Patents Assigned to Xiamen University
  • Publication number: 20250120233
    Abstract: A transfer method for micro flip chips includes forming a first bonding member on a surface of one side of a second electrical connection piece of each of a plurality of micro flip chips facing away from a temporary substrate to which they are adhered. The micro flip chips are transferred onto a drive substrate. The second electrical connection pieces of the micro flip chips are connected to a corresponding one of first electrical connection pieces of the drive substrate via the first bonding members. The micro flip chips are inspected to determine bad point positions of defective chips on the drive substrate. The first bonding member is irradiated at each bad point position by laser and the defective chip is removed. The method ensures stable bonding between the micro flip chips and the drive substrate and prevents the first electrical connection pieces from being damaged by laser irradiation.
    Type: Application
    Filed: April 14, 2023
    Publication date: April 10, 2025
    Applicants: XIAMEN UNIVERSITY, TAN KAH KEE INNOVATION LABORATORY
    Inventors: Xu YANG, Kai HUANG, Jinchai LI, Rong ZHANG
  • Patent number: 12270910
    Abstract: Described herein are systems and methods for training machine learning models to generate three-dimensional (3D) motions based on light detection and ranging (LiDAR) point clouds. In various embodiments, a computing system can encode a machine learning model representing an object in a scene. The computing system can train the machine learning model using a dataset comprising synchronous LiDAR point clouds captured by monocular LiDAR sensors and ground-truth three-dimensional motions obtained from IMU devices. The machine learning model can be configured to generate a three-dimensional motion of the object based on an input of a plurality of point cloud frames captured by a monocular LiDAR sensor.
    Type: Grant
    Filed: August 9, 2022
    Date of Patent: April 8, 2025
    Assignees: Xiamen University, ShanghaiTech University
    Inventors: Cheng Wang, Jialian Li, Lan Xu, Chenglu Wen, Jingyi Yu
  • Patent number: 12232860
    Abstract: A method for fast high-resolution multi-parametric quantitative magnetic resonance imaging comprises: designing a fast high-resolution multiple overlapping-echo imaging pulse sequence; determining sampling parameters of the pulse sequence; constructing a deep neural network for reconstructing high-resolution multi-parametric quantitative magnetic resonance images; generating training samples of the deep neural network; using the training samples to train the deep neural network to obtain trained deep neural networks; scanning a real imaging object using the pulse sequence under the sampling parameters to obtain k-space data of the real imaging object; pre-processing the k-space data of the real imaging object to obtain image domain data of the real imaging object; and inputting the image domain data of the real imaging object into the trained deep neural networks for the reconstructing to obtain the high-resolution multi-parametric quantitative magnetic resonance images of the real imaging object.
    Type: Grant
    Filed: May 31, 2023
    Date of Patent: February 25, 2025
    Assignee: Xiamen University
    Inventors: Shuhui Cai, Wenhua Geng, Qizhi Yang, Congbo Cai, Zhong Chen
  • Patent number: 12230792
    Abstract: A supporter of lithium metal, a material of the supporter of lithium metal is at least one of copper, an alloy of the copper, nickel, or an alloy of the nickel, and a surface of the supporter of lithium metal comprises a lithiophilic surface.
    Type: Grant
    Filed: June 7, 2021
    Date of Patent: February 18, 2025
    Assignee: Xiamen University
    Inventors: BingWei Mao, Yu Gu, Hongyu Xu, Weiwei Wang, Jiawei Yan
  • Patent number: 12209910
    Abstract: The present disclosure provides a radio frequency tagging optical spectrometer, comprising: a dynamic dispersion device, the dynamic dispersion device receiving a beam comprising more than two wavelength components and being driven by driving radio frequency signals, and the dynamic dispersion device encoding the intensity of each wavelength component into the amplitude of a different beat radio frequency signal based on different driving radio frequency signals, wherein the beat frequency of the different beat radio frequency signal is equal to the frequency of the corresponding driving radio frequency signal; a single-channel photodetector for detecting the sum of beat radio frequency signals formed by adding all the beat radio frequency signals; and a processing unit for performing Fourier transform on the sum of the beat radio frequency signals to obtain a spectrum or an associated radio frequency spectrum by which the optical spectrum is obtained.
    Type: Grant
    Filed: January 2, 2023
    Date of Patent: January 28, 2025
    Assignee: Xiamen University
    Inventor: Quan Liu
  • Publication number: 20250006858
    Abstract: The present application provides a display panel and a manufacturing method thereof, the manufacturing method comprises: providing a first substrate, wherein a side of the first substrate is provided with a plurality of Micro-LED chips that are spaced apart from each other; providing a second substrate, wherein a surface on a side of the second substrate has a plurality of conductive layer parts; forming an isolation layer on the second substrate, wherein the isolation layer has a plurality of opening groups, each of the opening groups comprises a first opening and a second opening to expose a surface of one of the conductive layer parts, wherein a width of the first opening is greater than that of a P-type electrode, and a width of the second opening is greater than that of a N-type electrode; forming a first bonding layer in the first opening and forming a second bonding layer in the second opening; while supporting the chip body by the isolation layer, bonding the P-type electrode with the first bonding la
    Type: Application
    Filed: April 19, 2023
    Publication date: January 2, 2025
    Applicants: XIAMEN UNIVERSITY, TAN KAH KEE INNOVATION LABORATORY
    Inventors: Kai HUANG, Xiaowei ZHANG, Xu YANG, Jinchai LI, Rong ZHANG
  • Patent number: 12169181
    Abstract: A transmission imaging detection device (10) is used to collect projection diagrams of measured objects (200) on a conveyor belt (100), comprising X-ray projection imaging devices and laser occlusion sensing devices, the measured objects (200) shifts across the X-ray projection imaging devices and laser occlusion sensing devices on the said conveyor belt (100), and the laser occlusion sensing devices determines whether the measured objects (200) enter the detection segments, the X-ray projection imaging devices collect projection data of the measured objects (200). The transmission imaging detection device (10) combines the translation motion of the measured objects (200) to complete the data acquisition required for real-time CT slice imaging. The computerized tomography system using the above-mentioned transmission imaging detection device (10) ultimately realizes the real-time reconstruction, storage and display of CT slices by bus data transmission and cluster operation.
    Type: Grant
    Filed: September 19, 2019
    Date of Patent: December 17, 2024
    Assignee: XIAMEN UNIVERSITY
    Inventor: Zheng Fang
  • Publication number: 20240409621
    Abstract: The present invention relates to the field of immunology and molecular virology, and in particular relates to the field of the prevention and treatment of RSV. Specifically, provided are a monoclonal antibody capable of specifically binding to a new epitope between an Ø epitope and a V epitope on a pre-F protein or a new epitope between an II epitope and a V epitope, and the use thereof in the detection, prevention and/or treatment of RSV infection and/or diseases caused by the infections.
    Type: Application
    Filed: August 15, 2022
    Publication date: December 12, 2024
    Applicant: XIAMEN UNIVERSITY
    Inventors: Zizheng ZHENG, Yongpeng SUN, Siyu LEI, Hongsheng QIANG, Li CHEN, Ningshao XIA
  • Publication number: 20240408594
    Abstract: The present disclosure relates to a microfluidic chip and a microfluidic chip detection system. The microfluidic chip including: a storage member provided with a groove therein, at least two storage chambers being disposed around the groove; a base disposed at one end of the storage member away from the groove, a reaction chamber being disposed on the base; and a valve disposed in the groove, the valve being configured to operatively communicate any one of the at least two storage chambers with the reaction chamber. The present disclosure can lead the solution in any storage chamber to the reaction chamber or lead the solution in the reaction chamber to any storage chamber by operating the valve, so that the solution transfer is realized, the structure is simple and compact, the length of the flow channels can be greatly shortened, and the detection efficiency is improved.
    Type: Application
    Filed: November 11, 2022
    Publication date: December 12, 2024
    Applicants: XIAMEN UNIVERSITY, XIAMEN INNODX BIOTECH CO., LTD
    Inventors: Dongxu ZHANG, Runxin GAO, Shaolei HUANG, Yulin HUANG, Guoqiang LIU, Jiayu YANG, Juntian ZENG, Liuwei SONG, Shengxiang GE, Jun ZHANG, Ningshao XIA
  • Patent number: 12146042
    Abstract: The present disclosure discloses a method for preparing dual-sensitive cellulose-based aerogel. The DAC (Dialdehyde cellulose), the DAC/PDMAEMA (poly-2-(dimethylamino)ethyl methacrylate) copolymer, the DAC/PDMAEMA/PEI (Polyethylenimine) copolymer are serially prepared, was freeze-dried to obtain a product. The product is the dual-sensitive cellulose-based aerogel, a cumulative adsorption capacity of the dual-sensitive cellulose-based aerogel is 250 mg/g, and a cumulative release amount of the dual-sensitive cellulose-based aerogel in 0.05 mol/L NaH2PO4 (pH=3-8), 0.2% NaCl (pH<3), or NaOH (pH>8) is 63-90%.
    Type: Grant
    Filed: January 12, 2021
    Date of Patent: November 19, 2024
    Assignee: Xiamen University
    Inventors: Xianhai Zeng, Guihua Yan, Yong Sun, Xing Tang, Lu Lin, Tingzhou Lei
  • Patent number: 12115245
    Abstract: An anterior chamber perfusate for intraocular surgery and its use. The anterior chamber perfusate not only balances intraocular pressure, but also contains a certain amount of L-alanyl-L-glutamine (Ala-Gln).
    Type: Grant
    Filed: August 30, 2021
    Date of Patent: October 15, 2024
    Assignee: Xiamen University
    Inventors: Cheng Li, Mengyi Jin, Ying Hong, Zuguo Liu
  • Publication number: 20240328946
    Abstract: The present disclosure provides a fluorescence analysis method for lithium ion determination using free-base phthalocyanine (FBPc) as a molecular probe, and relates to the technical field of fluorescent probes. The method includes the following steps: adding an alkaline organic medium separately into a plurality of reaction vessels, and adding a phthalocyanine organic solution having a same volume as that of the alkaline organic medium; adding lithium ion organic solutions with increasing concentrations in sequence; diluting an obtained reaction system, allowing to stand to conduct a reaction, scanning a fluorescence spectrum of the reaction system, and determining a relative fluorescence intensity at a fluorescence peak. A determination principle is that in organic media, especially an alkaline organic medium, lithium ions can react with the FBPc to emit strong red fluorescence, and generation of the fluorescence has the remarkable characteristics of ultra-sensitivity and high specificity.
    Type: Application
    Filed: October 13, 2022
    Publication date: October 3, 2024
    Applicant: Xiamen University
    Inventors: Donghui LI, Yan ZHANG, Ping HUANG, Yabin DENG
  • Patent number: 12102086
    Abstract: An antimicrobial peptide Spampcin56-86from Scylla paramamosain is provided. A molecular formula of the antimicrobial peptide Spampcin56-86 is C154H256N54O33S3, and an amino acid sequence of the antimicrobial peptide Spampcin56-86 is shown in SEQ ID NO: 01.
    Type: Grant
    Filed: August 24, 2023
    Date of Patent: October 1, 2024
    Assignee: XIAMEN UNIVERSITY
    Inventors: Kejian Wang, Manyu Jiang, Fangyi Chen
  • Patent number: 12097251
    Abstract: Provided are a mutated HPV51 L1 protein or a variant thereof, a coding sequence thereof, a preparation method therefor, and a virus-like particle containing same, wherein the protein or the variant and the virus-like particle thereof are capable of inducing neutralizing antibodies against at least two types of HPV (for example, HPV51 and HPV69, or HPV51, HPV69 and HPV26). Also provided is the use of the above-mentioned protein and the virus-like particle for preparing a pharmaceutical composition or a vaccine, wherein the pharmaceutical composition or the vaccine can be used to prevent infections of the at least two types of HPV and diseases caused by the infections, such as cervical cancer and condyloma acuminatum.
    Type: Grant
    Filed: September 26, 2019
    Date of Patent: September 24, 2024
    Assignees: XIAMEN UNIVERSITY, XIAMEN INNOVAX BIOTECH CO., LTD.
    Inventors: Shaowei Li, Daning Wang, Jie Chen, Ying Gu, Jun Zhang, Ningshao Xia
  • Patent number: 12077679
    Abstract: Disclosed are an intumescent fire-retardant coating with ultra-high corrosion resistance and a preparation method thereof. The fire-retardant coating is composed by water, wetting and dispersing agent, defoaming agent, composite carbon-forming catalyst, composite blowing agent, pentaerythritol, titanium dioxide, Mg(OH)2, mica powder, kaolin, anti-rust pigment, aluminum tripolyphosphate, VAE emulsion, freeze-thaw agent, film-forming aid, and thickener. On the basis of the existing fire-retardant coatings, the present disclosure adds a series of anti-corrosion, heat insulation fillers and salt spray resistance additives to achieve a certain salt spray resistance effect. The fire-retardant coating of the present disclosure has both fire-retardant and anticorrosive functions, does not contain organic solvents, is low in price, has high construction tolerance, and has broad application prospects in the field of intumescent fire-retardant coatings.
    Type: Grant
    Filed: November 24, 2021
    Date of Patent: September 3, 2024
    Assignees: FUJIAN SOUTH PEAK FIRE PREVENTION TECHNOLOGY CO., LTD., XIAMEN UNIVERSITY
    Inventors: Jianghai Fang, Lizong Dai, Qingliang Liu, Yansong Liu, Huanhuan Xu, Chun'e Guo
  • Patent number: 12033246
    Abstract: A method and system for simultaneous quantitative multiparametric MRI are provided in the disclosure. The method includes: designing a magnetic resonance imaging (MRI) sequence which includes a signal excitation part, a shift gradient part, and a data acquisition part; generating training samples for a deep neural network according to the MRI sequence; training the deep neural network by using the training samples, to obtain a trained deep neural network; and reconstructing multiple magnetic-resonance parametric maps by using the trained deep neural network and k-space data acquired by the MRI sequence. The disclosure can implement quantitative multiparametric MRI, and can correct image distortions caused by magnetic field inhomogeneity.
    Type: Grant
    Filed: November 5, 2020
    Date of Patent: July 9, 2024
    Assignee: XIAMEN UNIVERSITY
    Inventors: Shuhui Cai, Jian Wu, Congbo Cai
  • Patent number: 12031073
    Abstract: A nitride near-infrared fluorescent material has a general molecular formula of the nitride near-infrared fluorescent material is (Ca1?x?y?zSrxBayEuz)3[LiaMgbAlcSid]N6. In the general molecular formula, 0?x<1; 0?y?0.3; 0<z?0.02; 3.4?a?4; 0?b?0.2; 0?c?0.4; 1.8?d?2; a+2b+3c+4d=12. The material can be adjusted and controlled to achieve a maximum emission peak wavelength of 830 nm, a maximum half-peak width of 4283 cm?1, and a quantum yield of 77%.
    Type: Grant
    Filed: June 8, 2020
    Date of Patent: July 9, 2024
    Assignee: XIAMEN UNIVERSITY
    Inventors: Rongjun Xie, Shuxing Li
  • Patent number: 11987674
    Abstract: A method for preparing anisotropic cellulose-based hydrogel is provided. The method comprises ammoniating the dialdehyde cellulose obtained by oxidizing cellulose using sodium periodate to obtain ammoniated cellulose derivatives; performing Schiff reaction using the ammoniated cellulose derivatives and dopamine to obtain cellulose-based nanosheets; depositing Fe3O4 nanoparticles on a surface of the cellulose-based nanosheets by a deposition method to obtain magnetic cellulose-based nanosheets; and forming the anisotropic cellulose-based hydrogel using the magnetic cellulose-based nanosheets by a polymerization method.
    Type: Grant
    Filed: August 22, 2023
    Date of Patent: May 21, 2024
    Assignee: XIAMEN UNIVERSITY
    Inventors: Xianhai Zeng, Guihua Yan, Lu Lin, Yong Sun, Xing Tang
  • Patent number: 11982002
    Abstract: An anticorrosion treatment method for a copper-containing material comprises: carrying out a sealed and pressurized reaction on a copper-containing material and a stabilizer in presence of a polar solvent and any assistant, the stabilizer being a compound capable of providing formates, so that the formates are adsorbed on the surface of the copper-containing material. In the method, formates are modified on the surface of the copper-containing material, accordingly, the oxidation resistance capability and the stability of the copper-containing material can be significantly improved while the electrical conductivity of the copper-containing material is not reduced, and the corrosion resistance of the copper-containing material and especially, the salt and alkali corrosion resistance of the copper-containing material are significantly improved.
    Type: Grant
    Filed: August 17, 2018
    Date of Patent: May 14, 2024
    Assignee: XIAMEN UNIVERSITY
    Inventors: Nanfeng Zheng, Jian Peng, Shuqiang Hao, Binghui Wu, Xiaoliang Fang
  • Patent number: 11952368
    Abstract: Provided are a fibroblast activation protein inhibitor (FAPI) dimer compound, an FAPI dimer-based positron emission tomography (PET) imaging agent for tumor diagnosis, and a preparation method and use thereof. An amphiphilic polyethylene glycol (PEG) chain and a dimerized structure of FAPI in the FAPI dimer compound with a structure shown in formula I can improve the in vivo kinetic properties of the compound and prolong a residence time of the compound in a tumor, thereby improving the uptake and imaging effects in the tumor. The accurate tumor diagnosis can be achieved by labeling the FAPI dimer compound with a diagnostic nuclide (68Ga), which has promising application prospects in PET imaging for diagnosis and in the preparation of a therapeutic nuclide (such as 177Lu or 90Y)-labeled drug for treating a FAP-?-expressing tumor.
    Type: Grant
    Filed: September 29, 2022
    Date of Patent: April 9, 2024
    Assignee: Xiamen University
    Inventors: Haojun Chen, Liang Zhao, Qin Lin, Kaili Fu, Yizhen Pang, Zhide Guo, Jianyang Fang, Long Sun, Hua Wu