Abstract: The invention concerns novel, pharmaceutically useful, amide derivatives of certain benzoheterocyclylalkanoic acids (and related tetrazoles and acylsulphonamides) of the formula I and salts thereof, wherein the radicals R.sup.1, R.sup.2, L, X, Y, Z, A.sup.1, Q, A.sup.2 and M have the meanings set out in the specification. The invention also includes pharmaceutical compositions incorporating a formula I compound or a salt thereof, a process for the manufacture of the said compound, together with intermediates for use in the latter process.

Abstract: The invention concerns quinazoline derivatives of the formula I ##STR1## wherein m is 1, 2 or 3 and each R.sup.1 includes hydroxy, amino, ureido, hydroxyamino, trifluoromethoxy, (1-4C)alkyl, (1-4C)alkoxy and (1-3C)alkylenedioxy; and Q is a 9- or 10-membered bicyclic heterocyclic moiety containing one or two nitrogen heteroatoms and optionally containing a further heteroatom selected from nitrogen, oxygen and sulphur, or Q is a 9- or 10-membered bicyclic aryl moiety which heterocyclic or aryl moiety may optionally bear one or two substituents selected from halogeno, hydroxy, oxo, amino, nitro, carbamoyl, (1-4C)alkyl, (1-4C)alkoxy, (1-4C)alkylamino, di-[(1-4C)alkyl]amino and (2-4C)alkanoylamino; or a pharmaceutically-acceptable salt thereof; processes for their preparation; pharmaceutical compositions containing them; and the use of the receptor tyrosine kinase inhibitory properties of the compounds in the treatment of cancer.

Abstract: Disclosed are solid, phytoactive, N-phosphonomethyl-N-carboxymethyl compositions. Also disclosed are processes for the preparation of such compositions by(a) forming an initial mixture comprising a phytoactive N-phosphonomethyl-N-carboxymethyl compound, a solvent and a molten surfactant, the surfactant being solid at ambient temperatures;(b) removing solvent from the initial mixture to form a final mixture at a temperature above the melting point of the surfactant;(c) cooling the final mixture to a temperature below the melting point of the surfactant to form a N-phosphonomethyl-N-carboxymethyl composition which is solid at ambient temperatures; and(d) processing said composition into particulate form, such as pellets, flakes, granules, or powders.

Abstract: A compound of formula ##STR1## in which X is hydrogen or a group of formula --SO.sub.2 NH.sub.2 is reduced to the trans (4S,6S) form of the corresponding alcohol by an enzyme reduction system.

Abstract: A supported or cast film of a polyhydroxyalkanoate polymer, such as a polyhydroxybutyrate/valerate polymer, can be prepared by applying a layer of molten polymer to a cool (typically 4.degree. to 20.degree. C.) surface not substantially above the glass transition temperature of the polymer, so as to form a solid, glassy film with a high density of nucleation sites; subsequently the temperature of the film so formed is raised, for example to 40.degree. C. or more, towards the optimum temperature for growth of the polymer's spherulites effectively separating the film formation/nucleation step from the crystallisation step (growth of spherulites around the nucleation sites). Smaller crystallites are formed, and the film has improved barrier properties.

Abstract: The invention concerns chemical compounds of formula IR.sup.1 --CON(R.sup.2)--CON(R.sup.3)--X.sup.1 --Q--X.sup.2 --GIand pharmaceutically acceptable metabolically labile esters or amides thereof, and pharmaceutically acceptable salts thereof, in which R.sup.1, R.sup.2, R.sup.3, X.sup.1, Q, X.sup.2 and G have the meanings given in the specification. The invention concerns processes for the preparation of the chemical compounds of formula I, pharmaceutical compositions containing them and their use as inhibitors of the binding of fibrinogen to glycoprotein IIb/IIIa.

Abstract: The present invention concerns novel carboxamide derivatives of formula I, ##STR1## wherein R.sup.1, R.sup.2, J, m, and M have any of the values defined in the specification, which antagonize the pharmacological actions of one of the endogenous neuropeptide tachykinins at the neurokinin 2 (NK2) receptor, making them useful whenever such antagonism is desired, such as in the treatment of asthma and related conditions. The invention also provides pharmaceutical compositions containing the novel carboxamide derivatives for use in such treatment, methods for their use, and processes and intermediates for the manufacture of the novel carboxamide derivatives.

Abstract: This invention relates to maize plants and a method of producing same, which are resistant to Gray Leaf Spot which will hereinafter simply be referred to as GLS. More particularly this invention relates to the introgression in maize of identifiable genetic material capable of causing the plant to be resistant to GLS. Additionally, the present invention relates to the introgression of desired genetic material from one or more parent plants into progeny plants with precision and accuracy.

Abstract: Three similar gene sequences are provided, the sequences being shown in the drawings, which are recovered from male flower parts of maize, specifically anther tissue. When one or more of these sequences are included in a gene construct, expression of an encoded protein is restricted to male parts of the plant. The sequences have utility in any application where expression in male flower parts is indicated, a specific application is in the control of expression of a disrupter protein which imparts male sterility when incorporated in a plant genome.

Abstract: The present invention relates to carbapenems and provides a compound of the formula (I) ##STR1## wherein: R.sup.1 is 1-hydroxyethyl, 1-fluoroethyl or hydroxyethyl;R.sup.2 is hydrogen or C.sub.1-4 alkyl;R.sup.3 is hydrogen or C.sub.1-4 alkyl;P is of the formula (IA), (IB) or (IC) ##STR2## and in the formula (IB) the naphthyl group may be bonded to the nitrogen of the linking carbamoyl group at either ring; Z is carboxy, sulfonic acid, sulfinic acid, C.sub.1-4 alkanamidosulfonyl (--SO.sub.2 NHCOC.sub.1-3 alkyl), benzamidosulfonyl, C.sub.1-4 alkylsulfonylcarbamoyl (--CONHSO.sub.2 C.sub.1-4 alkyl), phenylsulfonylcarbamoyl, C.sub.1-4 alkoxy carbamoyl, hydroxycarbamoyl, sulfoamino, N--C.sub.1-4 alkanesulfonamido, cyanocarbamoyl, cyanosulfamoyl, tetrazol-5-yl, 3-hydroxyisoxazol-4-yl and 3-hydroxyisoxazol-5-yl;and P is optionally further substituted provided that when P is of the formula (IA) or (IC), Z is not carboxy;or a pharmaceutically acceptable salt or in vivo hydrolysable ester thereof.

Abstract: Broadly this invention provides inbred corn line ZS1284. The methods for producing a corn plant by crossing the inbred line ZS1284 are encompassed by the invention. Additionally, the invention relates to the various parts of inbred ZS1284 including culturable cells. This invention relates to hybrid corn seeds and plants produced by crossing the inbred line ZS1284 with at least one other corn line.

Abstract: An inbred corn line designated ZS0114, including plants of ZS0114 and pollen and seed of such plants. Also, a method of producing a corn plant by crossing ZS0114 either with itself or with another corn line and the first generation plants and seeds produced by such crosses.

Abstract: The invention concerns tricyclic derivatives of the formula I ##STR1## wherein R.sup.1 and R.sup.2 together form an optionally substituted group of the formula --N.dbd.CH--NH--, --N.dbd.CH--O--, --N.dbd.CH--S--, --N.dbd.N--NH--, --NH--N.dbd.CH--, --NH--CH.dbd.CH--. --NH--CO--NH--, --NH--CO--O--, --NH--CO--S--, --NH--NH--CO--, --N.dbd.CH--CH.dbd.N--, --N.dbd.N--CH.dbd.CH--, --N.dbd.CH--N.dbd.CH--, --N.dbd.CH--CH.dbd.N--, --NH--CO--CH.dbd.CH-- or --N.dbd.CH--CO--NH--; m is 1, 2 or 3 and R.sup.3 includes hydrogen, halogeno and (1-4C)alkyl; or a pharmaceutically-acceptable salt thereof;processes for their preparation; pharmaceutical compositions containing them; and the use of the receptor tyrosine kinase inhibitory properties of the compounds. in the treatment of cancer.

Abstract: An inbred corn line designated ZS0223, including plants of ZS0223 and pollen and seed of such plants. Also, a method of producing a corn plant by crossing ZS0223 either with itself or with another corn line and the first generation plants and seeds produced by such crosses.

Abstract: Compounds of formula I ##STR1## wherein G, J, L, M, m and D have any of the meanings given in the specification, their N-oxides, and their pharmaceutically acceptable salts are nonpeptide antagonists of neurokinin A and useful for the treatment of asthma, etc. Also disclosed are pharmaceutical compositions, processes for preparing the compounds of formula I and intermediates.

Abstract: Herbicidal compounds have the formula ##STR1## in which: R.sub.1 is hydrogen, halogen; C.sub.1 -C.sub.4 alkyl; C.sub.1 -C.sub.4 haloalkyl; C.sub.1 -C.sub.4 alkoxy; C.sub.1 -C.sub.4 haloalkoxy; C.sub.2 -C.sub.8 alkoxyalkyl; nitro; cyano; thiocyano; or R.sub.7 S(O).sub.m - where m is 0, 1 or 2 and R.sub.7 is C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 haloalkyl;R.sub.2 and R.sub.3 are independently hydrogen; halogen; C.sub.1 -C.sub.4 alkyl; C.sub.1 -C.sub.4 alkoxy; C.sub.1 -C.sub.4 haloalkyl; C.sub.1 -C.sub.4 haloalkoxy; C.sub.2 -C.sub.8 alkoxyalkyl; nitro; R.sub.8 S(O).sub.2 O- or R.sub.8 S(O).sub.n - where n is 0, 1 or 2 and R.sub.8 is C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 cyanoalkyl, phenyl or benzyl; NR.sub.9 R.sub.10 where R.sub.9 and R.sub.10 are independently hydrogen or C.sub.1 -C.sub.4 alkyl; R.sub.11 CO- where R.sub.11 is C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkoxy, SO.sub.2 NR.sub.12 R.sub.13 where R.sub.12 and R.sub.13 are independently hydrogen, C.sub.1 -C.sub.

Abstract: A process for the preparation of 2-(substituted)-4-sulfobenzoic acid by oxidation of 2-(substituted)-4-toluenesulfonic acid.

Abstract: A herbicidal composition comprising herbicidally effective amounts of a diphenyl ether of the formula ##STR1## at least one nitrogen containing fertilizer that is present in an amount that increases the herbicidal activity of said diphenyl ether; andone or more adjuvants.

Abstract: A process for the cultivation in continuous culture of a filamentous microorganism in a culture medium to which are supplied sources of carbon and other appropriate nutrients. The carbon or another nutrient source is supplied in an amount limiting to the growth of the culture and constitutes a limiting nutrient thereto. The development of an unwanted variant of the filamentous microorganism is restricted or delayed by supplying a first nutrient source to the culture as a limiting nutrient, and thus changing the nutrient supply to the culture in a manner such that a second nutrient source replaces the first nutrient source as the limiting nutrient.

Abstract: An inbred corn line designated ZS0510, including plants of ZS0510 and pollen and seed of such plants. Also, a method of producing a corn plant by crossing ZS0510 either with itself or with another corn line and the first generation plants and seeds produced by such crosses.