Patents Assigned to Zoetis Services LLC
  • Spirocyclic isoxazoline parasiticidal combinations
    Patent number: 9226928
    Abstract: The present invention relates to a novel antiparasitic composition comprising an effective amount of a) a Formula (1) compound, wherein R1a, R1b, R1c, R2, R3, R4, and n are as defined herein, stereoisomer thereof, or a pharmaceutical or veterinary acceptable salt thereof, b) a macrocyclic lactone or derivative thereof and c) optionally, at least one additional veterinary agent, and further comprising at least one veterinary or pharmaceutical acceptable carrier; and a method of treating an animal with a parasitic infection, by administering an effective amount of said composition to the animal in need thereof.
    Type: Grant
    Filed: September 4, 2013
    Date of Patent: January 5, 2016
    Assignee: Zoetis Services LLC
    Inventors: Nathan Anthony Logan Chubb, Kevin Evans, Tom L. McTier, Patrick F. M. Meeus
  • Spirocyclic derivatives as antiparasitic agents
    Patent number: 9221835
    Abstract: The invention recites spirocyclic derivatives of Formula (V.1) or (V.2), stereoisomers thereof, veterinary acceptable salts thereof, compositions thereof, processes for making, and their use as a parasiticide for an animal. The variables A, B, V, Z, Y, W1, W2, W3, R1a, R1b, R1c, R2, R3, R4, n, and “ - - - ” are as described herein.
    Type: Grant
    Filed: September 4, 2013
    Date of Patent: December 29, 2015
    Assignee: Zoetis Services LLC
    Inventors: Susan M. K. Sheehan, Valerie A. Vaillancourt
  • Bluetongue virus vaccine and immunogenic compositions, methods of use and methods of producing same
    Patent number: 9205145
    Abstract: Provided are immunogenic and vaccine compositions and methods for their preparation and use, which compositions are effective in protecting against, minimizing the severity of, preventing, and/or ameliorating infection of ruminants with Bluetongue virus. Administration to an animal of at least one dose of an adjuvanted and twice inactivated Bluetongue virus composition as disclosed herein is effective in providing immunity to the animal and protection from infection with Bluetongue virus, thereby reducing the severity of and/or preventing disease caused by one or more strains or serotypes of Bluetongue virus.
    Type: Grant
    Filed: November 21, 2008
    Date of Patent: December 8, 2015
    Assignee: Zoetis Services LLC
    Inventor: Joan Plana Duran
  • Phenicol antibacterial agents
    Patent number: 9206126
    Abstract: The present invention provides novel phenicol derivatives, their use for the treatment of infections in mammals, pharmaceutical composition containing these novel compounds, and methods for the preparation of the compounds of formula I
    Type: Grant
    Filed: September 5, 2013
    Date of Patent: December 8, 2015
    Assignee: Zoetis Services LLC
    Inventors: Richard Andrew Ewin, Timothy Allan Johnson, Susan Mary Kult Sheehan, Rajendran Vairagoundar
  • Nucleic acids encoding interleukin-31 monoclonal antibody and uses thereof
    Patent number: 9206253
    Abstract: An isolated antibody that specifically binds to at least one of canine Interleukin-31 (IL-31) or feline IL-31 is provided. Such antibodies can be in the form of diagnostic and/or veterinary compositions useful for treating a pruritic and/or allergic condition in dogs or cats.
    Type: Grant
    Filed: July 8, 2014
    Date of Patent: December 8, 2015
    Assignee: Zoetis Services LLC
    Inventors: Gary F. Bammert, Steven A Dunham
  • Crystalline forms of 1-(5?-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoro-methyl)-4,5-dihydroisoxazol-3-yl)-3?H-spiro[azetidine-3,1?-isobenzofuran]-1-yl)-2-(methylsulfonyl) ethanone
    Patent number: 9200003
    Abstract: The present invention relates to novel crystalline modifications of 1-(5?-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoro-methyl)-4,5-dihydroisoxazol-3-yl)-3?H-spiro[azetidine-3,1?-isobenzofuran]-1-yl)-2-(methylsulfonyl)ethanone. The present invention also describes compositions and methods of treating a parasitic infection or infestation in an animal in need thereof. The present invention also relates to processes for making the crystalline forms.
    Type: Grant
    Filed: August 28, 2013
    Date of Patent: December 1, 2015
    Assignee: Zoetis Services LLC
    Inventors: Denis Billen, Matthew Joseph Birchmeier, Ronald J. VanderRoest
  • PHENYLPYRAZOLE INJECTABLE COMPOSITIONS
    Publication number: 20150297565
    Abstract: This invention relates to a veterinary composition comprising a fluorinated cyclopropylphenylpyrazole. The veterinary composition also comprises a veterinary acceptable carrier including a triglyceride, a solvating agent and optionally an antioxidant. The compositions are injectable. The invention also relates to a method of treating an animal with a parasitic infestation by administering the veterinary composition to the animal in need thereof.
    Type: Application
    Filed: December 11, 2013
    Publication date: October 22, 2015
    Applicant: Zoetis Services LLC
    Inventors: Guy F. DeRose, Stephen L. Secreast, Telma Moreira da Silva
  • Pyrrolo[2,3-d]pyrimidine compounds
    Patent number: 9161939
    Abstract: Described herein is pyrrolo{2,3-d}pyrimidine compounds, their use as Janus Kinase (JAK) inhibitors, pharmaceutical compositions containing this compounds, and methods for the preparation of these compounds.
    Type: Grant
    Filed: February 11, 2015
    Date of Patent: October 20, 2015
    Assignee: Zoetis Services LLC
    Inventors: Mark J. Mitton-Fry, Pamela J. Berlinski, Matthew J. Birchmeier, Jerry W. Bowman, Andrea Joy Gonzales, Steven Glenn Kamerling, Donald Wayne Mann
  • Laidlomycin compositions and methods
    Patent number: 9149456
    Abstract: An animal feed additive composition comprises an effective amount of a laidlomycin, a carrier, magnesium sulfate, and silicon dioxide. Other embodiments include methods of making the animal feed additive compositions, and the use of a laidlomycin in the manufacture of an animal feed additive for increasing the efficiency of feed utilization and rate of weight gain in domestic animals.
    Type: Grant
    Filed: June 15, 2009
    Date of Patent: October 6, 2015
    Assignee: Zoetis Services LLC
    Inventors: Steven Holmes, Janice Cacace
  • Saponin adjuvant compositions and methods relating thereto
    Patent number: 9149520
    Abstract: An adjuvant composition which comprises an anionic macromolecule component particularly an ionic polysaccharide such as DEAE-dextran, and a saponin component, particularly an immunostimulating complex component. Immunogenic compositions comprising an immunogen and this adjuvant composition are also disclosed together with methods of use thereof.
    Type: Grant
    Filed: March 14, 2012
    Date of Patent: October 6, 2015
    Assignee: Zoetis Services LLC
    Inventor: John Walker
  • Phenicol antibacterials
    Patent number: 9145355
    Abstract: The present invention provides novel phenicol derivatives, their use for the treatment of infections in mammals, pharmaceutical compositions containing these novel compounds, and methods for the preparation of these compounds.
    Type: Grant
    Filed: October 5, 2012
    Date of Patent: September 29, 2015
    Assignee: Zoetis Services LLC
    Inventors: Brian A. Duclos, Richard Andrew Ewin, Paul D. Johnson, Timothy Allan Johnson, Graham M. Kyne, Derek James Sheehan, Susan Mary Kult Sheehan, Donald James Skalitzky, Rajendran Vairagoundar
  • Dihydrofuran azetidine derivatives as antiparasitic agents
    Patent number: 9133172
    Abstract: This invention recites dihydrofuran substituted azetidine derivatives of Formula (1) stereoisomers thereof, veterinarily acceptable salts thereof, compositions thereof, and their use as a parasiticide in mammals and birds. The substituents A, R1a, R1b, R1c, R2, R3, R4, R6, and n are as described herein.
    Type: Grant
    Filed: January 29, 2013
    Date of Patent: September 15, 2015
    Assignee: Zoetis Services LLC
    Inventors: Nathan Anthony Logan Chubb, Valerie A. Vaillancourt
  • Spirocyclic isoxazolines as antiparasitic agents
    Patent number: 9131697
    Abstract: The invention recites spirocyclic isoxazoline derivatives of Formula (1) stereoisomers thereof, veterinary or pharmaceutical acceptable salts thereof, compositions thereof, processes for making, and their use as a parasiticide in an animal. The variables W1, W2, W3, W, X, R1a, R1b, R1c, R2, R3, R4, and n are as described herein.
    Type: Grant
    Filed: September 4, 2013
    Date of Patent: September 15, 2015
    Assignee: Zoetis Services LLC
    Inventors: Sanjay Menon, Susan M. K. Sheehan, Valerie A. Vaillancourt
  • PCV/combination vaccine
    Patent number: 9125885
    Abstract: This invention provides a multivalent immunogenic composition including a soluble portion of a Mycoplasma hyopneumoniae (M. hyo) whole cell preparation; and a porcine circovirus type 2 (PCV2) antigen, wherein the soluble portion of the M. hyo preparation is substantially free of both (i) IgG and (ii) immunocomplexes comprised of antigen bound to immunoglobulin.
    Type: Grant
    Filed: March 26, 2013
    Date of Patent: September 8, 2015
    Assignee: Zoetis Services LLC
    Inventors: Gregory P. Nitzel, Jeffrey E. Galvin, John Keith Garrett, James R. Kulawik, II, Tracy L. Ricker, Megan Marie Smutzer
  • PCV/mycoplasma hyopneumoniae/PRRS combination vaccine
    Patent number: 9125886
    Abstract: This invention provides a trivalent immunogenic composition including a soluble portion of a Mycoplasma hyopneumoniae (M.hyo) whole cell preparation; a porcine circovirus type 2 (PCV2) antigen; and a PRRS virus antigen, wherein the soluble portion of the M. hyo preparation is substantially free of both (i) IgG and (ii) immunocomplexes comprised of antigen bound to immunoglobulin.
    Type: Grant
    Filed: March 26, 2013
    Date of Patent: September 8, 2015
    Assignee: Zoetis Services LLC
    Inventors: Gregory P. Nitzel, Jeffrey E. Galvin, John Keith Garrett, James R. Kulawik, II, Tracy L. Ricker, Megan Marie Smutzer
  • vaccine
    Patent number: 9120859
    Abstract: This invention provides an immunogenic composition including a soluble portion of a Mycoplasma hyopneumoniae (M.hyo) whole cell preparation, wherein the soluble portion of the M.hyo preparation is substantially free of both (i) IgG and (ii) immunocomplexes comprised of antigen bound to immunoglobulin.
    Type: Grant
    Filed: March 26, 2013
    Date of Patent: September 1, 2015
    Assignee: Zoetis Services LLC
    Inventors: Jeffrey E. Galvin, Gregory P. Nitzel, John Keith Garrett, James R. Kulawik, Tracy L. Ricker, Megan Marie Smutzer
  • Animal lesion treatment and prevention formulations and methods
    Patent number: 9107418
    Abstract: An illustrative embodiment of an animal lesion treatment and prevention formulation includes a quantity of water, at least one acid provided in the quantity of water and magnesium sulfate as acid/base buffer mixed in the quantity of water with the at least one acid. In some embodiments, an antimicrobial agent comprising at least one antimicrobial metal salt may be provided in the quantity of water with the at least one acid and the magnesium sulfate.
    Type: Grant
    Filed: May 22, 2013
    Date of Patent: August 18, 2015
    Assignee: Zoetis Services LLC
    Inventors: Dennis Smithyman, Rosemary Smithyman, Stephen P. Mixon, Sr.
  • Methods for producing oocysts
    Patent number: 9107865
    Abstract: The present invention provides improved methods and compositions for producing oocysts. The oocysts produced according to the invention find use in the manufacture of vaccines. In preferred embodiments, the present invention provides methods and compositions for the production of Eimeria oocysts. Vaccines containing Eimeria oocysts, sporocysts and/or sporozoites produced according to the present invention may be used to immunize birds against coccidiosis either in ovo or post hatch.
    Type: Grant
    Filed: January 6, 2006
    Date of Patent: August 18, 2015
    Assignee: Zoetis Services LLC
    Inventors: James E. Hutchins, Julius K. Tyczkowski
  • Cellular permissivity factor for viruses and uses thereof
    Patent number: 9102912
    Abstract: The present invention provides methods and compositions related to the generation of host cells permissive for virus growth, particularly Porcine Reproductive and Respiratory Syndrome (PRRS) virus.
    Type: Grant
    Filed: July 12, 2013
    Date of Patent: August 11, 2015
    Assignee: Zoetis Services LLC
    Inventors: Jay Gregory Calvert, Shelly Shields, David E. Slade, Siao-Kun Welch
  • Phenicol antibacterials
    Patent number: 9073894
    Abstract: The present invention provides novel phenicol derivatives of formula I their use for the treatment of infections in mammals, pharmaceutical composition containing these novel compounds, and methods for the preparation of these compounds.
    Type: Grant
    Filed: March 5, 2013
    Date of Patent: July 7, 2015
    Assignee: Zoetis Services LLC
    Inventors: Richard A. Ewin, Timothy Allan Johnson, Susan M. K. Sheehan