Abstract: A method is described for producing a vaccine from a neutered pathogenic source. The neutered pathogenic source may be a SARS-COV-2 virus that is neutered with a defined dose of UV-C light. The neutered SARS-COV-2 viral vaccine is administered through an inhalation pump.
Abstract: Disclosed herein are methods and systems for rapid detection of antibiotic resistance of a microorganism in a sample. A modified recombinant phage is also disclosed which comprises an indicator gene in the late gene region. The specificity of infectious agents allows a specific microorganism to be targeted, and an indicator signal may be amplified to optimize assay sensitivity.
Type:
Grant
Filed:
July 3, 2018
Date of Patent:
April 9, 2024
Assignee:
Laboratory Corporation of America Holdings
Inventors:
Minh Mindy Bao Nguyen, Dwight L. Anderson, Jose S. Gil, Stephen E. Erickson, Matthew J. Brown
Abstract: A method of preparing a casting article for use in manufacturing a gas turbine engine part according to an exemplary aspect of the present disclosure includes, among other things, communicating a powdered material to an additive manufacturing system and preparing a casting article that includes at least one trunk and a skin core that extends from the at least one trunk out of the powdered material. A casting article is also disclosed.
Type:
Grant
Filed:
December 3, 2019
Date of Patent:
April 9, 2024
Assignee:
RTX CORPORATION
Inventors:
Tracy A. Propheter-Hinckley, Dominic J. Mongillo, Jr., Benjamin T. Fisk
Abstract: Polynucleotides and vectors can be used for the expression of a transgene in cells, such as liver cells. The expression of the transgene from the polynucleotides and vectors can be useful in gene therapy. Various methods can be used for expressing the transgene from the polynucleotides and vectors in liver cells.
Type:
Grant
Filed:
January 10, 2018
Date of Patent:
March 26, 2024
Assignees:
THE SYDNEY CHILDREN'S HOSPITALS NETWORK (RANDWICK AND WESTMEAD (INCORPORATING THE ROYAL ALEXANDRA HOSPITAL FOR CHILDREN), CHILDREN'S MEDICAL RESEARCH INSTITUTE