Abstract: Compounds of formula I ##STR1## wherein Q.sup.1, m and M have any of the meanings given in the specification, their N-oxides, and their pharmaceutically acceptable salts are nonpeptide antagonists of neurokinin A and useful for the treatment of asthma, etc. Also disclosed are pharmaceutical compositions, processes for preparing the compounds of formula I and intermediates.

Abstract: Process for the free-radical polymerisation of olefinically unsaturated monomer(s) using a free-radical initiator, wherein said polymerisation is performed in the presence of a compound for effecting molecular weight control, said molecular weight control compound being selected from Cobalt II chelates of the following formulae I, II and III: ##STR1## wherein: x and y are independently 2 to 5;each R.sup.1, R.sup.2, R.sup.3 and R.sup.4 is independently selected from H, C1-C12 alkyl, optionally substituted aryl, OR.sup.5 where R.sup.5 is C1 to C12 alkyl or optionally substituted aryl, CO.sub.2 R.sup.5, SO.sub.3 H, C(.dbd.O)R.sup.5, CO.sub.2 H, NO.sub.2, OH, NR.sup.5.sub.2, NH.sub.2, NHR.sup.5, SR.sup.5, SH, CN, SO.sub.3 R.sup.5, halogen, 2-furyl and 3-furyl;each X is independently selected from (CR.sup.6.sub.2).sub.n, (CR.sup.6.sub.2 O).sub.n, optionally substituted o-phenylene, and optionally substituted 1,8-naphthylene, where each R.sup.

Abstract: A polymer composition comprising a crystallisable polymer stabilised in an amorphous or incompletely crystalline state by forming particles at least partly coated with a surfactant or phospholipid and to processes for preparing a such a polymer composition.

Abstract: Biocidal proteins capable of isolation from seeds have been characterized. The proteins have an amino acid sequence containing the common cysteine/glycine domain of Chitin-binding Plant Proteins but show substantially better activity against pathogenic fungi, a higher ratio of basic amino acids to acidic amino acids, and/or antifungal activity which results in increased hyphal branching. Antimicrobial proteins isolated from Amaranthus, Capsicum, Briza and related species are provided. The proteins show a wide range of antifungal activity and are active against Gram-positive bacteria. DNA encoding the proteins may be isolated and incorporated into vectors. Plants may be transformed with this DNA. The proteins find agricultural or pharmaceutical application as antifungal or antibacterial agents. Transgenic plants expressing the protein will show increased disease resistance.

Abstract: The present invention relates to a method for detecting the presence or absence of one or more variant nucleotide sequences. The method comprises (i) contacting a nucleic acid sample with a diagnostic primer which is substantially complementary to a diagnostic portion of a target base sequence, whereby extension of the diagnostic primer on a target template under appropriate conditions is only achieved where a terminal nucleotide of the diagnostic primer is complementary to either a suspected variant nucleotide or a corresponding normal nucleotide of the target base sequence, and (ii) detecting the presence or absence of an extension product. Kits for performing diagnostic tests are also disclosed.

Abstract: Compounds having a 5 membered, nitrogen containing ring with a thione group adjacent to a nitrogen atom substituted with an OR group have antimicrobial properties. Metal complexes or salts of these compounds also have antimicrobial properties. The compounds, or the metal complexes or salts thereof, can be used as a cutting fluid preservative, a wood preservative, in cooling water applications or as an antimicrobial agent in a paint. Some of the compounds are new. The metal complexes or salts are new.

Abstract: Herbicidal 3-substituted pyridine compounds and derivatives thereof of the formula: ##STR1## wherein Ar is a substituted or unsubstituted 5- or 6-membered heteroaryl group having 1, 2 or 3 ring nitrogen atoms with the remainder of the ring atoms being carbon; a substituted or unsubstituted 5-membered heteroaryl group having a ring heteroatom of oxygen or sulfur with the remainder of the ring atoms being carbon; or a substituted or unsubstituted 5-membered heteroaryl group having one ring nitrogen atom and either an oxygen or sulfur ring heteroatom with the remainder of the ring atoms being carbon. Herbicidal compositions containing such 3-substituted pyridine compounds and derivatives thereof and methods of controlling undesirable vegetation employing these compounds and derivatives are also disclosed. The compounds in which XR is hydroxyl are also useful as intermediates for producing the disclosed 3-substituted pyridine derivatives.

Abstract: The invention relates to N-(.beta.-branched alkyl)-1,2-benzisothiazolin-3-ones having two or more carbon atoms in the alkyl side chain such as N-(2-ethylhexyl)-1,2-benzisothiazolin-3-one, which are suitable as paint film fungicides.

Abstract: Powder coating composition which comprises a hybrid polymer system in granular form of a polymer A formable from monomer(s) by aqueous suspension polymerisation and a polymer B, different to A, which polymer system has been obtained using a process which comprises dissolving polymer B in monomeric material to be used in the formation of polymer A, polymerising the monomer(s) to form polymer A using an aqueous suspension polymerisation process, and removing the aqueous phase to form a hybrid of the polymers A and B in granular form, and wherein polymer A and polymer B bear functional groups for imparting curability to the hybrid polymer system, and wherein further the hybrid polymer system has a number average molecular weight within the range of from 1500 to 15,000.

Abstract: The invention concerns novel cross-linked poly(N,N-dialkylallyl)ammonium polymer materials containing quaternary propylammonium structural units which are effective in lowering elevated plasma levels of low density lipoproteins and lipoid components thereof, such as cholesterol, and which are of value in the treatment of conditions in which such elevated plasma levels are associated, for example, various vascular diseases. The invention also provides methods for the manufacture of the polymer materials and various intermediates for use in such manufacture.

Abstract: Compounds of formula I ##STR1## wherein Q.sup.1, Q.sup.2, Q.sup.3, and Q.sup.4 have any of the meanings given in the specification, their N-oxides, and their pharmaceutically acceptable salts are nonpeptide antagonists of neurokinin A and useful for the treatment of asthma, etc. Also disclosed are pharmaceutical compositions, processes for preparing the compounds of formula I and intermediates.

Abstract: The chemically-inducible 27 kD subunit of the enzyme glutathione-S-transferase, isoform II (GST-II-27) and sequences encoding it are provided. In particular, a genomic DNA sequence encoding the gene promoter for the GST-II-27 subunit is provided. When linked to an exogenous gene and introduced into a plant by transformation, the GST-II-27 promoter provides a means for the external regulation of expression of that exogenous gene. Transformation with DNA encoding glutathione-S-transferase polypeptides produces herbicide resistance transgenic plants.

Abstract: Prodrugs, of generic formula I, are disclosed for use in antibody directed enzyme prodrug therapy (ADEPT).

Abstract: An inbred corn line designated ZS1513, including plants of ZS1513 and pollen and seed of such plants. Also, a method of producing a corn plant by crossing ZS1513 either with itself or with another corn line and the first generation plants and seeds produced by such crosses.

Abstract: An inbred corn line designated ZS0853, including plants of ZS0853 and pollen and seed of such plants. Also, a method of producing a corn plant by crossing ZS0853 either with itself or with another corn line and the first generation plants and seeds produced by such crosses.

Abstract: 4-substituted pyridyl-3-carbinols of the formula ##STR1## wherein R is hydrogen, or an acyl, alkyl or carbamyl group exhibit desirable preemergent and postemergent herbicidal activity. Also disclosed are herbicidal compositions comprising such compounds and methods of controlling undesirable vegetation employing such compounds. The compounds wherein AR is hydroxyl serve as useful intermediates for the production of the alpha-benzyl substituted compounds as well as exhibiting herbicidal activity.

Abstract: Broadly this invention provides inbred corn line ZS1791. The methods for producing a corn plant by crossing the inbred line ZS1791 are encompassed by the invention. Additionally, the invention relates to the various parts of inbred ZS1791 including culturable cells. This invention relates to hybrid corn seeds and plants produced by crossing the inbred line ZS1791 with at least one other corn line.

Abstract: An inbred corn line designated ZS0560, including plants of ZS0560 and pollen and seed of such plants. Also, a method of producing a corn plant by crossing ZS0560 either with itself or with another corn line and the first generation plants and seeds produced by such crosses.

Abstract: A compound of the formula: ##STR1## useful as an intermediate in the preparation of fungicides.

Abstract: A composition comprises (a) halogenated aromatic 1,2- or 1,3- dinitrile, (b) a substituted urea and (c) a halogen-containing aromatic alkyl sulphoxide or sulphone. The composition may include other materials for example inorganic diluents such as silica, alumina, titanium, dioxide, zinc oxide, etc. and may also include other anti-microbial agents such are anti-bacterial agents. The composition has anti-microbial properties, particularly anti-fungal and anti-algal properties. The composition can be incorporated into materials such as paint or plastics to provide anti-microbial properties.