have valuable properties as anti-diarrheal agents.
    Type: Grant
    Filed: November 3, 1976
    Date of Patent: September 19, 1978
    Assignee: William H. Rorer, Inc.
    Inventors: Julius Diamond, George H. Douglas
  • Ethynylbenzene compounds and derivatives thereof
    Patent number: 4105786
    Abstract: A method of treating patients by administering an effective amount of a compound which is a thio ethynylbenzene, and the pharmaceutical preparation thereof.
    Type: Grant
    Filed: January 11, 1977
    Date of Patent: August 8, 1978
    Assignee: William H. Rorer, Inc.
    Inventor: Julius Diamond
  • Ethynylbenzene compounds and derivatives thereof
    Patent number: 4101591
    Abstract: Haloloweralkyl ethynylbenzene compounds and their derivatives which are useful for the treatment for the relief of inflammation, pain and fever.
    Type: Grant
    Filed: November 23, 1976
    Date of Patent: July 18, 1978
    Assignee: William H. Rorer, Inc.
    Inventor: Julius Diamond