Abstract: An enhanced food composition in the form of a frozen or refrigerated food is described, the enhanced food composition comprising a nitrate-containing vegetable, such as beetroot, effectively mixed with a salt content of a food component of the food composition at a specified ratio. The enhanced food composition has the effect to prevent an increase in blood pressure while masking the bad taste of the nitrate-containing vegetable.
Abstract: The current disclosure relates to a culture medium, different methods to generate adult-like cardiomyocytes from pluripotent embryonic stem cells (ESC) and/or (induced) pluripotent stem cells (iPSC) using the medium, in particular from stem cells that differentiated into (foetal) cardiomyocytes, and to kits comprising the medium, or the medium together with differentiated (foetal) cardiomyocytes derived from pluripotent embryonic stem cells (ESC) and/or (induced) pluripotent stem cells (iPSC).
Abstract: Compositions and methods are presented that substantially increase levels of BDNF in blood, and even more pronouncedly exosomal BDNF levels. Suitable compositions include whole coffee fruit extracts and powders that are orally administered at relatively low dosages.
Abstract: A health benefiting daily nutrition includes protein, the protein having a protein weight. The health benefiting daily nutrition includes fiber, the fiber having a fiber weight. The fiber weight is more than 5 g. A ratio of [the protein weight]:[the fiber weight]=1:0.5-1.5.
Type:
Grant
Filed:
March 28, 2022
Date of Patent:
July 2, 2024
Assignee:
Uplifting Results Labs, Inc.
Inventors:
Marc Washington, Ren-Hau Lai, Mengyu Zhao
Abstract: Oral composition and a method for the treatment of coronaviruses infections in humans and animals. The method includes the steps of administering orally a methionine cleaving-enzyme; administering orally or parentally a protease inhibitor; and orally administering pyridoxal-L-phosphate in a fluid.
Abstract: A method of treating telangiectasia in a subject in need thereof is disclosed. The method includes topically applying to skin of said subject in need of treatment of telangiectasia a composition comprising effective amounts of an extract of Centella asiatica leaf and an extract of Vitis vinifera seed to disrupt endothelial tubes in skin.
Abstract: A composition for use in protecting the breast tissue and significantly lowering the high risk for breast cancer development in women includes Ganoderma lucidum, Quercetine, Embilica officinalis, Indole 3 carbinol, Camellia sinensis, Allium sativum, Iodine, and Selenium.
Abstract: The present invention relates to the preparation technical field of traditional Chinese medicine and more particularly, to a traditional Chinese medicine eye drops and the preparation method thereof. The traditional Chinese medicine components of the traditional Chinese medicine eye drops provided by the embodiments of the invention comprise: ginseng Radix et rhizoma of 5-10 wt %, scrophulariae Radix of 15-20 wt %, xanthii Fructus of 5-10 wt %, bovis Calculus sativus of 5-10 wt %, Carthami flos of 5-10 wt %, borneolum of 5-10 wt %, senecionis scandentis herba of 25-35 wt %, fibraureae caulis of 5-15 wt % and motherwort fruit of 5-10 wt %.
Type:
Grant
Filed:
August 11, 2022
Date of Patent:
June 11, 2024
Assignee:
HONG KONG CHINESE MEDICINE OPHTHALMOLOGY INSTITUTE LIMITED
Abstract: The present disclosure relates to human milk compositions and methods of making and using the same. In particular, the disclosure features methods of using human milk compositions to feed subjects before and/or after surgery or medical operations and that are useful in promoting recovery.
Abstract: The invention provides a system for normothermic, ex vivo restoration and preservation of an intact mammalian brain, and other organs. In certain aspects, the system is capable of preserving a brain as well as other organs, maintaining cellular integrity and cellular function for hours post mortem or after global ischemia. The invention also provides synthetic brain perfusate formulations, including a novel brain perfusion medium (BPM), which are able to reduce reperfusion injury, stimulate recovery from hypoxia, prevent edema and metabolically support the energy needs of brain function.
Type:
Grant
Filed:
February 8, 2019
Date of Patent:
June 4, 2024
Assignee:
Yale University
Inventors:
Stefano Daniele, Nenad Sestan, John Silbereis, Zvonimir Vrselja
Abstract: The invention relates to the technical field of medicines, and particularly relates to a multi-component injection and preparation processes and applications thereof. In the present invention, the effective ingredients of safflower Carthamus, Red Paeony Root, Ligusticum wallichii, Radix salvia miltiorrhizae and Angelica sinensis are analyzed and a multi-component injection is prepared via the modem pharmaceutical preparation technology. The study proves that the multi-component injection of the invention has therapeutic effects on Sepsis.
Type:
Grant
Filed:
April 20, 2021
Date of Patent:
May 21, 2024
Assignee:
TIANJIN CHASE SUN PHARMACEUTICAL CO. LTD
Abstract: The present invention provides a coconut sap inflorescence powder compositions to provide symptomatic or prophylactic treatment of human disorder that has enriched vitamins, minerals, fat, carbohydrates and proteins. The invention also provides a process for producing such powders by spray drying or freeze drying. The powdered compositions and dosage forms are useful in the treatment of drug induced nephrotoxicity, alcoholic liver damage, and performance enhancement when administered orally.
Abstract: A method includes ingesting a first portion of a first supplement within three hours prior to boarding an airplane for a flight and ingesting a first portion of a second supplement within three hours prior to boarding an airplane for a flight. The method includes ingesting a second portion of the second supplement and ingesting a first portion of a third supplement during the flight. The method includes ingesting a second portion of the first supplement alongside a second portion of the third supplement within three hours of the airplane landing. The first supplement includes a probiotic. The second supplement includes an amount of at least one of gluconate, sorbitol, xylitol, maltodextrin, peppermint oil, lemon oil, lime oil, stevia leaf extract, ginger extract, steric acid, or probiotic. The third supplement includes at least one of glutathione, Brassica Oleracea sprouts, glucosinolates, glucoraphanin, or rice flour.
Abstract: Disclosed are means, methods, and therapeutic compositions for prevention of memory loss during situations of neuroinflammation. In one embodiment the invention teaches administration of the therapeutic combination of ingredients comprising of pterostilbene, Nigella sativa, sulforaphane, and epigallocatechin-3-gallate (EGCG) to a mammal suffering from inflammation in order to preserver memory function.
Abstract: As a technique for proliferating neural crest cells without reducing differentiation capacity, provided is a method for producing neural crest cells, comprising the steps of: (1) obtaining neural crest cells; and (2) suspension-culturing the neural crest cells in a medium comprising a GSK3? inhibitor and a basic fibroblast growth factor (bFGF), wherein the medium comprises the GSK3? inhibitor with a concentration that exhibits an effect equivalent to that exhibited by CHIR99021 with a concentration of higher than 1 ?M and lower than 5 ?M.
Type:
Grant
Filed:
November 29, 2018
Date of Patent:
April 16, 2024
Assignees:
Kyoto University, Takeda Pharmaceutical Company Limited
Abstract: A transmucosal psychoactive alkaloid composition including a psychoactive alkaloid extract or synthetic psychoactive alkaloid. The alkaloids in the extract are predominantly dephosphorylated rather than phosphorylated. The transmucosal psychoactive alkaloid composition also includes a mucoadhesive polymer, a carrier, and optional further excipients. The non-ingestive composition may be taken orally through the mucosa. A process for obtaining an oral transmucosal psychoactive alkaloid composition includes dephosphorylating the alkaloid during extraction, purifying the extracted alkaloid and standardizing to a specific concentration by adding measured quantities of excipients.
Type:
Grant
Filed:
August 26, 2023
Date of Patent:
April 16, 2024
Assignee:
Psilo Scientific Ltd.
Inventors:
Ryan Moss, Benjamin Lightburn, Lisa Ranken
Abstract: The invention provides an animal chew toy comprising a dental care composition, wherein the dental care composition comprises at least one peroxidase and at least one oxidase.
Abstract: An acellular, anion-depleted platelet-derived peptide-rich composition comprising proteins, polypeptides and peptides <10 kDa in size, wherein the composition has anti-microbial and/or anti-inflammatory activity is disclosed. The composition can be substantially free of non-active and immunogenic factors. The composition can have a platelet-to-bacteria ratio ?1000:1. The composition can comprise plasma at a range of ?10% to ?50% plasma, optionally about 10% plasma. Methods of using the composition are also disclosed.
Type:
Grant
Filed:
September 30, 2020
Date of Patent:
April 9, 2024
Assignees:
North Carolina State University, The Trustees of the University of Pennsylvania
Inventors:
Jessica M. Gilbertie, Lauren V. Schnabel, Thomas P. Schaer
Abstract: Provided is a composition for preventing, alleviating or treating dry eye syndrome, containing an Aucuba japonica extract as an active ingredient. The composition containing an Aucuba japonica extract can be effectively used in the prevention, alleviation or treatment of dry eye syndrome.
Type:
Grant
Filed:
October 30, 2018
Date of Patent:
March 26, 2024
Assignee:
INDUSTRIAL COOPERATION FOUNDATION CHONBUK NATIONAL UNIVERSITY
Abstract: A biologically active food additive for normalizing the function of the thyroid gland comprises roots or rhizome or the above-ground part of white cinquefoil, or a mixture thereof, purple echinacca and laminaria, with the following ratio of components in mass %: 10-75 of white cinquefoil, 10-50 of purple echinacea and 10-80 of laminaria. The technical result of the invention is the showing of increased efficacy in treating thyroid gland disorders and enhancing the body's immune status, with no side of effects.
Type:
Grant
Filed:
February 13, 2017
Date of Patent:
March 19, 2024
Assignee:
Parapharm LLC
Inventors:
Vyacheslav N Trifonov, Yulia A. Elistratova, Konstantin G. Elistratov, Natalia V. Kurus'