Patents Examined by Aaron J Kosar
  • Compositions for enhancing hyperthermia therapy
    Patent number: 11896624
    Abstract: A composition for decreasing proliferation of cancer cells undergoing hyperthermia therapy is described. Such compositions can include a combination of selenium and fish oil. The respective quantities of selenium and fish oil are provided in amounts effective to synergistically increase the sensitivity of the cancer cells to temperatures in excess of 37° C.
    Type: Grant
    Filed: July 27, 2022
    Date of Patent: February 13, 2024
    Inventor: Houn Simon Hsia
  • Erythrocyte-binding therapeutics
    Patent number: 11884721
    Abstract: Peptides that specifically bind erythrocytes are described. These are provided as peptidic ligands having sequences that specifically bind, or as antibodies or fragments thereof that provide specific binding, to erythrocytes. The peptides may be prepared as molecular fusions with therapeutic agents, tolerizing antigens, or targeting peptides. Immunotolerance may be created by use of the fusions and choice of an antigen on a substance for which tolerance is desired. Fusions with targeting peptides direct the fusions to the target, for instance a tumor, where the erythrocyte-binding ligands reduce or entirely eliminate blood flow to the tumor by recruiting erythrocytes to the target.
    Type: Grant
    Filed: January 7, 2021
    Date of Patent: January 30, 2024
    Assignee: École Polytechnique Fédérale de Lausanne (EPFL)
    Inventors: Jeffrey A. Hubbell, Stephan Kontos, Karen Y. Dane
  • DHA enriched polyunsaturated fatty acid compositions
    Patent number: 11872201
    Abstract: There is provided a vegetable-based lipid composition comprising very high levels of DHA, together with at least one other long-chain polyunsaturated fatty acid (typically as fatty acid esters). The composition typically contains low levels of EPA and palmitic acid. The composition is obtainable from a single source by conventional processing methods, and has improved stability properties.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: January 16, 2024
    Assignee: Nuseed Nutritional US Inc.
    Inventor: Stuart Littler
  • Composition for preventing age-related metabolic and tissue degenerative changes
    Patent number: 11873519
    Abstract: A composition and method for reversing or preventing age-related metabolic and tissue degenerative changes in individuals. The method includes administering, orally, an effective amount of a first composition having methioninase enzyme. The method further includes administering, by a route other than the oral route, such as a parenteral route, an effective amount of a second composition having methioninase enzyme. The method further includes the steps of orally and/or parentally administering pyridoxal-L-phosphate.
    Type: Grant
    Filed: May 25, 2022
    Date of Patent: January 16, 2024
    Inventors: Qinghong Han, Robert M Hoffman
  • Oral cavity treatments
    Patent number: 11872258
    Abstract: Embodiments of the invention include a system having a plant stem cell product and a delivery device configured to deliver an effective amount of the plant stem cell product to the oral cavity or nasopharynx. In some embodiments, the delivery device may include an aerosolizing device, an adherent dressing, a tooth-adherent flexible strip, a treatment tray, a viscous adherent carrier, a brush, a paste, a flosser, a dissolving oral strip, a gum, a chew, a smoking material, a nasal packing, or a lozenge. The plant stem cell products may include encapsulated extracts of plant stem cells, such as food species stem cells, spice or other seasoning stem cells, or medicinal plant stem cells.
    Type: Grant
    Filed: November 24, 2019
    Date of Patent: January 16, 2024
    Assignee: StemStix, Inc.
    Inventor: Maryam Rahimi
  • Therapeutic composition including carbonated solution
    Patent number: 11864570
    Abstract: The present invention is directed to a therapeutic composition including an active therapeutic ingredient combined with a liquid or solution based carbonated beverage. The invention as described details the use or administration of the therapeutic composition so as to treat a variety of ailments. The present invention is also directed to a method of administering the therapeutic composition to an individual for the purposes of alleviating an ailment. In a further arrangement, the therapeutic composition is provided to a user as a pre-packaged volume containing a single effective dose of the therapeutic agent.
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: January 9, 2024
    Assignee: VISION PHARMA, LLC
    Inventor: Sander S. Busman
  • Anthocyanin powder extract and process for production
    Patent number: 11865131
    Abstract: The present invention relates to a process for producing an extract powder from a fruit material of e.g. berry fruits, wherein anthocyanins are enriched from the fruit material, and to the product obtainable by the process. In the process according to the invention, anthocyanins are enriched via a cation exchanger. By eluting the anthocyanins from the cation exchanger by means of L-arginine, the process has the advantage that no salt needs to be purified from the eluate to produce an extract powder suitable for use as a dietary supplement.
    Type: Grant
    Filed: November 15, 2021
    Date of Patent: January 9, 2024
    Assignee: Deutsches Institut für Lebensmitteltechnik e.V.
    Inventor: Andreas Juadjur
  • Plant extract obtained from plant leaves which has an IC50 value to inhibit a-glucosidase I at a concentration of less than 90 uG/ml, compositions containing same, method of extraction and uses thereof
    Patent number: 11865155
    Abstract: An extract from leaves of mulberry is disclosed. The extract has an IC50 value sufficient to inhibit a-glucosidase I. The extract may comprise 5-40% (w/w) total imino sugars and 20-70% (w/w) total amino acids. The extract may reduce the production of melanin for the treatment of such ailments or diseases caused by pigmentation as freckle, chloasma, striae gravidarum, sensile plaque and melanoma. The extract may also control blood glucose level.
    Type: Grant
    Filed: July 2, 2021
    Date of Patent: January 9, 2024
    Inventors: Chen Xie, Yingshu Zou
  • Nutraceutical gels
    Patent number: 11857593
    Abstract: A nutraceutical food product includes a solid matrix and a liquid combined into a gel. The nutraceutical food product may include an immune modulator, such as transfer factor and/or a nanofraction immune modulator. A fruit component may be included in the nutraceutical food product. The fruit component may include at least one oligoproanthocyanidin-containing fruit, such as açai.
    Type: Grant
    Filed: July 30, 2019
    Date of Patent: January 2, 2024
    Assignee: 4Life Patents, LLC
    Inventors: Brent M. Vaughan, Calvin W. McCausland, David A. Lisonbee
  • Multi-purpose cosmetic compositions
    Patent number: 11857667
    Abstract: A method for treating the skin of a subject in need thereof is disclosed. The method includes topically applying to the skin of the subject a cosmetic composition that includes an effective amount of an aqueous, alcoholic, or aqueous-alcoholic extract of Silybum marianum and an aqueous, alcoholic, or aqueous-alcoholic extract of Momordica grosvenori fruit.
    Type: Grant
    Filed: October 21, 2020
    Date of Patent: January 2, 2024
    Assignee: MARY KAY INC.
    Inventors: Tiffany Florence, Michelle Hines, David Gan
  • Composition comprising sapogenin and exosome as effective ingredient
    Patent number: 11850297
    Abstract: A composition containing a combination of exosomes and sapogenin as an active ingredient is disclosed. The composition is able to promote preadipocyte proliferation, lipid uptake into adipocytes, and/or adipogenesis, but reduce the cytotoxicity caused by sapogenin. Therefore, the composition can reduce side effects on the body or skin, and can be used such that it is conveniently applied to a dissatisfactory part of the body showing flaws which look less plump due to a deficit in lipids and the like, or an area of the skin showing flaws caused by a deficit in lipids.
    Type: Grant
    Filed: March 19, 2020
    Date of Patent: December 26, 2023
    Assignee: ExoCoBio Inc.
    Inventors: Yong Weon Yi, Byong Seung Cho
  • Topical formulation and uses thereof
    Patent number: 11844820
    Abstract: The present invention provides a topical formulation including (i) comfrey or a comfrey-derived compound, or an analogue or derivative thereof and (ii) a penetration enhancer, and optionally including tannic acid, or an analogue or derivative thereof. The present invention also provides a topical formulation including (i) comfrey or a comfrey-derived compound, or an analogue or derivative thereof, and (ii) tannic acid, or an analogue or derivative thereof, optionally including a penetration enhancer. Also provided are kits and methods of prophylactic or therapeutic treatment of inflammatory and/or degenerative conditions using the combination of active ingredients as herein described.
    Type: Grant
    Filed: April 29, 2019
    Date of Patent: December 19, 2023
    Assignee: ARTHRITIS RELIEF PLUS LTD.
    Inventors: Larry McKay, Kanu Patel, Robert John Capon
  • Fenugreek extract for the treatment of poly cystic ovarian syndrome (PCOS)
    Patent number: 11844821
    Abstract: Discloses is a single herb extract for the treatment of PCOS (Poly Cystic Ovarian Syndrome) when given in oral dosage form as capsules of 500 mg, twice a day for period of time ranging from 30-90 days. The extract is obtained from fenugreek seeds using a specific method of extraction and comprises five furostanolicsaponins present in synergistic ratios as in Table 1 and having analytical profile as in FIG. 1.
    Type: Grant
    Filed: August 31, 2020
    Date of Patent: December 19, 2023
    Inventor: Pawan Kumar Goel
  • Therapeutic composition including carbonated solution
    Patent number: 11844364
    Abstract: The present invention is directed to a therapeutic composition including an active therapeutic ingredient combined with a liquid or solution based carbonated beverage. The invention as described details the use or administration of the therapeutic composition so as to treat a variety of ailments. The present invention is also directed to a method of administering the therapeutic composition to an individual for the purposes of alleviating an ailment. In a further arrangement, the therapeutic composition is provided to a user as a pre-packaged volume containing a single effective dose of the therapeutic agent.
    Type: Grant
    Filed: March 17, 2020
    Date of Patent: December 19, 2023
    Assignee: VISION PHARMA, LLC
    Inventor: Sander S. Busman
  • Pharmaceutical composition based on plant raw materials: #2.1
    Patent number: 11839636
    Abstract: A pharmaceutical composition containing dry powder of pine (Pinus) needles and dry peels and pits of grapes extract and pharmaceutically acceptable additive, dry extracts of ginger (Zingiber officinale), green tea (Camellia sinensis), yellow ginger (Curcuma longa), yellow mustard (Brassica hirta) seeds, white pepper, pomegranate (Punica granatum) bark and dry powder of pomegranate (Punica granatum) juice.
    Type: Grant
    Filed: July 27, 2022
    Date of Patent: December 12, 2023
    Inventors: Babry Oren, Sasha Moshe
  • Capsule-containing pouched product for oral use
    Patent number: 11832640
    Abstract: A pouched product adapted for release of a releasable component therefrom is provided herein. The pouched product can include a water-permeable fabric pouch formed so as to define a cavity therein, and a composition contained within the cavity of the water-permeable fabric pouch, the composition including one or more releasable components that are released from the composition under mouth conditions and that are capable of movement through the water-permeable fabric pouch. The composition includes nicotine and at least one particulate non-tobacco material. The pouched product also includes at least one capsule contained within the cavity of the water-permeable fabric pouch, the capsule having a capsule wall surrounding an inner payload comprising at least one botanical.
    Type: Grant
    Filed: May 5, 2022
    Date of Patent: December 5, 2023
    Assignee: R.J. Reynolds Tobacco Company
    Inventors: Paul Stuart Chapman, David Troy Turfler
  • Pore minimizer
    Patent number: 11833243
    Abstract: A method for reducing the appearance of a skin pore in skin of a subject in need thereof is disclosed. The method can include topically applying to the skin pore a composition comprising effective amount of Albizia julibrissin bark extract, and hydrolyzed soy flour, wherein topical application of the composition reduces the appearance of the size of the skin pore.
    Type: Grant
    Filed: May 13, 2021
    Date of Patent: December 5, 2023
    Assignee: MARY KAY INC.
    Inventors: David Gan, Geetha Kalahasti, Lisha Van Pelt
  • Skin care formulations
    Patent number: 11833242
    Abstract: Skin care formulations that function via a multi-modal approach are provided in some embodiments in which select ingredients work together to protect skin from ultraviolet light, hydrates the skin and provides antioxidant properties.
    Type: Grant
    Filed: August 5, 2022
    Date of Patent: December 5, 2023
    Assignee: COLORESCIENCE, INC.
    Inventors: Patricia McGill Boland, Deborah Eileen Gregg Bouche, John Anthony Garruto, Bethany Ann McCarver
  • Redness correcting skin care formulations
    Patent number: 11826457
    Abstract: In some embodiments, soothing redness correction formulations are provided. In other embodiments, formulations to treat skin discoloration via a multi-modal approach are provided in some embodiments in which select ingredients work together to effectively brighten skin and treat hyperpigmentation. In yet other embodiments, certain formulations are renewal formulations adapted to treat the eye area to, for example, reduce laxity, puffiness, wrinkles and/or dark circles around the eye.
    Type: Grant
    Filed: April 18, 2019
    Date of Patent: November 28, 2023
    Assignee: Colorescience, Inc.
    Inventors: Patricia McGill Boland, Deborah Eileen Gregg Bouche, John Anthony Garruto, Bethany Ann McCarver
  • Composition for treating diarrhea
    Patent number: 11819529
    Abstract: Disclosed in the present invention is a composition for treating diarrhea, comprising the following components calculated by weight ratio: Colocasia esculenta and antidiarrheal foods. The composition of the present invention has low cost, available raw materials, is safe and non-toxic, and is suitable for industrial production. The antidiarrheal effect of the product is remarkable. The rehabilitation time for the common diarrhea is 24-48 hours, and for the diarrhea caused by rotavirus is 48-72 hours, and the rehabilitation time is shortened by 2.5 days on average. The effective rate for persistent diarrhea within 5 days is 90.16%. For diarrhea of infants with milk protein allergy during the addition of supplementary feeding, six to eight kinds of foods can be added in one month, and thus the composition is especially suitable for infants and young children.
    Type: Grant
    Filed: August 8, 2019
    Date of Patent: November 21, 2023
    Assignees: Tianjin Geonatural Technology Co., Ltd. (CN)
    Inventors: Jingjing Cao, Weiran Cui, Yueran Cui