Abstract: Disclosed herein are methods and systems for rapid detection of antibiotic resistance of a microorganism in a sample. A modified recombinant phage is also disclosed which comprises an indicator gene in the late gene region. The specificity of infectious agents allows a specific microorganism to be targeted, and an indicator signal may be amplified to optimize assay sensitivity.
Type:
Grant
Filed:
July 3, 2018
Date of Patent:
April 9, 2024
Assignee:
Laboratory Corporation of America Holdings
Inventors:
Minh Mindy Bao Nguyen, Dwight L. Anderson, Jose S. Gil, Stephen E. Erickson, Matthew J. Brown
Abstract: A method of preparing a casting article for use in manufacturing a gas turbine engine part according to an exemplary aspect of the present disclosure includes, among other things, communicating a powdered material to an additive manufacturing system and preparing a casting article that includes at least one trunk and a skin core that extends from the at least one trunk out of the powdered material. A casting article is also disclosed.
Type:
Grant
Filed:
December 3, 2019
Date of Patent:
April 9, 2024
Assignee:
RTX CORPORATION
Inventors:
Tracy A. Propheter-Hinckley, Dominic J. Mongillo, Jr., Benjamin T. Fisk
Abstract: A method is described for producing a vaccine from a neutered pathogenic source. The neutered pathogenic source may be a SARS-COV-2 virus that is neutered with a defined dose of UV-C light. The neutered SARS-COV-2 viral vaccine is administered through an inhalation pump.
Inventors:
Michael Kasten, Edgar Nicolas, Adam Jenson, Shawn Filipek, Andrew Cho, Andrew Grunloh, Pierre-Yves Mossmann, Clifford Krapfl, Michael Herbert, Ross Brinkman
Inventors:
Michael Kasten, Edgar Nicolas, Adam Jenson, Shawn Filipek, Andrew Cho, Andrew Grunloh, Pierre-Yves Mossmann, Clifford Krapfl, Michael Herbert, Ross Brinkman