Abstract: The disclosure relates to derivatives of imidazoline of the general formula ##SPC1##Or pharmaceutically acceptable acid addition salts thereof wherein R.sup.3 and R.sup.4 which may be the same or different each represent hydrogen or lower alkyl, Ph represents phenyl, halophenyl, lower alkyl phenyl, di(lower alkyl) phenyl or lower alkoxy phenyl, R is hydroxyl, lower alkoxy or halogen, R.sup.1 is phenyl, halophenyl, lower alkyl phenyl, di(lower alkyl)phenyl, lower alkoxy phenyl or napthyl and R.sup.6 is hydrogen or lower alkyl. The compounds have hypoglycemic activity.

Abstract: The invention relates to magnesium halide derivatives of tetrahydroquinolines and related compounds. These are intermediates useful in the preparation of anti-ulcer agents.

Abstract: This invention relates to compounds having the formula: ##SPC1##And the pharmaceutically acceptable acid addition salts thereof, wherein R represents a phenyl or substituted phenyl radical in which said substituent is halogen, lower alkyl, lower alkoxy, nitro or trihalo lower alkyl; A represents a lower alkylene radical; and R.sup.1 and R.sup.2 independently represents hydrogen or lower alkyl; or R.sup.1 and R.sup.2 together with the nitrogen to which they are attached represent a heterocyclic ring selected from pyrrolidino, piperidino or morpholino; which inhibit blood platelet aggregation.

Abstract: The invention provides indolo[2,3-a]quinolizine derivatives which are active as hypotensive and anti-histamine agents. The invention also provides a pharmaceutical composition comprising an indolo[2,3-a]quinolizine derivative together with a pharmaceutical carrier.

Abstract: The invention relates to thioureas which are derivatives of organic nitrogen compounds containing a pyridine ring to which is fused a saturated nitrogen containing ring which carries on its nitrogen atom a thioamide or substituted thioamide group. The compounds are anti-ulcer agents or intermediates therefor.

Abstract: The invention relates to indole derivatives of the formula ##SPC1##And their acid addition salts wherein R is hydrogen or lower alkyl, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are each hydrogen, hydroxyl, lower alkyl, lower alkoxy, trifluoromethyl or halogen and X is a halogen atom. The compounds are useful as antidepressant agents. They can also be cyclised to form anti-depressant 10-aryl-2,3,4,10-tetrahydropyrimido-[1,2-a]indol-10-ols.

Abstract: The invention provides a process for the preparation of alumina gels possessing a high alumina content, namely from 10% to 16%. The gels are useful in the production of antacid preparations. The gels are prepared by admixing a solid aluminium sulphate with an aqueous solution of a carbonate and bicarbonate, thickening the precipitated gel, washing and thickening the gel again.

Abstract: The disclosure describes new 4-aminoquinoline derivatives of general formula ##SPC1##And their acid addition salts, where X is a halogen atom or a trifluoromethyl group, Z is a hydrogen atom or a defined substituent, R is group of the formula--R.sub.3 N--A--NR.sub.1 R.sub.2 (II)--nr.sub.1 n--r.sub.3 (iii a)Or--N N NR.sub.1 R.sub.2 (III b)where A in formula II is a chain of 1 to 5 methylene groups which may be substituted with alkyl, the ring in formula IIIa and IIIb is a piperidine or pyrrolidine ring that may be substituted with alkyl and R.sub.1, R.sub.2 and R.sub.3 represent hydrogen or certain defined substituents. The new 4-aminoquinoline derivatives show anti-hypertensive activity and, in some cases, show one or more of the following activities: anti-malarial activity, anti-inflammatory activity, anti-trichomonal activity and inhibition of blood platelet aggregation.

Abstract: The invention relates to thioureas of formula: ##EQU1## wherein R is phenyl, substituted phenyl or furyl and R.sup.1 is hydrogen or methyl. The compounds are useful as anorexiants.

Abstract: The invention relates to a process for preparing fused ring indole derivatives of formula (I) ##SPC1##wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 are each hydrogen, hydroxyl, lower alkyl, lower alkoxy, haloloweralkyl or halogen, R.sup.5 and R.sup.6 are each hydrogen or lower alkyl and m and n are 0, 1, 2 or 3 and the sum of m + n is 2 or 3, by condensing an indole derivative of formula ##SPC2##With a dihaloalkane of formula ##EQU1## The products have pharmacological activity, particularly antidepressant and hypoglycaemic activity.